MENU

 Education

School ¡X Major ¡X Degree Duration

°ê¥ß¶§©ú¤j¾Ç ¡X ·L¥Íª«§K¬Ì¬ã¨s©Ò(²¦) ¡X ³Õ¤h

Doctorate, Graduate Institute of Microbiology and Immunology, National Yang Ming University

1989/09 ¡X 1996/06

°ê¥ß¶§©ú¤j¾Ç ¡X ·L¥Íª«§K¬Ì¬ã¨s©Ò(²¦) ¡X ºÓ¤h

Master, Graduate Institute of Microbiology and Immunology, National Yang Ming University

1987/09 ¡X 1989/06

°ê¥ß¶§©ú¤j¾Ç ¡X Âå¾Ç§Þ³N¾Ç¨t(²¦) ¡X ¾Ç¤h

Bachelor, Department of Medical Technology, National Yang Ming University

1982/09 ¡X 1986/06

 Intramural Experience

Office/Department/Institute Position Duration
¥Í©R¬ì¾Ç°|¾Ç¤h¯Z   Director 2024/08/01 ¡X 2025/07/31
¥Í©R¬ì¾Ç°|ÂåÃĤƾǺ[¥Íª«¬ì§ÞºÓ¤h¯Z Master's Program in Medicinal Chemistry & Biotechnology   Director 2024/08/01 ¡X 2025/07/31
¥Í©R¬ì¾Ç³Õ¤h¾Ç¦ì¾Çµ{ PhD Degree Program in Life Sciences   Chair 2024/08/01 ¡X 2025/07/31
¥Íª«Âå¾Çº[Àô¹Ò¥Íª«¾Ç¨t Department of Biomedical Science and Environmental Biology   Associate Professor 2021/08/01 ¡X  
¥Í©R¬ì¾Ç°|¾Ç¤h¯Z   Associate Professor 2020/08/01 ¡X 2021/07/31
¥Íª«Âå¾Çº[Àô¹Ò¥Íª«¾Ç¨t Department of Biomedical Science and Environmental Biology   Associate Professor 2017/02/01 ¡X 2020/07/31
¥Íª«Âå¾Çº[Àô¹Ò¥Íª«¾Ç¨t Department of Biomedical Science and Environmental Biology   Assistant Professor 2011/08/01 ¡X 2017/01/31
¥Íª«¬ì§Þ¾Ç¨t Department of Biotechnology   Assistant Professor 2011/02/01 ¡X 2011/07/31
¥Íª«Âå¾Çº[Àô¹Ò¥Íª«¾Ç¨t Department of Biomedical Science and Environmental Biology   Assistant Professor 2003/08/01 ¡X 2011/01/31
¥Íª«¾Ç¨t Department of Biology   Assistant Professor 1997/08/01 ¡X 2003/07/31

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 ¥Íª«Âå¹AÃþ Biology, Medicine and Agriculture Âå¾Ç¤§¥Í¤Æ¤Î¤À¤l¥Íª« Medical Biochemistry and Molecular Biology
2 ¥Íª«Âå¹AÃþ Biology, Medicine and Agriculture ·L¥Íª«¤Î§K¬Ì¾Ç Microbiology and Immunology

 Research & Technology Platform Open to the Outside

DNA methylation analysis

 Interested Area(s)for Interdisciplinary Research

ªíÆ[°ò¦]¤ÎÀù¯g¥Íª«¾Ç¬ã¨s

Epigenetic study and cancer biology

 Area(s) of Expertise & Research

¸~½F¥Íª« ¯f¬r¾Ç °ò¦]¥Ò°ò¤Æ

cancer biology virology DNA methylation

 Publication

NO Publication
1

NLRP3 Gene Polymorphisms in Rheumatoid Arthritis and Primary Sjogren's Syndrome Patients.
§õ·ç¦~, ¼ÚÀéÄË#, ªL¹Å¼z, ªL­ì¥ü, ¤è«º»T, ³¯©Éµ×, ´¿®aÂ@, §º°û·ì, §d¥¿´Ü, ÃC¥¿½å* - - 1 - DIAGNOSTICS (BASEL, SWITZERLAND) - DIAGNOSTICS 2023 13¨÷(2´Á):206­¶
(IF: 3.6, »â°ì±Æ¦W: 63, »â°ì´Á¥Z¼Æ: 167, »â°ì±Æ¦W: 37.72%)

NLRP3 Gene Polymorphisms in Rheumatoid Arthritis and Primary Sjogren's Syndrome Patients.
Ruei-Nian Li, Tsan-Teng Ou#, Chia-Hui Lin, Yuan-Zhao Lin, Tzu-Jung Fang, Yi-Jing Chen, Chia-Chun Tseng, Wan-Yu Sung, Cheng-Chin Wu, Jeng-Hsien Yen - - 1 - DIAGNOSTICS (BASEL, SWITZERLAND) - DIAGNOSTICS 2023;13(2):206
(IF: 3.6, Journal Ranking: 63, Number of Journals of this Field: 167, Ranking: 37.72%)

2

A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy.
§f­}¤h, ±i¤åÀé, ¬_´º¤¤, §õ·ç¦~, ·¨´f¶{, ³¯«Å¦ö, ¶ÀµY¶®, ±i¹Ú´­*, Chang-Yi Wu, ªô«Ø´¼* - - 1 - LIFE SCIENCES - LIFE SCIENCES 2023 329¨÷(-´Á):121835­¶
(IF: 6.1, »â°ì±Æ¦W: 35, »â°ì´Á¥Z¼Æ: 277, »â°ì±Æ¦W: 12.64%)

A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy.
Ritesh Urade, Wen-Tsan Chang, Ching-Chung Ko, Ruei-Nian Li, Hui-Min Yang, Hsuan-Yu Chen, Lin-Ya Huang, Meng-Yang Chang*, Chang-Yi Wu*, Chien-Chih Chiu* - - 1 - LIFE SCIENCES - LIFE SCIENCES 2023;329(-):121835
(IF: 6.1, Journal Ranking: 35, Number of Journals of this Field: 277, Ranking: 12.64%)

3

A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
Àj¥Ã©w, ¬_´º¤¤, ±i¤åÀé, ªô¶h²[, ¬x¬K«º, ¶À¬L¬Â, ´¿§ÓµØ, ³¯¸qÀs*, §õ·ç¦~*, ªô«Ø´¼* - - 1 - CANCER CELL INTERNATIONAL - CANCER CELL INTERNATIONAL 2023 23¨÷(1´Á):171­¶
(IF: 5.3, »â°ì±Æ¦W: 61, »â°ì´Á¥Z¼Æ: 322, »â°ì±Æ¦W: 18.94%)

A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
Yung-Ding Bow, Ching-Chung Ko, Wen-Tsan Chang, Sih-Yan Chou, Chun-Tzu Hung, Jau-Ling Huang, Chih-Hua Tseng, Yeh-Long Chen*, Ruei-Nian Li*, Chien-Chih Chiu* - - 1 - CANCER CELL INTERNATIONAL - CANCER CELL INTERNATIONAL 2023;23(1):171
(IF: 5.3, Journal Ranking: 61, Number of Journals of this Field: 322, Ranking: 18.94%)

4

Lower HDAC6 mRNA expression and promoter hypomethylation are associated with RA susceptibility.
¤è«º»T, ªL¹Å¼z, ªL­ì¥ü, MH Chiu, §õ·ç¦~, ¸âµØã¸, YT Yeh*, ÃC¥¿½å* - - 1 - JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION - JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION 2022 121¨÷(8´Á):1431-1441­¶
(IF: 3.871, »â°ì±Æ¦W: 61, »â°ì´Á¥Z¼Æ: 172, »â°ì±Æ¦W: 35.47%)

Lower HDAC6 mRNA expression and promoter hypomethylation are associated with RA susceptibility.
Tzu-Jung Fang, Chia-Hui Lin, Yuan-Zhao Lin, Min-HSi Chiu, Ruei-Nian Li, Hua-Chen Chan, Yao-Tsung Yeh*, Jeng-Hsien Yen* - - 1 - JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION - JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION 2022;121(8):1431-1441
(IF: 3.871, Journal Ranking: 61, Number of Journals of this Field: 172, Ranking: 35.47%)

5

Genetic and epigenetic alterations of cyclic AMP response element modulator in rheumatoid arthritis.
´¿®aÂ@, ªL­ì¥ü, ªL¹Å¼z,¶À¹D´­,§õ·ç¦~, Wen-Chan Tsai, ¼ÚÀéÄË, §d¥¿´Ü, ªL¨|§Ó, §º°û·ì, ³¯«a¦t, ³¹¶¶¤¯*, ÃC¥¿½å* - - 1 - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2022 52¨÷(5´Á):e13715­¶
(IF: 5.722, »â°ì±Æ¦W: 39, »â°ì´Á¥Z¼Æ: 172, »â°ì±Æ¦W: 22.67%)

Genetic and epigenetic alterations of cyclic AMP response element modulator in rheumatoid arthritis.
Chia-Chun Tseng, Yuan-Zhao Lin, Chia-Hui Lin, Daw-Yang Hwang, Ruei-Nian Li, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Yu-Chih Lin, Wan-Yu Sung, Kuan-Yu Chen, Shun-Jen Chang*, Jeng-Hsien Yen* - - 1 - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2022;52(5):e13715
(IF: 5.722, Journal Ranking: 39, Number of Journals of this Field: 172, Ranking: 22.67%)

6

Methylation of TET2 Promoter Is Associated with Global Hypomethylation and Hypohydroxymethylation in Peripheral Blood Mononuclear Cells of Systemic Lupus Erythematosus Patients
§º°û·ì*,ªL­ì¥ü,¶À¹D´­, ªL¹Å¼z,§õ·ç¦~,´¿®aÂ@,§d¥¿´Ü,¼ÚÀéÄË,ÃC¥¿½å* - - 1 - Diagnostics - DIAGNOSTICS 2022 12¨÷(12´Á):3006­¶
(IF: 3.992, »â°ì±Æ¦W: 60, »â°ì´Á¥Z¼Æ: 172, »â°ì±Æ¦W: 34.88%)

Methylation of TET2 Promoter Is Associated with Global Hypomethylation and Hypohydroxymethylation in Peripheral Blood Mononuclear Cells of Systemic Lupus Erythematosus Patients
Wan-Yu Sung* ,Yuan-Zhao Lin ,Daw-Yang Hwang, Chia-Hui Lin ,Ruei-Nian Li ,Chia-Chun Tseng,Cheng-Chin Wu ,Tsan-Teng Ou ,Jeng-Hsien Yen* - - 1 - Diagnostics - DIAGNOSTICS 2022;12(12):3006
(IF: 3.992, Journal Ranking: 60, Number of Journals of this Field: 172, Ranking: 34.88%)

7

Vancomycin Functionalization of Gold Nanostars for Sensitive Detection of Foodborne Pathogens through Surface¡Venhanced Raman Scattering
Dayalan S, Gedda G, §õ·ç¦~, Zulfajri M, ¶À«T¾Æ* - - 1 - Journal of Chinese Chemical Society - JOURNAL OF THE CHINESE CHEMICAL SOCIETY 2022 69¨÷(12´Á):2049-2060­¶
(IF: 1.753, »â°ì±Æ¦W: 135, »â°ì´Á¥Z¼Æ: 179, »â°ì±Æ¦W: 75.42%)

Vancomycin Functionalization of Gold Nanostars for Sensitive Detection of Foodborne Pathogens through Surface¡Venhanced Raman Scattering
Sandhiya Dayalan, Gangaraju Gedda, Ruei¡VNian Li, Muhammad Zulfajri, Genin Gary Huang* - - 1 - Journal of Chinese Chemical Society - JOURNAL OF THE CHINESE CHEMICAL SOCIETY 2022;69(12):2049-2060
(IF: 1.753, Journal Ranking: 135, Number of Journals of this Field: 179, Ranking: 75.42%)

8

A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways.
±i¤åÀé, Àj¥Ã©w, ³Å¨Ø»T, §õ¨Î¶§, §dªø¯q, ±i¤A¾ì, ¾H¿P©g, §õ·ç¦~, §f¬ü¬z, ¼B¯q©÷*, ªô«Ø´¼* (¦@¦P³q°T§@ªÌ) - - 1 - Oxidative medicine and cellular longevity - OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2021 2021¨÷(0´Á):7689045­¶
(IF: 7.31, »â°ì±Æ¦W: 55, »â°ì´Á¥Z¼Æ: 194, »â°ì±Æ¦W: 28.35%)

A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways.
Wen-Tsan Chang, Yung-Ding Bow, Pei-Jung Fu, Chia-Yang Li, Chang-Yi Wu, Yi-Hua Chang, Yen-Ni Teng, Ruei-Nian Li, Mei-Chin Lu, Yi-Chang Liu*, Chien-Chih Chiu* (co-corresponding author) - - 1 - Oxidative medicine and cellular longevity - OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2021;2021(0):7689045
(IF: 7.31, Journal Ranking: 55, Number of Journals of this Field: 194, Ranking: 28.35%)

9

Association of F11R polymorphisms and gene expression with primary Sjögren's syndrome patients.
¤è«º»T,§õ·ç¦~#,ªL­ì¥ü,ªL¹Å¼z,´¿®aÂ@,§º°û·ì,¼ÚÀéÄË,§d¥¿´Ü,ÃC¥¿½å* - - 1 - International journal of rheumatic diseases - INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES 2021 24¨÷(5´Á):681-686­¶
(IF: 2.454, »â°ì±Æ¦W: 28, »â°ì´Á¥Z¼Æ: 34, »â°ì±Æ¦W: 82.35%)

Association of F11R polymorphisms and gene expression with primary Sjögren's syndrome patients.
Tzu-Jung Fang,Ruei-Nian Li#,Yuan-Zhao Lin,Chia-Hui Lin,Chia-Chun Tseng,Wan-Yu Sung,Tsan-Teng Ou,Cheng-Chin Wu,Jeng-Hsien Yen* - - 1 - International journal of rheumatic diseases - INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES 2021;24(5):681-686
(IF: 2.454, Journal Ranking: 28, Number of Journals of this Field: 34, Ranking: 82.35%)

10

A novel CD209 polymorphism is associated with rheumatoid arthritis patients in Taiwan.
¸âµØã¸,¤ý²Q¬Ã#,ªL¹Å¼z,ªL­ì¥ü,§õ·ç¦~,ÃC¥¿½å* - - 1 - Journal of clinical laboratory analysis - JOURNAL OF CLINICAL LABORATORY ANALYSIS 2021 35¨÷(5´Á):e23751­¶
(IF: 2.352, »â°ì±Æ¦W: 15, »â°ì´Á¥Z¼Æ: 29, »â°ì±Æ¦W: 51.72%)

A novel CD209 polymorphism is associated with rheumatoid arthritis patients in Taiwan.
Hua-Chen Chan, Shu-Chen Wang#, Chia-Hui Lin, Yuan-Zhao Lin, Ruei-Nian Li, Jeng-Hsien Yen* - - 1 - Journal of clinical laboratory analysis - JOURNAL OF CLINICAL LABORATORY ANALYSIS 2021;35(5):e23751
(IF: 2.352, Journal Ranking: 15, Number of Journals of this Field: 29, Ranking: 51.72%)

11

The Phenoxyphenol Compound diTFPP Mediates Exogenous C2-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells.
±i¤åÀé, Àj¥Ã©w#, ³¯ø@§g, §õ¨Î¶§, ³¯¶h¤Ò, ¦¶«³ÀR, ¾H¿P©g, §õ·ç¦~, ªô«Ø´¼* - - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2021 10¨÷(3´Á):394­¶
(IF: 7.675, »â°ì±Æ¦W: 4, »â°ì´Á¥Z¼Æ: 63, »â°ì±Æ¦W: 6.35%)

The Phenoxyphenol Compound diTFPP Mediates Exogenous C2-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells.
Wen-Tsan Chang, Yung-Ding Bow#, Yen-Chun Chen, Chia-Yang Li, Jeff Yi-Fu Chen, Yi-Ching Chu, Yen-Ni Teng, Ruei-Nian Li, Chien-Chih Chiu* - - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2021;10(3):394
(IF: 7.675, Journal Ranking: 4, Number of Journals of this Field: 63, Ranking: 6.35%)

12

MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner.
¨Lµx¶³,³¯¥É©ø,StevenLo,¬ö©v¨°,³¯©ÉµØ,­J·¡ªQ,³¯¶®¶²,¦¿¤hª@,½²ªÚ·ì,¼B©ô¹F,§õ·ç¦~,Á¶®´¹,¶À§Ó¤¯,°K¦æ­×* - - 1 - Oncogene - ONCOGENE 2021 40¨÷(20´Á):3510-3532­¶
(IF: 9.867, »â°ì±Æ¦W: 29, »â°ì´Á¥Z¼Æ: 298, »â°ì±Æ¦W: 9.73%)

MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner.
Yen-Yun Wang, Yuk-Kwan Chen, Steven Lo, Tsung-Chen Chi, Yi-Hua Chen, Stephen Chu-Sung Hu, Ya-Wen Chen, Shih Sheng Jiang, Fang-Yu Tsai, Wangta Liu, Ruei-Nian Li, Ya-Ching Hsieh, Chih-Jen Huang, Shyng-Shiou F Yuan* - - 1 - Oncogene - ONCOGENE 2021;40(20):3510-3532
(IF: 9.867, Journal Ranking: 29, Number of Journals of this Field: 298, Ranking: 9.73%)

13

Oxidative Stress-Dependent Synergistic Antiproliferation, Apoptosis, and DNA Damage of Ultraviolet-C and Coral-Derived Sinularin Combined Treatment for Oral Cancer Cells.
´^¸t³ó#, ´ö¤H¥õ#, §õ·ç¦~, ¶À¥°¤å, §dªø¯q, ªô«Ø´¼, ±iªÚºa, Hong-Wei Zhang, §õ©û¬X, ³\§Ó§»*, ±i¾Ç°¶* - - 1 - Cancers - CANCERS 2021 13¨÷(10´Á):2450­¶
(IF: 6.575, »â°ì±Æ¦W: 60, »â°ì´Á¥Z¼Æ: 245, »â°ì±Æ¦W: 24.49%)

Oxidative Stress-Dependent Synergistic Antiproliferation, Apoptosis, and DNA Damage of Ultraviolet-C and Coral-Derived Sinularin Combined Treatment for Oral Cancer Cells.
Sheng-Yao Peng, Jen-Yang Tang, Ruei-Nian Li, Hurng-Wern Huang, Chang-Yi Wu, Chien-Chih Chiu, Fang-Rong Chang, Hong-Wei Zhang,Yun-Jou Lee, Jyh-Horng Sheu*, Hsueh-Wei Chang* - - 1 - Cancers - CANCERS 2021;13(10):2450
(IF: 6.575, Journal Ranking: 60, Number of Journals of this Field: 245, Ranking: 24.49%)

14

Comparison of Antioxidant and Anticancer Properties of Soft Coral-Derived Sinularin and Dihydrosinularin.
¤ý¸t³Ç, §õ·ç¦~, ªL¥ß«C, ´ö¤H¥õ, Ĭ·çªY, ³\§Ó§»*, ±i¾Ç°¶* - - 1 - Molecules (Basel, Switzerland) - MOLECULES 2021 26¨÷(13´Á):3853­¶
(IF: 4.927, »â°ì±Æ¦W: 65, »â°ì´Á¥Z¼Æ: 179, »â°ì±Æ¦W: 36.31%)

Comparison of Antioxidant and Anticancer Properties of Soft Coral-Derived Sinularin and Dihydrosinularin.
Sheng-Chieh Wang, Ruei-Nian Li, Li-Ching Lin, Jen-Yang Tang, Jui-Hsin Su, Jyh-Horng Sheu*, Hsueh-Wei Chang* - - 1 - Molecules (Basel, Switzerland) - MOLECULES 2021;26(13):3853
(IF: 4.927, Journal Ranking: 65, Number of Journals of this Field: 179, Ranking: 36.31%)

15

Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer
Àj¥Ã©w#, ¨Lµx¶³#, ³¯¥É©ø, ĬÎëÞ³, ³\¸g°¶, ¿½ºð»ö, °K¦æ­×*, §õ·ç¦~* - - 1 - oral diseases - ORAL DISEASES 2020 26¨÷(4´Á):756-765­¶
(IF: 2.613, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 91, »â°ì±Æ¦W: 20.88%)

Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer
Yung‐Ding Bow#, Yen‐Yun Wang#, Yuk‐Kwan Chen, Chang‐Wei Su, Ching‐Wei Hsu, Ling‐yi Xiao, Shyng‐Shiou Yuan*, Ruei‐Nian Li* - - 1 - oral diseases - ORAL DISEASES 2020;26(4):756-765
(IF: 2.613, Journal Ranking: 19, Number of Journals of this Field: 91, Ranking: 20.88%)

16

Genetic and Epigenetic Alteration of the Programmed Cell Death 1 (PDCD1) in Rheumatoid Arthritis
´¿®aÂ@, ªL­ì¥ü, ªL¹Å¼z, §õ·ç¦~, ½²¤å®i, ¼ÚÀéÄË, §d¥¿´Ü, §º°û·ì, ÃC¥¿½å* - - 1 - Eur J Clin Invest - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2019 49¨÷(10´Á):e13094­¶
(IF: 2.784, »â°ì±Æ¦W: 37, »â°ì´Á¥Z¼Æ: 160, »â°ì±Æ¦W: 23.13%)

Genetic and Epigenetic Alteration of the Programmed Cell Death 1 (PDCD1) in Rheumatoid Arthritis
Tseng CC, Lin YC, Lin CH, Li RN, Tsai WC, Ou TT, Wu CC, Sung WY, Yen JH* - - 1 - Eur J Clin Invest - EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 2019;49(10):e13094
(IF: 2.784, Journal Ranking: 37, Number of Journals of this Field: 160, Ranking: 23.13%)

17

GADD45a and GADD45b Genes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients
§õ·ç¦~, ªL­ì¥ü, Ya-Chun Pan, ªL¹Å¼z, ´¿®aÂ@, §º°û·ì, §d¥¿´Ü, ¼ÚÀéÄË, ½²¤å®i, ÃC¥¿½å* - - 1 - Journal of Clinical Medicine - JOURNAL OF CLINICAL MEDICINE 2019 8¨÷(6´Á):801­¶
(IF: 5.688, »â°ì±Æ¦W: 15, »â°ì´Á¥Z¼Æ: 160, »â°ì±Æ¦W: 9.38%)

GADD45a and GADD45b Genes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients
Ruei-Nian Li, Yuan-Zhao Lin, Ya-Chun Pan, Chia-Hui Lin, Chia-Chun Tseng, Wan-Yu Sung, Cheng-Chin Wu, Tsan-Teng Ou, Wen-Chan Tsai and Jeng-Hsien Yen* - - 1 - Journal of Clinical Medicine - JOURNAL OF CLINICAL MEDICINE 2019;8(6):801
(IF: 5.688, Journal Ranking: 15, Number of Journals of this Field: 160, Ranking: 9.38%)

18

Combination Therapy of Chloroquine and C2-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells
©P¿«ªL,ªL¶hµ¾,¼B©ô¹F,§dªø¯q,§õ·ç¦~,¶À¥°¤å,©P©u½å,ªôÅã»F,ªô«Ø´¼* - - 1 - Cancers - CANCERS 2019 11¨÷(3´Á):370­¶
(IF: 6.126, »â°ì±Æ¦W: 37, »â°ì´Á¥Z¼Æ: 244, »â°ì±Æ¦W: 15.16%)

Combination Therapy of Chloroquine and C2-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells
Han-Lin Chou†, Yi-Hsiung Lin†, Wangta Liu, Chang-Yi Wu, Ruei-Nian Li, Hurng-Wern Huang, Chi-Hsien Chou, Shean-Jaw Chiou, Chien-Chih Chiu* - - 1 - Cancers - CANCERS 2019;11(3):370
(IF: 6.126, Journal Ranking: 37, Number of Journals of this Field: 244, Ranking: 15.16%)

19

Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis.
´¿®aÂ@, ªL­ì¥ü, ªL¹Å¼z, §õ·ç¦~, Yen CY, ¸âµØã¸, ½²¤å®i, ¼ÚÀéÄË, §d¥¿´Ü, §º°û·ì, ÃC¥¿½å* - - 1 - J Clin Med - JOURNAL OF CLINICAL MEDICINE 2019 8¨÷(9´Á):1284­¶
(IF: 5.688, »â°ì±Æ¦W: 15, »â°ì´Á¥Z¼Æ: 160, »â°ì±Æ¦W: 9.38%)

Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis.
Tseng CC, Lin YC, Lin CH, Li RN, Yen CY, Chan HC, Tsai WC, Ou TT, Wu CC, Sung WY, Yen JH*. - - 1 - J Clin Med - JOURNAL OF CLINICAL MEDICINE 2019;8(9):1284
(IF: 5.688, Journal Ranking: 15, Number of Journals of this Field: 160, Ranking: 9.38%)

20

Reactive oxygen species mediate soft corals-derived sinuleptolide-induced antiproliferation and DNA damage in oral cancer cells
Yung-Ting Chang#, Chiung-Yao Huang#, §õ·ç¦~, ¹ù§Ó¤¤, ¼BÀR¦p, ³\§Ó§»*, ±i¾Ç°¶* - - 1 - Onco Targets Ther - 2017 10¨÷(1´Á):3289-3297­¶
(IF: 2.612, »â°ì±Æ¦W: 61, »â°ì´Á¥Z¼Æ: 160, »â°ì±Æ¦W: 38.13%)

Reactive oxygen species mediate soft corals-derived sinuleptolide-induced antiproliferation and DNA damage in oral cancer cells
Yung-Ting Chang#, Chiung-Yao Huang#, Ruei-Nian Li, Chih-Chuang Liaw, Jing-Ru Liu, Jyh-Horng Sheu*, Hsueh-Wei Chang* - - 1 - Onco Targets Ther - 2017;10(1):3289-3297
(IF: 2.612, Journal Ranking: 61, Number of Journals of this Field: 160, Ranking: 38.13%)

21

Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells.
±i¾Ç°¶,§õ·ç¦~, ¤ý¼z¦p, ¼BÀR¦p,´ö¤H¥õ, ¶À¥°¤å,¸â«Bæ¢, Ching-Yu Yen* - - 1 - Frontiers in Physiology - FRONT PHYSIOL 2017 8¨÷(1´Á):643­¶
(IF: 4.134, »â°ì±Æ¦W: 15, »â°ì´Á¥Z¼Æ: 84, »â°ì±Æ¦W: 17.86%)

Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells.
Hsueh-Wei Chang, Ruei-Nian Li, Hui-Ru Wang, Jing-Ru Liu, Jen-Yang Tang, Hurng-Wern Huang, Yu-Hsuan Chan, Ching-Yu Yen* - - 1 - Frontiers in Physiology - FRONT PHYSIOL 2017;8(1):643
(IF: 4.134, Journal Ranking: 15, Number of Journals of this Field: 84, Ranking: 17.86%)

22

Promoter methylation status of tumor suppressor genes p16 and CDH1 in cervical intraepithelial Neoplasia.
§õ·ç¦~, Li CY, §õ«Ø§»,´^ã·ì, §d©ú»a* - - 1 - Oncology Letters - Oncol Lett 2017 13¨÷(6´Á):4397-4401­¶
(IF: 1.39, »â°ì±Æ¦W: 192, »â°ì´Á¥Z¼Æ: 217, »â°ì±Æ¦W: 88.48%)

Promoter methylation status of tumor suppressor genes p16 and CDH1 in cervical intraepithelial Neoplasia.
Li RN, Li CY, Lee CH, Peng CY, Wu MT* - - 1 - Oncology Letters - Oncol Lett 2017;13(6):4397-4401
(IF: 1.39, Journal Ranking: 192, Number of Journals of this Field: 217, Ranking: 88.48%)

23

Ãþ­··Ã©ÊÃö¸`ª¢¯f¤H¤§F11R °ò¦]ªí²{¤Î°ò¦]¦h§Î©Ê
¤è«º»T, ªL¹Å¼z, ªL­ì¥ü, §õ·ç¦~, ¼ÚÀéÄË, §d¥¿´Ü, ½²¤å®i, ÃC¥¿½å* - - 1 - International Journal of Rheumatic Diseases - INT J RHEUM DIS 2016 19¨÷(2´Á):127-133­¶
(IF: 1.914, »â°ì±Æ¦W: 21, »â°ì´Á¥Z¼Æ: 32, »â°ì±Æ¦W: 65.63%)

F11R mRNA expression and promoter polymorphisms in pateints with rheumatoid arthritis.
Tzu-Jung Fang, Chia-hui Lin, Yuan-Zhao Lin, Ruei-Nian Li, Tsan-Teng Ou, Cheng-Chin Wu, Wen-Chan Tsai and Jeng-Hsien Yen*. - - 1 - International Journal of Rheumatic Diseases - INT J RHEUM DIS 2016;19(2):127-133
(IF: 1.914, Journal Ranking: 21, Number of Journals of this Field: 32, Ranking: 65.63%)

24

Methylation and gene expression of histone deacetylases 6 in systemic lupus erythematosus.
¤è«º»T, ªL­ì¥ü, ¼BÀRµ×, ªL¹Å¼z, §õ·ç¦~, §d¥¿´Ü, ¼ÚÀéÄË, ½²¤å®i, ÃC¥¿½å* - - 1 - International Journal of Rheumatic Diseases - INT J RHEUM DIS 2016 19¨÷(10´Á):968-973­¶
(IF: 1.914, »â°ì±Æ¦W: 21, »â°ì´Á¥Z¼Æ: 32, »â°ì±Æ¦W: 65.63%)

Methylation and gene expression of histone deacetylases 6 in systemic lupus erythematosus.
Tzu-Jung Fang, Yuan-Zhao Lin, Ching-Ching Liu, Chia-Hui Lin, Reui-Nian Li, Cheng-Chin Wu, Tsan-Teng Ou, Wen-Chan Tsai and Jeng-Hsien Yen* - - 1 - International Journal of Rheumatic Diseases - INT J RHEUM DIS 2016;19(10):968-973
(IF: 1.914, Journal Ranking: 21, Number of Journals of this Field: 32, Ranking: 65.63%)

25

Risk evaluation for the development of cervical intraepithelial neoplasia: Development and validation of risk-scoring schemes.
§õ«Ø§»,´^ã·ì,§õ·ç¦~,³¯´ü¼ä,½²¨q´@,¬x¤_Öq, ¸â¼w´I, Huang HL,¿à®õ¥à ,§d©ú»a* - - 1 - INTERNATIONAL JOURNAL OF CANCER - INT J CANCER 2015 136¨÷(2´Á):340-349­¶
(IF: 5.085, »â°ì±Æ¦W: 31, »â°ì´Á¥Z¼Æ: 211, »â°ì±Æ¦W: 14.69%)

Risk evaluation for the development of cervical intraepithelial neoplasia: Development and validation of risk-scoring schemes.
Chien-Hung Lee, Chiung-Yu Peng, Ruei-Nian Li, Yu-Chieh Chen, Hsiu-Ting Tsai, Yu-Hsiu Hung, Te-Fu Chan, Hsiao-Ling Huang, Tai-Cheng Lai, Ming-Tsang Wu* - - 1 - INTERNATIONAL JOURNAL OF CANCER - INT J CANCER 2015;136(2):340-349
(IF: 5.085, Journal Ranking: 31, Number of Journals of this Field: 211, Ranking: 14.69%)

26

Activation and inhibition of ATM by phytochemicals: awakening and sleeping the guardian angel naturally
Ammad Ahmad Farooqi, §d¥@©¾, ±iµú´@, ´ö¤H¥õ, §õûi·O, Muhammad Ismail, Chih-Chuang Liaw, §õ·ç¦~*, ±i¾Ç°¶* - - 1 - ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS - ARCH IMMUNOL THER EX 2015 63¨÷(5´Á):357-366­¶
(IF: 3.176, »â°ì±Æ¦W: 60, »â°ì´Á¥Z¼Æ: 148, »â°ì±Æ¦W: 40.54%)

Activation and inhibition of ATM by phytochemicals: awakening and sleeping the guardian angel naturally
Ammad Ahmad Farooqi, Shyh-Jong Wu, Yung-Ting Chang, Jen-Yang Tang, Kun-Tzu Li, Muhammad Ismail, Chih-Chuang Liaw, Ruei-Nian Li*, Hsueh-Wei Chang* - - 1 - ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS - ARCH IMMUNOL THER EX 2015;63(5):357-366
(IF: 3.176, Journal Ranking: 60, Number of Journals of this Field: 148, Ranking: 40.54%)

27

Natural products mediated regulation of oxidative stress and DNA damage in ultraviolet exposed skin cells
Ammad Ahmad Farooqi, §õ·ç¦~, Hurng-Wern Huang, Muhammad Ismail, °K¦æ­×, ¤ý´f¥Á, ¼BÀR¦p, ´ö¤H¥õ*, ±i¾Ç°¶* - - 1 - CURRENT PHARMACEUTICAL BIOTECHNOLOGY - CURR PHARM BIOTECHNO 2015 16¨÷(12´Á):1078-1084­¶
(IF: 1.95, »â°ì±Æ¦W: 152, »â°ì´Á¥Z¼Æ: 255, »â°ì±Æ¦W: 59.61%)

Natural products mediated regulation of oxidative stress and DNA damage in ultraviolet exposed skin cells
Ammad Ahmad Farooqi, Ruei-Nian Li, Hurng-Wern Huang, Muhammad Ismail, Shyng-Shiou F. Yuan, Hui-Min David Wang, Jing-Ru Liu, Jen-Yang Tang*, Hsueh-Wei Chang* - - 1 - CURRENT PHARMACEUTICAL BIOTECHNOLOGY - CURR PHARM BIOTECHNO 2015;16(12):1078-1084
(IF: 1.95, Journal Ranking: 152, Number of Journals of this Field: 255, Ranking: 59.61%)

28

Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers
Ammad Ahmad Farooqi, ´ö¤H¥õ, §õ·ç¦~, Muhammad Ismail, ±iµú´@, Chih-Wen Shu, °K¦æ­×, ¼BÀR¦p, ¶À§Ó¤¯*, ±i¾Ç°¶* - - 1 - International Journal of Nanomedicine - INT J NANOMED 2015 10¨÷(-´Á):3183-3191­¶
(IF: 4.383, »â°ì±Æ¦W: 30, »â°ì´Á¥Z¼Æ: 255, »â°ì±Æ¦W: 11.76%)

Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers
Ammad Ahmad Farooqi, Jen-Yang Tang, Ruei-Nian Li, Muhammad Ismail, Yung-Ting Chang, Chih-Wen Shu, Shyng-Shiou F. Yuan, Jing-Ru Liu, Chih-Jen Huang*, Hsueh-Wei Chang* - - 1 - International Journal of Nanomedicine - INT J NANOMED 2015;10(-):3183-3191
(IF: 4.383, Journal Ranking: 30, Number of Journals of this Field: 255, Ranking: 11.76%)

29

Alternative splicing, DNA damage, and modulating drugs in radiation therapy for cancer
´ö¤H¥õ, §õ·ç¦~, ³¯¤þ¦ó, Hurng-Wern Huang, «J©ú¾W*, ±i¾Ç°¶* - - 1 - Anti-Cancer Agents in Medicinal Chemistry - ANTI-CANCER AGENT ME 2015 15¨÷(6´Á):674-680­¶
(IF: 2.469, »â°ì±Æ¦W: 29, »â°ì´Á¥Z¼Æ: 59, »â°ì±Æ¦W: 49.15%)

Alternative splicing, DNA damage, and modulating drugs in radiation therapy for cancer
Jen-Yang Tang, Ruei-Nian Li, Ping-Ho Chen, Hurng-Wern Huang, Ming-Feng Hou*, Hsueh-Wei Chang* - - 1 - Anti-Cancer Agents in Medicinal Chemistry - ANTI-CANCER AGENT ME 2015;15(6):674-680
(IF: 2.469, Journal Ranking: 29, Number of Journals of this Field: 59, Ranking: 49.15%)

30

iridium(III) ½Æ¦Xª«§Üµß¤Î§ÜÀù¬¡©Ê¬ã¨s
Lihua Lu, Li-Juan Liu, Wei-chieh Chao, Hai-Jing Zhong, Modi Wang, Xiu-Ping Chen, Jin-Jian Lu, Ruei-nian Li*, §õ·ç¦~*, Dik-Lung Ma, Chung-Hang Leung - - 1 - Scientific Reports - SCI REP-UK 2015 5¨÷(9´Á):14544­¶
(IF: 5.578, »â°ì±Æ¦W: 5, »â°ì´Á¥Z¼Æ: 57, »â°ì±Æ¦W: 8.77%)

Identification of an iridium (III) complesx with anti-bacterial and anti-cancer activity
Lihua Lu, Li-Juan Liu, Wei-chieh Chao, Hai-Jing Zhong, Modi Wang, Xiu-Ping Chen, Jin-Jian Lu, Ruei-nian Li*, Dik-Lung Ma and Chung-Hang Leung - - 1 - Scientific Reports - SCI REP-UK 2015;5(9):14544
(IF: 5.578, Journal Ranking: 5, Number of Journals of this Field: 57, Ranking: 8.77%)

31

Ãþ­·Àã©ÊÃö¸`ª¢©M¥þ¨­©Ê¬õ´³©Ê¯T½HªºOSMR°ò¦]¦h«¬©Ê
ªL­ì¥ü, §õ·ç¦~(¦@¦P²Ä¤@), ªL¹Å¼z, ¼ÚÀéÄË, §d¥¿´Ü(1), ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - AUTOIMMUNITY - AUTOIMMUNITY 2014 47¨÷(1´Á):23-26­¶
(IF: 2.754, »â°ì±Æ¦W: 71, »â°ì´Á¥Z¼Æ: 144, »â°ì±Æ¦W: 49.31%)

Association of OSMR Gene Polymorphisms with Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients.
Lin YZ, Li RN, Lin CH, Ou TT, Wu CC, Tsai WC, Liu HW, Yen JH* - - 1 - AUTOIMMUNITY - AUTOIMMUNITY 2014;47(1):23-26
(IF: 2.754, Journal Ranking: 71, Number of Journals of this Field: 144, Ranking: 49.31%)

32

Methylation status of retinoic acid receptor beta2 promoter and global DNA in esophageal squamous cell carcinoma
§õ·ç¦~,§E¤èºa,§d«TªN,³¯¥É®Û,§E«TªN, ©P¥@µØ,§õ·ç­^,¾G¸Î¤¯,§d©ú»a,§d©y¬Ã* - - 1 - Journal of Surgical Oncology - J SURG ONCOL 2014 109¨÷(6´Á):623-627­¶
(IF: 2.843, »â°ì±Æ¦W: 34, »â°ì´Á¥Z¼Æ: 204, »â°ì±Æ¦W: 16.67%)

Methylation status of retinoic acid receptor beta2 promoter and global DNA in esophageal squamous cell carcinoma
Li RN, Yu FJ, Wu CC, Chen YK, Yu CC, Chou SH, Lee JY, Cheng YJ, Wu MT, Wu IC* - - 1 - Journal of Surgical Oncology - J SURG ONCOL 2014;109(6):623-627
(IF: 2.843, Journal Ranking: 34, Number of Journals of this Field: 204, Ranking: 16.67%)

33

Multiple single nucleotide polymorphisms associated with the susceptibility of pre-Diabetes Mellitus in a Taiwanese population(under review).
ªL¬îµâ,§õ·ç¦~ - - 0 - Disease marker American Journal of Medical Genetics. - 0 2014 0¨÷(0´Á):0­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Multiple single nucleotide polymorphisms associated with the susceptibility of pre-Diabetes Mellitus in a Taiwanese population(under review).
Lin, C.C., Lee, R. N* - - 0 - Disease marker American Journal of Medical Genetics. - 0 2014;0(0):0
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

34

Networks development between nicotinic chemical probes and Ca9-22 oral cancer cells by general proteomics analyses
§õ·ç¦~, Chin-Jen Wu, Zong-Jing Yu, ±i¾Ç°¶*,±ç¥@ªY* - - 1 - Electrophoresis - ELECTROPHORESIS 2014 35¨÷(15´Á):2213-2221­¶
(IF: 3.161, »â°ì±Æ¦W: 16, »â°ì´Á¥Z¼Æ: 76, »â°ì±Æ¦W: 21.05%)

Networks development between nicotinic chemical probes and Ca9-22 oral cancer cells by general proteomics analyses
Ruei-Nian Li, Chin-Jen Wu, Zong-Jing Yu, Hsueh-Wei Chang*, Shih-Shin Liang* - - 1 - Electrophoresis - ELECTROPHORESIS 2014;35(15):2213-2221
(IF: 3.161, Journal Ranking: 16, Number of Journals of this Field: 76, Ranking: 21.05%)

35

³æ®Ö²y»P SLC11A1 ¦h§Î©Ê¦b©Ü¦çµß©Ò¤Þ°_ªº¤ÏÀ³©ÊÃö¸`ª¢¤§­P¯f¾÷Âà¤W©Ò§êºtªº¨¤¦â
³¯©Éµ×, §õ·ç¦~, ªL¹Å¼z, ÃC¥¿½å* - - 1 - SCANDINAVIAN JOURNAL OF RHEUMATOLOGY - SCAND J RHEUMATOL 2013 42¨÷(2´Á):146-149­¶
(IF: 2.607, »â°ì±Æ¦W: 14, »â°ì´Á¥Z¼Æ: 30, »â°ì±Æ¦W: 46.67%)

The role of monocytes and SLC11A1 polymorphisms in the pathogenesis of Chlamydia-induced reactive arthritis.
Chen YJ, Li RN, Lin CH, Yen JH. - - 1 - SCANDINAVIAN JOURNAL OF RHEUMATOLOGY - SCAND J RHEUMATOL 2013;42(2):146-149
(IF: 2.607, Journal Ranking: 14, Number of Journals of this Field: 30, Ranking: 46.67%)

36

Global DNA Methylation, DNMT1, and MBD2 in Patients with Rheumatoid Arthritis
¤è«º»T,¼BÀRµ×(¦@¦P²Ä¤@), ¼ÚÀéÄË,§d¥¿´Ü,§õ·ç¦~,ªL­ì¥ü,ªL¹Å¼z,½²¤å®i,¼B§»¤å,ÃC¥¿½å* - - 1 - Immunology Letters - IMMUNOL LETT 2011 135¨÷(1-2´Á):96-99­¶
(IF: 2.511, »â°ì±Æ¦W: 77, »â°ì´Á¥Z¼Æ: 134, »â°ì±Æ¦W: 57.46%)

Global DNA Methylation, DNMT1, and MBD2 in Patients with Rheumatoid Arthritis
Liu CC, Fang TJ, Ou TT, Wu CC, Li RN, Lin YC, Lin CH, Tsai WC, Liu HW, Yen JH* - - 1 - Immunology Letters - IMMUNOL LETT 2011;135(1-2):96-99
(IF: 2.511, Journal Ranking: 77, Number of Journals of this Field: 134, Ranking: 57.46%)

37

Global DNA methylation, DNMT1, and MBD2 in patients with systemic lupus erythematosus
¼BÀRµ×, ¼ÚÀéÄË,§d¥¿´Ü,§õ·ç¦~,ªL­ì¥ü,ªL¹Å¼z,½²¤å®i,¼B§»¤å,ÃC¥¿½å* - - 1 - Lupus - LUPUS 2011 20¨÷(2´Á):131-136­¶
(IF: 2.6, »â°ì±Æ¦W: 14, »â°ì´Á¥Z¼Æ: 29, »â°ì±Æ¦W: 48.28%)

Global DNA methylation, DNMT1, and MBD2 in patients with systemic lupus erythematosus
Liu CC, Ou TT, Wu CC, Li RN, Lin YC, Lin CH, Tsai WC, Liu HW, Yen JH* - - 1 - Lupus - LUPUS 2011;20(2):131-136
(IF: 2.6, Journal Ranking: 14, Number of Journals of this Field: 29, Ranking: 48.28%)

38

Simultaneous Detection of Multiple Single Nucleotide Polymorphisms by a Simple Membrane Chip
Yu-Hsiang Yanga#, Ruei-Nian Lib#, Shey-Cherng Tzouh, Jaw-Yuan Wangc, Hsin-Pai Leed, Hsien-Chung Wangd, Fang-Ming Chenc, Yung-Hsin Wanga, Ming-Chia Hsieha, Ming-Yii Huange, Wei-Lung Tsengf, g, Shiu-Ru Linh, and Tian-Lu Cheng - - 1 - Genetic Testing and Molecular Biomarkers - GENET TEST MOL BIOMA 2011 14¨÷(5´Á):653-659­¶
(IF: 0.879, »â°ì±Æ¦W: 135, »â°ì´Á¥Z¼Æ: 156, »â°ì±Æ¦W: 86.54%)

Simultaneous Detection of Multiple Single Nucleotide Polymorphisms by a Simple Membrane Chip
Yu-Hsiang Yanga#, Ruei-Nian Lib#, Shey-Cherng Tzouh, Jaw-Yuan Wangc, Hsin-Pai Leed, Hsien-Chung Wangd, Fang-Ming Chenc, Yung-Hsin Wanga, Ming-Chia Hsieha, Ming-Yii Huange, Wei-Lung Tsengf, g, Shiu-Ru Linh, and Tian-Lu Cheng - - 1 - Genetic Testing and Molecular Biomarkers - GENET TEST MOL BIOMA 2011;14(5):653-659
(IF: 0.879, Journal Ranking: 135, Number of Journals of this Field: 156, Ranking: 86.54%)

39

¥þ¨­©Ê¬õ´³©Ê¯T½H¯f¤H¤§SOCS1°ò¦]ªí²{©M°ò¦]¦h§Î©Ê
¸âµØã¸, ¬_¨}­N, ±i¬ÂÄR, ¼BÀRµ×, ¬x·¶ÂE, ªL¹Å¼z, §õ·ç¦~, ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - Lupus - LUPUS 2010 19¨÷(6´Á):696-702­¶
(IF: 2.586, »â°ì±Æ¦W: 13, »â°ì´Á¥Z¼Æ: 26, »â°ì±Æ¦W: 50.00%)

Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus
HC Chan, LY Ke, LL Chang, CC Liu, YH Hung, CH Lin, RN Li, WC Tsai, HW Liu, JH Yen* - - 1 - Lupus - LUPUS 2010;19(6):696-702
(IF: 2.586, Journal Ranking: 13, Number of Journals of this Field: 26, Ranking: 50.00%)

40

¨©ÁɯS¤ó¯g­Ô¸s¯f¤HIkB£\°ò¦]ªº¦h§Î©Ê
¬x·¶ÂE, §d¥¿´Ü, ¼ÚÀéÄË, ªL¹Å¼z, §õ·ç¦~, ªL¨|§Ó, ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - Dis Markets. - DIS MARKERS 2010 28¨÷(1´Á):55-62­¶
(IF: 2.026, »â°ì±Æ¦W: 70, »â°ì´Á¥Z¼Æ: 150, »â°ì±Æ¦W: 46.67%)

IkappaBalpha promoter polymorphisms in patients with Behçet¡¦s disease
Hung YH, Wu CC, Ou TT, Lin CH, Li RN, Lin YC, Tsai WC, Liu HW, Yen JH*. - - 1 - Dis Markets. - DIS MARKERS 2010;28(1):55-62
(IF: 2.026, Journal Ranking: 70, Number of Journals of this Field: 150, Ranking: 46.67%)

41

Ãþ­·Àã©ÊÃö¸`ª¢¯f¤H¤§IkBalpha promoter¥\¯à¦h§Î©Ê
§õ·ç¦~, ¬x·¶ÂE, ªL¹Å¼z, ³¯«Û¦°, ÃC¥¿½å* - - 1 - Journal of Clinical Immunology - J CLIN IMMUNOL 2010 30¨÷(5´Á):676-680­¶
(IF: 3.326, »â°ì±Æ¦W: 48, »â°ì´Á¥Z¼Æ: 134, »â°ì±Æ¦W: 35.82%)

Inhibitor IkappaBalpha Promoter Functional Polymorphisms in Patients with Rheumatoid Arthritis
Li RN, Hung YH, Lin CH, Chen YH, Yen JH* - - 1 - Journal of Clinical Immunology - J CLIN IMMUNOL 2010;30(5):676-680
(IF: 3.326, Journal Ranking: 48, Number of Journals of this Field: 134, Ranking: 35.82%)

42

»øª½©Ê¯á´Õª¢¯f¤H¤§IkBalpha°ò¦]¦h§Î©Ê
¬x·¶ÂE, ¼ÚÀéÄË, ªL¹Å¼z, §õ·ç¦~, ªL¨|§Ó, ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - Rheunatol Int. - RHEUMATOL INT 2009 30¨÷(4´Á):93-97­¶
(IF: 1.327, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 22, »â°ì±Æ¦W: 86.36%)

IkBalpha promoter polymorphisms in patients with ankylosing spondylitis
Hung YH, Ou TT, Lin CH, Li RN, Lin YC, Tsai WC, Liu HW, Yen JH* - - 1 - Rheunatol Int. - RHEUMATOL INT 2009;30(4):93-97
(IF: 1.327, Journal Ranking: 19, Number of Journals of this Field: 22, Ranking: 86.36%)

43

¬õ´³©Ê¯T½H¯f¤H¤§IkB alpha°ò¦]¦h§Î©Ê
ªL¹Å¼z, ¤ý²Q¬Ã, ¼ÚÀéÄË, §õ·ç¦~, ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - J Clin Immunol - J CLIN IMMUNOL 2008 28¨÷(3´Á):207-213­¶
(IF: 3.248, »â°ì±Æ¦W: 44, »â°ì´Á¥Z¼Æ: 121, »â°ì±Æ¦W: 36.36%)

IkappaBalpha Promoter Polymorphisms in Patients with Systemic Lupus Erythematosus
Lin CH, Wang SC, Ou TT, Li RN, Tsai WC, Liu HW, Yen JH* - - 1 - J Clin Immunol - J CLIN IMMUNOL 2008;28(3):207-213
(IF: 3.248, Journal Ranking: 44, Number of Journals of this Field: 121, Ranking: 36.36%)

44

­ìµo©Ê°®Àê¯g¯f¤H¤§IkB alpha°ò¦]¦h§Î©Ê
¼ÚÀéÄË, ªL¹Å¼z, ªL¨|§Ó, §õ·ç¦~, ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - J Clin Immunol - J CLIN IMMUNOL 2008 28¨÷(5´Á):440-444­¶
(IF: 3.248, »â°ì±Æ¦W: 44, »â°ì´Á¥Z¼Æ: 121, »â°ì±Æ¦W: 36.36%)

IkBalpha Promoter Polymorphisms in Patients with Primary Sjögren's Syndrome
Ou TT, Lin CH, Lin YC, Li RN, Tsai WC, Liu HW, Yen JH* - - 1 - J Clin Immunol - J CLIN IMMUNOL 2008;28(5):440-444
(IF: 3.248, Journal Ranking: 44, Number of Journals of this Field: 121, Ranking: 36.36%)

45

Ãþ­·Àã©ÊÃö¸`ª¢¯f¤H¤§PD1-Ligand°ò¦]¦h§Î©Ê
¤ý²Q¬Ã, ªL¹Å¼z, §õ·ç¦~,¼ÚÀéÄË, §d¥¿´Ü, ½²¤å®i, ¼B§»¤å, ÃC¥¿½å* - - 1 - J Clin Immunol. - J CLIN IMMUNOL 2007 27¨÷(6´Á):563-7­¶
(IF: 2.886, »â°ì±Æ¦W: 53, »â°ì´Á¥Z¼Æ: 119, »â°ì±Æ¦W: 44.54%)

Polymorphisms of Genes for Programmed Cell Death 1 Ligands in Patients with Rheumatoid Arthritis
Wang SC, Lin CH, Li RN, Ou TT, Wu CC, Tsai WC, Liu HW, Yen JH* - - 1 - J Clin Immunol. - J CLIN IMMUNOL 2007;27(6):563-7
(IF: 2.886, Journal Ranking: 53, Number of Journals of this Field: 119, Ranking: 44.54%)

46

¬õ´³©Ê¯T½H¯f¤H¤§IkB alpha promoter¦h§Î©Ê
ªL¹Å¼z,¤ý²Q¬Ã,¼ÚÀéÄË,§õ·ç¦~,½²¤å®i,¼B§»¤å,ÃC¥¿½å* - - 1 - J Clin Immunol - J CLIN IMMUNOL 2007 x¨÷(x´Á):x-x­¶
(IF: 2.886, »â°ì±Æ¦W: 53, »â°ì´Á¥Z¼Æ: 119, »â°ì±Æ¦W: 44.54%)

I£eB£\ Promoter Polymorphisms in Patients with Systemic Lupus Erythematosus
Chia-Hui Lin, Shu-Chen Wang, Tsan-Teng Ou, Ruei-Nian Li, Wen-Chan Tsai, Hong-Wen Liu, Jeng-Hsien Yen* - - 1 - J Clin Immunol - J CLIN IMMUNOL 2007;x(x):x-x
(IF: 2.886, Journal Ranking: 53, Number of Journals of this Field: 119, Ranking: 44.54%)

47

­·Àã©ÊÃö¸`ª¢¯f¤HParvovirus B19¤§ ·P¬V
³¯ÅD¤É, ©P§BÁH, §õ·ç¦~, ½²¤å®i, ªL¶Q­», ½²©[Ä_, ÃC¥¿½å*, ¼B§»¤å - - 1 - JOURNAL OF RHEUMATOLOGY - J RHEUMATOL 2006 33¨÷(5´Á):887-891­¶
(IF: 2.94, »â°ì±Æ¦W: 8, »â°ì´Á¥Z¼Æ: 23, »â°ì±Æ¦W: 34.78%)

Parvovirus B19 infection in patients with rheumatoid arthritis in Taiwan
Chen YS, Chou PH, Li SN, Tsai WC, Lin KH, Tsai KB, Yen JH*, Liu HW - - 1 - JOURNAL OF RHEUMATOLOGY - J RHEUMATOL 2006;33(5):887-891
(IF: 2.94, Journal Ranking: 8, Number of Journals of this Field: 23, Ranking: 34.78%)

48

¤l®c¤º¸~½F»P¤HÃþpapillomvirus¯f¬rDNAªº©w¶qÃö«Y
½²¨q´@, §dÃè·ä, ¿à¾å¹a, §õ·ç¦~, et. al. - - 1 - Cancer Epidemiology, Biomarkers & Prevention - CANCER EPIDEM BIOMAR 2005 14¨÷(11´Á):2544-2549­¶
(IF: 4.46, »â°ì±Æ¦W: 5, »â°ì´Á¥Z¼Æ: 99, »â°ì±Æ¦W: 5.05%)

Association between quantitative high-risk human papillomavirus DNA load and cervical intraepithelial neoplasm risk
Hsiu-ting Tasi, Ching-hu Wu, Hsiao-ling Lai, Ruei-nian Li, Yi-ching Tung, Hung-yi Chuang, Trong-neng Wu, Li-jen Lin, Chi-kung Ho, Hon-wein Liu, Ming-tsang Wu - - 1 - Cancer Epidemiology, Biomarkers & Prevention - CANCER EPIDEM BIOMAR 2005;14(11):2544-2549
(IF: 4.46, Journal Ranking: 5, Number of Journals of this Field: 99, Ranking: 5.05%)

49

ªA¥Î¨Å»Ä±ìµß¤Î¤ñµá¼w¤óµß¤§Àu¹T¨Å¹ï«Õªù±ì±Û±ìµßÁc´Þ¤§¼vÅT
¤ý«a¤¸, §õ·ç¦~, ¼B´º¾±, ´^¹D¶¯, Ĭ¨|¥¿, §dµn±j, ¸â©÷©ú, ¿à«T·×, ¤ý«º¤D, ¤ý¤å©ú* - - 1 - Am J Clin Nutr - 2004 80¨÷(3´Á):737-41­¶
(IF: , »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori.
Wang KY, Li SN, Liu CS, Perng DS, Su YC, Wu DC, Jan CM, Lai CH, Wang TN, Wang WM*. - - 1 - Am J Clin Nutr - 2004;80(3):737-41
(IF: , Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

50

ªA¥Î¨Å»Ä±ìµß¤Î¤ñµá¼w¤óµß¤§Àu¹T¨Å¹ï«Õªù±ì±Û±ìµßÁc´Þ¤§¼vÅT
¤ý«a¤¸, §õ·ç¦~, ¼B´º¾±, ´^¹D¶¯, Ĭ¨|¥¿, §dµn±j, ¸â©÷©ú, ¿à«T·×, ¤ý«º¤D, ¤ý¤å©ú* - - 1 - Am J Clin Nutr - AM J CLIN NUTR 2004 80¨÷(3´Á):737-741­¶
(IF: 5.433, »â°ì±Æ¦W: 3, »â°ì´Á¥Z¼Æ: 53, »â°ì±Æ¦W: 5.66%)

Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori.
Wang KY, Li SN, Liu CS, Perng DS, Su YC, Wu DC, Jan CM, Lai CH, Wang TN, Wang WM*. - - 1 - Am J Clin Nutr - AM J CLIN NUTR 2004;80(3):737-741
(IF: 5.433, Journal Ranking: 3, Number of Journals of this Field: 53, Ranking: 5.66%)

51

¨â­Ó­P©R©Ê¤¤½u¦×ªÞ¸~¯f¨Ò : »ó³¡T/NK²Ó­M²O¤Ú½F¦X¨ÖEpstein-Barr¯f¬r·P¬V
ªô¼z¼_,¶À¬f¿«,¶À¨qà±,§õ·ç¦~,¦ó©y©Ó - - 0 - Dermatol Sinica - 2000 18¨÷(0´Á):88-94­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Nasal T/NK cell lymphoma associated with virus infection in two cases of lethal midline granuloma
Hui-Hsien Chiu, Po-Han Huang, Hsiu-Yu Huang, Shui-Nin, Li and Ji-Chen Ho - - 0 - Dermatol Sinica - 2000;18(0):88-94
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

 Project

NO
YEAR ¡X Source ¡X No ¡X Type
Project Name
Duration
1
112 ¡X M °ªÂå(ºØ¤l­pµe) ¡X KMU-M113015 ¡X  
PKC£]:¤fµÄ¤W¥ÖÅ쪬²Ó­MÀù¤¤¾AÀ³·LÀô¹Ò§ïÅܪº¥q¥O©x( )
2024/01/01 ~ 2024/12/31
2
110 ¡X M °ªÂå(ºØ¤l­pµe) ¡X KMU-M111023 ¡X  
±´°Q±M¤@©ÊDNA¥Ò°ò¤Æ½Õ±±¾÷¨î:¥HPRKCB°ò¦]©ó¤fµÄÅ窱¤W¥Ö²Ó­MÀù¤Æ¾÷¨î¬°¨Ò( )
2022/01/01 ~ 2022/12/31
3
110 ¡X NK °ªÂå-¤¤¤s¦X§@­pµe ¡X   ¡X 1 ­Ó¤H«¬
±´°Q¤GªÚ°ò²mÖL°òÃþ¤Æ¦Xª««P¶i©ó¨xÀù²Ó­M¤¤»¤¾É²Ó­Mµ{§Ç©Ê¦º¤`¤§¾÷¨î( )
2021/01/01 ~ 2021/12/31
4
109 ¡X M °ªÂå(ºØ¤l­pµe) ¡X KMU-M110009 ¡X  
±´°Q¨üDNA¥Ò°ò¤Æ½Õ±±¤§³J¥Õ¿E酶C£]¹ï¤fµÄÀù²Ó­MÀù¤Æªº¼vÅT( )
2021/01/01 ~ 2021/12/31
5
109 ¡X NK °ªÂå-¤¤¤s¦X§@­pµe ¡X NSYSUKMU109-I002-1 ¡X 2 ¾ã¦X«¬
¤ÀÂ÷³n¬À·ä»P®üºø®ü¬v¤ÑµMª«»P¦X¦¨¬ÛÃö­l¥Íª«( )
2020/01/01 ~ 2020/12/31
6
109 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X MOST110-2813-C-037-021-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
110¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-§õÌÉ¿Ù(¥Íª«3)( )
2021/07/01 ~ 2022/02/28
7
109 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X MOST110-2813-C-037-022-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
110¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-¦¿©w¯§(¥Íª«2)( )
2021/07/01 ~ 2022/02/28
8
105 ¡X M °ªÂå(ºØ¤l­pµe) ¡X KMU-M106036 ¡X  
±´°QRAR£]©MCDH1°ò¦]¥Ò°ò¤Æ»P¤fµÄÀù²Ó­M¾E²¾¯à¤Oªº¬ÛÃö¾÷¨î( )
2017/01/01 ~ 2017/12/31
9
104 ¡X TP ³»¦y­pµe(°ªÂå) ¡X KMU-TP104E28 ¡X  
¤l­pµe¤G¤Q¤K¡B±´°Q°ò¦]¥Ò°ò¤Æ»P¤fµÄÀù²Ó­M¾E²¾ªº¬ÛÃö¾÷¨î( )
2015/10/01 ~ 2016/09/30
10
103 ¡X M °ªÂå(ºØ¤l­pµe) ¡X KMU-M104013 ¡X  
±´°QRAR£]2½Õ±±FOXA2°ò¦]¥Ò°ò¤Æ»P¤J«I©Ê­¹¹DÅ쪬²Ó­MÀùªº¬ÛÃö©Ê( )
2015/01/01 ~ 2015/12/31
11
102 ¡X M °ªÂå(ºØ¤l­pµe) ¡X KMU-M103016 ¡X  
±´°QRAR£]2°ò¦]¥Ò°ò¤Æ»P¤J«I©Ê­¹¹DÅ쪬²Ó­MÀùªº¬ÛÃö©Ê( )
2014/01/01 ~ 2014/12/31
12
094 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X NSC95-2815-C-037-006-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
¤j±M´»´Á­pµe--ÄÁ¯Â¬À( )
2006/07/01 ~ 2007/02/28
13
088 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC 89-2320-B-037-012- ¡X 1 ­Ó¤H«¬
EB¯f¬r²Ä¤@«¬¼ç¥ñ©Ê½¤³J¥Õ¹ï²Ó­MÂà§Î¤§¬ã¨s(Study of latent membrane proteinl of Epstein-Barr virus in transformed Balb/c 3T3 cell)
1999/08/01 ~ 2000/07/31
14
087 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC88-2314-B-037-099- ¡X 1 ­Ó¤H«¬
EB¯f¬r¦­´Á°ò¦]BSLF1±Ò°Ê¤l¤§¬ã¨s(Study of the promoter of an early gene BSLF in Epstein-Barr virus)
1998/08/01 ~ 1999/07/31

 Patent