Education
School — Major — Degree | Duration |
---|---|
國立臺灣大學 — 解剖學暨細胞生物學研究所(畢) — 博士 Doctorate, Anatomy and Cell Biology, National Taiwan University |
2003/09 — 2008/06 |
國立成功大學 — 細胞生物與解剖學研究所(畢) — 碩士 Master, Cell Biology and Anatomy, National Cheng-Kung University |
2000/09 — 2002/06 |
國立成功大學 — 護理學系(畢) — 學士 Bachelor, Nursing, National Cheng-Kung University |
1996/09 — 2000/06 |
Intramural Experience
Office/Department/Institute | Position | Duration |
---|---|---|
醫學院研發組 Research and Development Division | Head | 2024/08/01 — 2025/07/31 |
解剖學科 Department of Anatomy | Professor | 2022/08/01 — |
解剖學科 Department of Anatomy | Associate Professor | 2016/02/01 — 2022/07/31 |
解剖學科 Department of Anatomy | Assistant Professor | 2010/08/01 — 2016/01/31 |
解剖學科 Department of Anatomy | Assistant Professor | 2010/03/03 — 2010/07/31 |
Extramural Experience
DEPNO | Position- Office/Department/Institute | Duration |
---|---|---|
國立成功大學心血管疾病研究中心 | 博士後助理研究員 | 0980801 — 0981130 |
國立臺灣大學醫學院醫學系解剖學暨細胞生物學科 | 博士後研究人員 | 0970801 — 0980731 |
Discipline
NO | Discipline | Expertise |
---|---|---|
1 | 生物醫農類 Biology, Medicine and Agriculture | 解剖、病理及法醫 Anatomy, Pathology and Forensic Medicine |
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
毒物、癌症、中草藥物。醫學教育
Area(s) of Expertise & Research
生殖、內分泌、訊息傳導、中草藥保健食品開發
endocrine, reproductive system, signal transduction, herbal medicine
Publication
NO | Publication |
---|---|
1 | 體外與體內模式探討東格阿里萃取物緩解脂肪肝的機制: 活化AMPK及自噬流 Investigation of Eurycoma longifolia Extract on Alleviating Steatosis by Using in vivo and in vitro Steatotic Models: Mechanisms Through Activation of AMPK and Autophagic Flux |
2 | Clerodane diterpene induces apoptosis/anoikis and suppresses migration and invasion of human bladder cancer cells through the histone deacetylases, integrin-focal adhesion kinase, and matrix metalloproteinase 9 signalling pathways Clerodane diterpene induces apoptosis/anoikis and suppresses migration and invasion of human bladder cancer cells through the histone deacetylases, integrin-focal adhesion kinase, and matrix metalloproteinase 9 signalling pathways |
3 | 香椿根精油誘發人類腎癌細胞粒線體依賴凋亡透過Akt, mTOR and NF-κB 訊息傳遞路徑 Induction of mitochondrial-dependent apoptosis by essential oil of Toona sinensis root through Akt, mTOR and NF-κB signalling pathways in human renal cell carcinoma cells |
4 | The Role of Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin. The Role of Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin. |
5 | Phytochemicals from Polyalthia Species: Potential and Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Chemoprevention Activities Phytochemicals from Polyalthia Species: Potential and Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Chemoprevention Activities |
6 | 16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways. 16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways. |
7 | Propofol induces apoptosis by activating caspases and the MAPK pathways, and inhibiting the Akt pathway in TM3 mouse Leydig stem/progenitor cells. Propofol induces apoptosis by activating caspases and the MAPK pathways, and inhibiting the Akt pathway in TM3 mouse Leydig stem/progenitor cells. |
8 | The novel camptothecin derivative, CPT211, induces cell cycle arrest and apoptosis in models of human breast cancer. The novel camptothecin derivative, CPT211, induces cell cycle arrest and apoptosis in models of human breast cancer. |
9 | 初級培養大鼠腎上腺皮質細胞與固醇類生合成功能分析 Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions. |
10 | 丙泊酚可能增加凋亡蛋白酶及MAPK路徑,抑制akt而導致MA-10小鼠萊氏腫瘤細胞株凋亡 Propofol may increase caspase and MAPK pathways, and suppress the Akt pathway to induce apoptosis in MA‑10 mouse Leydig tumor cells |
11 | 砷誘發小鼠萊氏腫瘤細胞MA10凋亡透過凋亡蛋白酶路徑活化 Arsenic compounds induce apoptosis through caspase pathway activation in MA‑10 Leydig tumor cells |
12 | Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways |
13 | 16-Hydroxycleroda-3,13-dien-15,16-olide 引發人類腎癌細胞失巢凋亡: 粘著斑拆卸和信息路徑 16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: Involvement of focal adhesion disassembly and signaling |
14 | 冬蟲夏草與蟲草素在熊性生殖系統功能性研究:評論 Functional study of Cordyceps sinensis and cordycepin in male reproduction: A review |
15 | 16-hydroxycleroda-3, 13-dien-15, 16-olide抑制腎臟癌生長與促進粒線體依賴凋亡透過 Akt, mTOR, and MEK-ERK路徑 16-hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells. |
16 | 香椿葉水萃取液抑制腎癌細胞生長與移行透過JAK2/stat3,Akt, MEK/ERK, 及mTOR/HIF2a路徑 Aqueous extracts of Toona sinensis leaves inhibits renal carcinoma cell growth and migration through JAK2/stat3, Akt, MEK/ERK, and mTOR/HIF-2a pathways |
17 | 速眠安造成小鼠萊氏腫瘤細胞凋亡透過調控caspase、內質網壓力與自噬作用 Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells |
18 | 纖維母細胞生長因子9與其接受器在發育中小鼠睪丸之表現形態 The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes |
19 | 香椿刺激腎上腺細胞皮質酮生成之機制 Mechanism of Toona sinensis-stimulated adrenal steroidogenesis in primary rat adrenal cells |
20 | 蟲草素合併順鉑與/或紫杉醇在小鼠腫瘤萊氏細胞造成之凋亡效應 Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells |
21 | 香椿葉水萃取液引發人類腎癌細胞凋亡透過活性氧與活化內生性凋亡路徑 Toona sinensis (aqueous leaf extracts) induces apoptosis through the generation of ROS and activation of intrinsic apoptotic pathways in human renal carcinoma cells |
22 | 香椿葉萃取物抑制敗血症引起之發炎反應 Toona sinensis leaf aqueous extract displays activity against sepsis in both in vitro and in vivo models |
23 | 油酸引發大鼠心肌細胞黏附接合瓦解是透過fyn及casein蛋白激酶的機制 Oleic acid induces adherens junction disassembly in rat neonatal cardiomyocytes through mechanisms involving fyn kinase and casein kinase 1 |
24 | 五味子素促進海馬迴神經細胞樹突生長與突觸形成 Schisandrin enhances dendrite outgrowth and synaptogenesis in primary cultured hippocampal neurons |
25 | 冬蟲夏草刺激MA-10萊氏腫瘤細胞之機制 Regulatory mechanisms of Cordyceps sinensis on steroidogenesis in MA-10 mouse Leydig tumor cells |
26 | 蛋白激酶C調控腺甘刺激的大鼠腎上腺皮質細胞固醇類生合成作用 Protein kinase Cμ mediates adenosine-stimulated steroidogenesis in primary rat adrenal cells |
27 | 蟲草素引起甲狀腺癌細胞凋亡透過鈣離子-鈣蛋白酶-硫胱氨酸蛋白酶-多聚酶訊息傳遞路徑 Cordycepin induces apoptosis of CGTH W-2 thyroid carcinoma cells through the calcium-calpain-caspase 7-PARP pathway. |
Project
NO |
YEAR — Source — No — Type
Project Name
|
Duration |
---|---|---|
1 |
113 — M 高醫(種子計畫) — KMU-M114008 —
Clerodane diterpenes對黑色素瘤的抗癌機制探討:單一與合併療法( )
|
2025/01/01 ~ 2025/12/31 |
2 |
112 — N 國科會(原科技部) — NSTC112-2410-H-037-027 — 1 個人型
探究與實作教學模組提升醫學大學生解剖學學習自我效能、復原力及學習成效之探討( )
|
2023/08/01 ~ 2024/07/31 |
3 |
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-022-B — 8 大專學生研究計畫
113年度大專學生研究計畫-陳冠穎(醫學2)( )
|
2024/07/01 ~ 2025/02/28 |
4 |
111 — M 高醫(種子計畫) — KMU-M112031 —
超臨界二氧化碳香椿根萃取物的抗黑色素瘤機制探討( )
|
2023/01/01 ~ 2023/12/31 |
5 |
110 — M 高醫(種子計畫) — KMU-M111015 —
16-hydroxycleroda-3,13-dien-15,16-ol ide 抗發炎活性改善 imiquimod 誘發乾癬 的功效評估( )
|
2022/01/01 ~ 2022/12/31 |
6 |
109 — N 國科會(原科技部) — MOST109-2635-B-037-001 — 1 個人型
探討香椿萃取物透過短鏈脂肪酸抑制肥胖的機制( )
|
2020/08/01 ~ 2021/07/31 |
7 |
108 — G 農業部(原農委會) — 109農科-17.1.6-檢-B1 —
伴侶動物用含中草藥動物用藥品檢驗登記審查基準之研提( )
|
2020/01/01 ~ 2020/12/31 |
8 |
107 — M 高醫(種子計畫) — KMU-M108024 —
探討香椿萃取物改善西式飲食引發之非酒精性脂肪肝之研究( )
|
2019/01/01 ~ 2019/12/31 |
9 |
106 — M 高醫(種子計畫) — KMU-M106015 —
探討香椿葉萃取物對睪丸萊氏細菌細胞固醇類生合成之機制( )
|
2018/01/01 ~ 2018/12/31 |
10 |
104 — N 國科會(原科技部) — NSC102-2320-B-037-008-MY3 — 1 個人型
香椿萃取液刺激腎上腺皮質細胞固醇類生合作機制與生理功能之研究(3/3)( )
|
2015/08/01 ~ 2017/07/31 |
11 |
103 — N 國科會(原科技部) — NSC102-2320-B-037-008-MY3 — 1 個人型
香椿萃取液刺激腎上腺皮質細胞固醇類生合作機制與生理功能之研究(2/3)( )
|
2014/08/01 ~ 2017/07/31 |
12 |
102 — N 國科會(原科技部) — NSC102-2320-B-037-008-MY3 — 1 個人型
香椿萃取液刺激腎上腺皮質細胞固醇類生合作機制與生理功能之研究(1/3)( )
|
2013/08/01 ~ 2017/07/31 |
13 |
101 — N 國科會(原科技部) — NSC101-2320-B-037-024 — 1 個人型
香椿抗癌效果於腎臟癌的應用( )
|
2012/08/01 ~ 2013/07/31 |
14 |
100 — Q 新聘教師計畫(校內) — KMU-Q110024 —
香樁對腎上腺細胞的影響( )
|
2011/12/15 ~ 2012/12/31 |
15 |
099 — Q 新聘教師計畫(校內) — Q100016 —
腺苷引起腎臟癌細胞凋亡之機制探討( )
|
2011/01/01 ~ 2011/12/31 |