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 Education

School — Major — Degree Duration

國立成功大學 — 基礎醫學研究所(畢) — 博士

Doctorate, Institute of Basic Medical Sciences, National Cheng Kung University

2000/09 — 2006/01

國立中興大學 — 分子生物學研究所(畢) — 碩士

Master, Institute of molecular biology, National Chung Hsing University

1993/09 — 1996/06

東海大學 — 生物學系(畢) — 學士

Bachelor, Department of life science, Tunghai University

1989/09 — 1993/06

 Intramural Experience

Office/Department/Institute Position Duration
醫學研究所 Graduate Institute of Medicine   Professor 2019/08/01 —  
醫學研究所 Graduate Institute of Medicine   Associate Professor 2015/08/01 — 2019/07/31
生理學科 Department of Physiology   Associate Professor 2012/08/01 — 2015/07/31
生理學科 Department of Physiology   Assistant Professor 2007/08/01 — 2012/07/31

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 生理 Physiology
2 生物醫農類 Biology, Medicine and Agriculture 醫學之生化及分子生物 Medical Biochemistry and Molecular Biology
3 生物醫農類 Biology, Medicine and Agriculture 腎臟科、新陳代謝及內分泌 Division of Nephrology, Division of Metabolism & Endocrinology
4 生物醫農類 Biology, Medicine and Agriculture 骨科 Division of Orthopedics

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

生理,物理治療、醫化、生醫、藥理,,DDR1研究

 

 Area(s) of Expertise & Research

DDR1接受器研究、硬骨與軟骨相關疾病與天然藥物治療研究、幹細胞與醫材結合之再生醫學研究、collagen receptor之訊息傳遞機制研究、Phyical stimulation on myotube and tendon regeneration study

DDR1 receptor research, bone and cartilage related diseases and natural medicine treatment research, regenerative medicine research combining stem cells and medical materials, collagen receptor message transmission mechanism research, Phyical stimulation on myotube and tendon regeneration study

 Publication

NO Publication
1

Adipose derived stem cells loaded photocurable and bioprintable bioinks composed of GelMA, HAMA and PEGDA crosslinker to differentiate into smooth muscle phenotype.
Pavanchandh Atturu, Sunaina Mudigonda, 王昭仁, 吳順成, 陳振偉, Mary Fornica Francis Forgia, 譚漢詩, 王志光* - - 1 - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2024 265卷(2期):130710頁
(IF: 8.2, 領域排名: 5, 領域期刊數: 86, 領域排名: 5.81%)

Adipose derived stem cells loaded photocurable and bioprintable bioinks composed of GelMA, HAMA and PEGDA crosslinker to differentiate into smooth muscle phenotype.
Pavanchandh Atturu, Sunaina Mudigonda, Chau-Zen Wang, Shun-Cheng Wu, Jhen-Wei Chen, Mary Fornica Francis Forgia, Hans-Uwe Dahms, Chih-Kuang Wang - - 1 - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2024;265(2):130710
(IF: 8.2, Journal Ranking: 5, Number of Journals of this Field: 86, Ranking: 5.81%)

2

軟骨細胞之凝血酶調節素可對抗骨關節炎
Lin Kang, Ai-Lun Yang#, Chao-Han Lai, 陳贊如, 林松彥, 王彥雄, 王昭仁, Edward M Conway, Hua-Lin Wu, 何美泠, 張瑞根, 陳崇桓*, 鄭琮霖* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 24卷(11期):9522頁
(IF: 5.6, 領域排名: 66, 領域期刊數: 285, 領域排名: 23.16%)

Chondrocyte Thrombomodulin Protects against Osteoarthritis.
Lin Kang, Ai-Lun Yang#, Chao-Han Lai, Tsan-Ju Chen, Sung-Yen Lin, Yan-Hsiung Wang, Chau-Zen Wang, Edward M Conway, Hua-Lin Wu, Mei-Ling Ho, Je-Ken Chang, Chung-Hwan Chen*, Tsung-Lin Cheng* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023;24(11):9522
(IF: 5.6, Journal Ranking: 66, Number of Journals of this Field: 285, Ranking: 23.16%)

3

Exploring the cellular and molecular mechanism of discoidin domain receptors (DDR1 and DDR2) in bone formation, regeneration, and its associated disease conditions.
Arokia Vijaya Anand Mariadoss,王昭仁* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 24卷(19期):14895頁
(IF: 5.6, 領域排名: 66, 領域期刊數: 285, 領域排名: 23.16%)

Exploring the cellular and molecular mechanism of discoidin domain receptors (DDR1 and DDR2) in bone formation, regeneration, and its associated disease conditions.
Arokia Vijaya Anand Mariadoss and Chau-Zen Wang* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023;24(19):14895
(IF: 5.6, Journal Ranking: 66, Number of Journals of this Field: 285, Ranking: 23.16%)

4

Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis
周心喬 ,林松彥#, 周亮吟, 何美泠, 莊淑君, 鄭琮霖, 康琳, 林怡珊, 王彥雄, 魏春旺, 陳崇桓*, 王昭仁* - - 1 - BIOMEDICINES - BIOMEDICINES 2022 10卷(9期):2173頁
(IF: 4.757, 領域排名: 121, 領域期刊數: 297, 領域排名: 40.74%)

Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis
Hsin-Chiao Chou, Sung-Yen Lin†, Liang-Yin Chou, Mei-Ling Ho, Shu-Chun Chuang, Tsung-Lin Cheng, Lin Kang, Yi-Shan Lin, Yan-Hsiung Wang, Chun-Wang Wei, Chung-Hwan Chen* and Chau-Zen Wang* - - 1 - BIOMEDICINES - BIOMEDICINES 2022;10(9):2173
(IF: 4.757, Journal Ranking: 121, Number of Journals of this Field: 297, Ranking: 40.74%)

5

The Essential Role of Stathmin in Myoblast C2C12 for Vertical Vibration-Induced Myotube Formation.
林逸翔, Liang-Yin Chou#, Hsin-Chiao Chou, 陳崇桓, Lin Kang, 鄭琮霖, 王昭仁* - - 1 - BIOMOLECULES - BIOMOLECULES 2021 11卷(11期):1583頁
(IF: 6.064, 領域排名: 75, 領域期刊數: 296, 領域排名: 25.34%)

The Essential Role of Stathmin in Myoblast C2C12 for Vertical Vibration-Induced Myotube Formation.
Yi-Hsiung Lin, Liang-Yin Chou, Hsin-Chiao Chou, Chung-Hwan Chen, Lin Kang, Tsung-Lin Cheng, Chau-Zen Wang - - 1 - BIOMOLECULES - BIOMOLECULES 2021;11(11):1583
(IF: 6.064, Journal Ranking: 75, Number of Journals of this Field: 296, Ranking: 25.34%)

6

Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes
周亮吟, 陳崇桓#, 林益祥, 莊淑君, 周心喬, 林松彥, 傅尹志, 張瑞根, 何美泠*, 王昭仁* - - 1 - FASEB JOURNAL - FASEB JOURNAL 2020 34卷(4期):5767-5781頁
(IF: 5.191, 領域排名: 14, 領域期刊數: 93, 領域排名: 15.05%)

Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes
Liang‐Yin Chou, Chung‐Hwan Chen#, Yi‐Hsiung Lin, Shu‐Chun Chuang, Hsin‐Chiao Chou, Sung‐Yen Lin, Yin‐Chi Fu, Je‐Ken Chang, Mei‐Ling Ho*, Chau‐Zen Wang* - - 1 - FASEB JOURNAL - FASEB JOURNAL 2020;34(4):5767-5781
(IF: 5.191, Journal Ranking: 14, Number of Journals of this Field: 93, Ranking: 15.05%)

7

Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
周心喬, 陳崇桓, 周亮吟, 鄭琮霖, 康琳, 莊淑君, 林怡珊, 何美泠, 王彥雄, 林松彥*, 王昭仁* - - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21卷(19期):6991頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
Hsin-Chaio Chou, Chung-Hwan Chen, Liang-Yin Chou, Tsung-Lin Cheng, Lin Kang, Shu-Chun Chuang, Yi-Shan Lin, Mei-Ling Ho, Yan-Hsiung Wang, Sung-Yen Lin*, Chau-Zen Wang* - - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(19):6991
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

8

Discoidin domain receptor 1 regulates Runx2 during osteogenesis of osteoblasts and promotes bone ossification via phosphorylation of p-38.
周亮吟, 陳崇桓, 莊淑君, 鄭琮霖, 林逸翔, 周心喬, 傅尹志, 王彥雄, 王昭仁* - - 1 - International Journal of Molecular Sciences. - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21卷(19期):7210頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Discoidin domain receptor 1 regulates Runx2 during osteogenesis of osteoblasts and promotes bone ossification via phosphorylation of p-38.
Liang-Yin Chou, Chung-Hwan Chen, Shu-Chun Chuang, Tsung-Lin Cheng, Yi-Hsiung Lin, Hsin-Chiao Chou, Yin-Chih Fu, Yan-Hsiung Wang, Chau-Zen Wang*. - - 1 - International Journal of Molecular Sciences. - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(19):7210
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

9

(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
林松彥, 康琳, 陳建志, 王昭仁, 黃炫迪, 李孟娟, 鄭琮霖, 張綺芬, 林怡珊, 陳崇桓* - - 1 - Phytomedicine - PHYTOMEDICINE 2019 55卷(-期):165-171頁
(IF: 4.18, 領域排名: 1, 領域期刊數: 27, 領域排名: 3.70%)

(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
Lin SY, Kang L, Chen JC, Wang CZ, Huang HH, Lee MJ, Cheng TL, Chang CF, Lin YS, Chen CH* - - 1 - Phytomedicine - PHYTOMEDICINE 2019;55(-):165-171
(IF: 4.18, Journal Ranking: 1, Number of Journals of this Field: 27, Ranking: 3.70%)

10

(-)-Epigallocatechin-3-Gallate Decrease Osteoclastogenesis via Modulation of RANKL and Osteoprotegrin
Chen ST,康琳,王昭仁, 黃鵬如,黃炫迪,林松彥,周世祥,盧政 昌,沈柏志,林怡珊,陳崇桓 * - - 1 - Molecules - MACROMOLECULES 2019 24卷(1期):156頁
(IF: 5.997, 領域排名: 5, 領域期刊數: 87, 領域排名: 5.75%)

(-)-Epigallocatechin-3-Gallate Decrease Osteoclastogenesis via Modulation of RANKL and Osteoprotegrin
Chen ST, Kang L, Wang CZ, Huang PJ, Huang HT, Lin SY, Chou SH, Lu CC, Shen PC, Lin YS, Chen CH *. - - 1 - Molecules - MACROMOLECULES 2019;24(1):156
(IF: 5.997, Journal Ranking: 5, Number of Journals of this Field: 87, Ranking: 5.75%)

11

Alpha-5 Integrin Mediates Simvastatin-Induced Osteogenesis of Bone Marrow Mesenchymal Stem Cells
紹佩玲, 吳順成, 林子尹, 何美泠, 陳崇桓, 王昭仁* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019 20卷(3期):506頁
(IF: 4.556, 領域排名: 74, 領域期刊數: 297, 領域排名: 24.92%)

Alpha-5 Integrin Mediates Simvastatin-Induced Osteogenesis of Bone Marrow Mesenchymal Stem Cells
Pei-Lin Shao, Shun-Cheng Wu, Zih-Yin Lin, Mei-Ling Ho, Chung-Hwan Chen, Chau-Zen Wang* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019;20(3):506
(IF: 4.556, Journal Ranking: 74, Number of Journals of this Field: 297, Ranking: 24.92%)

12

Enhancement of chondrogenesis of adipose-derived stem cells in HA-PNIPAAm-CL hydrogel for cartilage regeneration in rabbits.
王昭仁,陳崇桓,傅尹志,王志光,張瑞根*,何美泠* - - 1 - Scientific Reports - SCIENTIFIC REPORTS 2018 8卷(0期):10526頁
(IF: 4.122, 領域排名: 12, 領域期刊數: 64, 領域排名: 18.75%)

Enhancement of chondrogenesis of adipose-derived stem cells in HA-PNIPAAm-CL hydrogel for cartilage regeneration in rabbits.
Chau-Zen Wang; Rajalakshmanan Eswaramoorthy; Tzu-Hsiang Lin; Chung-Hwan Chen; Yin-Chih Fu; Chih-Kuang Wang; Shun-Cheng Wu; Gwo-Jaw Wang; Je-Ken Chang#*; Mei-Ling Ho#* - - 1 - Scientific Reports - SCIENTIFIC REPORTS 2018;8(0):10526
(IF: 4.122, Journal Ranking: 12, Number of Journals of this Field: 64, Ranking: 18.75%)

13

Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon.
陳嘉炘,林怡伶,陳崇桓,王彥雄,葉明龍,鄭琮霖,王昭仁* - - 1 - PLoS One - PLOS ONE 2018 13卷(10期):e0205258.頁
(IF: 2.766, 領域排名: 15, 領域期刊數: 64, 領域排名: 23.44%)

Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon.
Chen CH, Lin YH, Chen CH, Wang YH, Yeh ML, Cheng TL, Wang CZ*. - - 1 - PLoS One - PLOS ONE 2018;13(10):e0205258.
(IF: 2.766, Journal Ranking: 15, Number of Journals of this Field: 64, Ranking: 23.44%)

14

(-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
林松彥,康琳,王昭仁,黃漢翔,鄭琮霖, 黃炫迪,李孟娟,林怡珊,何美泠,王國照, 陳崇桓 * - - 1 - Molecules - MOLECULES 2018 23,卷(1期):3221頁
(IF: 3.098, 領域排名: 68, 領域期刊數: 170, 領域排名: 40.00%)

(-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Lin SY, Kang L, Wang CZ, Huang HH, Cheng TL, Huang HT, Lee MJ, Lin YS, Ho ML, Wang GJ, Chen CH * - - 1 - Molecules - MOLECULES 2018;23,(1):3221
(IF: 3.098, Journal Ranking: 68, Number of Journals of this Field: 170, Ranking: 40.00%)

15

Combination of a bioceramic scaffold and simvastatin nanoparticles as a synthetic alternative to autologous bone grafting
王昭仁, 王彥雄, 林哲緯, 李天慶, 傅尹志, 何美泠, 王志光* - - 1 - Int J Mol Sci. - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018 19卷(12期):E4099頁
(IF: 3.687, 領域排名: 52, 領域期刊數: 170, 領域排名: 30.59%)

Combination of a bioceramic scaffold and simvastatin nanoparticles as a synthetic alternative to autologous bone grafting
Chau-Zen Wang, Yan-Hsiung Wang, Che-Wei Lin, Tien-Ching Lee, Yin-Chih Fu, Mei-Ling Ho, Chih-Kuang Wang* - - 1 - Int J Mol Sci. - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018;19(12):E4099
(IF: 3.687, Journal Ranking: 52, Number of Journals of this Field: 170, Ranking: 30.59%)

16

Enhancement of Bone Marrow-Derived Mesenchymal Stem Cell Osteogenesis and New Bone Formation in Rats by Obtusilactone A
Yi-Hsiung Lin,Chung-Yi Chen,Liang-Yin Chou,陳崇桓,康琳,王昭仁* - - 1 - International Journal of Molecular Sciences - INT J MOL SCI 2017 18卷(11期):E2422頁
(IF: 3.226, 領域排名: 54, 領域期刊數: 165, 領域排名: 32.73%)

Enhancement of Bone Marrow-Derived Mesenchymal Stem Cell Osteogenesis and New Bone Formation in Rats by Obtusilactone A
Yi-Hsiung Lin,Chung-Yi Chen,Liang-Yin Chou,Chung-Hwan Chen, Lin Kang,Chau-Zen Wang* - - 1 - International Journal of Molecular Sciences - INT J MOL SCI 2017;18(11):E2422
(IF: 3.226, Journal Ranking: 54, Number of Journals of this Field: 165, Ranking: 32.73%)

17

髓系凝血酶調節素類凝集素功能區抑制食骨細胞生成作用與發炎性骨質流失
鄭琮霖, 賴昭翰, 謝式洲, 周吟柏, 葉竹來, 楊艾倫, 王彥雄, 王昭仁, 陳崇桓, 施桂月, 何美泠*, 吳華林* - - 1 - Scientific Reports - SCI REP-UK 2016 ?6卷(-期):28340頁
(IF: 5.228, 領域排名: 7, 領域期刊數: 63, 領域排名: 11.11%)

Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss
Tsung-Lin Cheng, Chao-Han Lai, Shyh-Jou Shieh, Yin-Bo Jou, Jwu-Lai Yeh, Ai-Lun Yang, Yan-Hsiung Wang, Chau-Zen Wang, Chung-Hwan Chen, Guey-Yueh Shi, Mei-Ling Ho*, Hua-Lin Wu* - - 1 - Scientific Reports - SCI REP-UK 2016;?6(-):28340
(IF: 5.228, Journal Ranking: 7, Number of Journals of this Field: 63, Ranking: 11.11%)

18

Suppression of discoidin domain receptor 1 expression enhances the chondrogenesis of adipose-derived stem cells
吳順成, Hsu-Feng Hsiao, 何美泠, Yung-Li Hung, 張瑞根, 王國照,王昭仁* - - 1 - AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY - AM J PHYSIOL-CELL PH 2015 308卷(9期):C685-C696頁
(IF: 3.78, 領域排名: 19, 領域期刊數: 83, 領域排名: 22.89%)

Suppression of discoidin domain receptor 1 expression enhances the chondrogenesis of adipose-derived stem cells
Shun-Cheng Wu, Hsu-Feng Hsiao, Mei-Ling Ho, Yung-Li Hung, Je-Ken Chang, Gwo-Jaw Wang, Chau-Zen Wang* - - 1 - AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY - AM J PHYSIOL-CELL PH 2015;308(9):C685-C696
(IF: 3.78, Journal Ranking: 19, Number of Journals of this Field: 83, Ranking: 22.89%)

19

低能量雷射治療於背根神經節壓迫之效益
陳怡媜,王彥雄,王昭仁,何美泠,郭柏麟,黃茂雄,陳嘉炘* - - 1 - Plos One - Plos One 2014 9卷(3期):e89894(1-8)頁
(IF: 3.534, 領域排名: 8, 領域期刊數: 55, 領域排名: 14.55%)

Effect of low level laser therapy on chronic compression of the dorsal root ganglion
Yi-Jen Chen, Yan-Hsiung Wang, Chau-Zen Wang, Mei-Ling Ho, Po-Lin Kuo, Mao-Hsiung Huang, Chia-Hsin Chen - - 1 - Plos One - Plos One 2014;9(3):e89894(1-8)
(IF: 3.534, Journal Ranking: 8, Number of Journals of this Field: 55, Ranking: 14.55%)

20

合成陽離子高分子奈米粒子為simvastatin藥物載體對其促進骨髓間質幹細胞成骨化之特性研究
王昭仁, 傅尹志(共同第一), 簡士強, 王彥雄, 劉博侖, 何美泠,王志光* - - 1 - JOURNAL OF COLLOID AND INTERFACE SCIENCE - J COLLOID INTERF SCI 2014 432卷(-期):190-199頁
(IF: 3.552, 領域排名: 38, 領域期刊數: 136, 領域排名: 27.94%)

Synthesis and characterization of cationic polymeric nanoparticles as simvastatin carriers for enhancing the osteogenesis of bone marrow mesenchymal stem cells
Chau-Zen Wang, Yin-Chih Fu, Yan-Hsiung Wang, Po-Len Liu, Shih-Ciang Jian, Mei-Ling Ho, Chih-Kuang Wang* - - 1 - JOURNAL OF COLLOID AND INTERFACE SCIENCE - J COLLOID INTERF SCI 2014;432(-):190-199
(IF: 3.552, Journal Ranking: 38, Number of Journals of this Field: 136, Ranking: 27.94%)

21

低能量雷射治療改善坐骨神經壓迫損傷後之功能回復與神經再生
王昭仁,陳怡媜, 王彥雄,黃茂雄,何美泠, 陳嘉炘* - - 1 - PLOS ONE - Plos One 2014 9卷(8期):e103348(1-11)頁
(IF: 3.534, 領域排名: 8, 領域期刊數: 55, 領域排名: 14.55%)

Low-level laser irradiation improves functional recovery and nerve regeneration in sciatic nerve crush rat injury model
Chau-Zen Wang, Yi-Jen Chen,Yan-Hsiung Wang, Ming-Long Yeh, Mao-Hsiung Huang, Mei-Ling Ho ,Jen-I Liang and Chia-Hsin Chen* - - 1 - PLOS ONE - Plos One 2014;9(8):e103348(1-11)
(IF: 3.534, Journal Ranking: 8, Number of Journals of this Field: 55, Ranking: 14.55%)

22

低能雷射經由表觀基因對單核球第一型巨噬細胞相關細胞激素表達之影響
陳嘉炘,王昭仁,廖偉廷,郭昶宏,郭炫孚,洪志興* - - 1 - MEDIATORS OF INFLAMMATION - MEDIAT INFLAMM 2014 2014卷(-期):625048(1-13)頁
(IF: 2.417, 領域排名: 89, 領域期刊數: 144, 領域排名: 61.81%)

Effects of low-level laser therapy on M1-related cytokine expression in monocytes via histone modification
Chen CH, Wang CZ, Wang YH, Liao WT, Chen YJ, Kuo CH, Kuo HF, Hung CH* - - 1 - MEDIATORS OF INFLAMMATION - MEDIAT INFLAMM 2014;2014(-):625048(1-13)
(IF: 2.417, Journal Ranking: 89, Number of Journals of this Field: 144, Ranking: 61.81%)

23

人類脂肪幹細胞在支架無懸浮培養生長分化能力的表徵和評估
王彥雄,吳俊毅(共同第一),周佩蓉,陳崇桓,王昭仁,何美泠,張瑞根,陳嘉炘* - - 1 - Cytotherapy - Cytotherapy 2014 16卷(4期):485-495頁
(IF: 3.1, 領域排名: 45, 領域期刊數: 165, 領域排名: 27.27%)

Characterization and evaluation of the differentiation ability of human adipose-derived stem cells growing in scaffold-free suspension culture.
Wang YH, Wu JY, Chou PJ, Chen CH, Wang CZ, Ho ML, Chang JK, Yeh ML, Chen CH* - - 1 - Cytotherapy - Cytotherapy 2014;16(4):485-495
(IF: 3.1, Journal Ranking: 45, Number of Journals of this Field: 165, Ranking: 27.27%)

24

Effects of Low-Level Laser Therapy on M1-Related Cytokine Expression in Monocytes via Histone Modification
陳嘉炘, 王昭仁, 王彥雄, - - 0 - Mediators of Inflammation - 2014 2014卷(2014期):ID625048頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

Effects of Low-Level Laser Therapy on M1-Related Cytokine Expression in Monocytes via Histone Modification
Chia-Hsin Chen, Chau-Zen Wang,Yan-Hsiung Wang, Wei-Ting Liao, Yi-Jen Chen, Chang-Hung Kuo, Hsuan-Fu Kuo, and Chih-Hsing Hung - - 0 - Mediators of Inflammation - 2014;2014(2014):ID625048
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

25

Electromagnetic fields enhance chondrogenesis of human adipose-derived stem cells in a chondrogenic microenvironment in vitro.
陳崇桓,林怡珊,傅尹志,王志光,吳順成,王國照,路卡曼,王彥雄,王昭仁,王耀賢,林松彥,張瑞根*,何美泠* - - 1 - JOURNAL OF APPLIED PHYSIOLOGY - J APPL PHYSIOL 2013 114卷(5期):647-655頁
(IF: 3.484, 領域排名: 20, 領域期刊數: 80, 領域排名: 25.00%)

Electromagnetic fields enhance chondrogenesis of human adipose-derived stem cells in a chondrogenic microenvironment in vitro.
Chung-Hwan Chen, Yi-Shan Lin, Yin-Chih Fu, Chih-Kuang Wang, Shun-Cheng Wu, Gwo-Jaw Wang, Rajalakshmanan Eswaramoorthy, Yan-Hsiung Wang, Chau-Zen Wang, Yao-Hsien Wang, Sung-Yen Lin, Je-Ken Chang, Mei-Ling Ho* - - 1 - JOURNAL OF APPLIED PHYSIOLOGY - J APPL PHYSIOL 2013;114(5):647-655
(IF: 3.484, Journal Ranking: 20, Number of Journals of this Field: 80, Ranking: 25.00%)

26

負溫感水膠製備多孔性生物陶瓷結合控制釋放rhBMP-2載體:體外與體內研究
傅尹志,陳崇桓,王昭仁,王彥雄,張瑞根,王國照,何美泠*,王志光* - - 1 - Journal of the Mechanical Behavior of Biomedical Materials - J MECH BEHAV BIOMED 2013 27卷(-期):64-76頁
(IF: 2.368, 領域排名: 25, 領域期刊數: 79, 領域排名: 31.65%)

Preparation of Porous Bioceramics Using Reverse Thermo-Responsive Hydrogels in Combination with rhBMP-2 Carriers: In Vitro and In Vivo Evaluation
Yin-Chih Fu, Chung-Hwan Chen, Chau-Zen Wang, Yan-Hsiung Wang, Je-Ken Chang, Gwo-Jaw Wang, Mei-Ling Ho*, Chih-Kuang Wang* - - 1 - Journal of the Mechanical Behavior of Biomedical Materials - J MECH BEHAV BIOMED 2013;27(-):64-76
(IF: 2.368, Journal Ranking: 25, Number of Journals of this Field: 79, Ranking: 31.65%)

27

四級胺鹽官能基分子修飾 PLGA-PEG高分子成陽離子奈米粒子在基因轉殖研究
王彥雄,傅尹志,邱惠琪,王昭仁,羅紹萍,何美泠,劉博侖,王志光* - - 1 - JOURNAL OF NANOPARTICLE RESEARCH - J NANOPART RES 2013 15卷(11期):2077--2092頁
(IF: 2.175, 領域排名: 57, 領域期刊數: 241, 領域排名: 23.65%)

Cationic nanoparticles with quaternary ammonium functionalized PLGA-PEG-based copolymers for potent gene transfection
Yan-Hsung Wang, Yin-Chih Fu, Hui-Chi Chiu, Chau-Zen Wang, Shao-Ping Lo, Mei-Lin Ho, Po-Len Liu, Chih-Kuang Wang - - 1 - JOURNAL OF NANOPARTICLE RESEARCH - J NANOPART RES 2013;15(11):2077--2092
(IF: 2.175, Journal Ranking: 57, Number of Journals of this Field: 241, Ranking: 23.65%)

28

低能量雷射照射促進幹細胞經由IGF1 and BMP 造成骨化
吳俊毅,王彥雄(共同第一), 王國照, 何美泠, 王昭仁,葉明龍(成大)*, 陳嘉炘* - - 1 - PLoS One - PLOS ONE 2012 7卷(9期):e44027頁
(IF: 4.092, 領域排名: 12, 領域期刊數: 85, 領域排名: 14.12%)

Low-Power GaAlAs Laser Irradiation Promotes the Proliferation and Osteogenic Differentiation of Stem Cells via IGF1 and BMP2.
Jyun-Yi Wu, Yan-Hsiung Wang, Gwo-Jaw Wang, Mei-Ling Ho, Chau-Zen Wang, Ming-Long Yeh,, Chia-Hsin Chen - - 1 - PLoS One - PLOS ONE 2012;7(9):e44027
(IF: 4.092, Journal Ranking: 12, Number of Journals of this Field: 85, Ranking: 14.12%)

29

Characterization and enhancement of chondrogenesis in porous hyaluronic acid-modified scaffolds made of PLGA(75/25) blended with PEI-grafted PLGA(50/50).
王昭仁, 何美泠, 陳文正, 邱建智, 洪永豊, 王志光*, 吳順成 - - 1 - Materials Science and Engineering C -Mater. Biol. - MAT SCI ENG C-MATER 2011 31卷(7期):1343-1351頁
(IF: 2.178, 領域排名: 15, 領域期刊數: 25, 領域排名: 60.00%)

Characterization and enhancement of chondrogenesis in porous hyaluronic acid-modified scaffolds made of PLGA(75/25) blended with PEI-grafted PLGA(50/50).
Chau-Zen Wang, Mei-Ling Ho, Wen-Cheng Chen, Chien-Chih Chiu, Yung-Li Hung, Chih-Kuang Wang*, Shun-Cheng Wu. - - 1 - Materials Science and Engineering C -Mater. Biol. - MAT SCI ENG C-MATER 2011;31(7):1343-1351
(IF: 2.178, Journal Ranking: 15, Number of Journals of this Field: 25, Ranking: 60.00%)

30

The effect of the local delivery of alendronate on human adipose-derived stem cell-based bone regeneration
王昭仁,陳世茂,陳崇桓,王國照,張瑞根,何美泠* - - 1 - Biomaterials. 2010 - BIOMATERIALS 2011 33卷(31期):8674-8683頁
(IF: 7.882, 領域排名: 2, 領域期刊數: 69, 領域排名: 2.90%)

The effect of the local delivery of alendronate on human adipose-derived stem cell-based bone regeneration
Wang CZ, Chen SM, Chen CH, Wang CK, Wang GJ, Chang JK, Ho ML. - - 1 - Biomaterials. 2010 - BIOMATERIALS 2011;33(31):8674-8683
(IF: 7.882, Journal Ranking: 2, Number of Journals of this Field: 69, Ranking: 2.90%)

31

Contributions of active site residues to cofactor binding and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase.
王昭仁(Co-first) - - 1 - BBA-PROTEINS PROTEOM - BBA-PROTEINS PROTEOM 2010 1804卷(1期):235-241頁
(IF: 2.773, 領域排名: 36, 領域期刊數: 73, 領域排名: 49.32%)

Contributions of active site residues to cofactor binding and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase.
Yi-Hsun Chang, Chau-Zen Wang(Co-first), Chien-Chih Chiu, Lea-Yea Chuang, Chi-Ching Hwang. - - 1 - BBA-PROTEINS PROTEOM - BBA-PROTEINS PROTEOM 2010;1804(1):235-241
(IF: 2.773, Journal Ranking: 36, Number of Journals of this Field: 73, Ranking: 49.32%)

32

Preparation and Characterization of Calcium Phosphate Deposited on Gold Nanoparticles
王志光,王昭仁,王震乾,洪純正,利宛芸,陳文正* - - 1 - J NON-CRYST SOLIDS - J NON-CRYST SOLIDS 2010 356卷(18-19期):927-932頁
(IF: 1.483, 領域排名: 4, 領域期刊數: 25, 領域排名: 16.00%)

Preparation and Characterization of Calcium Phosphate Deposited on Gold Nanoparticles
Chih-Kuang Wang, Chau-Zen Wang, Jen-Chyan Wang, Chun-Cheng Hung, Wan-Yun Li, Wen-Cheng Chen* - - 1 - J NON-CRYST SOLIDS - J NON-CRYST SOLIDS 2010;356(18-19):927-932
(IF: 1.483, Journal Ranking: 4, Number of Journals of this Field: 25, Ranking: 16.00%)

33

DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation.
王昭仁,王志光,陳文正,湯明哲,何美泠,黃啟清,王惠民,王昭仁* - - 1 - J Cell Physiol. - J CELL PHYSIOL 2010 224卷(2期):387-397頁
(IF: 3.986, 領域排名: 13, 領域期刊數: 77, 領域排名: 16.88%)

DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation.
Eswa R, C.K. Wang, W.C. Chen, M.J. Tang, M.L. Ho, C.C. Hwang, H.M. Wang and Chau-Zen Wang*. - - 1 - J Cell Physiol. - J CELL PHYSIOL 2010;224(2):387-397
(IF: 3.986, Journal Ranking: 13, Number of Journals of this Field: 77, Ranking: 16.88%)

34

低振幅垂直振動促進肌母細胞肌束形成
王昭仁,王國照,何美泠,王彥雄,葉明龍,陳嘉炘* - - 1 - J Appl Physiol - J APPL PHYSIOL 2010 109卷(3期):840-848頁
(IF: 4.232, 領域排名: 2, 領域期刊數: 79, 領域排名: 2.53%)

Low-magnitude vertical vibration enhances myotube formation in C2C12 myoblasts.
Wang CZ,Wang GJ,Ho ML,Wang YH,Yeh ML,Chen CH - - 1 - J Appl Physiol - J APPL PHYSIOL 2010;109(3):840-848
(IF: 4.232, Journal Ranking: 2, Number of Journals of this Field: 79, Ranking: 2.53%)

35

(-)-N-Formylanonaine from Michelia alba as human tyrosinase inhibitor and antioxidant
王惠民*, 王昭仁 - - 1 - Bioorganic & Medicinal Chemistry - BIOORGAN MED CHEM 2010 18卷(14期):5241-5247頁
(IF: 2.978, 領域排名: 16, 領域期刊數: 56, 領域排名: 28.57%)

(-)-N-Formylanonaine from Michelia alba as human tyrosinase inhibitor and antioxidant
Hui-Min Wang*, Chung-Yi Chen, Chun-Yen Chen, Mei-Ling Ho, Yi-Ting Chou, Hou-Chien Chang, Chih-Hung Lee, Chau-Zen Wang, I-Ming Chu. - - 1 - Bioorganic & Medicinal Chemistry - BIOORGAN MED CHEM 2010;18(14):5241-5247
(IF: 2.978, Journal Ranking: 16, Number of Journals of this Field: 56, Ranking: 28.57%)

36

The effect of the local delivery of alendronate on human adipose-derived stem cell-based bone regeneration
王昭仁, Chen, SM (Chen, Shih-Mao), 陳崇桓, 王志光, 王國照, 張瑞根*, 何美泠* - - 1 - Biomaterials - BIOMATERIALS 2010 31卷(33期):8674-8683頁
(IF: 7.882, 領域排名: 2, 領域期刊數: 25, 領域排名: 8.00%)

The effect of the local delivery of alendronate on human adipose-derived stem cell-based bone regeneration
Wang, CZ (Wang, Chau-Zen), Chen, SM (Chen, Shih-Mao), Chen, CH (Chen, Chung-Hwan), Wang, CK (Wang, Chih-Kuang), Wang, GJ (Wang, Gwo-Jaw), Chang, JK (Chang, Je-Ken), Ho, ML (Ho, Mei-Ling)* - - 1 - Biomaterials - BIOMATERIALS 2010;31(33):8674-8683
(IF: 7.882, Journal Ranking: 2, Number of Journals of this Field: 25, Ranking: 8.00%)

37

DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation.
拉賈,王志光,陳文正, 湯明哲,何美泠,黃啟清,王惠民,王昭仁* - - 1 - Journal of Cellular Physiology - J CELL PHYSIOL 2010 224卷(0期):387-397頁
(IF: 4.218, 領域排名: 12, 領域期刊數: 79, 領域排名: 15.19%)

DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation.
Raja E., Chih-Kuang Wang, Wen-Cheng Chen, Ming-Jer Tang, Mei-Ling Ho, Chi-Ching Hwang, Hui-Min Wang, Chau-Zen Wang* - - 1 - Journal of Cellular Physiology - J CELL PHYSIOL 2010;224(0):387-397
(IF: 4.218, Journal Ranking: 12, Number of Journals of this Field: 79, Ranking: 15.19%)

38

Discoidin domain receptor 1 activation suppressed alpha2beta1 integrin-dependent cell spreading through inhibition of Cdc42 activity.
Yeh, Y.C.,王昭仁, and Ming-Jer Tang* - - 1 - J Cell Physiol. - J CELL PHYSIOL 2009 218卷(0期):146–156頁
(IF: 4.313, 領域排名: 8, 領域期刊數: 74, 領域排名: 10.81%)

Discoidin domain receptor 1 activation suppressed alpha2beta1 integrin-dependent cell spreading through inhibition of Cdc42 activity.
Yeh, Y.C., Chau-Zen Wang, and Ming-Jer Tang* - - 1 - J Cell Physiol. - J CELL PHYSIOL 2009;218(0):146–156
(IF: 4.313, Journal Ranking: 8, Number of Journals of this Field: 74, Ranking: 10.81%)

39

DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading.
王昭仁 - - 1 - AM J PHYSIOL-CELL PH - AM J PHYSIOL-CELL PH 2009 297卷(2期):C419-429頁
(IF: 4.013, 領域排名: 13, 領域期刊數: 75, 領域排名: 17.33%)

DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading.
Chau-Zen Wang., Y.C. Yeh, and Ming-Jer Tang* - - 1 - AM J PHYSIOL-CELL PH - AM J PHYSIOL-CELL PH 2009;297(2):C419-429
(IF: 4.013, Journal Ranking: 13, Number of Journals of this Field: 75, Ranking: 17.33%)

40

Contributions of Active Site Residues to Cofactor Binding and Catalysis of 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase.
Yi-Hsun Chang, 王昭仁, 邱建智, 莊麗月, 黃啟清* - - 1 - BBA-PROTEINS PROTEOM - BBA-PROTEINS PROTEOM 2009 1804卷(1期):235-24頁
(IF: 2.48, 領域排名: 153, 領域期刊數: 283, 領域排名: 54.06%)

Contributions of Active Site Residues to Cofactor Binding and Catalysis of 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase.
Yi-Hsun Chang, Chau-Zen Wang, Chien-Chih Chiu, Lea-Yea Chuang, Chi-Ching Hwang. - - 1 - BBA-PROTEINS PROTEOM - BBA-PROTEINS PROTEOM 2009;1804(1):235-24
(IF: 2.48, Journal Ranking: 153, Number of Journals of this Field: 283, Ranking: 54.06%)

41

Low substratum rigidity of collagen gel promotes ERK phosphorylation via lipid raft to augment cell migration
Wei W.C., Y.C. Hsu, W.T. Chiu,王昭仁, C.M. Wu, Y.K. Wang, M.R. Shen and M.J. Tang. - - 1 - J CELL BIOCHEM - J CELL BIOCHEM 2008 103卷(4期):1111–1124.頁
(IF: 3.54, 領域排名: 69, 領域期刊數: 157, 領域排名: 43.95%)

Low substratum rigidity of collagen gel promotes ERK phosphorylation via lipid raft to augment cell migration
Wei W.C., Y.C. Hsu, W.T. Chiu, Chau-Zen Wang, C.M. Wu, Y.K. Wang, M.R. Shen and M.J. Tang* - - 1 - J CELL BIOCHEM - J CELL BIOCHEM 2008;103(4):1111–1124.
(IF: 3.54, Journal Ranking: 69, Number of Journals of this Field: 157, Ranking: 43.95%)

42

A discoidin domain receptor 1/SHP-2 signaling complex inhibits a2b1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration.
王昭 - - 1 - MOL BIOL CELL - MOL BIOL CELL 2006 17卷(0期):2839-52頁
(IF: 5.558, 領域排名: 32, 領域期刊數: 157, 領域排名: 20.38%)

A discoidin domain receptor 1/SHP-2 signaling complex inhibits a2b1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration.
Chau-Zen Wang., H.W. Su, Y.C. Hsu, M.R. Shen, and M.J. Tang*. - - 1 - MOL BIOL CELL - MOL BIOL CELL 2006;17(0):2839-52
(IF: 5.558, Journal Ranking: 32, Number of Journals of this Field: 157, Ranking: 20.38%)

43

Function of discoidin domain receptor I in HGF-induced branching tubulogenesis of MDCK cells in collagen gel.
王昭仁 - - 1 - J Cell Physiol. - J CELL PHYSIOL 2005 203卷(0期):295-304頁
(IF: 4.313, 領域排名: 8, 領域期刊數: 74, 領域排名: 10.81%)

Function of discoidin domain receptor I in HGF-induced branching tubulogenesis of MDCK cells in collagen gel.
Chau-Zen Wang., Y.M. Hsu, and M.J. Tang* - - 1 - J Cell Physiol. - J CELL PHYSIOL 2005;203(0):295-304
(IF: 4.313, Journal Ranking: 8, Number of Journals of this Field: 74, Ranking: 10.81%)

44

Rigidity of collagen fibrils controls collagen gel-induced down-regulation of focal adhesion complex proteins mediated by alpha2beta1 integrin.
Wang, Y.K., Y.H. Wang, Chau-Zen Wang, J.M. Sung, W.T. Chiu, S.H. Lin, Y.H. Chang, and M.J. Tang* - - 1 - JOURNAL OF BIOLOGICAL CHEMISTRY - J BIOL CHEM 2003 278卷(0期):21886-92頁
(IF: 6.482, 領域排名: 31, 領域期刊數: 261, 領域排名: 11.88%)

Rigidity of collagen fibrils controls collagen gel-induced down-regulation of focal adhesion complex proteins mediated by alpha2beta1 integrin.
Wang, Y.K., Y.H. Wang, Chau-Zen Wang, J.M. Sung, W.T. Chiu, S.H. Lin, Y.H. Chang, and M.J. Tang* - - 1 - JOURNAL OF BIOLOGICAL CHEMISTRY - J BIOL CHEM 2003;278(0):21886-92
(IF: 6.482, Journal Ranking: 31, Number of Journals of this Field: 261, Ranking: 11.88%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
112 — N 國科會(原科技部) — MOST111-2320-B-037-008-MY2 — 1 個人型
皮膚角質細胞特異性基因轉殖鼠研究:盤基蛋白受體1型的功能評估 (II)(2/2)( )
2023/08/01 ~ 2024/07/31
2
112 — Z 大專學生研究計畫及博士後 — NSTC112-2811-B-037-013 — 9 博士後研究員
博士級研究人員--Arokia Vijaya Anand( )
2023/08/01 ~ 2024/07/31
3
111 — N 國科會(原科技部) — MOST111-2320-B-037-008-MY2 — 1 個人型
皮膚角質細胞特異性基因轉殖鼠研究:盤基蛋白受體1型的功能評估 (II)(1/2)( )
2022/08/01 ~ 2024/07/31
4
111 — Z 大專學生研究計畫及博士後 — NSTC112-2811-B-037-001 — 9 博士後研究員
博士級研究人員--Arokia Vijaya Anand( )
2023/04/01 ~ 2023/07/31
5
110 — N 國科會(原科技部) — MOST110-2320-B-037-003 — 1 個人型
皮膚角質細胞特異性基因轉殖鼠研究:盤基蛋白受體1型的功能評估( )
2021/08/01 ~ 2022/07/31
6
109 — N 國科會(原科技部) — MOST109-2320-B-037-005 — 1 個人型
DDR1於角質形成細胞促進傷口癒合之研究( )
2020/08/01 ~ 2021/07/31
7
108 — N 國科會(原科技部) — MOST108-2320-B-037-008 — 1 個人型
研究軟骨細胞盤基蛋白結構域受體1在骨骼發育過程中調節軟骨內骨化的功能( )
2019/08/01 ~ 2020/07/31
8
108 — Z 大專學生研究計畫及博士後 — MOST109-2813-C-037-091-B — 8 大專學生研究計畫
109年度大專學生研究計畫-李金美(生物3)( )
2020/07/01 ~ 2021/02/28
9
107 — N 國科會(原科技部) — MOST105-2320-B-037-017-MY3 — 1 個人型
Discoidin domain receptor 1在骨骼發育異常及骨缺損再生功能之研究(3/3)( )
2018/08/01 ~ 2019/07/31
10
107 — Z 大專學生研究計畫及博士後 — MOST107-2811-B-037-511 — 9 博士後研究員
博士後研究員--林逸翔( )
2018/08/01 ~ 2019/07/31
11
106 — N 國科會(原科技部) — MOST105-2320-B-037-017-MY3 — 1 個人型
Discoidin domain receptor 1在骨骼發育異常及骨缺損再生功能之研究(2/3)( )
2017/08/01 ~ 2019/07/31
12
106 — Z 大專學生研究計畫及博士後 — MOST106-2811-B-037-013 — 9 博士後研究員
博士後研究員--林逸翔( )
2017/08/01 ~ 2018/07/31
13
105 — N 國科會(原科技部) — MOST105-2320-B-037-017-MY3 — 1 個人型
Discoidin domain receptor 1在骨骼發育異常及骨缺損再生功能之研究(1/3)( )
2016/08/01 ~ 2019/07/31
14
105 — TP 頂尖計畫(高醫) — KMU-TP105B13 —  
子計畫十三、以基因轉殖鼠模式探討Discoidin domain receptor 1 於骨質疏鬆症過程中的分子生物學機制( )
2016/11/01 ~ 2017/10/31
15
105 — Z 大專學生研究計畫及博士後 — MOST105-2811-B-037-033 — 9 博士後研究員
博士後研究員--林逸翔( )
2016/12/01 ~ 2017/07/31
16
104 — N 國科會(原科技部) — MOST104-2320-B-037-034 — 1 個人型
Discoidin domain receptor-1 (DDR1)基因在骨骼發育,骨質疏鬆症及退化性關節炎模式之角色探討: 骨母細胞特異性Ddr1基因剔除鼠及軟骨細胞特異性Ddr1基因剔除鼠研究( )
2015/08/01 ~ 2016/07/31
17
104 — TP 頂尖計畫(高醫) — KMU-TP104B12 —  
子計畫十二、以基因轉殖鼠模式探討Discoidin domain receptor-1 於骨與軟骨之發育與退化之分子生物學機制( )
2015/10/01 ~ 2016/09/30
18
103 — N 國科會(原科技部) — NSC101-2320-B-037-035-MY3 — 1 個人型
肌母細胞中Stathmin與Phosphoinositide 3-kinase在垂向震動促進肌管生成之機轉研究(3/3)( )
2014/08/01 ~ 2015/07/31
19
103 — TP 頂尖計畫(高醫) — KMU-TP103B09 —  
以基因轉殖鼠模式探討 Discoidin domain receptor-1 於骨與軟骨之發育與退化之分子生物學機制(Using transgenic mice model for studying the molecular mechanisms of Discoidin domain receptor-1 in the development and degeneration of bone and cartilage)
2014/08/01 ~ 2015/07/31
20
102 — N 國科會(原科技部) — NSC101-2320-B-037-035-MY3 — 1 個人型
肌母細胞中Stathmin與Phosphoinositide 3-kinase在垂向震動促進肌管生成之機轉研究(2/3)( )
2013/08/01 ~ 2015/07/31
21
101 — N 國科會(原科技部) — NSC101-2320-B-037-035-MY3 — 1 個人型
肌母細胞中Stathmin與Phosphoinositide 3-kinase在垂向震動促進肌管生成之機轉研究(1/3)( )
2012/08/01 ~ 2015/07/31
22
100 — M 高醫(種子計畫) — KMU-M110006 —  
體外3D培養模式與裸鼠及兔子關節軟骨缺損模式-探討膠原蛋白接受體Discoidin domail receptors在脂肪幹細胞軟骨分化機轉之角色與關節軟骨再生研究( )
2011/12/15 ~ 2012/12/31
23
099 — M 高醫(種子計畫) — KMU-M100013 —  
膠原蛋白接受體Discoidin domain receptor(DDR)調控人類脂肪幹細胞軟骨分化之機制與關節軟骨組織工程研究( )
2011/01/01 ~ 2011/12/31
24
098 — N 國科會(原科技部) — NSC98-2320-B-037-021 — 1 個人型
DDR1/E-cadherin複合體之功能性研究( )
2009/08/01 ~ 2010/07/31
25
097 — N 國科會(原科技部) — NSC97-2314-B-037-050 — 1 個人型
Discoidin domain receptor 1 與 E-cadherin結合與交互調節之研究( )
2008/10/01 ~ 2009/07/31
26
097 — Q 新聘教師計畫(校內) — KMU-Q098005 —  
膠原蛋白接受體(Discoidin domain receptor)對脂肪幹細胞之促軟骨分化哼的軟骨新生之細胞訊息傳遞研究( )
2009/01/01 ~ 2009/12/31
27
096 — Q 新聘教師計畫(校內) —   —  
雙林酸鹽類(Alendronate)藥物,對骨隨幹細胞之促骨分化後的骨質新生之細胞訊息傳遞研究( )
2007/11/01 ~ 2008/07/31

 Patent

NO Patent Name Country Certified Date Patent No
1 盤基蛋白結構域受體1的抑制劑及活化劑及其用途 中華民國 2019/11/11 I676482
2 促骨新生及骨缺損修復藥物Obtusilactone A之用途 中華民國 2019/07/21 I666017
3 盤基蛋白結構域受體1的抑制劑及活化劑及其用途 世界專利(美國) 2021/03/16 10,946,021