Education
| School — Major — Degree | Duration |
|---|---|
|
國立國防大學 — 生命科學研究所(畢) — 博士 Doctorate, , |
1996/06 — 2001/06 |
|
臺北醫學院 — 醫學研究所(畢) — 碩士 Master, , |
1993/09 — 1995/06 |
|
輔仁大學 — 食品營養學系(畢) — 學士 Bachelor, , |
1989/09 — 1993/06 |
Intramural Experience
| Office/Department/Institute | Position | Duration |
|---|---|---|
| 醫學研究所 Graduate Institute of Medicine | Professor | 2017/08/01 — |
| 醫學研究所 Graduate Institute of Medicine | Associate Professor | 2013/03/01 — 2017/07/31 |
| 醫學研究所 Graduate Institute of Medicine | Assistant Professor | 2005/08/01 — 2013/02/28 |
Extramural Experience
Discipline
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
免疫學, 退化性疾病及代謝相關疾病
Immunology, degeneration disease and metabolism syndrome.
Area(s) of Expertise & Research
Wntless、Spzl、Isx and U gene分子細胞生物學,發育生物學,分子遺傳學,基因轉殖,基因剔除
Molecular oncology, Development biology, Molecular genetics,transgenic mice, Gene targeting
Publication
| NO | Publication |
|---|---|
| 1 | Polycyclic aromatic hydrocarbon aggravates high-fat diet-induced metabolic dysfunction-associated steatotic liver disease through disturbing hepatocyte sphingolipid metabolism. Polycyclic aromatic hydrocarbon aggravates high-fat diet-induced metabolic dysfunction-associated steatotic liver disease through disturbing hepatocyte sphingolipid metabolism. |
| 2 | Macrophage MRC2 Deficiency Mitigates HFD-Induced MASLD by Downregulating CD147-Regulated TNF-α Production Macrophage MRC2 Facilitates MASLD via the CD147-TNF-α Axis Macrophage MRC2 Deficiency Mitigates HFD-Induced MASLD by Downregulating CD147-Regulated TNF-α Production Macrophage MRC2 Facilitates MASLD via the CD147-TNF-α Axis |
| 3 | Harnessing the Transcriptional Signatures of CAR-T-Cells and Leukemia/Lymphoma Using Single-Cell Sequencing Technologies. Harnessing the Transcriptional Signatures of CAR-T-Cells and Leukemia/Lymphoma Using Single-Cell Sequencing Technologies. |
| 4 | The Current and Prospective Adjuvant Therapies for Hepatocellular Carcinoma. The Current and Prospective Adjuvant Therapies for Hepatocellular Carcinoma. |
| 5 | Deferasirox Causes Leukaemia Cell Death through Nrf2-Induced Ferroptosis. Deferasirox Causes Leukaemia Cell Death through Nrf2-Induced Ferroptosis. |
| 6 | Wnt 分泌調控蛋白訊息在癌症形成的角色 Role of Wnt Ligand Secretion Mediator Signaling in Cancer Development |
| 7 | Di(2-ethylhexyl) phthalate mediates IL-33 production aryl hydrocarbon receptor and is associated with childhood allergy development. Di(2-ethylhexyl) phthalate mediates IL-33 production aryl hydrocarbon receptor and is associated with childhood allergy development. |
| 8 | Recent Advances in Transcription Factors Biomarkers and Targeted Therapies Focusing on Epithelial-Mesenchymal Transition. Recent Advances in Transcription Factors Biomarkers and Targeted Therapies Focusing on Epithelial-Mesenchymal Transition. |
| 9 | HCV Core Protein-ISX Axis Promotes Chronic Liver Disease Progression via Metabolic Remodeling and Immune Suppression. HCV Core Protein-ISX Axis Promotes Chronic Liver Disease Progression via Metabolic Remodeling and Immune Suppression. |
| 10 | Insights into Hepatocellular Carcinoma in Patients with Thalassemia: From Pathophysiology to Novel Therapies. Insights into Hepatocellular Carcinoma in Patients with Thalassemia: From Pathophysiology to Novel Therapies. |
| 11 | Aryl hydrocarbon receptor-kynurenine axis promotes oncogenic activity in BCP-ALL. Aryl hydrocarbon receptor-kynurenine axis promotes oncogenic activity in BCP-ALL. |
| 12 | WLS/wntless 在通過 WNT 信號獨立機制控制樹突細胞穩態方面至關重要 WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism |
| 13 | Aryl Hydrocarbon Receptor is Essential in the Control of Lung Club Cell Homeostasis. Aryl Hydrocarbon Receptor is Essential in the Control of Lung Club Cell Homeostasis. |
| 14 | Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity. Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity. |
| 15 | Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. |
| 16 | Hyperbaric Oxygen Therapy Alleviates the Autoimmune Encephalomyelitis via the Reduction of IL-17a and GM-Csf Production of Autoreactive T Cells as Well as Boosting the Immunosuppressive IL-10 in the Central Nervous System Tissue Lesions Hyperbaric Oxygen Therapy Alleviates the Autoimmune Encephalomyelitis via the Reduction of IL-17a and GM-Csf Production of Autoreactive T Cells as Well as Boosting the Immunosuppressive IL-10 in the Central Nervous System Tissue Lesions |
| 17 | PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition |
| 18 | TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial-mesenchymal transition and metastasis in liver cancer. TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial-mesenchymal transition and metastasis in liver cancer. |
| 19 | Homeobox Genes and Hepatocellular Carcinoma Homeobox Genes and Hepatocellular Carcinoma |
| 20 | Modification of Epigenetic Histone Acetylation in Hepatocellular Carcinoma. Modification of Epigenetic Histone Acetylation in Hepatocellular Carcinoma. |
| 21 | Human non‑small cell lung cancer cells can be sensitized to camptothecin by modulating autophagy Human non‑small cell lung cancer cells can be sensitized to camptothecin by modulating autophagy |
| 22 | Transcription factor SPZ1 promotes TWIST-mediated epithelial–mesenchymal transition and oncogenesis in human liver cancer Transcription factor SPZ1 promotes TWIST-mediated epithelial–mesenchymal transition and oncogenesis in human liver cancer |
| 23 | 芳香烴受體在肝癌中調節蛋白脫乙酰酶8表達抑制腫瘤抑制基因活性 Aryl hydrocarbon receptor regulates histone deacetylase 8 expression to repress tumor suppressive activity in hepatocellular carcinoma. |
| 24 | Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine-specific homeobox expression Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine-specific homeobox expression |
| 25 | Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage |
| 26 | Intestine-specific homeobox gene ISX integrates interleukin-6 signaling, tryptophan metabolism, and immune suppression Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression. |
| 27 | 小腸特異性箱型基因ISX在肝癌中調控E2F1與致癌的活性 Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC |
| 28 | Tenuifolide B from Cinnamomum tenuifolium stem inhibits proliferation of oral cancer cells via apoptosis, ROS generation, mitochondrial depolarization, and DNA damage Tenuifolide B from Cinnamomum tenuifolium stem inhibits proliferation of oral cancer cells via apoptosis, ROS generation, mitochondrial depolarization, and DNA damage |
| 29 | HCV NS5A 透過IL-8-mediated 活化 ERK/JNK MAPK 路徑而誘導COX-2 表現 HCV NS5A up-regulates COX-2 expression via IL-8-mediated activation of the ERK/JNK MAPK pathway. |
| 30 | Nanomolar naloxone attenuates neurotoxicity induced by oxidative stress and survival motor neuron protein deficiency Nanomolar naloxone attenuates neurotoxicity induced by oxidative stress and survival motor neuron protein deficiency |
| 31 | p38 MAPK在人類泌尿上皮癌gemcitabine抗藥株的角色探討 Involvement of p38 MAPK in acquired gemcitabine-resistant human urothelial carcinoma sublines |
| 32 | Wntless (GPR177) expression correlates with poor prognosis in B-cell precursor acute lymphoblastic leukemia via Wnt signaling Wntless (GPR177) expression correlates with poor prognosis in B-cell precursor acute lymphoblastic leukemia via Wnt signaling |
| 33 | Survival of motor neuron protein downregulates miR-9 expression in patients with spinal muscular atrophy Survival of motor neuron protein downregulates miR-9 expression in patients with spinal muscular atrophy |
| 34 | Survival of motor neuron protein downregulates miR-9 expression in patients with spinal muscular atrophy. Survival of motor neuron protein downregulates miR-9 expression in patients with spinal muscular atrophy. |
| 35 | 抑制組織胺第一型受體之活性可以抑制樹突細胞之功能 Inhibition of histamine H1 receptor activity modulates proinflammatory cytokine production of dendritic cells through c-Rel activity |
| 36 | 發炎相關恆定基因ISX和肝癌的關係 Pro-Inflammatory Homeobox Gene, ISX, Regulates Tumor growth and Survival in Hepatocellular Carcinoma |
| 37 | 環境賀爾蒙壬基苯酚可促進小鼠動物模式之過敏性發炎 A common environmental pollutant, 4-nonylphenol, promotes allergic lung inflammation in a murine model of asthma |
| 38 | 肝臟移植後C型肝炎復發的新知探討 New insights in recurrent HCV infection after liver transplantation |
| 39 | 探討哺乳動物Wntless同源物在哺乳動物系統功能表徵 Functional characterization of mammalian Wntless homolog in mammalian system |
| 40 | Functional interaction of Ugene and EBV infection mediates tumorigenic effects Functional interaction of Ugene and EBV infection mediates tumorigenic effects |
| 41 | 相思樹萃取物藉由抑制環氧合酶-2 達到抗C 型肝炎病毒活性 Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2 |
| 42 | 以體外轉錄/轉譯報告系統檢測C型肝炎病毒RNA聚合酶活性 An in vitro coupled transcription/translation reporter system for hepatitis C virus RNA-dependent RNA polymerase |
| 43 | UCHL1調控SMN蛋白質表現量 Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulates the level of SMN expression through ubiquitination in primary spinal muscular atrophy fibroblasts |
| 44 | 氣喘兒童使用白三烯抑制劑後血漿中MMP-9下降 Suppression of plasma matrix metalloproteinase-9 following montelukast treatment in childhood asthma |
| 45 | 氣喘兒童在惡化時第一型幫助型T細胞激素的表現 T-helper 1-related chemokines in the exacerbation of childhood asthma |
| 46 | formoterol 及 salmeterol對單核球及支氣管上皮細胞Th1 and Th2 相關趨化激素表現之影響 Effects of formoterol and salmeterol on the production of Th1- and Th2-related chemokines by monocytes and bronchial epithelial cells |
Project
| NO |
YEAR — Source — No — Type
Project Name
|
Duration |
|---|---|---|
| 1 |
115 — N 國科會(原科技部) — NSTC113-2320-B-037-028-MY3 — 1 個人型
探討ISX-CD47訊號軸在腫瘤微環境中對巨噬細胞功能調控促使肝癌惡化及抗藥性之相關影響及機轉(3/3)( )
|
2026/08/01 ~ 2027/07/31 |
| 2 |
114 — N 國科會(原科技部) — NSTC113-2320-B-037-028-MY3 — 1 個人型
探討ISX-CD47訊號軸在腫瘤微環境中對巨噬細胞功能調控促使肝癌惡化及抗藥性之相關影響及機轉(2/3)( )
|
2025/08/01 ~ 2027/07/31 |
| 3 |
113 — N 國科會(原科技部) — NSTC113-2320-B-037-028-MY3 — 1 個人型
探討ISX-CD47訊號軸在腫瘤微環境中對巨噬細胞功能調控促使肝癌惡化及抗藥性之相關影響及機轉(1/3)( )
|
2024/08/01 ~ 2027/07/31 |
| 4 |
112 — DK 前瞻重點(原校院) — KMU-DK(A)113009 —
探討肝癌細胞中 ISX 如何調控腫瘤微環境中巨噬細胞之極性轉變( )
|
2024/01/01 ~ 2024/12/31 |
| 5 |
112 — N 國科會(原科技部) — MOST110-2314-B-037-072-MY3 — 1 個人型
發現及探討代謝性失衡誘發肝癌之早期基因表現、作用及生物標靶(3/3)( )
|
2023/08/01 ~ 2024/07/31 |
| 6 |
112 — N 國科會(原科技部) — NSTC112-2320-B-037-004 — 2 整合型
研究腸道特異性同源箱(intestine-specific homeobox; ISX)-誘導的脂質代謝失衡在慢性肝病的影響-探討飲食脂質調控肝臟ISX-RXR訊號軸在NAFLD中脂質異常堆積的調控作用(3/3)( )
|
2023/08/01 ~ 2024/07/31 |
| 7 |
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-055-B — 8 大專學生研究計畫
113年度大專學生研究計畫-吳庠霖(醫學2)( )
|
2024/07/01 ~ 2025/02/28 |
| 8 |
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-073-B — 8 大專學生研究計畫
113年度大專學生研究計畫-黃珮嫻(臺灣師範大學生命科學系3)( )
|
2024/07/01 ~ 2025/02/28 |
| 9 |
111 — DK 前瞻重點(原校院) — KMU-DK(A)112002 — 1 個人型
探討SPZ1-SMN 訊號軸線調控WLS伴隨蛋白複合體所誘發之內質網壓力在神經肌肉萎縮症疾病上所做為新治療方式的可能性及調控機轉( )
|
2023/01/01 ~ 2023/12/31 |
| 10 |
111 — N 國科會(原科技部) — MOST110-2314-B-037-072-MY3 — 1 個人型
發現及探討代謝性失衡誘發肝癌之早期基因表現、作用及生物標靶(2/3)( )
|
2022/08/01 ~ 2024/07/31 |
| 11 |
111 — N 國科會(原科技部) — MOST111-2320-B-037-031 — 2 整合型
研究腸道特異性同源箱(intestine-specific homeobox ISX)-誘導的脂質代謝失衡在慢性肝病的影響-探討飲食脂質調控肝臟ISX-RXR訊號軸在NAFLD中脂質異常堆積的調控作用(2/3)( )
|
2022/08/01 ~ 2023/07/31 |
| 12 |
110 — N 國科會(原科技部) — MOST110-2320-B-037-008 — 2 整合型
研究腸道特異性同源箱(intestine-specific homeobox ISX)-誘導的脂質代謝失衡在慢性肝病的影響-探討飲食脂質調控肝臟ISX-RXR訊號軸在NAFLD中脂質異常堆積的調控作用(1/3)( )
|
2021/08/01 ~ 2022/07/31 |
| 13 |
110 — N 國科會(原科技部) — MOST110-2314-B-037-072-MY3 — 1 個人型
發現及探討代謝性失衡誘發肝癌之早期基因表現、作用及生物標靶(1/3)( )
|
2021/08/01 ~ 2024/07/31 |
| 14 |
109 — N 國科會(原科技部) — MOST107-2314-B-037-028-MY3 — 1 個人型
發現及探討脂肪肝轉變成肝臟纖維化及肝癌發生之前驅生物因子及相關機轉探討: 以高脂飲食誘發箱型基因ISX基因轉殖小鼠肝纖維化及肝癌模式為平台(3/3)( )
|
2020/08/01 ~ 2021/07/31 |
| 15 |
109 — Z 大專學生研究計畫及博士後 — MOST110-2813-C-037-040-B — 8 大專學生研究計畫
110年度大專學生研究計畫-陳宇彤(生物3)( )
|
2021/07/01 ~ 2022/02/28 |
| 16 |
108 — N 國科會(原科技部) — MOST107-2314-B-037-028-MY3 — 1 個人型
發現及探討脂肪肝轉變成肝臟纖維化及肝癌發生之前驅生物因子及相關機轉探討: 以高脂飲食誘發箱型基因ISX基因轉殖小鼠肝纖維化及肝癌模式為平台(2/3)( )
|
2019/08/01 ~ 2021/07/31 |
| 17 |
108 — TC 研究中心計畫 — KMU-TC108A04-5 — 6 研究中心
探討轉錄因子ISX 在脂質代謝、慢性肝病和肝癌中的關鍵調控角色和機制( )
|
2019/08/01 ~ 2020/07/31 |
| 18 |
107 — DK 前瞻重點(原校院) — KMU-DK108012 —
探討內質網壓力調控缺失對免疫系統功能之影響：以樹突細胞專一性剔除內質蛋白-Wntless隻小鼠模式為平台( )
|
2018/08/01 ~ 2019/07/31 |
| 19 |
107 — N 國科會(原科技部) — MOST107-2314-B-037-028-MY3 — 1 個人型
發現及探討脂肪肝轉變成肝臟纖維化及肝癌發生之前驅生物因子及相關機轉探討: 以高脂飲食誘發箱型基因ISX基因轉殖小鼠肝纖維化及肝癌模式為平台(1/3)( )
|
2018/08/01 ~ 2021/07/31 |
| 20 |
106 — N 國科會(原科技部) — MOST105-2314-B-037-070-MY2 — 1 個人型
探討表觀調節基因PCAF對致癌基因轉錄體ISX-Brd4-RNApo1II在肝癌微環境及轉移上之調控機轉及臨床預後之觀察(2/2)( )
|
2017/08/01 ~ 2018/07/31 |
| 21 |
105 — N 國科會(原科技部) — MOST105-2314-B-037-070-MY2 — 1 個人型
探討表觀調節基因PCAF對致癌基因轉錄體ISX-Brd4-RNApo1II在肝癌微環境及轉移上之調控機轉及臨床預後之觀察(1/2)( )
|
2016/08/01 ~ 2018/07/31 |
| 22 |
105 — Z 大專學生研究計畫及博士後 — MOST105-2811-B-037-029 — 9 博士後研究員
博士後研究員--王麗婷( )
|
2016/10/01 ~ 2017/07/31 |
| 23 |
104 — N 國科會(原科技部) — NSC102-2320-B-037-032-MY3 — 1 個人型
探討環境毒物受體AhR對致癌箱型基因ISX在人類肝癌發生及調控所扮演的角色(3/3)( )
|
2015/08/01 ~ 2016/07/31 |
| 24 |
104 — OX 其他單位(非研究) — 工業技術研究院 —
腫瘤臨床樣本甲基化標記測試( )
|
2015/08/01 ~ 2015/12/31 |
| 25 |
104 — TP 頂尖計畫(高醫) — KMU-TP104E10 —
子計畫十、探討箱型致癌基因ISX在HCV感染之脂肪肝病人中之調控機轉( )
|
2015/10/01 ~ 2016/09/30 |
| 26 |
104 — Z 大專學生研究計畫及博士後 — MOST105-2815-C-0378-041-B — 8 大專學生研究計畫
105年度大專學生研究計畫- 楊佩姍(生技3)( )
|
2016/07/01 ~ 2017/02/28 |
| 27 |
103 — N 國科會(原科技部) — NSC102-2320-B-037-032-MY3 — 1 個人型
探討環境毒物受體AhR對致癌箱型基因ISX在人類肝癌發生及調控所扮演的角色(2/3)( )
|
2014/08/01 ~ 2016/07/31 |
| 28 |
103 — Z 大專學生研究計畫及博士後 — 104-2815-C-037-003-B — 8 大專學生研究計畫
104年度大專學生研究計畫-蔡佳倪(生物3)( )
|
2015/07/01 ~ 2016/02/29 |
| 29 |
103 — Z 大專學生研究計畫及博士後 — 104-2815-C-037-023-B — 8 大專學生研究計畫
104年度大專學生研究計畫-林長億(生物3)( )
|
2015/07/01 ~ 2016/02/29 |
| 30 |
102 — N 國科會(原科技部) — NSC102-2320-B-037-032-MY3 — 1 個人型
探討環境毒物受體AhR對致癌箱型基因ISX在人類肝癌發生及調控所扮演的角色(1/3)( )
|
2013/08/01 ~ 2016/07/31 |
| 31 |
102 — Z 大專學生研究計畫及博士後 — 103-2815-C-037-010-B — 8 大專學生研究計畫
103年度大專學生研究計畫-李益亘(生物3)( )
|
2014/07/01 ~ 2015/02/28 |
| 32 |
101 — N 國科會(原科技部) — NSC101-2320-B-037-042 — 1 個人型
探討LMPIP基因在鼻咽癌轉移及血管新生中調控機轉之研究( )
|
2012/08/01 ~ 2013/07/31 |
| 33 |
100 — N 國科會(原科技部) — NSC98-2320-B-037-026-MY3 — 1 個人型
建立誘發性Wntless核醣核酸干擾小鼠及分析該基因在癌症發生之生理功能(3/3)( )
|
2011/08/01 ~ 2012/07/31 |
| 34 |
099 — N 國科會(原科技部) — NSC98-2320-B-037-026-MY3 — 1 個人型
建立誘發性Wntless核醣核酸干擾小鼠及分析該基因在癌症發生之生理功能(2/3)( )
|
2010/08/01 ~ 2012/07/31 |
| 35 |
099 — Z 大專學生研究計畫及博士後 — NSC100-2815-C-037-022-B — 8 大專學生研究計畫
100年度大專學生參與專題研究計畫--陳善維(生物系3)( )
|
2011/07/01 ~ 2012/02/29 |
| 36 |
098 — N 國科會(原科技部) — NSC98-2320-B-037-026-MY3 — 1 個人型
建立誘發性Wntless核醣核酸干擾小鼠及分析該基因在癌症發生之生理功能(1/3)( )
|
2009/08/01 ~ 2012/07/31 |
| 37 |
098 — Z 大專學生研究計畫及博士後 — NSC99-2815-C-037-020-B — 8 大專學生研究計畫
99年度大專學生參與專題研究計畫-朱育儀( )
|
2010/07/01 ~ 2011/02/28 |
| 38 |
097 — N 國科會(原科技部) — NSC97-2314-B-037-015 — 1 個人型
建立基因轉殖及剔除小鼠探討致癌基因-Wntless之細胞及生理功能( )
|
2008/08/01 ~ 2009/07/31 |
| 39 |
096 — N 國科會(原科技部) — NSC95-2314-B-037-043-MY2 — 1 個人型
以基因剔除的方式建立及分析致癌基因Spz1之生理功能(2/2)( )
|
2007/08/01 ~ 2008/07/31 |
| 40 |
096 — Y 高醫-彰基合作計畫 — 97-CCH-KMU-024 — 1 個人型
探討NF-Κb活化蛋白,IKKAP(IKKα-activation protein),在小兒急性淋巴癌中所扮演之角色( )
|
2008/01/01 ~ 2008/12/31 |
| 41 |
096 — Z 大專學生研究計畫及博士後 — 97-2815-C-037-010-B — 8 大專學生研究計畫
97年度大專學生參與專題研究計畫--黃孟苓( )
|
2008/07/01 ~ 2009/02/28 |
| 42 |
095 — N 國科會(原科技部) — NSC95-2314-B-037-043-MY2 — 1 個人型
以基因剔除的方式建立及分析致癌基因SPZ1 之生理功能(1/2)( )
|
2006/08/01 ~ 2008/07/31 |
| 43 |
095 — Q 新聘教師計畫(校內) — — 1 個人型
經由尋找交互作用蛋白探討膜蛋白Wntless之細胞功能(Study the cellular regulation mechanism of menbrance protein, Wntless, interaction protein)
|
2006/12/01 ~ 2007/07/31 |
| 44 |
095 — X 高奇合作計畫 — 96CM-KMU-07 — 1 個人型
以去氧核醣核酸微陣列探討SMA疾病發生機轉( )
|
2007/04/01 ~ 2008/03/31 |
| 45 |
094 — N 國科會(原科技部) — NSC 94-2312-B-037-001- — 1 個人型
以基因剔除的方式建立及分析致癌基因SPZ1之生理功能( )
|
2005/08/01 ~ 2006/07/31 |
| 46 |
094 — Q 新聘教師計畫(校內) — — 1 個人型
探討致癌基因SPZL交互作用蛋白對致癌機轉的影響( )
|
2005/10/01 ~ 2006/07/31 |
Patent
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| 1 | 用於調控脊髓肌肉萎縮基因1表現量之醫藥組合物以及於人類纖維母細胞中偵測泛?素基端水解?L1酵素活性的方法 | 美國 | 2015/06/02 | 9,045,793 |
| 2 | Tenuifolide B化合物於製備供選擇性殺死口腔癌細胞之醫藥組合物之用途 | 中華民國 | 2018/04/21 | I621433 |
| 3 | 肝病變的小鼠模式的製備方法及其應用 | 中華民國 | 2021/04/01 | I723562 |
| 4 | 箱型基因-ISX-基因轉殖肝臟疾病模式 | 美國 | 2023/10/31 | 11,800,857 |