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 Education

School — Major — Degree Duration

高雄醫學大學 — 藥學系(畢) — 博士

Doctorate, School of Pharmacy, Kaohsiung Medical University

1995/09 — 2000/06

高雄醫學院 — 藥學系(畢) — 學士

Bachelor, School of Pharmacy, Kaohsiung Medical College

1990/09 — 1994/06

 Intramural Experience

Office/Department/Institute Position Duration
藥學院 College of Pharmacy   Dean 2026/08/01 — 2029/07/31
藥學系 School of Pharmacy   Professor 2021/08/01 —  
香�菻~學系 Department of Fragrance and Cosmetic Science   Professor 2014/02/01 — 2021/07/31
香�菻~學系 Department of Fragrance and Cosmetic Science   Associate Professor 2009/09/01 — 2014/01/31
香�菻~學系 Department of Fragrance and Cosmetic Science   Assistant Professor 2003/08/01 — 2009/08/31

 Extramural Experience

DEPNO Position- Office/Department/Institute Duration
中華醫事學院化�菻~應用與管理系 助理教授 0910801 — 0920731
永達技術學院化工科 助理教授 0910201 — 0910731
樹人醫護管理專校復健科 助理教授 0900801 — 0910131

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 藥學及中醫藥 Pharmacy and Chinese Medicine and Pharmacy

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

 

 

 Area(s) of Expertise & Research

藥學、天然物化學及活性探討、香�菻~添加原料開發天然物化學,藥學,香�菻~科學

 

 Publication

NO Publication
1

Formononetin protects against oxaliplatin-induced peripheral neurotoxicity via Nrf2/HO-1 antioxidant pathway without impairing anticancer efficacy
張揚晨, 林宛萱, 柯宏慧, 羅怡卿, 張訓碩, Hui-Ching Lin, 陳宜芳* - - 1 - NeuroToxicology - NEUROTOXICOLOGY 2026 112卷(-期):103368頁
(IF: 3.8, 領域排名: 116, 領域期刊數: 356, 領域排名: 32.58%)

Formononetin protects against oxaliplatin-induced peripheral neurotoxicity via Nrf2/HO-1 antioxidant pathway without impairing anticancer efficacy
Yang-Chen Chang, Wan-Hsuan Lin, Horng-Huey Ko, Yi-Ching Lo, Hsun-Shuo Chang, Hui-Ching Lin, Yih-Fung Chen* - - 1 - NeuroToxicology - NEUROTOXICOLOGY 2026;112(-):103368
(IF: 3.8, Journal Ranking: 116, Number of Journals of this Field: 356, Ranking: 32.58%)

2

Flavonoid-rich Phyla nodiflora fraction promotes Keap1 degradation and Nrf2/HO-1 activation to attenuate particulate matter-induced oxidative stress in human keratinocytes.
林家璿, 吳瑾燁, Andrea Gu, 吳和澄, 陳宜芳*, 柯宏慧* - - 1 - Journal of Ethnopharmacology - JOURNAL OF ETHNOPHARMACOLOGY 2026 360卷(-期):121168頁
(IF: 6.8, 領域排名: 24, 領域期刊數: 285, 領域排名: 8.42%)

Flavonoid-rich Phyla nodiflora fraction promotes Keap1 degradation and Nrf2/HO-1 activation to attenuate particulate matter-induced oxidative stress in human keratinocytes.
Chia-Hsuan Lin, Jin-Ye Wu, Andrea Gu, Ho-Cheng Wu, Yih-Fung Chen*, Horng-Huey Ko* - - 1 - Journal of Ethnopharmacology - JOURNAL OF ETHNOPHARMACOLOGY 2026;360(-):121168
(IF: 6.8, Journal Ranking: 24, Number of Journals of this Field: 285, Ranking: 8.42%)

3

Medium-chain fatty acid-enabled nanostructured lipid carriers for improved β-carotene biopharmaceutical properties and antioxidant efficacy.
劉宛怡, 傅莛雯, 柯宏慧, 張立青*, 吳育澤* - - 1 - DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY - DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 2026 52卷(8期):1579–1593頁
(IF: 2.6, 領域排名: 195, 領域期刊數: 356, 領域排名: 54.78%)

Medium-chain fatty acid-enabled nanostructured lipid carriers for improved β-carotene biopharmaceutical properties and antioxidant efficacy.
Wan-Yi Liu, Ting-Wen Fu, Horng-Huey Ko, Li-Ching Chang, Yu-Tse Wu - - 1 - DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY - DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 2026;52(8):1579–1593
(IF: 2.6, Journal Ranking: 195, Number of Journals of this Field: 356, Ranking: 54.78%)

4

懸浮微粒引發之皮膚損傷:用於表皮穩態與治療標的之 AhR–Nrf2 雙途徑機制
林家璿, 顏嘉宏, 吳育澤, 張訓碩, 柯宏慧*, 陳宜芳* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2026 27卷(0期):7573頁
(IF: 5.6, 領域排名: 72, 領域期刊數: 328, 領域排名: 21.95%)

Particulate Matter-Induced Skin Injury: A Dual-Pathway AhR–Nrf2 Framework for Epidermal Homeostasis and Therapeutic Targeting
Chia-Hsuan Lin, Chia-Hung Yen, Yu-Tse Wu, Hsun-Shuo Chang, Horng-Huey Ko*, Yih-Fung Chen* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2026;27(0):7573
(IF: 5.6, Journal Ranking: 72, Number of Journals of this Field: 328, Ranking: 21.95%)

5

Sustainable extraction of bioactive compounds with antioxidant and tyrosinase inhibitory activities from Phyla nodiflora via Microwave hydrodiffusion and gravity method
劉宛怡, 蕭安凱#, 吳育澤*, 柯宏慧* - - 1 - SUSTAINABLE CHEMISTRY AND PHARMACY - SUSTAINABLE CHEMISTRY AND PHARMACY 2025 44卷(-期):101927頁
(IF: 5.8, 領域排名: 70, 領域期刊數: 376, 領域排名: 18.62%)

Sustainable extraction of bioactive compounds with antioxidant and tyrosinase inhibitory activities from Phyla nodiflora via Microwave hydrodiffusion and gravity method
Wan-Yi Liu, An-Kai Hsiao#, Yu-Tse Wu*, Horng-Huey Ko* - - 1 - SUSTAINABLE CHEMISTRY AND PHARMACY - SUSTAINABLE CHEMISTRY AND PHARMACY 2025;44(-):101927
(IF: 5.8, Journal Ranking: 70, Number of Journals of this Field: 376, Ranking: 18.62%)

6

Dual activation of AhR and Nrf2 pathways by the natural stilbenoid tapinarof protects against particulate matter-induced skin barrier dysfunction.
林家璿, 柯宏慧#, 吳瑾燁, 張訓碩, 顏嘉宏, 邱建智, 陳宜芳* - - 1 - TOXICOLOGY AND APPLIED PHARMACOLOGY - TOXICOLOGY AND APPLIED PHARMACOLOGY 2025 505卷(-期):117559頁
(IF: 3.6, 領域排名: 35, 領域期刊數: 106, 領域排名: 33.02%)

Dual activation of AhR and Nrf2 pathways by the natural stilbenoid tapinarof protects against particulate matter-induced skin barrier dysfunction.
Chia-Hsuan Lin#, Horng-Huey Ko#, Jin-Ye Wu, Hsun-Shuo Chang, Chia-Hung Yen, Chien-Chih Chiu, Yih-Fung Chen* - - 1 - TOXICOLOGY AND APPLIED PHARMACOLOGY - TOXICOLOGY AND APPLIED PHARMACOLOGY 2025;505(-):117559
(IF: 3.6, Journal Ranking: 35, Number of Journals of this Field: 106, Ranking: 33.02%)

7

Optimizing cinnamophilin delivery via SNEDDS for enhanced anti-melanogenic activity: A comprehensive evaluation of skin safety, permeability, and tyrosinase inhibition
陳禹臻, 陳宜芳, 游新雅, 林家璿#, 劉宛怡#, 張訓碩, 吳育澤*, 柯宏慧* - - 1 - INTERNATIONAL JOURNAL OF PHARMACEUTICS - INTERNATIONAL JOURNAL OF PHARMACEUTICS 2025 685卷(-期):126260頁
(IF: 5.2, 領域排名: 43, 領域期刊數: 352, 領域排名: 12.22%)

Optimizing cinnamophilin delivery via SNEDDS for enhanced anti-melanogenic activity: A comprehensive evaluation of skin safety, permeability, and tyrosinase inhibition
Yu-Chen Chen, Yih-Fung Chen, Hsin-Ya Yu, Chia-Hsuan Lin#, Wan-Yi Liu#, Hsun-Shuo Chang, Yu-Tse Wu*, Horng-Huey Ko* - - 1 - INTERNATIONAL JOURNAL OF PHARMACEUTICS - INTERNATIONAL JOURNAL OF PHARMACEUTICS 2025;685(-):126260
(IF: 5.2, Journal Ranking: 43, Number of Journals of this Field: 352, Ranking: 12.22%)

8

Formononetin 透過 Nrf2/HO-1 抗氧化途徑保護免於草酸鉑所致的周邊神經毒性且不影響其抗癌療效
張揚晨, 林宛萱, 柯宏慧, 羅怡卿, 張訓碩, 林惠菁, 陳宜芳 - - 1 - NEUROTOXICOLOGY - NEUROTOXICOLOGY 2025 112卷(-期):103368頁
(IF: 3.9, 領域排名: 88, 領域期刊數: 352, 領域排名: 25.00%)

Formononetin protects against oxaliplatin-induced peripheral neurotoxicity via Nrf2/HO-1 antioxidant pathway without impairing anticancer efficacy.
Yang-Chen Chang, Wan-Hsuan Lin, Horng-Huey Ko, Yi-Ching Lo, Hsun-Shuo Chang, Hui-Ching Lin, Yih-Fung Chen - - 1 - NEUROTOXICOLOGY - NEUROTOXICOLOGY 2025;112(-):103368
(IF: 3.9, Journal Ranking: 88, Number of Journals of this Field: 352, Ranking: 25.00%)

9

芳樟醇,一種植物芳香化合物,在帕金森氏症實驗模型中具保護多巴胺神經元及改善運動功能和骨骼肌強度的作用
張婉萱, 許弘德#, 林志晟, 安麗梅, 李建興, 柯宏慧, 林志隆, 羅怡卿* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024 25卷(5期):2514頁
(IF: 4.9, 領域排名: 66, 領域期刊數: 313, 領域排名: 21.09%)

Linalool, a Fragrance Compound in Plants, Protects Dopaminergic Neurons and Improves Motor Function and Skeletal Muscle Strength in Experimental Models of Parkinson's Disease.
Wan-Hsuan Chang, Hung-Te Hsu#, Chih-Cheng Lin, Li-Mei An, Chien-Hsing Lee, Horng-Huey Ko, Chih-Lung Lin, Yi-Ching Lo* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024;25(5):2514
(IF: 4.9, Journal Ranking: 66, Number of Journals of this Field: 313, Ranking: 21.09%)

10

Formulation Approaches to Crystalline Status Modification for Carotenoids: Impacts on Dissolution, Stability, Bioavailability, and Bioactivities
劉宛怡#, 謝昀珊#, 柯宏慧*, 吳育澤* - - 1 - Pharmaceutics - PHARMACEUTICS 2023 15卷(2期):485頁
(IF: 5.4, 領域排名: 50, 領域期刊數: 278, 領域排名: 17.99%)

Formulation Approaches to Crystalline Status Modification for Carotenoids: Impacts on Dissolution, Stability, Bioavailability, and Bioactivities
Wan-Yi Liu, Yun-Shan Hsieh, Horng-Huey Ko*, Yu-Tse Wu* - - 1 - Pharmaceutics - PHARMACEUTICS 2023;15(2):485
(IF: 5.4, Journal Ranking: 50, Number of Journals of this Field: 278, Ranking: 17.99%)

11

Chemical investigations and cytotoxic effects of metabolites from Antrodia camphorata against human hepatocellular carcinoma cells.
陳宜芳, 吳和澄, 張家銘, 柯宏慧, 林居宏, 張訓碩* - - 1 - NATURAL PRODUCT RESEARCH - NATURAL PRODUCT RESEARCH 2023 37卷(4期):560-570頁
(IF: 2.2, 領域排名: 40, 領域期刊數: 73, 領域排名: 54.79%)

Chemical investigations and cytotoxic effects of metabolites from Antrodia camphorata against human hepatocellular carcinoma cells.
Yih-Fung Chen, Ho-Cheng Wu, Jia-Min Chang, Horng-Huey Ko, Chu-Hung Lin , Hsun-Shuo Chang* - - 1 - NATURAL PRODUCT RESEARCH - NATURAL PRODUCT RESEARCH 2023;37(4):560-570
(IF: 2.2, Journal Ranking: 40, Number of Journals of this Field: 73, Ranking: 54.79%)

12

Chemical constituents with anti-lipid droplet accumulation and anti-inflammatory activity from Elaeagnus glabra
鄭如芯, 吳和澄, 顏嘉宏, 黃聰龍, 柯宏慧, 張訓碩* - - 1 - Plants - PLANTS-BASEL 2023 12卷(16期):2943頁
(IF: 4.5, 領域排名: 43, 領域期刊數: 239, 領域排名: 17.99%)

Chemical constituents with anti-lipid droplet accumulation and anti-inflammatory activity from Elaeagnus glabra
Ju-Hsin Cheng, Ho-Cheng Wu, Chia-Hung Yen, Tsong-Long Hwang, Horng-Huey Ko, Hsun-Shuo Chang* - - 1 - Plants - PLANTS-BASEL 2023;12(16):2943
(IF: 4.5, Journal Ranking: 43, Number of Journals of this Field: 239, Ranking: 17.99%)

13

Anti-Inflammatory Effects of Cycloheterophyllin on Dinitrochlorobenzene-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice
C. C. Wang, C. Y. Hsiao, Y. J. Hsu,柯宏慧, D. C. Chang, C. F. Hung* - - 1 - Molecules - MOLECULES 2022 27卷(9期):2610頁
(IF: 4.927, 領域排名: 65, 領域期刊數: 179, 領域排名: 36.31%)

Anti-Inflammatory Effects of Cycloheterophyllin on Dinitrochlorobenzene-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice
C. C. Wang, C. Y. Hsiao, Y. J. Hsu, H. H. Ko, D. C. Chang, C. F. Hung* - - 1 - Molecules - MOLECULES 2022;27(9):2610
(IF: 4.927, Journal Ranking: 65, Number of Journals of this Field: 179, Ranking: 36.31%)

14

Seco-abietanoids from Cryptomeria japonica and their inhibitory activity toward xanthine oxidase
C. I Chang, C. C. Chen, 柯宏慧, J. J. Chen, M. J. Cheng, C. Y. Chao*, Y. H. Kuo* - - 1 - Chem. Nat. Compd. - CHEMISTRY OF NATURAL COMPOUNDS 2022 58卷(3期):478-481頁
(IF: 0.83, 領域排名: 50, 領域期刊數: 56, 領域排名: 89.29%)

Seco-abietanoids from Cryptomeria japonica and their inhibitory activity toward xanthine oxidase
C. I Chang, C. C. Chen, H. H. Ko, J. J. Chen, M. J. Cheng, C. Y. Chao*, Y. H. Kuo* - - 1 - Chem. Nat. Compd. - CHEMISTRY OF NATURAL COMPOUNDS 2022;58(3):478-481
(IF: 0.83, Journal Ranking: 50, Number of Journals of this Field: 56, Ranking: 89.29%)

15

Undescribed alkyne-geranylcyclohexenetriols from the endophyte Diaporthe caulivora 09F0132 and their anti-melanogenic activity.
楊舜心, 陳宜芳, 柯宏慧, 吳和澄, Sung-Yuan Hsieh, Ming-Der Wu, 鄭銘仁*, 張訓碩* - - 1 - PHYTOCHEMISTRY - PHYTOCHEMISTRY 2022 202卷(-期):113312頁
(IF: 4.004, 領域排名: 53, 領域期刊數: 238, 領域排名: 22.27%)

Undescribed alkyne-geranylcyclohexenetriols from the endophyte Diaporthe caulivora 09F0132 and their anti-melanogenic activity.
Shuen-Shin Yang, Yih-Fung Chen, Horng-Huey Ko, Ho-Cheng Wu, Sung-Yuan Hsieh, Ming-Der Wu, Ming-Jen Cheng*, Hsun-Shuo Chang* - - 1 - PHYTOCHEMISTRY - PHYTOCHEMISTRY 2022;202(-):113312
(IF: 4.004, Journal Ranking: 53, Number of Journals of this Field: 238, Ranking: 22.27%)

16

山菅蘭成分中的酪胺酸酶抑制劑
陳昱璋, Sheng-Han Su, Jheng-Cian Huang, Che-Yi Chao, 宋秉鈞, 陳宜芳, 柯宏慧*, Yueh-Hsiung Kuo* - - 1 - Plants (Basel) - PLANTS-BASEL 2022 11卷(16期):2142頁
(IF: 4.658, 領域排名: 39, 領域期刊數: 238, 領域排名: 16.39%)

Tyrosinase Inhibitors Derived from Chemical Constituents of Dianella ensifolia
Yu-Chang Chen, Sheng-Han Su, Jheng-Cian Huang, Che-Yi Chao, Ping-Jyun Sung, Yih-Fung Chen, Horng-Huey Ko*, Yueh-Hsiung Kuo* - - 1 - Plants (Basel) - PLANTS-BASEL 2022;11(16):2142
(IF: 4.658, Journal Ranking: 39, Number of Journals of this Field: 238, Ranking: 16.39%)

17

Preparatory Conditions Optimization and Characterization of Hierarchical Porous Carbon from Seaweed as Carbon-Precursor Using a Box—Behnken Design for Application of Supercapacitor
Wein-Duo Yang*, Jing-Xuan Wang, 吳育澤, 張訓碩, 柯宏慧 - - 1 - Materials - MATERIALS 2022 15卷(16期):5748頁
(IF: 3.748, 領域排名: 28, 領域期刊數: 69, 領域排名: 40.58%)

Preparatory Conditions Optimization and Characterization of Hierarchical Porous Carbon from Seaweed as Carbon-Precursor Using a Box—Behnken Design for Application of Supercapacitor
Wein-Duo Yang*, Jing-Xuan Wang, Yu-TseWu, Hsun-Shuo Chang, Horng-Huey Ko - - 1 - Materials - MATERIALS 2022;15(16):5748
(IF: 3.748, Journal Ranking: 28, Number of Journals of this Field: 69, Ranking: 40.58%)

18

Albanin A, Derived from the Root Bark of Morus alba L., Depresses Glutamate Release in the Rat Cerebrocortical Nerve Terminals via Ca2+/Calmodulin/Adenylate Cyclase 1 Suppression
Y.Chang,C.F.Hung,H.H.Ko柯宏慧,S.J.Wang* - - 1 - JOURNAL OF MEDICINAL FOOD - JOURNAL OF MEDICINAL FOOD 2021 24卷(3期):209217頁
(IF: 2.542, 領域排名: 97, 領域期刊數: 143, 領域排名: 67.83%)

Albanin A, Derived from the Root Bark of Morus alba L., Depresses Glutamate Release in the Rat Cerebrocortical Nerve Terminals via Ca2+/Calmodulin/Adenylate Cyclase 1 Suppression
Y. Chang, C. F. Hung, H. H. Ko, S. J. Wang* - - 1 - JOURNAL OF MEDICINAL FOOD - JOURNAL OF MEDICINAL FOOD 2021;24(3):209217
(IF: 2.542, Journal Ranking: 97, Number of Journals of this Field: 143, Ranking: 67.83%)

19

Oenothera laciniata Hill Extracts Exhibits Antioxidant Effects and Attenuates Melanogenesis in B16-F10 Cells via Downregulating CREB/MITF/Tyrosinase and Upregulating p-ERK and p-JNK.
柯宏慧, Yeo-Tzu Chang, Yueh-Hsiung Kuo, 林家璿, 陳宜芳* - - 1 - Plants (Basel, Switzerland) - PLANTS-BASEL 2021 10卷(4期):727頁
(IF: 4.658, 領域排名: 39, 領域期刊數: 238, 領域排名: 16.39%)

Oenothera laciniata Hill Extracts Exhibits Antioxidant Effects and Attenuates Melanogenesis in B16-F10 Cells via Downregulating CREB/MITF/Tyrosinase and Upregulating p-ERK and p-JNK.
Horng-Huey Ko (柯宏慧), Yeo-Tzu Chang, Yueh-Hsiung Kuo, Chia-Hsuan Lin (林家璿), Yih-Fung Chen (陳宜芳)* - - 1 - Plants (Basel, Switzerland) - PLANTS-BASEL 2021;10(4):727
(IF: 4.658, Journal Ranking: 39, Number of Journals of this Field: 238, Ranking: 16.39%)

20

Inhibition of UVA Damage on Human Skin Dermis Fibroblasts by the Isoflavonoid Intermediate Deoxybenzoin-3A
Hsun-Hao Chang, 柯宏慧, Tzy-Ming Lu, Jia-Ying Lin, Der-Chen Chang, Thomas W Chu*, Chi-Feng Hung* - - 1 - Chem. Res. Toxicol. - CHEMICAL RESEARCH IN TOXICOLOGY 2021 34卷(4期):1133-1139頁
(IF: 3.973, 領域排名: 35, 領域期刊數: 94, 領域排名: 37.23%)

Inhibition of UVA Damage on Human Skin Dermis Fibroblasts by the Isoflavonoid Intermediate Deoxybenzoin-3A
Hsun-Hao Chang, Horng-Huey Ko, Tzy-Ming Lu, Jia-Ying Lin, Der-Chen Chang, Thomas W Chu*, Chi-Feng Hung* - - 1 - Chem. Res. Toxicol. - CHEMICAL RESEARCH IN TOXICOLOGY 2021;34(4):1133-1139
(IF: 3.973, Journal Ranking: 35, Number of Journals of this Field: 94, Ranking: 37.23%)

21

Eupafolin Suppresses P/Q-Type Ca 2+ Channels to Inhibit Ca 2+/ Calmodulin-Dependent Protein Kinase II and Glutamate Release at Rat Cerebrocortical Nerve Terminals
A. Chang, C. F. Hung, P. W. Hsieh, 柯宏慧, S. J. Wang* - - 1 - Biomol. Ther. - BIOMOLECULES & THERAPEUTICS 2021 29卷(6期):630-636頁
(IF: 4.231, 領域排名: 106, 領域期刊數: 279, 領域排名: 37.99%)

Eupafolin Suppresses P/Q-Type Ca 2+ Channels to Inhibit Ca 2+/ Calmodulin-Dependent Protein Kinase II and Glutamate Release at Rat Cerebrocortical Nerve Terminals
A. Chang, C. F. Hung, P. W. Hsieh, H. H. Ko, S. J. Wang* - - 1 - Biomol. Ther. - BIOMOLECULES & THERAPEUTICS 2021;29(6):630-636
(IF: 4.231, Journal Ranking: 106, Number of Journals of this Field: 279, Ranking: 37.99%)

22

Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima
Chu-Hung Lin, Hsiao-Jung Chou, Chih-Chi Chang, 陳益昇, 張訓碩, 鄭天祿, Yueh-Hsiung Kuo*, 柯宏慧* - - 1 - Molecules - MOLECULES 2020 25卷(21期):5170頁
(IF: 4.411, 領域排名: 63, 領域期刊數: 179, 領域排名: 35.20%)

Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima
Chu-Hung Lin, Hsiao-Jung Chou, Chih-Chi Chang, Ih-Sheng Chen, Hsun-Shuo Chang, Tian-Lu Cheng, Yueh-Hsiung Kuo*, Horng-Huey Ko* - - 1 - Molecules - MOLECULES 2020;25(21):5170
(IF: 4.411, Journal Ranking: 63, Number of Journals of this Field: 179, Ranking: 35.20%)

23

Biotransformation of ganoderic acid A to 3-O-acetyl ganoderic acid A by soil-isolated Streptomyces sp.
張德生*,柯宏慧,T. Y. Wang, C. H. Lee, J. Y. Wu * - - 9 - Fermentation - FERMENTATION-BASEL 2018 4卷(0期):101頁
(IF: 5.123, 領域排名: 44, 領域期刊數: 158, 領域排名: 27.85%)

Biotransformation of ganoderic acid A to 3-O-acetyl ganoderic acid A by soil-isolated Streptomyces sp.
T. S. Chang *, H. H. Ko, T. Y. Wang, C. H. Lee, J. Y. Wu * - - 9 - Fermentation - FERMENTATION-BASEL 2018;4(0):101
(IF: 5.123, Journal Ranking: 44, Number of Journals of this Field: 158, Ranking: 27.85%)

24

Mechanism of lakoochin A inducing apoptosis of A375.S2 melanoma cells through mitochondrial ROS and MAPKs pathway.
K. T. Peng; Y. C. Chiang; 柯宏慧; P. L. Chi; C. L. Tsai; M. I Ko; M. H. Lee; L. F. Hsu*; and 李江文* - - 1 - Intenational Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018 19卷(9期):2649頁
(IF: 3.687, 領域排名: 90, 領域期刊數: 293, 領域排名: 30.72%)

Mechanism of lakoochin A inducing apoptosis of A375.S2 melanoma cells through mitochondrial ROS and MAPKs pathway.
K. T. Peng, Y. C. Chiang, H. H. Ko, P. L. Chi, C. L. Tsai, M. I Ko, M. H. Lee, L. F. Hsu*, and C. W. Lee* - - 1 - Intenational Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018;19(9):2649
(IF: 3.687, Journal Ranking: 90, Number of Journals of this Field: 293, Ranking: 30.72%)

25

Cyclocommunol induces apoptosis in human oral squamous cell carcinoma partially through a Mcl-1-dependent mechanism.
翁靖如*; L. Y. Bai; 柯宏慧; Y. T. Tsai - - 1 - Phytomedicine - PHYTOMEDICINE 2018 39卷(-期):25-32頁
(IF: 3.61, 領域排名: 2, 領域期刊數: 27, 領域排名: 7.41%)

Cyclocommunol induces apoptosis in human oral squamous cell carcinoma partially through a Mcl-1-dependent mechanism.
J. R. Weng* , L. Y. Bai , H. H. Ko , Y. T. Tsai - - 1 - Phytomedicine - PHYTOMEDICINE 2018;39(-):25-32
(IF: 3.61, Journal Ranking: 2, Number of Journals of this Field: 27, Ranking: 7.41%)

26

Densification and biocompatibility of sintering 3.0 mol% yttria- tetragonal ZrO2 polycrystal ceramics with x wt% Fe2O3 and 5.0 wt% mica powders additive.
C.L. Wang,藍鼎勛, C.W. Tzeng, C.C. Chang,T.C. Lin,柯宏慧*,W.S. Hwang,H.H. Huang,顏峰霖,王木琴* - - 1 - Ceram. Int. - Ceram. Int. 2017 43卷(0期):1809頁
(IF: 3.057, 領域排名: 2, 領域期刊數: 27, 領域排名: 7.41%)

Densification and biocompatibility of sintering 3.0 mol% yttria- tetragonal ZrO2 polycrystal ceramics with x wt% Fe2O3 and 5.0 wt% mica powders additive.
C.L. Wang, T.H. Lan, C.W. Tzeng, C.C. Chang, T.C. Lin, H.H. Ko*, W.S. Hwang, H.H. Huang, F.L. Yen, M.C. Wang* - - 1 - Ceram. Int. - Ceram. Int. 2017;43(0):1809
(IF: 3.057, Journal Ranking: 2, Number of Journals of this Field: 27, Ranking: 7.41%)

27

Synthesis and optical properties of Mg-Al layered double hydroxides precursor powders
林家璿, 朱學良, 黃文星, 王木琴*, 柯宏慧* - - 1 - AIP Adavnce - AIP ADV 2017 7卷(0期):125005頁
(IF: 1.653, 領域排名: 81, 領域期刊數: 146, 領域排名: 55.48%)

Synthesis and optical properties of Mg-Al layered double hydroxides precursor powders
Chia-Hsuan Lin, Hsueh-Liang Chu, Weng-Sing Hwang, Moo-Chin Wang*, Horng-Huey Ko* - - 1 - AIP Adavnce - AIP ADV 2017;7(0):125005
(IF: 1.653, Journal Ranking: 81, Number of Journals of this Field: 146, Ranking: 55.48%)

28

Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation
Lee, CW; 顏峰霖(Yen FL); 柯宏慧(Ko, HH); Li, SY; Chiang, YC; Lee, MH; Tsai, MH; Hsu, LF - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Int J Mol Sci. 2017 18卷(7期):E1508頁
(IF: 3.687, 領域排名: 90, 領域期刊數: 292, 領域排名: 30.82%)

Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation
- - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Int J Mol Sci. 2017;18(7):E1508
(IF: 3.687, Journal Ranking: 90, Number of Journals of this Field: 292, Ranking: 30.82%)

29

Two new sesquarterpenoids from the bark of Cryptomeria japonica.
C. I Chang, S. Y. Wang, M. D. Wu, M. J. Cheng, H. H. Ko(柯宏慧), H. S. Chang(張訓碩), J. J. Chen, C. C. Chenka, Y. H. Kuo* - - 1 - Phytochemistry Letters - 2017 22卷(0期):56-60頁
(IF: 1.575, 領域排名: 95, 領域期刊數: 222, 領域排名: 42.79%)

Two new sesquarterpenoids from the bark of Cryptomeria japonica.
C. I Chang, S. Y. Wang, M. D. Wu, M. J. Cheng, H. H. Ko(柯宏慧), H. S. Chang(張訓碩), J. J. Chen, C. C. Chenka, Y. H. Kuo* - - 1 - Phytochemistry Letters - 2017;22(0):56-60
(IF: 1.575, Journal Ranking: 95, Number of Journals of this Field: 222, Ranking: 42.79%)

30

Crystallization kinetics evaluated by the modified formula and optical properties of CdO and ZnO in 0.5ZnO-0.5CdO thin films.
B. Huang, H. L. Chu, M. C. Wang(王木琴)*, C. L. Wang, W. S. Hwang, C. Liu, H. H. Ko(柯宏慧), X. Zhao* - - 1 - Journal of Alloys and Compounds - J. Alloys Compd. 2017 43卷(0期):1809-1818頁
(IF: 3.779, 領域排名: 4, 領域期刊數: 75, 領域排名: 5.33%)

Crystallization kinetics evaluated by the modified formula and optical properties of CdO and ZnO in 0.5ZnO-0.5CdO thin films.
B. Huang, H. L. Chu, M. C. Wang*, C. L. Wang, W. S. Hwang, C. Liu, H. H. Ko, X. Zhao* - - 1 - Journal of Alloys and Compounds - J. Alloys Compd. 2017;43(0):1809-1818
(IF: 3.779, Journal Ranking: 4, Number of Journals of this Field: 75, Ranking: 5.33%)

31

Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress
林資展,李江文,胡楚松*, 顏峰霖* - - 1 - International Journal of Nanomedicine - INT J NANOMED 2016 11卷(-期):3907-3926頁
(IF: 4.32, 領域排名: 41, 領域期刊數: 255, 領域排名: 16.08%)

Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress
Zih-Chan Lin, Chiang-Wen Lee, Ming-Horng Tsai, Horng-Huey Ko, Jia-You Fang, Yao-Chang Chiang, Chan-Jung Liang, Lee-Fen Hsu, Stephen Chu-Sung Hu*, Feng-Lin Yen*. - - 1 - International Journal of Nanomedicine - INT J NANOMED 2016;11(-):3907-3926
(IF: 4.32, Journal Ranking: 41, Number of Journals of this Field: 255, Ranking: 16.08%)

32

Three New Abietane-type Diterpenes from the Bark of Cryptomeria japonica.
Chi-I Chang, Chien-Chih Chen, Sheng-Yang Wang, Che-Yi Chao, Louis Kuoping Chao, Jih-Jung Chen, 柯宏慧*, Cheng-Chi Chen*, and Yueh-Hsiung Kuo* - - 1 - Helv. Chim. Acta - Helv. Chim. Acta 2016 99卷(0期):710-715頁
(IF: 1.071, 領域排名: 120, 領域期刊數: 166, 領域排名: 72.29%)

Three New Abietane-type Diterpenes from the Bark of Cryptomeria japonica.
Chi-I Chang, Chien-Chih Chen, Sheng-Yang Wang, Che-Yi Chao, Louis Kuoping Chao, Jih-Jung Chen, Horng-Huey Ko*, Cheng-Chi Chen*, and Yueh-Hsiung Kuo* - - 1 - Helv. Chim. Acta - Helv. Chim. Acta 2016;99(0):710-715
(IF: 1.071, Journal Ranking: 120, Number of Journals of this Field: 166, Ranking: 72.29%)

33

Kinetics of Anatase Transition to Rutile TiO2 from Titanium Dioxide Precursor Powders Synthesized by a Sol-gel Process.
王程勵,黃文星,朱學良,林惠娟,柯宏慧*,王木琴* - - 0 - Ceramics International - Ceram. Int 2016 42卷(0期):13136-13143頁
(IF: 2.986, 領域排名: 2, 領域期刊數: 26, 領域排名: 7.69%)

Kinetics of Anatase Transition to Rutile TiO2 from Titanium Dioxide Precursor Powders Synthesized by a Sol-gel Process.
C. L. Wang, W. S. Hwang, H. L. Chu, H. J. Lin, H. H. Ko*, and M. C. Wang* - - 0 - Ceramics International - Ceram. Int 2016;42(0):13136-13143
(IF: 2.986, Journal Ranking: 2, Number of Journals of this Field: 26, Ranking: 7.69%)

34

A New Anthraquinone Glycoside from Rhamnus nakaharai and Anti-tyrosinase Effect of 6-Methoxysorigenin.
T. M. Lu*,柯宏慧 - - 1 - Natural Product Research - Nat. Prod. Res 2016 30卷(23期):2655-2661頁
(IF: 1.828, 領域排名: 29, 領域期刊數: 40, 領域排名: 72.50%)

A New Anthraquinone Glycoside from Rhamnus nakaharai and Anti-tyrosinase Effect of 6-Methoxysorigenin.
T. M. Lu* and H. H. Ko - - 1 - Natural Product Research - Nat. Prod. Res 2016;30(23):2655-2661
(IF: 1.828, Journal Ranking: 29, Number of Journals of this Field: 40, Ranking: 72.50%)

35

Phase formation mechanism of the zinc titanate precursor powders prepared at various pH using a hydrothermal process
C.L. Wang, H.L. Chu, 柯宏慧, C.S. Hsi, W.L. Li, W.S. Hwang, K.M. Chang, 王木琴* - - 1 - Ceramics International - Ceram. Inter. 2015 41卷(2期):2028-2041頁
(IF: 2.758, 領域排名: 3, 領域期刊數: 27, 領域排名: 11.11%)

Phase formation mechanism of the zinc titanate precursor powders prepared at various pH using a hydrothermal process
C.L. Wang, H.L. Chu, H.H. Ko, C.S. Hsi, W.L. Li, W.S. Hwang, K.M. Chang, M.C. Wang* - - 1 - Ceramics International - Ceram. Inter. 2015;41(2):2028-2041
(IF: 2.758, Journal Ranking: 3, Number of Journals of this Field: 27, Ranking: 11.11%)

36

Biological evaluation of secondary metabolites from the root of Machilus obovatifolia
林珊瑜, 柯宏慧, Shiow-Ju Lee, 張訓碩*, Chu-Hung Lin, 陳益昇* - - 1 - Chemistry & Biodiversity - Chem. & Biodivers. 2015 12卷(7期):1057-1067頁
(IF: 1.444, 領域排名: 90, 領域期刊數: 163, 領域排名: 55.21%)

Biological evaluation of secondary metabolites from the root of Machilus obovatifolia
Shan-Yu Lin, Horng-Huey Ko, Shiow-Ju Lee, Hsun-Shuo Chang*, Chu-Hung Lin, Ih-Sheng Chen* - - 1 - Chemistry & Biodiversity - Chem. & Biodivers. 2015;12(7):1057-1067
(IF: 1.444, Journal Ranking: 90, Number of Journals of this Field: 163, Ranking: 55.21%)

37

New furanone and sesquiterpene from the pericarp of Calocedrus formosana
Tzong-Huei Lee, Ming-Shian Lee, 柯宏慧, Jih-Jung Chen, 張訓碩, Mei-Hwei Tseng, Sheng-Yang Wang, Chien-Chih Chen, Yueh-Hsiung Kuo* - - 1 - Natural Product Communications - Nat. Prod. Commun. 2015 10卷(6期):845-846頁
(IF: 0.908, 領域排名: 76, 領域期刊數: 123, 領域排名: 61.79%)

New furanone and sesquiterpene from the pericarp of Calocedrus formosana
Tzong-Huei Lee, Ming-Shian Lee, Horng-Huey Ko, Jih-Jung Chen, Hsun-Shuo Chang, Mei-Hwei Tseng, Sheng-Yang Wang, Chien-Chih Chen, Yueh-Hsiung Kuo* - - 1 - Natural Product Communications - Nat. Prod. Commun. 2015;10(6):845-846
(IF: 0.908, Journal Ranking: 76, Number of Journals of this Field: 123, Ranking: 61.79%)

38

Chemical Constituents Derived from Artocarpus xanthocarpus as Inhibitors of Melanin Biosynthesis
金語菁, 林家琪, 盧梓銘, 李志��,陳益昇, 郭悅雄, 柯宏慧* - - 1 - Phytochemistry - Phytochemistry 2015 117卷(7期):424-435頁
(IF: 2.779, 領域排名: 44, 領域期刊數: 209, 領域排名: 21.05%)

Chemical Constituents Derived from Artocarpus xanthocarpus as Inhibitors of Melanin Biosynthesis
Y. J. Jin, C. C. Lin, T. M. Lu, J. H. Li, I. S. Chen, Y. H Kuo, and H. H. Ko* - - 1 - Phytochemistry - Phytochemistry 2015;117(7):424-435
(IF: 2.779, Journal Ranking: 44, Number of Journals of this Field: 209, Ranking: 21.05%)

39

Free Radical Scavenging, Anti-tyrosinase and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavonoes
T. M. Lu*, 柯宏慧, L. T. Ng, Y. P. Hsieh - - 1 - CHEMISTRY & BIODIVERSITY - Chem. Biodivers 2015 6卷(0期):963-979頁
(IF: 1.444, 領域排名: 90, 領域期刊數: 163, 領域排名: 55.21%)

Free Radical Scavenging, Anti-tyrosinase and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavonoes
T. M. Lu*, H. H. Ko, L. T. Ng, Y. P. Hsieh - - 1 - CHEMISTRY & BIODIVERSITY - Chem. Biodivers 2015;6(0):963-979
(IF: 1.444, Journal Ranking: 90, Number of Journals of this Field: 163, Ranking: 55.21%)

40

Phase transformation and microstructure of Zn2Ti3O8 nanocrystallite powders prepared using the hydrothermal process
王程勵, 黃文星, 柯宏慧*, 許志雄, 張國明, 王木琴* - - 1 - Metallurgical and Materials Transactions A - METALL MATER TRANS A 2014 45卷(1期):250-260頁
(IF: 1.627, 領域排名: 10, 領域期刊數: 76, 領域排名: 13.16%)

Phase transformation and microstructure of Zn2Ti3O8 nanocrystallite powders prepared using the hydrothermal process
C.L. Wang, W.S. Hwang, H.H. Ko*, C.S. Hsi, K.M. Chang, M.C. Wang* - - 1 - Metallurgical and Materials Transactions A - METALL MATER TRANS A 2014;45(1):250-260
(IF: 1.627, Journal Ranking: 10, Number of Journals of this Field: 76, Ranking: 13.16%)

41

Thermal behavior and phase transformation of TiO2 nanocrystallites prepared by a coprecipitation route
葉上暐, 陳彥伶, 許志雄, 柯宏慧, 王木琴* - - 1 - Metallurgical and Materials Transactions A - METALL MATER TRANS A 2014 45卷(1期):261-268頁
(IF: 1.874, 領域排名: 16, 領域期刊數: 74, 領域排名: 21.62%)

Thermal behavior and phase transformation of TiO2 nanocrystallites prepared by a coprecipitation route
S.W. Yeh, Y.L. Chen, C.S. Hsi, H.H. Ko, M.C. Wang* - - 1 - Metallurgical and Materials Transactions A - METALL MATER TRANS A 2014;45(1):261-268
(IF: 1.874, Journal Ranking: 16, Number of Journals of this Field: 74, Ranking: 21.62%)

42

Crystallite growth kinetics of TiO2 surface modification with 9 mol% ZnO prepared by a coprecipitation process
柯宏慧, 許志雄, 王木琴*, 趙修健 - - 1 - Journal of Alloys and Compounds - J ALLOY COMPD 2014 588卷(0期):428-439頁
(IF: 3.133, 領域排名: 5, 領域期刊數: 74, 領域排名: 6.76%)

Crystallite growth kinetics of TiO2 surface modification with 9 mol% ZnO prepared by a coprecipitation process
H.H. Ko, C.S. Hsi, M.C. Wang*, X. Zhao - - 1 - Journal of Alloys and Compounds - J ALLOY COMPD 2014;588(0):428-439
(IF: 3.133, Journal Ranking: 5, Number of Journals of this Field: 74, Ranking: 6.76%)

43

Growth and optical properties of cerium dioxide nanocrystallites prepared by coprecipitation routes
柯宏慧,楊國麗,鄭慧如,王木琴*,趙修健 - - 1 - Ceramics International - CERAM INT 2014 40卷(3期):4055–4064頁
(IF: 2.986, 領域排名: 2, 領域期刊數: 26, 領域排名: 7.69%)

Growth and optical properties of cerium dioxide nanocrystallites prepared by coprecipitation routes
H.H. Ko, G.L. Yang, H.Z. Cheng, M.C. Wang*, X. Zhao - - 1 - Ceramics International - CERAM INT 2014;40(3):4055–4064
(IF: 2.986, Journal Ranking: 2, Number of Journals of this Field: 26, Ranking: 7.69%)

44

Eupafolin, a skin whitening flavonoid isolated from Phyla nodiflora, downregulated melanogenesis: Role of MAPK and Akt pathways
柯宏慧, Y.C. Chiang, M.H. Tsai, C.J. Liang, L.F. Hsu, S.Y. Li, 王木琴, 顏峰霖*, C.W. Lee - - 1 - Journal of Ethnopharmacology - 2014 151卷(1期):386-393頁
(IF: 2.998, 領域排名: 3, 領域期刊數: 24, 領域排名: 12.50%)

Eupafolin, a skin whitening flavonoid isolated from Phyla nodiflora, downregulated melanogenesis: Role of MAPK and Akt pathways
H.H. Ko, Y.C. Chiang, M.H. Tsai, C.J. Liang, L.F. Hsu, S.Y. Li, M.C. Wang, F.L. Yen, C.W. Lee - - 1 - Journal of Ethnopharmacology - 2014;151(1):386-393
(IF: 2.998, Journal Ranking: 3, Number of Journals of this Field: 24, Ranking: 12.50%)

45

Phase formation of zinc titanate precursor powders prepared by a hydrothermal process in various pH environments
C.-L. Wang, W.-S. Hwang, H.-L. Chu, 柯宏慧*, C.-S. Hsi, W.-L. Li, K.-M. Chang, 王木琴* - - 1 - Metallurgical and Materials Transactions A - METALL MATER TRANS A 2014 45A卷(4期):2689-2698頁
(IF: 1.874, 領域排名: 16, 領域期刊數: 74, 領域排名: 21.62%)

Phase formation of zinc titanate precursor powders prepared by a hydrothermal process in various pH environments
C.-L. Wang, W.-S. Hwang, H.-L. Chu, H.-H. Ko*, C.-S. Hsi, W.-L. Li, K.-M. Chang, M.-C. Wang* - - 1 - Metallurgical and Materials Transactions A - METALL MATER TRANS A 2014;45A(4):2689-2698
(IF: 1.874, Journal Ranking: 16, Number of Journals of this Field: 74, Ranking: 21.62%)

46

Biological Evaluation of Secondary Metabolites from the Roots of Myrica adenophora
丁雅智, 柯宏慧, 王惠君, 彭健芳, 張訓碩, 謝沛宸, 陳益昇* - - 1 - Phytochemistry - Phytochemistry 2014 103卷(-期):89-98頁
(IF: 3.35, 領域排名: 28, 領域期刊數: 199, 領域排名: 14.07%)

Biological Evaluation of Secondary Metabolites from the Roots of Myrica adenophora
Ya-Chih Ting, Horng-Huey Ko, Hui-Chun Wang, Chien-Fang Peng, Hsun-Shuo Chang, Pei-Chen Hsieh, Ih-Sheng Chen* - - 1 - Phytochemistry - Phytochemistry 2014;103(-):89-98
(IF: 3.35, Journal Ranking: 28, Number of Journals of this Field: 199, Ranking: 14.07%)

47

HPLC-fingerprints and antioxidant constituents of Phyla nodiflora
林芳如, 顏峰霖, 陳佩君, 王木琴, 林忠男, 李江文, 柯宏慧* - - 0 - SCI World Journal - SCI World Journal 2014 2014卷(0期):1-8頁
(IF: 1.73, 領域排名: 13, 領域期刊數: 56, 領域排名: 23.21%)

HPLC-fingerprints and antioxidant constituents of Phyla nodiflora
Fang-Ju Lin, Feng-Lin Yen, Pei-Chun Chen, Moo-Chin Wang, Chun-Nan Lin, Chiang-Wen Lee, Horng-Huey Ko* - - 0 - SCI World Journal - SCI World Journal 2014;2014(0):1-8
(IF: 1.73, Journal Ranking: 13, Number of Journals of this Field: 56, Ranking: 23.21%)

48

Characteristics and properties of a novel in situ method of synthesizing mesoporous TiO2 nanopowders by a simple coprecipitation process without adding surfactant
S.W. Yeh, 柯宏慧, H.M. Chiang, 陳彥伶, J.H. Lee, C.M. Wen, 王木琴* - - 1 - Journal of Alloys and Compounds - J ALLOY COMPD 2014 613卷(15期):107-116頁
(IF: 3.133, 領域排名: 5, 領域期刊數: 74, 領域排名: 6.76%)

Characteristics and properties of a novel in situ method of synthesizing mesoporous TiO2 nanopowders by a simple coprecipitation process without adding surfactant
S.W. Yeh, H.H. Ko, H.M. Chiang, Y.L. Chen, J.H. Lee, C.M. Wen, M.C. Wang* - - 1 - Journal of Alloys and Compounds - J ALLOY COMPD 2014;613(15):107-116
(IF: 3.133, Journal Ranking: 5, Number of Journals of this Field: 74, Ranking: 6.76%)

49

Thermal behavior and crystallization kinetics of cerium dioxide precursor powders
柯宏慧, G. Yang, 王木琴*, X. Zhao - - 1 - CIeramics International - Ceram. Int. 2014 40卷(9期):13953-13959頁
(IF: 2.986, 領域排名: 2, 領域期刊數: 26, 領域排名: 7.69%)

Thermal behavior and crystallization kinetics of cerium dioxide precursor powders
H.H. Ko, G. Yang, M.C. Wang*, X. Zhao - - 1 - CIeramics International - Ceram. Int. 2014;40(9):13953-13959
(IF: 2.986, Journal Ranking: 2, Number of Journals of this Field: 26, Ranking: 7.69%)

50

New and cytotoxic components from Antrodia camphorate
Tzong-Huei Lee, Chien-Chih Chen, Jih-Jung Chen, Hui-Fen Liao, 張訓碩, Ping-Jyun Sung, Mei-Hwei Tseng, Sheng-Yang Wang, 柯宏慧, Yueh-Hsiung Kuo* - - 1 - Molecules - Molecules 2014 19卷(12期):21378-21385頁
(IF: 2.416, 領域排名: 22, 領域期刊數: 58, 領域排名: 37.93%)

New and cytotoxic components from Antrodia camphorate
Tzong-Huei Lee, Chien-Chih Chen, Jih-Jung Chen, Hui-Fen Liao, Hsun-Shuo Chang, Ping-Jyun Sung, Mei-Hwei Tseng, Sheng-Yang Wang, Horng-Huey Ko, Yueh-Hsiung Kuo* - - 1 - Molecules - Molecules 2014;19(12):21378-21385
(IF: 2.416, Journal Ranking: 22, Number of Journals of this Field: 58, Ranking: 37.93%)

51

Isothermal Crystallization Kinetics and Effect of Crystallinity on the Optical Properties of Nanosized CeO2 Powder.
柯宏慧, G. L. Yang, 王木琴*, and X. Zhao - - 0 - Ceramics International - Ceram. Int 2014 40卷(0期):6663-6671頁
(IF: 2.986, 領域排名: 2, 領域期刊數: 26, 領域排名: 7.69%)

Isothermal Crystallization Kinetics and Effect of Crystallinity on the Optical Properties of Nanosized CeO2 Powder.
H. H. Ko, G. L. Yang, M.C. Wang*, and X. Zhao - - 0 - Ceramics International - Ceram. Int 2014;40(0):6663-6671
(IF: 2.986, Journal Ranking: 2, Number of Journals of this Field: 26, Ranking: 7.69%)

52

Effect of Artocarpus communis Extract on UVB Irradiation-Induced Oxidative Stress and Inflammation in Hairless Mice.
Chiang-Wen Lee, 柯宏慧, 蔡志仁, 陳婉姿, 林俊清, 顏峰霖*. - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INT J MOL SCI 2013 14卷(2期):3860-3873頁
(IF: 2.464, 領域排名: 48, 領域期刊數: 152, 領域排名: 31.58%)

Effect of Artocarpus communis Extract on UVB Irradiation-Induced Oxidative Stress and Inflammation in Hairless Mice.
Chiang-Wen Lee ,Horng-Huey Ko , Chee-Yin Chai , Wan-Tzu Chen , Chun-Ching Lin, Feng-Lin Yen*. - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INT J MOL SCI 2013;14(2):3860-3873
(IF: 2.464, Journal Ranking: 48, Number of Journals of this Field: 152, Ranking: 31.58%)

53

Prenylated flavonoids from Artocarpus altilis: Antioxidant activities and inhibitory effects on melanin production.
藍玟君, 曾承煒, 林俊清, 顏峰霖, 柯宏慧*. - - 1 - Phytochemistry - PHYTOCHEMISTRY 2013 89卷(2013期):78-88頁
(IF: 3.35, 領域排名: 28, 領域期刊數: 196, 領域排名: 14.29%)

Prenylated flavonoids from Artocarpus altilis: Antioxidant activities and inhibitory effects on melanin production.
Wen-Chun Lan, Cheng-Wei Tzeng, Chun-Ching Lin, Feng-Lin Yen, Horng-Huey Ko*. - - 1 - Phytochemistry - PHYTOCHEMISTRY 2013;89(2013):78-88
(IF: 3.35, Journal Ranking: 28, Number of Journals of this Field: 196, Ranking: 14.29%)

54

Curcumin Nanoparticles Ameliorate ICAM-1 Expression in TNF-a-Treated Lung Epithelial Cells through p47 phox and MAPKs/AP-1 Pathways.
顏峰霖(1), Ming-Horng Tsai(1), Chuen-Mao Yang, Chan-Jung Liang, 林俊清, Yao-Chang Chiang, Hui-Chun Lee, 柯宏慧, Chiang-Wen Lee* - - 1 - Plos One - PLOS ONE 2013 8卷(5期):e63845頁
(IF: 3.534, 領域排名: 8, 領域期刊數: 55, 領域排名: 14.55%)

Curcumin Nanoparticles Ameliorate ICAM-1 Expression in TNF-a-Treated Lung Epithelial Cells through p47 phox and MAPKs/AP-1 Pathways.
Feng-Lin Yen(1), Ming-Horng Tsai(1), Chuen-Mao Yang, Chan-Jung Liang, Chun-Ching Lin, Yao-Chang Chiang, Hui-Chun Lee, Horng-Huey Ko, Chiang-Wen Lee* - - 1 - Plos One - PLOS ONE 2013;8(5):e63845
(IF: 3.534, Journal Ranking: 8, Number of Journals of this Field: 55, Ranking: 14.55%)

55

Growth behavior of nanosized ceria powders prepared by coprecipitation routes
楊國麗, 柯宏慧, 許育維, 楊國和, 王木琴*, 韓建軍, 趙修健 - - 1 - Ceramics International - CERAM INT 2013 39卷(6期):6805-6811頁
(IF: 2.086, 領域排名: 3, 領域期刊數: 25, 領域排名: 12.00%)

Growth behavior of nanosized ceria powders prepared by coprecipitation routes
G.L. Yang, H. H. Ko, Y. W. Hsu, K. H. Yang, M. C. Wang*, J. J. Han, X. J. Zhao - - 1 - Ceramics International - CERAM INT 2013;39(6):6805-6811
(IF: 2.086, Journal Ranking: 3, Number of Journals of this Field: 25, Ranking: 12.00%)

56

A Novel Monoterpene–Stilbene Adduct with 4,4-Dimethyl-2,3-Diphenylchromane Skeleton from Artocarpus xanthocarpus
柯宏慧*,金語菁,盧梓銘*,陳益昇 - - 1 - CHEMISTRY & BIODIVERSITY - CHEM BIODIVERS 2013 10卷(7期):1269-1275頁
(IF: 1.808, 領域排名: 59, 領域期刊數: 152, 領域排名: 38.82%)

A Novel Monoterpene–Stilbene Adduct with 4,4-Dimethyl-2,3-Diphenylchromane Skeleton from Artocarpus xanthocarpus
H. H. Ko*, Y. J. Jin, T. M. Lu*, and I. S. Chen - - 1 - CHEMISTRY & BIODIVERSITY - CHEM BIODIVERS 2013;10(7):1269-1275
(IF: 1.808, Journal Ranking: 59, Number of Journals of this Field: 152, Ranking: 38.82%)

57

Effect of solute and surfactant addition on the crystallization and morphology of hydroxyapatite powders synthesized by hydrolysis of calcium hydrogen phosphate dehydrate (DCPD)
陳惠亭, H.F. Chang, 柯宏慧, I.M. Hung, 顏峰霖, 黃宏欣, M.H. Hon, 王木琴*, W. J. Shih - - 1 - METALLURGICAL AND MATERIALS TRANSACTIONS A - METALL MATER TRANS A 2013 44卷(2期):1023-1033頁
(IF: 1.73, 領域排名: 10, 領域期刊數: 75, 領域排名: 13.33%)

Effect of solute and surfactant addition on the crystallization and morphology of hydroxyapatite powders synthesized by hydrolysis of calcium hydrogen phosphate dehydrate (DCPD)
H.T. Chen, H.F. Chang, H.H. Ko, I.M. Hung, F.L. Yen, H.H. Huang, M.H. Hon, M. C. Wang*, W. J. Shih - - 1 - METALLURGICAL AND MATERIALS TRANSACTIONS A - METALL MATER TRANS A 2013;44(2):1023-1033
(IF: 1.73, Journal Ranking: 10, Number of Journals of this Field: 75, Ranking: 13.33%)

58

Process parameters on the crystallization and morphology of hydroxyapatite powders prepared by a hydrolysis method
王木琴, M. H. Hon, 陳惠亭*, 顏峰霖, I. M. Hung, 柯宏慧, W. J. Shih - - 1 - METALLURGICAL AND MATERIALS TRANSACTIONS A - METALL MATER TRANS A 2013 44卷(03期):3344-3352頁
(IF: 1.73, 領域排名: 10, 領域期刊數: 75, 領域排名: 13.33%)

Process parameters on the crystallization and morphology of hydroxyapatite powders prepared by a hydrolysis method
M. C. Wang, M. H. Hon, H. T. Chen*, F. L. Yen, I. M. Hung, H. H. Ko, W. J. Shih - - 1 - METALLURGICAL AND MATERIALS TRANSACTIONS A - METALL MATER TRANS A 2013;44(03):3344-3352
(IF: 1.73, Journal Ranking: 10, Number of Journals of this Field: 75, Ranking: 13.33%)

59

Artocarpin attenuates ultraviolet B-induced skin damage in hairless mice by antioxidant and anti-inflammatory effect.
Lee CW, 柯宏慧, 林俊清, 蔡志仁, 陳婉姿, 顏峰霖* - - 1 - FOOD AND CHEMICAL TOXICOLOGY - FOOD CHEM TOXICOL 2013 60卷(-期):123-129頁
(IF: 3.01, 領域排名: 12, 領域期刊數: 124, 領域排名: 9.68%)

Artocarpin attenuates ultraviolet B-induced skin damage in hairless mice by antioxidant and anti-inflammatory effect.
Lee CW, Ko HH, Lin CC, Chai CY, Chen WT, Yen FL - - 1 - FOOD AND CHEMICAL TOXICOLOGY - FOOD CHEM TOXICOL 2013;60(-):123-129
(IF: 3.01, Journal Ranking: 12, Number of Journals of this Field: 124, Ranking: 9.68%)

60

Norartocarpetin from a folk medicine Artocarpus communis plays a melanogenesis inhibitor without cytotoxicity and skin irritation in mice.
柯宏慧, Yi-Ting Tsai, 顏銘宏, 林俊清, Chan-Jung Liang, Tsung-Han Yang, Chiang-Wen Lee*, 顏峰霖* - - 1 - BMC Complementary and Alternative Medicine - 2013 13卷(0期):348頁
(IF: 1.877, 領域排名: 8, 領域期刊數: 22, 領域排名: 36.36%)

Norartocarpetin from a folk medicine Artocarpus communis plays a melanogenesis inhibitor without cytotoxicity and skin irritation in mice.
Horng-Huey Ko(1), Yi-Ting Tsai(1), Ming-Hong Yen, Chun-Ching Lin, Chan-Jung Liang, Tsung-Han Yang, Chiang-Wen Lee* and Feng-Lin Yen* - - 1 - BMC Complementary and Alternative Medicine - 2013;13(0):348
(IF: 1.877, Journal Ranking: 8, Number of Journals of this Field: 22, Ranking: 36.36%)

61

9 mol %氧化鋅包覆二氧化鈦納米晶粉體應用於防曬化妝品中
柯宏慧,陳惠亭,顏峰霖,盧宛辰,郭致瑋,王木琴* - - 1 - International Journal of Molecular Sciences - INT J MOL SCI 2012 13卷(0期):1658-1669頁
(IF: 2.279, 領域排名: 40, 領域期刊數: 144, 領域排名: 27.78%)

Preparation of TiO2 Nanocrystallite Powders Coated with 9 mol% ZnO for Cosmetic Applications in Sunscreens
Horng-Huey Ko, Hui-Ting Chen, Feng-Ling Yen, Wan-Chen Lu, Chih-Wei Kuo, Moo-Chin Wang * - - 1 - International Journal of Molecular Sciences - INT J MOL SCI 2012;13(0):1658-1669
(IF: 2.279, Journal Ranking: 40, Number of Journals of this Field: 144, Ranking: 27.78%)

62

Resveratrol nanoparticle system improves dissolution properties and enhances the hepatoprotective effect of resveratrol through antioxidant and anti-inflammatory pathway.
Chiang-Wen Lee, 顏峰霖,黃浩偉,吳姿慧,柯宏慧,曾文盛*,林俊清* - - 1 - Journal of Agricultural and Food Chemistry - J AGR FOOD CHEM 2012 60卷(18期):4662-4671頁
(IF: 2.816, 領域排名: 2, 領域期刊數: 55, 領域排名: 3.64%)

Resveratrol nanoparticle system improves dissolution properties and enhances the hepatoprotective effect of resveratrol through antioxidant and anti-inflammatory pathway.
Chiang-Wen Lee, Feng-Lin Yen, Haw-Wei Huang, Tzu-Hui Wu, Horng-Huey Ko, Wen-Sheng Tzeng*, Chun-Ching Lin* - - 1 - Journal of Agricultural and Food Chemistry - J AGR FOOD CHEM 2012;60(18):4662-4671
(IF: 2.816, Journal Ranking: 2, Number of Journals of this Field: 55, Ranking: 3.64%)

63

Glucosides of Dihydrochalcones and Benzenoid, and Antioxidant Activity from the Root of Anneslea lanceolata
黃弘宜,柯宏慧,Yu-Jin Jin, Sheng-Zehn Yang, You-An Shih, 陳益昇* - - 1 - Phytochemistry - Phytochemistry 2012 78卷(1期):120-125頁
(IF: 3.15, 領域排名: 24, 領域期刊數: 185, 領域排名: 12.97%)

Glucosides of Dihydrochalcones and Benzenoid, and Antioxidant Activity from the Root of Anneslea lanceolata
Hung-Yi Huang, Horng-Huey Ko, Yu-Jin Jin, Sheng-Zehn Yang, You-An Shih, Ih-Sheng Chen* - - 1 - Phytochemistry - Phytochemistry 2012;78(1):120-125
(IF: 3.15, Journal Ranking: 24, Number of Journals of this Field: 185, Ranking: 12.97%)

64

Understanding the Biocompatibility of Sintered Calcium Phosphate with Ratio of [Ca]/[P] = 1.50
顏峰霖,施威任,洪敏雄,陳惠亭,洪逸明,柯宏慧,王木琴* - - 1 - Journal of Nanomaterials - J NANOMATER 2012 2012卷(0期):doi:10.1155/2012/325605(ASAP)頁
(IF: 1.675, 領域排名: 78, 領域期刊數: 222, 領域排名: 35.14%)

Understanding the Biocompatibility of Sintered Calcium Phosphate with Ratio of [Ca]/[P] = 1.50
Feng-Lin Yen, Wei-Jen Shih, Min-Hsiung Hon, Hui-Ting Chen, I-Ming Hung, Homg-Huey Ko, and Moo-Chin Wang* - - 1 - Journal of Nanomaterials - J NANOMATER 2012;2012(0):doi:10.1155/2012/325605(ASAP)
(IF: 1.675, Journal Ranking: 78, Number of Journals of this Field: 222, Ranking: 35.14%)

65

Effect of solute and surfactant addition on the crystallization and morphology of hydroxyapatite powders synthesized by hydrolysis of calcium hydrogen phosphate dehydrate (DCPD)
陳惠亭, 張馨方, 柯宏慧, 洪逸明,顏峰霖, 黃宏欣, 洪敏雄, 王木琴*, 施威任 - - 1 - Metallurgical and Materials Transaction A - METALL MATER TRANS A 2012 44卷(A期):1023-1033頁
(IF: 1.712, 領域排名: 7, 領域期刊數: 74, 領域排名: 9.46%)

Effect of solute and surfactant addition on the crystallization and morphology of hydroxyapatite powders synthesized by hydrolysis of calcium hydrogen phosphate dehydrate (DCPD)
H. T. Chen, H. F. Chang, H. H. Ko, I. M. Hung, F. L Yen, H. H. Huang, M. H. Hon, M. C. Wang*, W. J. Shih - - 1 - Metallurgical and Materials Transaction A - METALL MATER TRANS A 2012;44(A):1023-1033
(IF: 1.712, Journal Ranking: 7, Number of Journals of this Field: 74, Ranking: 9.46%)

66

石莧萃取物之美白活性機轉
顏峰霖,王木琴,梁展榮,柯宏慧,李江文 - - 1 - Evidence-Based Complementary and Alternative Medicine. - EVID-BASED COMPL ALT 2012 2012卷(867494期):9頁
(IF: 2.964, 領域排名: 3, 領域期刊數: 19, 領域排名: 15.79%)

Melanogenesis Inhibitor(s) from Phyla nodiflora Extract.
Yen FL, Wang MC, Liang CJ, Ko HH*, Lee CW*. - - 1 - Evidence-Based Complementary and Alternative Medicine. - EVID-BASED COMPL ALT 2012;2012(867494):9
(IF: 2.964, Journal Ranking: 3, Number of Journals of this Field: 19, Ranking: 15.79%)

67

Synthesis and structure-activity relationship study of deoxybenzoins on relaxing effects of porcine coronary artery
盧梓銘*,郭玳璜,柯宏慧,黃良得 - - 1 - J. Agric. Food Chem. - J AGR FOOD CHEM 2010 58卷(18期):10027-10032頁
(IF: 2.816, 領域排名: 2, 領域期刊數: 55, 領域排名: 3.64%)

Synthesis and structure-activity relationship study of deoxybenzoins on relaxing effects of porcine coronary artery
T. M. Lu,* D. H. Kuo, H. H. Ko, and L. T. Ng - - 1 - J. Agric. Food Chem. - J AGR FOOD CHEM 2010;58(18):10027-10032
(IF: 2.816, Journal Ranking: 2, Number of Journals of this Field: 55, Ranking: 3.64%)

68

從台灣穗花杉分離得到具有抑制黃嘌呤氧化酶的三帖;類,在正常人類尿道上皮細胞與 膀胱癌細胞中能藉由減少活性氧來保護cispplatin誘發之細胞死亡
林忠男,黃阿梅,林凱偉,侯自銓,柯宏慧*,楊世群,蒲永孝 - - 1 - Phytochemistry - PHYTOCHEMISTRY 2010 71卷(0期):2140-2146頁
(IF: 3.15, 領域排名: 24, 領域期刊數: 185, 領域排名: 12.97%)

Xanthine oxidase inhibitory terpenoids of Amentotaxus formosana protect cisplatin-induced cell death by reducing reactive oxygen species (ROS) in normal human urothelial and bladder cancer cells
C-N Lin, A-M Huang, K-W Lin, T-C Hour, H-H Ko*, S-C Yang, Y-S Pu - - 1 - Phytochemistry - PHYTOCHEMISTRY 2010;71(0):2140-2146
(IF: 3.15, Journal Ranking: 24, Number of Journals of this Field: 185, Ranking: 12.97%)

69

麵包樹及馬來橡膠之抗氧化黃酮類
林凱偉,劉瓊惠,涂煌堯,柯宏慧,魏百祿* - - 1 - Food Chemistry - FOOD CHEM 2009 115卷(2期):558-562頁
(IF: 2.696, 領域排名: 9, 領域期刊數: 107, 領域排名: 8.41%)

Antioxidant prenylflavonoids from Artocarpus communis and Artocarpus elasticus
K. W. Lin, C. H. Liu, H. Y. Tu , H. H. Ko , B. L. Wei* - - 1 - Food Chemistry - FOOD CHEM 2009;115(2):558-562
(IF: 2.696, Journal Ranking: 9, Number of Journals of this Field: 107, Ranking: 8.41%)

70

Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins
黃良得,柯宏慧,盧梓銘* - - 1 - Bioorg. Med. Chem. - BIOORGAN MED CHEM 2009 17卷(13期):4360-4366頁
(IF: 3.075, 領域排名: 10, 領域期刊數: 40, 領域排名: 25.00%)

Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins
L. T. Ng, H. H. Ko, T. M. Lu* - - 1 - Bioorg. Med. Chem. - BIOORGAN MED CHEM 2009;17(13):4360-4366
(IF: 3.075, Journal Ranking: 10, Number of Journals of this Field: 40, Ranking: 25.00%)

71

DNA strand-scission by phloroglucinols and lignans from heartwood of Garcinia subelliptica Merr. and Justicia plants
呂亦晃, 魏百祿, 柯宏慧, 林忠男* - - 1 - Phytochemistry - PHYTOCHEMISTRY 2008 69卷(08期):225-233頁
(IF: 2.946, 領域排名: 21, 領域期刊數: 155, 領域排名: 13.55%)

DNA strand-scission by phloroglucinols and lignans from heartwood of Garcinia subelliptica Merr. and Justicia plants
Yi-Huang Lu, Bai-Luh Wei, Horng-Huey Ko, Chun-Nan Lin* - - 1 - Phytochemistry - PHYTOCHEMISTRY 2008;69(08):225-233
(IF: 2.946, Journal Ranking: 21, Number of Journals of this Field: 155, Ranking: 13.55%)

72

Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae
柯宏慧, 洪啟峰, 王繼平, 林忠男* - - 1 - PHYTOCHEMISTRY - PHYTOCHEMISTRY 2008 69卷(07期):234-239頁
(IF: 2.946, 領域排名: 21, 領域期刊數: 155, 領域排名: 13.55%)

Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae
Horng-Huey Ko, Chi-Feng Hung, Jih-Pyang Wang, Chun-Nan Lin* - - 1 - PHYTOCHEMISTRY - PHYTOCHEMISTRY 2008;69(07):234-239
(IF: 2.946, Journal Ranking: 21, Number of Journals of this Field: 155, Ranking: 13.55%)

73

Anti-tyrosinase and Antioxidant Effects of ent-Kaurane Diterpenes from Leaves of Broussonetia papyrifera
柯宏慧*, 張雯琳, 盧梓銘* - - 1 - Journal of Natural Products - J NAT PROD 2008 71卷(11期):1930-1933頁
(IF: 2.843, 領域排名: 4, 領域期刊數: 60, 領域排名: 6.67%)

Anti-tyrosinase and Antioxidant Effects of ent-Kaurane Diterpenes from Leaves of Broussonetia papyrifera
Horng- Huey Ko,* Wen-Ling Chang, and Tzy-Ming Lu* - - 1 - Journal of Natural Products - J NAT PROD 2008;71(11):1930-1933
(IF: 2.843, Journal Ranking: 4, Number of Journals of this Field: 60, Ranking: 6.67%)

74

Inhibition of lipopolysaccharide-stimulated NO production by crotafuran B in RAW 264.7 macrophages involves the blockade of NF-kappa B activation through the increase in I kappa B alpha synthesis
Lin MW, 曹羅悌, 黃麗嬌, Kuo SC, 翁靖如, 柯宏慧, 林忠男, 李妙蓉, 王繼平* - - 1 - TOXICOLOGY AND APPLIED PHARMACOLOGY - TOXICOL APPL PHARM 2006 210卷(1-2期):108-115頁
(IF: 4.722, 領域排名: 4, 領域期刊數: 76, 領域排名: 5.26%)

Inhibition of lipopolysaccharide-stimulated NO production by crotafuran B in RAW 264.7 macrophages involves the blockade of NF-kappa B activation through the increase in I kappa B alpha synthesis
Lin MW, Tsao LT, Huang LJ, Kuo SC, Weng JR, Ko HH, Lin CN, Lee MR, Wang JP - - 1 - TOXICOLOGY AND APPLIED PHARMACOLOGY - TOXICOL APPL PHARM 2006;210(1-2):108-115
(IF: 4.722, Journal Ranking: 4, Number of Journals of this Field: 76, Ranking: 5.26%)

75

Antiplatelet prenylflavonoids from Artocarpus communis.
翁靖如, 詹聖慶, 呂亦晃, 林獻誠, 柯宏慧, 林忠男* - - 1 - PHYTOCHEMISTRY - PHYTOCHEMISTRY 2006 67卷(8期):824-829頁
(IF: 2.417, 領域排名: 24, 領域期刊數: 147, 領域排名: 16.33%)

Antiplatelet prenylflavonoids from Artocarpus communis.
Weng JR, Chan SC, Lu YH, Lin HC, Ko HH, Lin CN* - - 1 - PHYTOCHEMISTRY - PHYTOCHEMISTRY 2006;67(8):824-829
(IF: 2.417, Journal Ranking: 24, Number of Journals of this Field: 147, Ranking: 16.33%)

76

Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents
翁舷誌, Liu CT, 曹羅悌, 翁靖如, 柯宏慧, 王繼平, 林忠男* - - 1 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - EUR J MED CHEM 2005 40卷(1期):103-112頁
(IF: 2.022, 領域排名: 14, 領域期刊數: 34, 領域排名: 41.18%)

Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents
Won SJ, Liu CT, Tsao LT, Weng JR, Ko HH, Wang JP, Lin CN* - - 1 - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - EUR J MED CHEM 2005;40(1):103-112
(IF: 2.022, Journal Ranking: 14, Number of Journals of this Field: 34, Ranking: 41.18%)

77

Cytotoxic Prenylflavonoids from Artocarpus elasticus
柯宏慧, 呂亦晃, 楊勝任, 翁舷誌, 林忠男* - - 1 - JOURNAL OF NATURAL PRODUCTS - J NAT PROD 2005 68卷(11期):1692-1695頁
(IF: 2.267, 領域排名: 8, 領域期刊數: 59, 領域排名: 13.56%)

Cytotoxic Prenylflavonoids from Artocarpus elasticus
Ko HH, Lu YH, Yang SZ, Won SJ, Lin CN* - - 1 - JOURNAL OF NATURAL PRODUCTS - J NAT PROD 2005;68(11):1692-1695
(IF: 2.267, Journal Ranking: 8, Number of Journals of this Field: 59, Ranking: 13.56%)

78

肉毒桿菌在美容的應用
柯宏慧* - - 0 - 生物產業 (Bioindustry) - 2005 16卷(3期):3-9頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

無
無 - - 0 - 生物產業 (Bioindustry) - 2005;16(3):3-9
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

79

自爵床分離得到之二種新的Arylnaphthalide Ligans 及其抗血小板凝集成分
翁靖如, 柯宏慧, 葉亭利, 林獻誠, 林忠男* - - 1 - ARCHIV DER PHARMAZIE - ARCH PHARM 2004 337卷(4期):207-212頁
(IF: 0.653, 領域排名: 74, 領域期刊數: 123, 領域排名: 60.16%)

Two New Arylnaphthalide Lignans and Antiplatelet Constituents from Justicia procumbens
Jing-Ru Weng, Horng-Huey Ko, Ting-Li Yeh, Hsien-Cheng Lin and Chun-Nan Lin,* - - 1 - ARCHIV DER PHARMAZIE - ARCH PHARM 2004;337(4):207-212
(IF: 0.653, Journal Ranking: 74, Number of Journals of this Field: 123, Ranking: 60.16%)

80

Chalcone衍生物結構與抗血小板凝集活性之關係
柯宏慧,薛興國,劉政宗,林獻誠,鄧哲明,林忠男* - - 1 - Journal of Pharmacy and Pharmacology - J PHARM PHARMACOL 2004 56卷(10期):1333-1337頁
(IF: 1.348, 領域排名: 117, 領域期刊數: 186, 領域排名: 62.90%)

Structure-activity relationship studies on chalcone derivatives: potent inhibition of platelet aggregation
Horng-Huey Ko, Hsin-Kaw Hsieh, Cheng-Tsung Liu, Hsien-Chen Lin, Che-Ming Teng and Chun-Nan Lin* - - 1 - Journal of Pharmacy and Pharmacology - J PHARM PHARMACOL 2004;56(10):1333-1337
(IF: 1.348, Journal Ranking: 117, Number of Journals of this Field: 186, Ranking: 62.90%)

81

Stimulation of cellular free Ca2+ elevation and inhibition of store-operated Ca2+ entry by kazinol B in neutrophils
王繼平,許美鳳,柯宏慧,林忠男* - - 1 - Naunyn-Schmiedeberg's Archives of Pharmacology - N-S ARCH PHARMACOL 2004 370卷(6期):500-509頁
(IF: 1.963, 領域排名: 83, 領域期刊數: 186, 領域排名: 44.62%)

Stimulation of cellular free Ca2+ elevation and inhibition of store-operated Ca2+ entry by kazinol B in neutrophils
Jih-Pyang Wang, Mei-Feng Hsu, Horng-Huey Ko and Chun-Nan Lin - - 1 - Naunyn-Schmiedeberg's Archives of Pharmacology - N-S ARCH PHARMACOL 2004;370(6):500-509
(IF: 1.963, Journal Ranking: 83, Number of Journals of this Field: 186, Ranking: 44.62%)

82

自Crotalaria pallida 及C. assamica分離得到的抗發炎黃酮類化合物
柯宏慧,翁靖如,曹羅悌,顏銘宏,王繼平,林忠男* - - 1 - Bioorganic & Medicinal Chemistry Letters  - BIOORGAN MED CHEM 2004 14卷(0期):1011-1014頁
(IF: 2.018, 領域排名: 12, 領域期刊數: 36, 領域排名: 33.33%)

Anti-inflammatory Flavonoids and Pterocarpanoid from Crotalaria pallida and C. assamica
H. H. Ko, J.R. Weng, L.T. Tsao, M.H. Yen, J.P. Wang, and C.N. Lin* - - 1 - Bioorganic & Medicinal Chemistry Letters  - BIOORGAN MED CHEM 2004;14(0):1011-1014
(IF: 2.018, Journal Ranking: 12, Number of Journals of this Field: 36, Ranking: 33.33%)

83

爵床之抗癌木質酚及對小白鼠巨噬細胞之抗NO及TNF-α作用
戴秀華, 林宜辰, 蔡玫琳, 曹羅悌, 柯宏慧, 鍾美英, 呂政昌, 王繼平, 翁舷誌, 林忠男 - - 1 - Journal of Natural Products - 2002 65卷(3期):379-381頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Potent Cytotoxic Lignans from Justicia procumbens and Their Effects on Nitric Oxide and Tumor Necrosis Factor-α Production in Mouse Macrophages
Shiow-Hwa Day, Yi-Chen Lin, Mei-Lin Tsai, Lo-Ti Tsao, Horng-Huey Ko, Mei-Ing Chung, Jeng-Chang Lee, Jih-Pyang Wang, Shen-Jeu Won, Chun-nan Lin - - 1 - Journal of Natural Products - 2002;65(3):379-381
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

84

Two Novel and Anti-Inflammatory Constituents of Artocarpus rigida
呂亦晃, 林忠男, 柯宏慧, 楊勝任, 曹羅悌, 王繼平 - - 1 - HCA - 2002 85卷(6期):1626-1632頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Two Novel and Anti-Inflammatory Constituents of Artocarpus rigida
Yi-Huang Lu, Chun-Nan Lin, Horng-Huey Ko, Sheng-Zehn Yang, Lo-Ti Tsao, Jih-Pyang Wang - - 1 - HCA - 2002;85(6):1626-1632
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

85

扮演抗血小板凝劑及鈣離子阻斷劑的Chalcones化合物
林忠男, 薛興國, 柯宏慧, �,美鳳, 林獻成, 張雅玲, 鍾美英, 康照洲, 王繼平, 鄧哲明 - - 1 - Drug Development Research - 2001 53卷(0期):9-14頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Chalcones as potent antiplatelet agents and calcium channel blockers
Chun-Nan Lin, Hsin-Kaw Hsieh, Horng-Huey Ko, Mei-Feng Hsu, Hsien-Cheng Lin, Ya-Ling Chang, Mei-Ing Chung, Jaw-Jou Kang, Jih-Pyang Wang, Che-Ming Teng - - 1 - Drug Development Research - 2001;53(0):9-14
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

86

從猴面果植物中,分離得到一個新的酚類化合物--Artocarpol F
柯宏慧, 楊勝任, 林忠男 - - 1 - Tetrahedron letters - 2001 42卷(0期):5269-5270頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Artocarpol F, a phenolic compound with a novel skeleton, isolated from Artocarpus rigida
Horng-Huey Ko, Sheng-Zehn Yang, Chun-Nan-Lin - - 1 - Tetrahedron letters - 2001;42(0):5269-5270
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

87

單氧化黃酮類及丙醇胺黃酮類之合成,抗血小板凝集及血管鬆弛作用
鍾美英, 韓鳳文, 林獻誠, 劉崇喜, 黃保林, 柯宏慧, 張雅玲, 康照洲, 鄧哲明, 林忠男 - - 1 - Pharmacy and Pharmacology - 2001 53卷(0期):1601-1609頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Synthesis, antiplatelet and vasorelaxing effects of monooxygenated flavones and flavonoxypropanolamines
Mei-Ing Chung, Feng-Wen Han, Hsien-Cheng Lin, Shorong-Shii Liou, Pao-Ling Huang, Horng-Huey Ko,Ya-Ling Chang, Jaw-Jou Kang, Che-Ming Teng, Chun-Nan Lin - - 1 - Pharmacy and Pharmacology - 2001;53(0):1601-1609
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

88

由猴面果分離之抗發炎成分.
鍾美英, 柯宏慧, 顏銘宏, 林忠男, 楊勝任, 曹羅悌, 王繼平. - - 1 - Helvetica Chimica Acta - 2000 83卷(0期):1200-1204頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Artocarpol A, a novel constituent with potent anti-inflammatory effect, isolated from Artocarpus rigida.
Mei-Ing Chung, Horng-Kuey Ko, Ming-Hong Yen, Chun-Nan Lin, Sheng-Zehn Yang, Lo-Ti Tsao, and Jih-Pyang Wang. - - 1 - Helvetica Chimica Acta - 2000;83(0):1200-1204
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

89

猴面果分離之新成分.
柯宏慧, 林忠男 及 楊勝任. - - 1 - Helvetica Chemica Acta - 2000 83卷(11期):3000-3005頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

New constituents of Artocarpus rigida.
Horng-Huey Ko, Chun-Nan Lin, Sheng-Zehn Yang. - - 1 - Helvetica Chemica Acta - 2000;83(11):3000-3005
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

90

小構樹細胞毒成分
柯宏慧,嚴銘宏,吳如蓉,翁舷誌,林忠男 - - 1 - Journal of Natural Products - 1999 62卷(1期):164-166頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Cytotoxic isoprenylated flavans of Broussonetia kazinoki
Horng-Huey Ko, Ming-hong Yen, Ru-Rong Wu, Shen-Jeu Won, and Chun-Nan Lin. - - 1 - Journal of Natural Products - 1999;62(1):164-166
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

91

小葉桑之化學與活性成分.
柯宏慧,王志鉦,林獻誠,王繼平,林忠男 - - 1 - Biochimica et Biophysica Acta - 1999 1428卷(0期):293-299頁
(IF: , 領域排名: , 領域期刊數: , 領域排名: %)

Chemistry and biological activies of constituents from Morus australis.
Horng-Huey Ko, Jeh-Jeng Wang, Hsien-Cheng Lin, Jih-Pyang Wang, and Chun-Nan Lin. - - 1 - Biochimica et Biophysica Acta - 1999;1428(0):293-299
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

92

Bioactive constituents of Morus australis and Broussonetia papyrifera.
柯宏慧, 余淑美, 柯逢年,鄧哲明, 及 林忠男. - - 1 - J. Nat. Prod. - 1997 60卷(0期):1008-1011頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

待補
待補 - - 1 - J. Nat. Prod. - 1997;60(0):1008-1011
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
117 — N 國科會(原科技部) — NSTC115-2320-B-037-016-MY3 — 1 個人型
電腦輔助設計天然物奈米載體以緩解污染顆粒誘導之皮膚損傷(3/3)( )
2028/08/01 ~ 2029/07/31
2
116 — N 國科會(原科技部) — NSTC115-2320-B-037-016-MY3 — 1 個人型
電腦輔助設計天然物奈米載體以緩解污染顆粒誘導之皮膚損傷(2/3)( )
2027/08/01 ~ 2029/07/31
3
115 — N 國科會(原科技部) — NSTC115-2320-B-037-016-MY3 — 1 個人型
電腦輔助設計天然物奈米載體以緩解污染顆粒誘導之皮膚損傷(1/3)( )
2026/08/01 ~ 2029/07/31
4
115 — Z 大專學生研究計畫及博士後 — NSTC115-2811-B-037-033 — 9 博士後研究員
博士級研究人員--鍾慧于( )
2026/10/01 ~ 2027/04/30
5
114 — N 國科會(原科技部) — NSTC112-2320-B-037-022-MY3 — 1 個人型
結合天然物綠色萃取技術與奈米製劑開發可減緩空氣懸浮微粒傷害之新型皮膚保護劑(3/3)( )
2025/08/01 ~ 2026/10/31
6
113 — N 國科會(原科技部) — NSTC112-2320-B-037-022-MY3 — 1 個人型
結合天然物綠色萃取技術與奈米製劑開發可減緩空氣懸浮微粒傷害之新型皮膚保護劑(2/3)( )
2024/08/01 ~ 2026/10/31
7
113 — Z 大專學生研究計畫及博士後 — NSTC114-2813-C-037-021-B — 8 大專學生研究計畫
114年度大專學生研究計畫-岳怡萱(香��2)( )
2025/07/01 ~ 2026/02/28
8
112 — KC 高醫陽明交大 — NYCUKMU-112-I004 — 2 整合型
開發治療心臟衰竭之複合藥物及其靶向樹狀分子載體( )
2023/01/01 ~ 2023/12/31
9
112 — N 國科會(原科技部) — NSTC112-2320-B-037-022-MY3 — 1 個人型
結合天然物綠色萃取技術與奈米製劑開發可減緩空氣懸浮微粒傷害之新型皮膚保護劑(1/3)( )
2023/08/01 ~ 2026/10/31
10
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-052-B — 8 大專學生研究計畫
113年度大專學生研究計畫-莊心妤(藥學2)( )
2024/07/01 ~ 2025/02/28
11
111 — KK 高科大高醫產學合作補助 —   —  
利用綠色萃取法開發台產植物保護劑減緩空污細懸浮微粒所引起之皮膚損傷( )
2022/11/01 ~ 2023/10/31
12
111 — M 高醫(種子計畫) — KMU-M112002 —  
高雄地區不同來源之空污細懸浮微粒(PM2.5)對皮膚損傷之探討及天然物皮膚屏障保護劑之開發( )
2023/01/01 ~ 2023/12/31
13
110 — M 高醫(種子計畫) — KMU-M111004 —  
利用無溶劑微波萃取法協助開發皮膚化學保護劑(II)( )
2022/01/01 ~ 2022/12/31
14
110 — Z 大專學生研究計畫及博士後 — MOST111-2813-C-037-052-B — 8 大專學生研究計畫
111年度大專學生研究計畫-田叡融(香��3)( )
2022/07/01 ~ 2023/02/28
15
109 — N 國科會(原科技部) — MOST109-2320-B-037-016 — 1 個人型
利用綠色無溶劑微波萃取法協助開發皮膚化學保護劑( )
2020/08/01 ~ 2021/10/31
16
109 — Z 大專學生研究計畫及博士後 — MOST110-2813-C-037-149-B — 8 大專學生研究計畫
110年度大專學生研究計畫-黃怡雯(香��2)( )
2021/07/01 ~ 2022/02/28
17
109 — Z 大專學生研究計畫及博士後 — MOST110-2813-C-037-150-B — 8 大專學生研究計畫
110年度大專學生研究計畫-楊琇淇(香��2)( )
2021/07/01 ~ 2022/02/28
18
108 — N 國科會(原科技部) — MOST108-2320-B-037-023 — 1 個人型
利用無溶劑綠色萃取技術提高活性天然物萃取率及其應用價值( )
2019/08/01 ~ 2020/10/31
19
108 — TC 研究中心計畫 — KMU-TC108A03-9 — 6 研究中心
使用益生菌及植物共生菌開發多元皮膚保護活性成分—提高化�菻~產業應用價值及經濟效益之New Solution( )
2019/08/01 ~ 2020/07/31
20
107 — N 國科會(原科技部) — MOST107-2632-B-037-001 — 2 整合型
運用智慧電子感官分析系統協助開發具神經保護作用之台產植物芳香組成配方(3/3)( )
2018/08/01 ~ 2019/10/31
21
106 — N 國科會(原科技部) — MOST105-2320-B-037-009-MY2 — 1 個人型
建置光化學保護篩選平台並自天然物中開發具有降低紫外線傷害之光化學保護劑(2/2)( )
2017/08/01 ~ 2018/10/31
22
106 — N 國科會(原科技部) — MOST106-2632-B-037-002 — 2 整合型
運用智慧電子感官分析系統協助開發具神經保護作用之台產植物芳香組成配方(2/3)( )
2017/08/01 ~ 2018/10/31
23
106 — Z 大專學生研究計畫及博士後 — MOST107-2813-C-037-048-B — 8 大專學生研究計畫
107年度大專學生研究計畫-劉姿瑩(香��3)( )
2018/07/01 ~ 2019/02/28
24
105 — N 國科會(原科技部) — MOST105-2632-B-037-003 — 2 整合型
運用智慧電子感官分析系統協助開發具神經保護作用之台產植物芳香組成配方(1/3)( )
2016/08/01 ~ 2017/10/31
25
105 — N 國科會(原科技部) — MOST105-2320-B-037-009-MY2 — 1 個人型
建置光化學保護篩選平台並自天然物中開發具有降低紫外線傷害之光化學保護劑(1/2)( )
2016/08/01 ~ 2018/10/31
26
105 — TP 頂尖計畫(高醫) — KMU-TP105H01 —  
子計畫一、利用台灣產植物之二次代謝產物開發具有抗癌、抗登革熱及改善睡眠品質之先導藥物( )
2016/11/01 ~ 2017/10/31
27
104 — N 國科會(原科技部) — MOST104-2320-B-037-008 — 1 個人型
延緩皮膚老化之天然來源光化學保護劑開發( )
2015/08/01 ~ 2016/07/31
28
104 — TP 頂尖計畫(高醫) — KMU-TP104H01 —  
子計畫一、利用台灣產植物之二次代謝產物開發具有抗癌、抗登革熱及改善睡眠品質之先導藥物( )
2015/10/01 ~ 2016/09/30
29
103 — N 國科會(原科技部) — NSC102-2320-B-037-004-MY2 — 1 個人型
自植物萃取物中開發美白或光化學保護劑,以作為化�菻~活性添加物之用(2/2)( )
2014/08/01 ~ 2015/07/31
30
103 — TP 頂尖計畫(高醫) — KMU-TP103H03 —  
利用台灣產植物之二次代謝產物開發葡萄糖醛酸酶抑制劑( )
2014/08/01 ~ 2015/07/31
31
102 — N 國科會(原科技部) — NSC102-2320-B-037-004-MY2 — 1 個人型
自植物萃取物中開發美白或光化學保護劑,以作為化�菻~活性添加物之用(1/2)( )
2013/08/01 ~ 2015/07/31
32
101 — N 國科會(原科技部) — NSC101-2320-B-037-029 — 1 個人型
鴨舌廣及蘭嶼麵包樹活性成分於皮膚美白及抗發炎機轉探討( )
2012/08/01 ~ 2013/07/31
33
100 — N 國科會(原科技部) — NSC99-2320-B-037-021-MY2 — 1 個人型
鴨舌廣及蘭嶼麵包樹之化�菻O養品潛力開發及其指紋圖譜建立(2/2)( )
2011/08/01 ~ 2012/07/31
34
099 — N 國科會(原科技部) — NSC99-2320-B-037-021-MY2 — 1 個人型
鴨舌廣及蘭嶼麵包樹之化�菻O養品潛力開發及其指紋圖譜建立(1/2)( )
2010/08/01 ~ 2012/07/31
35
098 — N 國科會(原科技部) — NSC98-2320-B-037-012 — 1 個人型
自鴨舌黃及林投中開發化�菻~活性添加物( )
2009/08/01 ~ 2010/07/31
36
097 — M 高醫(種子計畫) — KMU-M098010 —  
石莧地上部抗發炎、抗落胺酸酶及抗氧化活性成分研究( )
2009/01/01 ~ 2009/12/31
37
096 — N 國科會(原科技部) — NSC96-2320-B-037-021 — 1 個人型
構樹及過江藤於抗發炎、抗酪胺酸�﹞峓飫韙し滶鴗尬蝭銃}發與研究( )
2007/08/01 ~ 2008/07/31
38
095 — N 國科會(原科技部) — NSC95-2320-B-037-020- — 1 個人型
常見桑科植物(麵包樹及構樹)及其相關衍生物(二氫查酮)對美白及抗發炎之潛能及其開發研究( )
2006/08/01 ~ 2007/07/31
39
094 — N 國科會(原科技部) — NSC94-2320-B-037-037- — 1 個人型
台產野百合屬植物黃豬屎豆及太陽麻之抗發炎活性成分研究( )
2005/08/01 ~ 2006/07/31
40
093 — N 國科會(原科技部) — NSC93-2320-B-037-052- — 1 個人型
台產野百合屬植物黃豬屎豆及太陽麻之抗發炎活性成分研究( )
2004/08/01 ~ 2005/07/31
41
092 — N 國科會(原科技部) — NSC 92-2320-B-037-066- — 1 個人型
響鈴豆之抗發炎活性成分研究( )
2003/08/01 ~ 2004/07/31

 Patent

NO Patent Name Country Certified Date Patent No
1 石莧萃取物用於皮膚美白 中華民國 2016/02/21 I522127
2 麵包樹萃取物做為防曬保養品添加物來預防紫外線傷害皮膚之用途 中華民國 2015/08/21 I496593
3 麵包樹萃取物預防紫外線傷害皮膚的用途 中國 2017/04/12 2447356
4 含矽氧化鋯坯體之製造方法 中華民國 2016/05/01 I531552
5 含矽氧化鋯燒結體的製法 中國 2018/08/14 3031690
6 含矽氧化鋯鍛燒體及燒結體之製法 美國 2016/12/20 9,522,848
7 黃烷類化合物小構樹醇M、小構樹醇N及7,4’-二羥基-3’-甲氧基黃烷之用途及包含小構樹醇M、7,4’-二羥基-3’-甲氧基黃烷之美白組合物 中華民國 2016/08/21 I546083
8 ?烷?化合物用途及包含小构?醇M、7,4’-二?基-3’-甲氧基?烷的美白?合物 中國 2019/11/22 3607165
9 指甲油筆 中國 2017/08/01 6350134
10 指甲油筆 中華民國 2017/10/21 I602527
11 指甲油筆 中華民國 2017/04/11 M539270
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