Education
| School — Major — Degree | Duration |
|---|---|
|
國立陽明大學 — 生物醫學影像暨放射科學系(畢) — 博士 Doctorate, Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University |
2002/09 — 2008/01 |
|
國立陽明大學 — 醫學放射技術學系(畢) — 學士 Bachelor, Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University |
1996/09 — 2000/06 |
Intramural Experience
| Office/Department/Institute | Position | Duration |
|---|---|---|
| 醫學影像暨放射科學系 Department of Medical Imaging and Radiological Sciences | Associate Professor | 2016/08/01 — |
| 醫學影像暨放射科學系 Department of Medical Imaging and Radiological Sciences | Assistant Professor | 2009/08/01 — 2016/07/31 |
Extramural Experience
| DEPNO | Position- Office/Department/Institute | Duration |
|---|---|---|
| 中臺科技大學 | 助理教授 | 0961105 — 0970731 |
Discipline
| NO | Discipline | Expertise |
|---|---|---|
| 1 | 生物醫農類 Biology, Medicine and Agriculture | 放射線科及核子醫學科 Division of Radiology and Nuclear Medicine |
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
分子及基因影像技術及應用研究、基因體醫學及藥物之研究
Molecular imaging and pharmacogenomics studies
Area(s) of Expertise & Research
分子影像；輻射生物學 ; 放射腫瘤生物學
molecular imaging, radiobiology, radiation oncology
Publication
| NO | Publication |
|---|---|
| 1 | Exosomes Derived from Irradiated-Prostate Cancer Cells Promote Cancer Progression Exosomes Derived from Irradiated-Prostate Cancer Cells Promote Cancer Progression |
| 2 | 單條和叢集染色體自動辦識之方法 Automated identification of single and clustered chromosomes for metaphase image analysis |
| 3 | Activities of imipenem-relebactam combination against carbapenem-nonsusceptible Enterobacteriaceae in Taiwan. Activities of imipenem-relebactam combination against carbapenem-nonsusceptible Enterobacteriaceae in Taiwan. |
| 4 | Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe |
| 5 | In vitro and in vivo assessments of inspired ag/80S bioactive nanocomposites against carbapenem-resistant Klebsiella pneumoniae. In vitro and in vivo assessments of inspired ag/80S bioactive nanocomposites against carbapenem-resistant Klebsiella pneumoniae. |
| 6 | Enhancement of IUdR Radiosensitization in Cancer Therapy by Low-Energy Transmission X Ray Irradiation Enhancement of IUdR Radiosensitization in Cancer Therapy by Low-Energy Transmission X Ray Irradiation |
| 7 | Clinical significance of olfactory dysfunction in patients of COVID-19. Clinical significance of olfactory dysfunction in patients of COVID-19. |
| 8 | Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization |
| 9 | Multiplexed Molecular Imaging Strategy Integrated with RNA Sequencing in the Assessment of the Therapeutic Effect of Wharton’s Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles for Osteoporosis Multiplexed Molecular Imaging Strategy Integrated with RNA Sequencing in the Assessment of the Therapeutic Effect of Wharton’s Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles for Osteoporosis |
| 10 | Evaluation of the Organotellurium Compound AS101 for Treating Colistin- and Carbapenem-Resistant Klebsiella pneumoniae Evaluation of the Organotellurium Compound AS101 for Treating Colistin- and Carbapenem-Resistant Klebsiella pneumoniae |
| 11 | Combination of Colistin and Azidothymidine Demonstrates Synergistic Activity against Colistin-Resistant, Carbapenem-Resistant . Combination of Colistin and Azidothymidine Demonstrates Synergistic Activity against Colistin-Resistant, Carbapenem-Resistant . |
| 12 | In Vitro and In Vivo Evaluations of β-Lactam/β-Lactamase Mono- and Combined Therapies against Carbapenem-Nonsusceptible Enterobacteriaceae in Taiwan. In Vitro and In Vivo Evaluations of β-Lactam/β-Lactamase Mono- and Combined Therapies against Carbapenem-Nonsusceptible Enterobacteriaceae in Taiwan. |
| 13 | Correlation of 18F-FDG uptake and thyroid cancer stem cells Correlation of 18F-FDG uptake and thyroid cancer stem cells |
| 14 | 急慢性酒精中毒對大鼠腦部代謝乙酸能力的影響 Effects of the acute and chronic ethanol intoxication on acetate metabolism and kinetics in the rat brain |
| 15 | Fli-1過度表現和星狀細胞瘤的預後差有關連性 Overexpression of Fli-1 in astrocytoma is associated with poor prognosis |
| 16 | 針對鼻咽癌放射治療後海馬迴遭受微劑量曝露後的認知功能評估 Prognosis of Hippocampal Function after Sub-lethal Irradiation Brain Injury in Patients with Nasopharyngeal Carcinoma. |
| 17 | 利用無模式化時空間群聚法來估計fMRI神經反應活度 Adapted estimate of neural activity based on blood-oxygen-level dependent signal by a model-free spatio-temporal clustering analysis |
| 18 | 利用類神經及支持向量系統來進行EEG橫斷面靜坐經驗分析 A cross-sectional evaluation of meditation experience on electroencephalography data by artificial neural network and support vector machine classifiers |
| 19 | Quantitative Measurement of the Thyroid Uptake Function of Mouse by Cerenkov Luminescence Imaging Quantitative Measurement of the Thyroid Uptake Function of Mouse by Cerenkov Luminescence Imaging |
| 20 | 新型穿透式X光儀器的物理及生物醫學特性 The physical and biomedical characteristics of the novel transmission type X-ray equipment |
| 21 | Ovatodiolide of Anisomeles indica, exerts the anti-cancer potential on pancreatic cancer cell lines through STAT3 and NF-κB regulation Ovatodiolide of Anisomeles indica, exerts the anti-cancer potential on pancreatic cancer cell lines through STAT3 and NF-κB regulation |
| 22 | Characterisation of fosfomycin resistance mechanisms and molecular epidemiology in extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates. Characterisation of fosfomycin resistance mechanisms and molecular epidemiology in extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates. |
| 23 | Gan-Lu-Siao-Du-yin, a prescription of traditional Chinese medicine, inhibited enterovirus 71 replication, translation, and virus-induced cell apoptosis Gan-Lu-Siao-Du-yin, a prescription of traditional Chinese medicine, inhibited enterovirus 71 replication, translation, and virus-induced cell apoptosis |
| 24 | 以CArG重複序列作為放射線誘導之分子影像開關 Demonstration of tightly radiation-controlled molecular switch based on CArG repeats by in vivo molecular imaging |
| 25 | 由血管內皮細胞分泌之血管收縮素原為血管重建的重要調節者 Local Augmented Angiotensinogen Secreted from Apoptotic Vascular Endothelial Cells Is a Vital Mediator of Vascular Remodelling |
| 26 | P21-driven multi-fusion gene system for evaluating the efficacy of histone deacetylase inhibitors by in vivo molecular imaging and for transcription targeting therapy of cancer mediated by histone deacetylase inhibitor P21-driven multi-fusion gene system for evaluating the efficacy of histone deacetylase inhibitors by in vivo molecular imaging and for transcription targeting therapy of cancer mediated by histone deacetylase inhibitor |
| 27 | Rational Design of a Triple Reporter Gene for Multimodality Molecular Imaging Rational Design of a Triple Reporter Gene for Multimodality Molecular Imaging |
| 28 | Binding of HIV-1 gp120 to DC-SIGN Promotes ASK-1-Dependent Activation-Induced Apoptosis of Human Dendritic Cells. Binding of HIV-1 gp120 to DC-SIGN Promotes ASK-1-Dependent Activation-Induced Apoptosis of Human Dendritic Cells. |
| 29 | Molecular Imaging of Nonsmall Cell Lung Carcinomas Expressing Active Mutant EGFR Kinase Using PET with [124I]-Morpholino-IPQA Molecular Imaging of Nonsmall Cell Lung Carcinomas Expressing Active Mutant EGFR Kinase Using PET with [124I]-Morpholino-IPQA |
| 30 | The EIIAPA Chimeric Promoter for Tumor Specific Gene Therapy of Hepatoma The EIIAPA Chimeric Promoter for Tumor Specific Gene Therapy of Hepatoma |
| 31 | A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source A Study on the Dose Distributions in Various Materials from an Ir-192 HDR Brachytherapy Source |
| 32 | Specific Activation of Sodium/iodide Symporter Gene in Hepatoma Using Alpha-fetoprotein Promoter Combined with Hepatitis B Virus Enhancer (EIIAPA) Specific Activation of Sodium/iodide Symporter Gene in Hepatoma Using Alpha-fetoprotein Promoter Combined with Hepatitis B Virus Enhancer (EIIAPA) |
Project
| NO |
YEAR — Source — No — Type
Project Name
|
Duration |
|---|---|---|
| 1 |
116 — N 國科會(原科技部) — NSTC114-2314-B-037-089-MY3 — 1 個人型
探討低毒多靶點Flavokawain衍生物透過E2F1調控粒線體功能在口腔癌輻射增敏中的作用及局部遞送劑型開發(3/3)( )
|
2027/08/01 ~ 2028/07/31 |
| 2 |
115 — N 國科會(原科技部) — NSTC114-2314-B-037-089-MY3 — 1 個人型
探討低毒多靶點Flavokawain衍生物透過E2F1調控粒線體功能在口腔癌輻射增敏中的作用及局部遞送劑型開發(2/3)( )
|
2026/08/01 ~ 2028/07/31 |
| 3 |
114 — N 國科會(原科技部) — NSTC114-2314-B-037-089-MY3 — 1 個人型
探討低毒多靶點Flavokawain衍生物透過E2F1調控粒線體功能在口腔癌輻射增敏中的作用及局部遞送劑型開發( )
|
2025/08/01 ~ 2028/07/31 |
| 4 |
113 — N 國科會(原科技部) — NSTC113-2221-E-037-001 — 1 個人型
評估分子對接模擬之RapA1靶向藥物用於口腔鱗狀上皮細胞癌放射治療效果以及開發口腔黏膜藥物遞送系統( )
|
2024/08/01 ~ 2025/07/31 |
| 5 |
113 — Z 大專學生研究計畫及博士後 — NSTC114-2813-C-037-037-B — 8 大專學生研究計畫
114年度大專學生研究計畫-呂晴妍(醫放2)( )
|
2025/07/01 ~ 2026/02/28 |
| 6 |
112 — N 國科會(原科技部) — MOST110-2314-B-037-079-MY3 — 1 個人型
開發具口腔黏膜貼附性之殼聚糖奈米顆粒薄膜於微小RNA口腔癌治療和輻射增敏之應用(3/3)( )
|
2023/08/01 ~ 2024/07/31 |
| 7 |
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-071-B — 8 大專學生研究計畫
113年度大專學生研究計畫-郭子軒(醫放2)( )
|
2024/07/01 ~ 2025/02/28 |
| 8 |
111 — N 國科會(原科技部) — MOST110-2314-B-037-079-MY3 — 1 個人型
開發具口腔黏膜貼附性之殼聚糖奈米顆粒薄膜於微小RNA口腔癌治療和輻射增敏之應用(2/3)( )
|
2022/08/01 ~ 2024/07/31 |
| 9 |
111 — Z 大專學生研究計畫及博士後 — NSTC112-2813-C-037-050-B — 8 大專學生研究計畫
112年度大專學生研究計畫-鍾以庭(醫放2)( )
|
2023/07/01 ~ 2024/02/29 |
| 10 |
110 — N 國科會(原科技部) — MOST110-2314-B-037-079-MY3 — 1 個人型
開發具口腔黏膜貼附性之殼聚糖奈米顆粒薄膜於微小RNA口腔癌治療和輻射增敏之應用(1/3)( )
|
2021/08/01 ~ 2024/07/31 |
| 11 |
109 — A 原委會 — NL1100431 —
110年度gamma-H2AX免疫螢光染色分析及染色體雙中節分析勞務案( )
|
2021/05/19 ~ 2021/10/29 |
| 12 |
109 — N 國科會(原科技部) — MOST109-2314-B-037-032 — 1 個人型
發展並探討經口腔黏膜運送之殼聚糖奈米載體裝載miR-30c-5p在口腔癌的抗癌及輻射增敏效果( )
|
2020/08/01 ~ 2021/09/30 |
| 13 |
109 — Z 大專學生研究計畫及博士後 — MOST110-2813-C-037-026-B — 8 大專學生研究計畫
110年度大專學生研究計畫-丁靚(醫放2)( )
|
2021/07/01 ~ 2022/02/28 |
| 14 |
109 — Z 大專學生研究計畫及博士後 — MOST110-2813-C-037-027-B — 8 大專學生研究計畫
110年度大專學生研究計畫-劉芝岑(醫放2)( )
|
2021/07/01 ~ 2022/02/28 |
| 15 |
108 — A 原委會 — NL1090583 —
109年度gamma-H2AX分析研究及染色體雙中節分析勞務案( )
|
2020/06/23 ~ 2020/10/31 |
| 16 |
108 — N 國科會(原科技部) — MOST108-2314-B-037-023 — 1 個人型
GSKIP藉由調控粒線體動態與腫瘤幹細胞以促進口腔癌輻射抗性之角色探討( )
|
2019/08/01 ~ 2020/10/31 |
| 17 |
107 — N 國科會(原科技部) — MOST107-2314-B-037-049 — 1 個人型
探討Fli-1於口腔鱗狀上皮細胞癌輻射抗性之角色以及蛋白質乙醯化作用對Fli-1所調節之輻射抗性影響( )
|
2018/08/01 ~ 2019/07/31 |
| 18 |
106 — N 國科會(原科技部) — MOST106-2314-B-037-020 — 1 個人型
探討在口腔鱗狀上皮細胞癌內GSKIP和Wntless對Wnt/beta-catenin路徑所調控之放射敏感度的影響:臨床病理結果之潛力預測因子( )
|
2017/08/01 ~ 2018/07/31 |
| 19 |
105 — N 國科會(原科技部) — MOST104-2314-B-037-055-MY2 — 1 個人型
開發具蛋白酶依賴性造影探針以偵測和追蹤日本腦炎病毒(JEV)在活體分佈情形(2/2)( )
|
2016/08/01 ~ 2017/07/31 |
| 20 |
105 — TP 頂尖計畫(高醫) — KMU-TP105PR11 —
探討口腔癌細胞照射後之自噬作用角色( )
|
2017/02/01 ~ 2017/10/31 |
| 21 |
104 — N 國科會(原科技部) — MOST104-2314-B-037-055-MY2 — 1 個人型
開發具蛋白酶依賴性造影探針以偵測和追蹤日本腦炎病毒(JEV)在活體分佈情形(1/2)( )
|
2015/08/01 ~ 2017/07/31 |
| 22 |
104 — TP 頂尖計畫(高醫) — KMU-TP104PR29 —
以動物模式驗證蛋白酶依賴性造影探針以偵測和追蹤日本腦炎病毒(JEV)在活體分佈情形( )
|
2016/05/01 ~ 2016/09/30 |
| 23 |
104 — Z 大專學生研究計畫及博士後 — MOST105-2815-C-037-030-B — 8 大專學生研究計畫
105年度大專學生研究計畫-劉杉珊(生物2)( )
|
2016/07/01 ~ 2017/02/28 |
| 24 |
103 — N 國科會(原科技部) — MOST103-2314-B-037-007 — 1 個人型
開發具蛋白酶依賴性造影探針以偵測和追蹤黃病毒(HCV/JEV)在活體分佈情形( )
|
2014/08/01 ~ 2015/07/31 |
| 25 |
102 — Z 大專學生研究計畫及博士後 — 103-2815-C-037-027-B — 8 大專學生研究計畫
103年度大專學生研究計畫-張馥讌(醫放2)( )
|
2014/07/01 ~ 2015/02/28 |
| 26 |
099 — Q 新聘教師計畫(校內) — Q100018 —
活體內腫瘤幹細胞之示蹤與分離( )
|
2011/01/01 ~ 2011/12/31 |
| 27 |
098 — Q 新聘教師計畫(校內) — KMU-Q099026 —
以噬菌體表達技術篩選出對不同somatostatin接受器具選擇性結合的單鏈抗體( )
|
2010/02/01 ~ 2010/12/31 |