Education
| School — Major — Degree | Duration |
|---|---|
|
高雄醫學大學 — 醫學研究所(畢) — 博士 Doctorate, , |
1996/09 — 2000/06 |
|
高雄醫學院 — 醫學研究所(畢) — 碩士 Master, , |
1994/09 — 1996/06 |
|
高雄醫學院 — 護理學系(畢) — 學士 Bachelor, , |
1988/09 — 1992/06 |
Intramural Experience
| Office/Department/Institute | Position | Duration |
|---|---|---|
| 教務處註冊課務組 Registration and Curriculum Division | Head | 2025/08/01 — 2026/07/31 |
| 環境職業醫學博士學位學程 PhD Program in Environmental and Occupational Medicine | Chair | 2024/08/01 — 2027/07/31 |
| 醫學研究所 Graduate Institute of Medicine | Professor | 2022/02/01 — |
| 醫學研究所 Graduate Institute of Medicine | Associate Professor | 2015/08/01 — 2022/01/31 |
| 基因體醫學科 Department of Genomic Medicine | Assistant Professor | 2012/08/01 — 2012/04/30 |
| 基因體醫學科 Department of Genomic Medicine | Associate Professor | 2012/05/01 — 2015/07/31 |
| 醫學遺傳學科 Department of Genetic Medicine | Assistant Professor | 2007/08/01 — 2012/07/31 |
| 醫學遺傳研究所 Graduate Institute of Medical Genetics | Assistant Professor | 2004/09/01 — 2007/07/31 |
Extramural Experience
Discipline
| NO | Discipline | Expertise |
|---|---|---|
| 1 | 生物醫農類 Biology, Medicine and Agriculture | 生技製藥國家型科技計畫 National Science and Technology Program for Biotechnology and Pharmaceuticals |
| 2 | 生物醫農類 Biology, Medicine and Agriculture | 基因體醫學國家型科技計畫 National Research Program for Genomic Medicine (NRPGM) |
| 3 | 生物醫農類 Biology, Medicine and Agriculture | 醫學之生化及分子生物 Medical Biochemistry and Molecular Biology |
| 4 | 生物醫農類 Biology, Medicine and Agriculture | 腎臟科、新陳代謝及內分泌 Division of Nephrology, Division of Metabolism & Endocrinology |
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
任何領域
any
Area(s) of Expertise & Research
新陳代謝症候群、肥胖、糖尿病、動脈硬化及腎臟病變相關疾病之病理分子機轉研究及新藥開發、基因體學分析、分子生物實驗技術、細胞培養與動物疾病模式、環境醫學
Molecular mechanism investigation and drug development of metabolic diseases, diabetes, obesity, kidney disease, and atherosclerosis; molecular biology; genomics; cell and animal experimental models; environmental medicine.
Publication
| NO | Publication |
|---|---|
| 1 | Association of ADH1B and ALDH2 genotypes with the risk of lung adenocarcinoma. Association of ADH1B and ALDH2 genotypes with the risk of lung adenocarcinoma. |
| 2 | New insights into coordinated regulation of AHR promoter transcription; molecular mechanisms and therapeutic targets. New insights into coordinated regulation of AHR promoter transcription; molecular mechanisms and therapeutic targets. |
| 3 | 經氧化壓力引發腎損傷指標的三聚氰胺暴露基準劑量：以尿路結石患者和職業工人為例 Benchmark Dose of Melamine Exposure for a Renal Injury Marker Mediated by Oxidative Stress: Examples in Patients with Urolithiasis and Occupational Workers. |
| 4 | 鄰苯二甲酸酯暴露增加氧化壓力、早期腎損傷及含鈣尿路結石之風險：以病例對照研究為例 Phthalate exposure increases oxidative stress, early renal injury, and the risk of calcium urolithiasis: A case-control study. |
| 5 | Environmental melamine exposure and adverse kidney outcomes in patients with type 2 diabetes mellitus. Environmental melamine exposure and adverse kidney outcomes in patients with type 2 diabetes mellitus. |
| 6 | Sex-specific interactive effect of melamine and DEHP on a marker of early kidney damage in Taiwanese adults: A national population-based study from the Taiwan Biobank. Sex-specific interactive effect of melamine and DEHP on a marker of early kidney damage in Taiwanese adults: A national population-based study from the Taiwan Biobank. |
| 7 | Rapid identification and monitoring of cooking oil fume-based toxic volatile organic aldehydes in lung tissue for predicting exposure level and cancer risks. Rapid identification and monitoring of cooking oil fume-based toxic volatile organic aldehydes in lung tissue for predicting exposure level and cancer risks. |
| 8 | 代謝異常脂肪肝為未具代謝症候群之老化男性罹患睪固酮低下症之早期預測因子 Metabolic dysfunction-associated fatty liver disease is an early predictor for testosterone deficiency in aging men without metabolic syndrome. |
| 9 | Genetic Polymorphisms of MnSOD Modify the Impacts of Environmental Melamine on Oxidative Stress and Early Kidney Injury in Calcium Urolithiasis Patients. Genetic Polymorphisms of MnSOD Modify the Impacts of Environmental Melamine on Oxidative Stress and Early Kidney Injury in Calcium Urolithiasis Patients. |
| 10 | Relationship of maternal body weight and gestational diabetes mellitus with large-for-gestational-age babies at birth in Taiwan: The TMICS cohort. Relationship of maternal body weight and gestational diabetes mellitus with large-for-gestational-age babies at birth in Taiwan: The TMICS cohort. |
| 11 | N-Octyl Caffeamide, a Caffeic Acid Amide Derivative, Prevents Progression of Diabetes and Hepatic Steatosis in High-Fat Diet Induced Obese Mice. N-Octyl Caffeamide, a Caffeic Acid Amide Derivative, Prevents Progression of Diabetes and Hepatic Steatosis in High-Fat Diet Induced Obese Mice. |
| 12 | Benchmark dose in the presence of coexposure to melamine and diethylhexyl phthalate and urinary renal injury markers in pregnant women. Benchmark dose in the presence of coexposure to melamine and diethylhexyl phthalate and urinary renal injury markers in pregnant women. |
| 13 | 低能量體外震波用於糖尿型膀胱過動症之療效：從動物模式到臨床應用 Therapeutic effect of Low intensity Extracorporeal Shock Wave Therapy (Li-ESWT) on diabetic bladder dysfunction in a rat model |
| 14 | 使用新式油煙桶減少油煙中醛類排放 Reduction of aldehyde emission and attribution of environment burden in cooking fumes from food stalls using a novel fume collector |
| 15 | 中式職業廚師中兩種常見的腺細胞型癌症（乳腺癌和結直腸癌）的風險：台灣的一項全國性生態研究。 Risk of two common glandular cell-type cancers (breast and colorectal cancers) in Chinese occupational chefs: a nationwide ecological study in Taiwan. |
| 16 | Melamine exposure threshold in early chronic kidney disease patients–A benchmark dose approach Melamine exposure threshold in early chronic kidney disease patients–A benchmark dose approach |
| 17 | Fatty liver index is associated with the risk of testosterone deficiency in aging men without metabolic syndrome. Fatty liver index is associated with the risk of testosterone deficiency in aging men without metabolic syndrome. |
| 18 | Melamine and oxalate coexposure induces early kidney tubular injury through mitochondrial aberrations and oxidative stress. Melamine and oxalate coexposure induces early kidney tubular injury through mitochondrial aberrations and oxidative stress. |
| 19 | Diminishment of Nrf2 Antioxidative Defense Aggravates Nephrotoxicity of Melamine and Oxalate Coexposure. Diminishment of Nrf2 Antioxidative Defense Aggravates Nephrotoxicity of Melamine and Oxalate Coexposure. |
| 20 | Diversity-oriented synthesis through gamma radiolysis: Preparation of unusual ecdysteroid derivatives activating Akt and AMPK in skeletal muscle cells. Diversity-oriented synthesis through gamma radiolysis: Preparation of unusual ecdysteroid derivatives activating Akt and AMPK in skeletal muscle cells. |
| 21 | Interrelationship of environmental melamine exposure, biomarkers of oxidative stress and early kidney injury. Interrelationship of environmental melamine exposure, biomarkers of oxidative stress and early kidney injury. |
| 22 | 利用質譜儀鑑定不同藥物共同處理細胞後之重要的蛋白質標記：體外篩選平台 Identification of significant protein markers by mass spectrometry after co-treatment of cells with different drugs: An in vitro survey platform. |
| 23 | A probabilistic approach for benchmark dose of melamine exposure for a marker of early renal dysfunction in patients with calcium urolithiasis. A probabilistic approach for benchmark dose of melamine exposure for a marker of early renal dysfunction in patients with calcium urolithiasis. |
| 24 | 微波輔助衍生反應結合凝聚提取法並配合毛細管液相層析法測定生物基質樣品中的穀胱甘肽 Microwave-assisted derivatization combined with coacervative extraction for determining glutathione in biomatrix samples, followed by capillary liquid chromatography |
| 25 | Urinary Melamine Levels and Progression of CKD Urinary Melamine Levels and Progression of CKD |
| 26 | 2-Bromo-4'-methoxychalcone and 2-Iodo-4'-methoxychalcone Prevent Progression of Hyperglycemia and Obesity via 5'-Adenosine-Monophosphate-Activated Protein Kinase in Diet-Induced Obese Mice. 2-Bromo-4'-methoxychalcone and 2-Iodo-4'-methoxychalcone Prevent Progression of Hyperglycemia and Obesity via 5'-Adenosine-Monophosphate-Activated Protein Kinase in Diet-Induced Obese Mice. |
| 27 | Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men |
| 28 | Urinary melamine excretion and increased markers of renal tubular injury in patients with calcium urolithiasis: A cross-sectional study Urinary melamine excretion and increased markers of renal tubular injury in patients with calcium urolithiasis: A cross-sectional study |
| 29 | Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis |
| 30 | 以質譜儀搭配生物資訊策略分析丙戊酸引起之蛋白質表現與修飾 A mass spectrometry-based strategy combined with bioinformatics: A simple preclinical model for profiling valproic-acid-induced major proteins and modifications in human liver cells |
| 31 | 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice. 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice. |
| 32 | Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy |
| 33 | 丙戊酸質譜分析(一)：微波輔助化學標記增強丙戊酸的測定 Valproic acid analysis by mass spectrometry part I: enhanced determination of valproic acid by microwave assisted chemical labeling |
| 34 | MALDI-TOF-MS及nanoUPLC-MS/MS之簡單分析策略:分析薑黃素及ROS相關蛋白質 Simple analytical strategy for MALDI-TOF-MS and nanoUPLC-MS/MS: Quantitating curcumin in food condiments and dietary supplements and screening of acrylamide-induced ROS protein indicators reduced by curcumin |
| 35 | Ambient melamine exposure and urinary biomarkers of early renal injury. Ambient melamine exposure and urinary biomarkers of early renal injury. |
| 36 | Oxidized Metabolites of 20-Hydroxyecdysone and Their Activity on Skeletal Muscle Cells: Preparation of a Pair of Desmotropes with Opposite Bioactivities. Oxidized Metabolites of 20-Hydroxyecdysone and Their Activity on Skeletal Muscle Cells: Preparation of a Pair of Desmotropes with Opposite Bioactivities. |
| 37 | Neuroprotective effects of Hu-Yi-Neng, a diet supplement, on SH-SY5Y human neuroblastoma cells Neuroprotective effects of Hu-Yi-Neng, a diet supplement, on SH-SY5Y human neuroblastoma cells |
| 38 | Bioactive Constituents of Cirsium japonicum var. australe Bioactive Constituents of Cirsium japonicum var. australe |
| 39 | Fast quantification of S-adenosyl-L-methionine in dietary health products utilizing reversed-phase high-performance liquid chromatography: teaching an old method new tricks Fast quantification of S-adenosyl-L-methionine in dietary health products utilizing reversed-phase high-performance liquid chromatography: teaching an old method new tricks |
| 40 | In vitro anti-diabetic effect and chemical In vitro anti-diabetic effect and chemical |
| 41 | N/A Functional regulation of Alu element of human angiotensin-converting enzyme gene in neuron cells |
| 42 | An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii |
| 43 | A crossover study of noodle soup consumption in melamine bowls and total melamine excretion in urine. A crossover study of noodle soup consumption in melamine bowls and total melamine excretion in urine. |
| 44 | Can melamine levels in one-spot overnight urine specimen predict the total previous 24-hours melamine excretion in school children? Can melamine levels in one-spot overnight urine specimen predict the total previous 24-hours melamine excretion in school children? |
| 45 | Suppression of glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes. Suppression of glutamine:fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes. |
| 46 | Anti-diabetic properties of non-polar Toona sinensis Roem extract prepared by supereritieal-CO2 fluid. Anti-diabetic properties of non-polar Toona sinensis Roem extract prepared by supereritieal-CO2 fluid. |
| 47 | 2-hydroxy-4'-methoxychalcone inhibits proliferation and inflammation via peroxisome proliferator activated receptor gamma expression in human aortic smooth muscle cells. 2-hydroxy-4'-methoxychalcone inhibits proliferation and inflammation via peroxisome proliferator activated receptor gamma expression in human aortic smooth muscle cells. |
| 48 | Increased unbound retinol binding protein 4 concentration induced apoptosis through its receptor-mediated signaling. Increased unbound retinol binding protein 4 concentration induced apoptosis through its receptor-mediated signaling. |
| 49 | Isodesacetyluvaricin, an Annonaceous Acetogenin, Specifically Inhibits Gene Expression of Cyclooxygenase-2. Isodesacetyluvaricin, an Annonaceous Acetogenin, Specifically Inhibits Gene Expression of Cyclooxygenase-2. |
| 50 | Detection of melamine in a human renal uric acid stone by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Detection of melamine in a human renal uric acid stone by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). |
| 51 | Synthesis of chalcone derivatives as potential anti-diabetic agents. Synthesis of chalcone derivatives as potential anti-diabetic agents. |
| 52 | In vitro anti-diabetic activity and chemical characterization of an apolar fraction of Morus alba leaf water extract. In vitro anti-diabetic activity and chemical characterization of an apolar fraction of Morus alba leaf water extract. |
| 53 | Melamine Induces Human Renal Proximal Tubular Cell Injury via Transforming Growth Factor-Beta and Oxidative Stress. Melamine Induces Human Renal Proximal Tubular Cell Injury via Transforming Growth Factor-Beta and Oxidative Stress. |
| 54 | Chlorogenic Acid and Rutin Play a Major Role in the In Vivo Anti-Diabetic Activity of Morus alba Leaf Extract on Type II Diabetic Rats. Chlorogenic Acid and Rutin Play a Major Role in the In Vivo Anti-Diabetic Activity of Morus alba Leaf Extract on Type II Diabetic Rats. |
| 55 | Synthesis and biological evaluation of chalcone derivatives as a novel class of anti-diabetic agentsnovel class of anti-diabetic agents Synthesis and biological evaluation of chalcone derivatives as a novel class of anti-diabetic agentsnovel class of anti-diabetic agents |
| 56 | Anti-diabetic properties of non-polar toona sinensis roem extract prepared by supercritical-co2 fluid Anti-diabetic properties of non-polar toona sinensis roem extract prepared by supercritical-co2 fluid |
| 57 | 脂肪細胞內腎素與血管張力素系統調控脂肪細胞激素apelin的製造 Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes. |
| 58 | Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis. Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis. |
| 59 | Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes |
| 60 | Local action of endogenous renal tubular atrial natriuretic peptide Local action of endogenous renal tubular atrial natriuretic peptide |
| 61 | Atrial Natriuretic peptide Attenuates High Glucose-Activated Transforming Growth Factor-β, Smad and Collagen Synthesis in Renal Proximal. Atrial Natriuretic peptide Attenuates High Glucose-Activated Transforming Growth Factor-β, Smad and Collagen Synthesis in Renal Proximal. |
| 62 | Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet |
| 63 | 轉型生長因子α及表皮生長因子受器mRNA在門脈高壓鼠黏膜的表現 Expression of Transforming Growth Factor-α and Epidermal Growht Factor Receptor mRNA in the Gastric Mucosa of Portal Hypertensive Rats |
| 64 | Increased atrial natriuretic peptide mRNA expression in the kidney of diabetic rats 待補 |
Project
| NO |
YEAR — Source — No — Type
Project Name
|
Duration |
|---|---|---|
| 1 |
114 — N 國科會(原科技部) — NSTC114-2314-B-037-036 — 1 個人型
ALDH2*2等位基因促進慢性腎臟病病程發展的機制探討:轉錄體分析與治療策略開發( )
|
2025/08/01 ~ 2026/07/31 |
| 2 |
113 — N 國科會(原科技部) — MOST111-2314-B-037-073-MY3 — 1 個人型
粒線體乙醛去氫酶ALDH2*2單鹼基突變基因型對慢性腎臟病之易感性研究(3/3)( )
|
2024/08/01 ~ 2025/07/31 |
| 3 |
113 — N 國科會(原科技部) — NSTC113-2218-E-007-026 — 2 整合型
帕金森病前期精準診治智慧穿戴醫材之轉譯醫學研發:從基礎到臨床(3/3)-國立清華大學轉撥款(共同主持人:謝翠娟)( )
|
2024/08/01 ~ 2025/10/31 |
| 4 |
112 — N 國科會(原科技部) — MOST111-2314-B-037-073-MY3 — 1 個人型
粒線體乙醛去氫酶ALDH2*2單鹼基突變基因型對慢性腎臟病之易感性研究(2/3)( )
|
2023/08/01 ~ 2025/07/31 |
| 5 |
112 — N 國科會(原科技部) — NSTC112-2218-E-007-024 — 2 整合型
帕金森病前期精準診治智慧穿戴醫材之轉譯醫學研發:從基礎到臨床(2/3)-國立清華大學轉撥款(共同主持人:謝翠娟)( )
|
2023/08/01 ~ 2024/07/31 |
| 6 |
111 — N 國科會(原科技部) — MOST111-2314-B-037-073-MY3 — 1 個人型
粒線體乙醛去氫酶ALDH2*2單鹼基突變基因型對慢性腎臟病之易感性研究(1/3)( )
|
2022/08/01 ~ 2025/07/31 |
| 7 |
111 — N 國科會(原科技部) — MOST111-2314-B-037-006 — 2 整合型
新興環境污染物的共暴露對腎臟傷害之影響: 從動物及人體研究至風險評估-以鼠科動物模式探討三聚氰胺與塑化劑對腎臟傷害之累積效應(3/3)( )
|
2022/08/01 ~ 2023/07/31 |
| 8 |
111 — N 國科會(原科技部) — NSTC111-2218-E-007-019 — 2 整合型
帕金森病前期精準診治智慧穿戴醫材之轉譯醫學研發:從基礎到臨床(1/3)-國立清華大學轉撥款(共同主持人:謝翠娟)( )
|
2022/08/01 ~ 2023/07/31 |
| 9 |
110 — N 國科會(原科技部) — MOST110-2314-B-037-135 — 2 整合型
新興環境污染物的共暴露對腎臟傷害之影響: 從動物及人體研究至風險評估-以鼠科動物模式探討三聚氰胺與塑化劑對腎臟傷害之累積效應(2/3)( )
|
2021/08/01 ~ 2022/07/31 |
| 10 |
109 — N 國科會(原科技部) — MOST109-2314-B-037-068 — 2 整合型
新興環境污染物的共暴露對腎臟傷害之影響: 從動物及人體研究至風險評估-以鼠科動物模式探討三聚氰胺與塑化劑對腎臟傷害之累積效應(1/3)( )
|
2020/08/01 ~ 2021/07/31 |
| 11 |
108 — N 國科會(原科技部) — MOST107-2314-B-037-016-MY2 — 1 個人型
以調控生物節律基因為胰島素阻抗與糖尿病之治療策略：藥物篩選及機轉探討(2/2)( )
|
2019/08/01 ~ 2020/07/31 |
| 12 |
107 — N 國科會(原科技部) — MOST107-2314-B-037-016-MY2 — 1 個人型
以調控生物節律基因為胰島素阻抗與糖尿病之治療策略：藥物篩選及機轉探討(1/2)( )
|
2018/08/01 ~ 2020/07/31 |
| 13 |
106 — NK 高醫-中山合作計畫 — — 2 整合型
海洋天然物在抗糖尿病及抗肥胖之活性成分篩選及機轉探討(II)( )
|
2017/01/01 ~ 2017/12/31 |
| 14 |
106 — N 國科會(原科技部) — MOST105-2314-B-037-042-MY2 — 1 個人型
TET蛋白家族在糖尿病腎臟傷害之角色：機轉探討及預防策略開發(2/2)( )
|
2017/08/01 ~ 2018/07/31 |
| 15 |
105 — NK 高醫-中山合作計畫 — — 2 整合型
珊瑚萃取物及其衍生物抗糖尿病及抗肥胖之活性篩選及機轉探討( )
|
2016/01/01 ~ 2016/12/31 |
| 16 |
105 — N 國科會(原科技部) — MOST105-2314-B-037-042-MY2 — 1 個人型
TET蛋白家族在糖尿病腎臟傷害之角色：機轉探討及預防策略開發(1/2)( )
|
2016/08/01 ~ 2018/07/31 |
| 17 |
105 — TP 頂尖計畫(高醫) — KMU-TP105A08 —
子計畫4-1、三聚氰胺進入細胞路徑及其誘發腎臟傷害之機轉研究( )
|
2016/11/01 ~ 2017/10/31 |
| 18 |
104 — N 國科會(原科技部) — MOST104-2314-B-037-067 — 1 個人型
TET蛋白家族在代謝記憶與糖尿病腎臟病變之角色探討( )
|
2015/08/01 ~ 2016/07/31 |
| 19 |
104 — TP 頂尖計畫(高醫) — KMU-TP104A09 —
子計畫3-3、三聚氰胺暴露誘發之腎臟傷害機轉及其抗氧化天然藥物研究( )
|
2015/10/01 ~ 2016/09/30 |
| 20 |
103 — TP 頂尖計畫(高醫) — KMU-TP103A21 —
油炸食物及食用油煙中的t,t-2,4-DDE誘發代謝異常及糖尿病合併症之相關性與機轉研究(Trans, Trans-2,4-Decadiena in Frying Foods and Cooking Oil Fumes Induces Metabolic Disturbance and Diabetic Complications: Association and Mechanisms)
|
2014/08/01 ~ 2015/07/31 |
| 21 |
103 — TP 頂尖計畫(高醫) — KMU-TP103D07 —
O 位N-乙醯葡萄糖氨轉移酶與TET 蛋白家族的交互作用對代謝記憶之影響( )
|
2014/08/01 ~ 2015/07/31 |
| 22 |
103 — TP 頂尖計畫(高醫) — KMU-TP103D20 —
胰島素阻抗及糖尿病研究平台( )
|
2014/08/01 ~ 2015/07/31 |
| 23 |
102 — N 國科會(原科技部) — NSC102-2314-B-037-017 — 1 個人型
以高脂肪餵食小鼠模式探討非極性香椿葉萃取物對白色及類棕色脂肪細胞轉分化的作用與機轉( )
|
2013/08/01 ~ 2014/07/31 |
| 24 |
101 — N 國科會(原科技部) — NSC101-2314-B-037-033 — 1 個人型
非極性香椿萃取物對白色脂肪細胞轉換為類棕色指肪細胞的作用與機轉探討( )
|
2012/08/01 ~ 2013/07/31 |
| 25 |
100 — N 國科會(原科技部) — NSC98-2314-B-037-011-MY3 — 1 個人型
O-G1cNAc修飾蛋白質在人類脂肪細胞分化及脂質新生過程中之作用(3/3)( )
|
2011/08/01 ~ 2012/07/31 |
| 26 |
099 — N 國科會(原科技部) — NSC98-2314-B-037-011-MY3 — 1 個人型
O-G1cNAc修飾蛋白質在人類脂肪細胞分化及脂質新生過程中之作用(2/3)( )
|
2010/08/01 ~ 2012/07/31 |
| 27 |
098 — N 國科會(原科技部) — NSC98-2314-B-037-011-MY3 — 1 個人型
O-G1cNAc修飾蛋白質在人類脂肪細胞分化及脂質新生過程中之作用(1/3)( )
|
2009/08/01 ~ 2012/07/31 |
| 28 |
097 — N 國科會(原科技部) — NSC95-2314-B-037-094-MY3 — 1 個人型
蛋白質O-GlcNAc修飾在糖尿病腎臟病變之研究(3/3)( )
|
2008/08/01 ~ 2009/07/31 |
| 29 |
096 — N 國科會(原科技部) — NSC95-2314-B-037-094-MY3 — 1 個人型
蛋白質O-GlcNAc修飾在糖尿病腎臟病變之研究(2/3)( )
|
2007/08/01 ~ 2009/07/31 |
| 30 |
096 — N 國科會(原科技部) — NSC96-2745-B-037-002-URD — 2 整合型
提昇私校研發能量專案計畫-糖尿病併發症之分子致病機轉及治療展望(子計畫三:O-GlcNAcylation 在糖尿病大血管病變的調控及角色(3/3)( )
|
2007/08/01 ~ 2008/07/31 |
| 31 |
096 — Y 高醫-彰基合作計畫 — 97-CCH-KMU-031 — 2 整合型
發炎因子在主動脈平滑肌細胞的表現與分子調控機轉( )
|
2008/01/01 ~ 2008/12/31 |
| 32 |
095 — N 國科會(原科技部) — NSC95-2745-B-037-013-URD — 2 整合型
提昇私校研發能量專案計畫-糖尿病併發症之分子致病機轉及治療展望-子計畫三:O-GLCNACYLATION 在糖尿病大血管病變的調控及角色(2/3)( )
|
2006/08/01 ~ 2007/07/31 |
| 33 |
095 — N 國科會(原科技部) — NSC95-2314-B-037-094-MY3 — 1 個人型
蛋白質O-GLCNAC修飾在糖尿病腎臟病變之研究(1/3)( )
|
2006/08/01 ~ 2009/07/31 |
| 34 |
094 — N 國科會(原科技部) — NSC94-2314-B-037-032- — 1 個人型
O-GLcNAcylation及hexosamine biosynthetic pathway在糖尿病腎臟病變分子病理機轉中的角色( )
|
2005/08/01 ~ 2006/07/31 |
| 35 |
094 — N 國科會(原科技部) — NSC94-2745-B-037-013-URD — 2 整合型
提昇私校研發能量專案計畫-糖尿病併發症之分子致病機轉及治療展望-子計畫三:O-GlcNAcylation 在糖尿病大血管病變的調控及角色(1/3)( )
|
2005/08/01 ~ 2006/07/31 |
| 36 |
094 — QM 醫療研究計畫 — — 1 個人型
以動物模式探討新陳代謝症後群之Adipokines基因表現( )
|
2006/08/01 ~ 2007/07/31 |
Patent
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|---|---|---|---|---|
| 1 | 抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途 | 中華民國 | 2015/07/21 | I492755 |
| 2 | 用於治療糖尿病及新陳代謝的組合物及其製備方法 | 中華民國 | 2013/12/01 | I417088 |
| 3 | 用於治療動脈粥狀硬化的組合物及其製備方法 | 中華民國 | 2013/11/21 | I415600 |
| 4 | 抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途 | 世界專利(中國) | 2015/01/14 | 1567392 |
| 5 | 具生物活性之真菌組合物及其製備方法 | 中華民國 | 2015/05/11 | I483730 |
| 6 | 用於治療動脈粥狀硬化的組合物及其製備方法 | 美國 | 2018/10/16 | 10,098,853 |
| 7 | 用於治療糖尿病及新陳代謝的組合物及其製備方法 | 世界專利(美國) | 2015/07/21 | 9,085,520 |
| 8 | 用於治療代謝症候群的組合物及其製備方法 | 中華民國 | 2018/09/01 | I633880 |
| 9 | 抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途 | 美國 | 2020/06/02 | 10,668,122 |