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 Education

School — Major — Degree Duration

高雄醫學大學 — 醫學研究所(畢) — 博士

Doctorate, Graduate Institute of Medicine, Kaohsiung Medical University

 1997/09 — 2006/06

高雄醫學院 — 生物化學研究所(畢) — 碩士

Master, Graduate Institute of Biochemistry, Kaohsiung Medical University (former Kaohsiung Medical College)

 1995/09 — 1997/06

東海大學 — 生物學系(畢) — 學士

Bachelor, Department of Biology, Tunghai University

 1982/09 — 1986/06

 Intramural Experience

Office/Department/Institute Position Duration
生物醫學暨環境生物學系 Department of Biomedical Science and Environmental Biology   Associate Professor 2014/08/01 —  
生物醫學暨環境生物學系 Department of Biomedical Science and Environmental Biology   Assistant Professor 2006/08/01 — 2014/07/31
生物醫學暨環境生物學系 Department of Biomedical Science and Environmental Biology   Lecturer 2003/08/01 — 2006/07/31
生物學系 Department of Biology   Lecturer 1997/08/01 — 2003/07/31
生物學系 Department of Biology   Teaching Assistant 1990/08/01 — 1997/07/31

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 生物學之生化及分子生物 Biochemistry and Molecular Biology
2 生物醫農類 Biology, Medicine and Agriculture 醫學之生化及分子生物 Medical Biochemistry and Molecular Biology

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

建立細胞及動物模式之生物相關領域

 

 Area(s) of Expertise & Research

生物醫學,分子生物學,生物化學,細胞生物學,

molecular and cell biology, biochemistry

 Publication

NO Publication
1

The Controversial Roles of Areca Nut: Medicine or Toxin
劉佩芬, 張永福* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 24卷(10期):8996頁
(IF: 5.6, 領域排名: 66, 領域期刊數: 285, 領域排名: 23.16%)

The Controversial Roles of Areca Nut: Medicine or Toxin
Pei-Feng Liu, Yung-Fu Chang* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023;24(10):8996
(IF: 5.6, Journal Ranking: 66, Number of Journals of this Field: 285, Ranking: 23.16%)
2

TMEM211 Promotes Tumor Progression and Metastasis in Colon Cancer
張永福, 王興翔#, 徐志文, Wei-Lun Tsai, Cheng-Hsin Lee, Chun-Lin Chen, 劉佩芬* - - 1 - CURRENT ISSUES IN MOLECULAR BIOLOGY - CURRENT ISSUES IN MOLECULAR BIOLOGY 2023 45卷(6期):4529-4543頁
(IF: 3.1, 領域排名: 173, 領域期刊數: 285, 領域排名: 60.70%)

TMEM211 Promotes Tumor Progression and Metastasis in Colon Cancer
Yung-Fu Chang, Hsing-Hsang Wang#, Chih-Wen Shu , Wei-Lun Tsai , Cheng-Hsin Lee, Chun-Lin Chen, Pei-Feng Liu* - - 1 - CURRENT ISSUES IN MOLECULAR BIOLOGY - CURRENT ISSUES IN MOLECULAR BIOLOGY 2023;45(6):4529-4543
(IF: 3.1, Journal Ranking: 173, Number of Journals of this Field: 285, Ranking: 60.70%)
3

N-acetyl cysteine prevents arecoline-inhibited C2C12 myoblast differentiation through ERK1/2 phosphorylation
李怡萱, 蕭俊鴻, 張永福* - - 1 - PLoS One - PLOS ONE 2022 17卷(7期):e0272231頁
(IF: 3.752, 領域排名: 29, 領域期刊數: 73, 領域排名: 39.73%)

N-acetyl cysteine prevents arecoline-inhibited C2C12 myoblast differentiation through ERK1/2 phosphorylation
Yi-Xuan Li , Chun-Hung Hsiao , Yung-Fu Chang* - - 1 - PLoS One - PLOS ONE 2022;17(7):e0272231
(IF: 3.752, Journal Ranking: 29, Number of Journals of this Field: 73, Ranking: 39.73%)
4

Effects of areca nut consumption on cell differentiation of osteoblasts, myoblasts, and fibroblasts
張永福* - - 1 - BIOCELL - BIOCELL 2022 47卷(2期):283-287頁
(IF: 1.11, 領域排名: 79, 領域期刊數: 94, 領域排名: 84.04%)

Effects of areca nut consumption on cell differentiation of osteoblasts, myoblasts, and fibroblasts
Yung-Fu Chang* - - 1 - BIOCELL - BIOCELL 2022;47(2):283-287
(IF: 1.11, Journal Ranking: 79, Number of Journals of this Field: 94, Ranking: 84.04%)
5

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice
劉鼎元, 陳郁佳, 鐘育志, Huai-Jen Tsai, Chien-Chin Lee, Ya-Sian Chang, 張建國*,張永福* - - 1 - Open Biology - Open Biol 2017 7卷(1期):160303頁
(IF: 4.822, 領域排名: 98, 領域期刊數: 290, 領域排名: 33.79%)

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice
Ting-Yuan Liu, Yu-Chia Chen, Yuh-Jyh Jong, Huai-Jen Tsai, Chien-Chin Lee, Ya-Sian Chang, Jan-Gowth Chang*,Yung-Fu Chang* - - 1 - Open Biology - Open Biol 2017;7(1):160303
(IF: 4.822, Journal Ranking: 98, Number of Journals of this Field: 290, Ranking: 33.79%)
6

Brefeldin A effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells
曾昭能, Chien-Fu Huang, 卓忠隆, 張學偉, Chao-Wei Huang, 邱建智*, 張永福* - - 1 - Molecules - MOLECULES 2013 18卷(9期):10242-10253頁
(IF: 2.428, 領域排名: 24, 領域期刊數: 57, 領域排名: 42.11%)

Brefeldin A effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells
Chao-Neng Tseng, Chien-Fu Huang, Chung-Lung Cho, Hsueh-Wei Chang, Chao-Wei Huang, Chien-Chih Chiu*, Yung-Fu Chang* - - 1 - Molecules - MOLECULES 2013;18(9):10242-10253
(IF: 2.428, Journal Ranking: 24, Number of Journals of this Field: 57, Ranking: 42.11%)
7

Arecoline inhibits and destabilizes agrin-induced acetylcholine receptor cluster formation in C2C12 myotubes
張永福*, 劉鼎元, 劉紹東 - - 1 - Food and Chemical Toxicology - FOOD CHEM TOXICOL 2013 60卷(1期):391–396頁
(IF: 2.602, 領域排名: 16, 領域期刊數: 126, 領域排名: 12.70%)

Arecoline inhibits and destabilizes agrin-induced acetylcholine receptor cluster formation in C2C12 myotubes
Yung-Fu Chang*, Ting-Yuan Liu, Shao-Tung Liu - - 1 - Food and Chemical Toxicology - FOOD CHEM TOXICOL 2013;60(1):391–396
(IF: 2.602, Journal Ranking: 16, Number of Journals of this Field: 126, Ranking: 12.70%)
8

Brefeldin A Inhibits Cancer Stem Cell Properties in Human Lung Cancer Cells
曾昭能, 卓忠隆, Tzan-Wen Chen, 邱建智, 張學偉, 張芳榮*, 張永福* - - 1 - Current Signal Transduction Therapy - Curr. Signal Transduct. Ther. 2013 8卷(2期):113-118頁
(IF: 0.446, 領域排名: 236, 領域期刊數: 260, 領域排名: 90.77%)

Brefeldin A Inhibits Cancer Stem Cell Properties in Human Lung Cancer Cells
Chao-Neng Tseng, Chung-Lung Cho, Tzan-Wen Chen, Chien-Chih Chiu, Hsueh-Wei Chang, Fang-Rong Chang,*, Yung-Fu Chang* - - 1 - Current Signal Transduction Therapy - Curr. Signal Transduct. Ther. 2013;8(2):113-118
(IF: 0.446, Journal Ranking: 236, Number of Journals of this Field: 260, Ranking: 90.77%)
9

Arecoline inhibits myogenic differentiation of C2C12 myoblasts by reducing STAT3 phosphorylation
張永福, 劉鼎元, 劉紹東, 曾昭能* - - 1 - Food and Chemical Toxicology - FOOD CHEM TOXICOL 2012 50卷(10期):3433–3439頁
(IF: 2.602, 領域排名: 16, 領域期刊數: 126, 領域排名: 12.70%)

Arecoline inhibits myogenic differentiation of C2C12 myoblasts by reducing STAT3 phosphorylation
Yung-Fu Chang, Ting-Yuan Liu, Shao-Tung Liu, and Chao-Neng Tseng* - - 1 - Food and Chemical Toxicology - FOOD CHEM TOXICOL 2012;50(10):3433–3439
(IF: 2.602, Journal Ranking: 16, Number of Journals of this Field: 126, Ranking: 12.70%)
10

Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes
張永福, Hui-Ju Chou, Ying-Cheng Yen,張學偉,洪義人, Hurng-Wern Huang*,曾昭能* - - 1 - FEBS Lett - FEBS LETT 2012 586卷(19期):3111-6頁
(IF: 3.601, 領域排名: 24, 領域期刊數: 73, 領域排名: 32.88%)

Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes
Yung-Fu Chang, Hui-Ju Chou, Ying-Cheng Yen, Hsueh-Wei Chang, Yi-Ren Hong, Hurng-Wern Huang*, Chao-Neng Tseng* - - 1 - FEBS Lett - FEBS LETT 2012;586(19):3111-6
(IF: 3.601, Journal Ranking: 24, Number of Journals of this Field: 73, Ranking: 32.88%)
11

A preliminary report on the toxicity of arecoline on early pregnancy in mice.
劉紹東, 楊高奇, 李怡琛, 張永福* - - 1 - Food and Chemical Toxicology - FOOD CHEM TOXICOL 2011 49卷(1期):144-148頁
(IF: 2.602, 領域排名: 16, 領域期刊數: 126, 領域排名: 12.70%)

A preliminary report on the toxicity of arecoline on early pregnancy in mice.
Liu ST, Young GC, Lee YC, Chang YF* - - 1 - Food and Chemical Toxicology - FOOD CHEM TOXICOL 2011;49(1):144-148
(IF: 2.602, Journal Ranking: 16, Number of Journals of this Field: 126, Ranking: 12.70%)
12

過氧化氫降低被穩定減弱SMN蛋白質的HeLa細胞的存活率
劉鼎元, 游仲逸, 高振興, 曾昭能, 鐘育志, 張建國, 吳秀梅, 張永福* - - 1 - Kaohsiung Journal of Medical Sciences - KAOHSIUNG J MED SCI 2011 27卷(3期):102-107頁
(IF: 0.474, 領域排名: 92, 領域期刊數: 106, 領域排名: 86.79%)

Hydrogen peroxide decreases the survival rate of HeLa cells with stable knockdown of survival motor neuron protein
Ting-Yuan Liu, Chung-Yee Yuo, Cheng-Hsing Kao, Chao-Neng Tseng , Yuh-Jyh Jong, Jan-Gowth Chang, Shou-Mei Wu, Yung-Fu Chang* - - 1 - Kaohsiung Journal of Medical Sciences - KAOHSIUNG J MED SCI 2011;27(3):102-107
(IF: 0.474, Journal Ranking: 92, Number of Journals of this Field: 106, Ranking: 86.79%)
13

Inhibition of the Epstein-Barr virus lytic cycle by moronic acid
張芳榮, 謝宜君, 張永福, Lee KH, Wu YC, Chang LK* - - 1 - Antiviral Res. - ANTIVIR RES 2010 85卷(3期):490-495頁
(IF: 4.439, 領域排名: 34, 領域期刊數: 249, 領域排名: 13.65%)

Inhibition of the Epstein-Barr virus lytic cycle by moronic acid
Chang FR, Hsieh YC, Chang YF, Lee KH, Wu YC, Chang LK* - - 1 - Antiviral Res. - ANTIVIR RES 2010;85(3):490-495
(IF: 4.439, Journal Ranking: 34, Number of Journals of this Field: 249, Ranking: 13.65%)
14

hydroxyurea對脊髓性肌肉性萎縮症病人及細胞之影響
梁文貞,游仲逸,張建國,陳怡靜,張永福,王慧儀,朱芸慧,邱世欣,鐘育志* - - 1 - J NEUROL SCI - J NEUROL SCI 2008 24卷(1-2期):87-94頁
(IF: 2.359, 領域排名: 68, 領域期刊數: 156, 領域排名: 43.59%)

The effect of hydroxyurea in spinal muscular atrophy cells and patients.
Liang WC, Yuo CY, Chang JG, Chen YC, Chang YF, Wang HY, Ju YH, Chiou SS, Jong YJ* - - 1 - J NEUROL SCI - J NEUROL SCI 2008;24(1-2):87-94
(IF: 2.359, Journal Ranking: 68, Number of Journals of this Field: 156, Ranking: 43.59%)
15

利用毛細管電泳定量SMN1和SMN2用於診斷脊髓肌肉萎縮症
王俊棋, 張建國, Jerome Ferrance, 陳心怡, 游仲逸, 張永福, 鍾育志*, 吳秀梅*, 葉昭宏 - - 1 - Electrophoresis - ELECTROPHORESIS 2008 29卷(13期):2904-2911頁
(IF: 3.509, 領域排名: 7, 領域期刊數: 70, 領域排名: 10.00%)

Quantification of SMN1 and SMN2 genes by capillary electrophoresis for diagnosis of spinal muscular atrophy
Chun-Chi Wang, Jan-Gowth Chang, Jerome Ferrance, Hsin-Yi Chen, Chung-Yee You, Yung-Fu Chang, Yuh-Jyh Jong*, Shou-Mei Wu*, Chao-Hung Yeh - - 1 - Electrophoresis - ELECTROPHORESIS 2008;29(13):2904-2911
(IF: 3.509, Journal Ranking: 7, Number of Journals of this Field: 70, Ranking: 10.00%)
16

無
李彥賢, 鄭智美, 張永福, 王婷儀, 游仲逸* - - 1 - Biochem. Biophys. Res. Commun. - BIOCHEM BIOPH RES CO 2007 354卷(0期):391-395頁
(IF: 2.749, 領域排名: 27, 領域期刊數: 69, 領域排名: 39.13%)

Apoptin T108 phosphorylation is not required for its tumor-specific nuclear localization but partially affects its apoptotic activity
Yen-Hsien Lee, Chih-Mei Cheng, Yung-Fu Chang, Ting-Yi Wang, Chung-Yee Yuo* - - 1 - Biochem. Biophys. Res. Commun. - BIOCHEM BIOPH RES CO 2007;354(0):391-395
(IF: 2.749, Journal Ranking: 27, Number of Journals of this Field: 69, Ranking: 39.13%)
17

The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination
張永福, 鄭智美, 張麗冠, 鐘育志, 游仲逸* - - 1 - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS - BIOCHEM BIOPH RES CO 2006 342卷(4期):1022-1026頁
(IF: 2.855, 領域排名: 24, 領域期刊數: 66, 領域排名: 36.36%)

The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination
Chang YF, Cheng CM, Chang LK, Jong YJ, Yuo CY - - 1 - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS - BIOCHEM BIOPH RES CO 2006;342(4):1022-1026
(IF: 2.855, Journal Ranking: 24, Number of Journals of this Field: 66, Ranking: 36.36%)
18

cIAP1結合蛋白質及cIAP1泛素化之研究
張永福 - - 0 - 高雄醫學大學醫學研究所博士論文 - 2005 0卷(0期):1-105頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

The studies on the cIAP1-associated proteins and cIAP1 ubiquitination
Yung-Fu Chang - - 0 - 高雄醫學大學醫學研究所博士論文 - 2005;0(0):1-105
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)
19

病毒凋亡蛋白Apoptin和細胞內Hippi蛋白的結合作用
鄭智美, 黃小萍, 張永福, 鍾文苑, 游仲逸* - - 1 - Biochem. Biophys. Res. Commun. - BIOCHEM BIOPH RES CO 2003 305卷(2期):359-364頁
(IF: 3, 領域排名: 97, 領域期刊數: 261, 領域排名: 37.16%)

The viral death protein Apoptin interacts with Hippi, the protein interactor of Huntingtin interacting protein 1
Chih-Mei Cheng, Shiao-ping Huang, Yung-Fu Chang, Wen-Yuan Chung, Chung-Yee Yuo* - - 1 - Biochem. Biophys. Res. Commun. - BIOCHEM BIOPH RES CO 2003;305(2):359-364
(IF: 3, Journal Ranking: 97, Number of Journals of this Field: 261, Ranking: 37.16%)
20

無
張永福,Jiao Wei,1 Xiaoli Liu, 陳彥旭, Matthew D. Layne, and Shaw-Fang Yet - - 1 - Am J Physiol Heart Circ Physiol - AM J PHYSIOL-HEART C 2003 285卷(4期):H1675-1683頁
(IF: 3.658, 領域排名: 8, 領域期刊數: 70, 領域排名: 11.43%)

Identification of a CArG-independent region of the cysteine-rich protein 2 promoter that directs expression in the developing vasculature
Yung-Fu Chang,Jiao Wei,1 Xiaoli Liu, Yen-Hsu Chen, Matthew D. Layne, and Shaw-Fang Yet - - 1 - Am J Physiol Heart Circ Physiol - AM J PHYSIOL-HEART C 2003;285(4):H1675-1683
(IF: 3.658, Journal Ranking: 8, Number of Journals of this Field: 70, Ranking: 11.43%)
21

Sequence of a Human E2F-4 Pseudogene with Shortened AGC Trinucleotide Repeats
鄭智美,張永福,游仲逸 - - 0 - The Kaohsiung Journal of Medical Sciences - 1997 0卷(13期):448-425頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

待補
待補 - - 0 - The Kaohsiung Journal of Medical Sciences - 1997;0(13):448-425
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

 Project

NO
YEAR — Source — No — Type
Project Name
 Duration
1
112 — M 高醫(種子計畫) — KMU-M113025 —  
化學合成物質對神經纖維延長之研究( )
 2024/01/01 ~ 2024/12/31
2
108 — N 國科會(原科技部) — MOST108-2314-B-037-075 — 1 個人型
檳榔鹼對骨母細胞分化影響之研究( )
 2019/08/01 ~ 2020/07/31
3
104 — TP 頂尖計畫(高醫) — KMU-TP104PR16 —  
以蛋白質體學方法篩選淋巴結中調節癌細胞轉移之分子( )
 2016/02/04 ~ 2016/09/30
4
103 — M 高醫(種子計畫) — KMU-M104003 —  
檳榔鹼對肌肉發育機制及類成骨細胞分化影響之研究( )
 2015/01/01 ~ 2015/12/31
5
102 — M 高醫(種子計畫) — KMU-M103001 —  
篩選脊髓肌肉萎縮症(SMA)的運動神元經纖維增長之藥物( )
 2014/01/01 ~ 2014/12/31
6
101 — M 高醫(種子計畫) — KMU-M102002 —  
檳榔鹼對肌肉發育及成骨細胞分化影響之研究( )
 2012/12/01 ~ 2013/12/31
7
098 — N 國科會(原科技部) — NSC96-2314-B-037-035-MY3 — 2 整合型
脊髓肌肉萎縮症:從生物標記到治療對策-以基因剔除及RNA干擾方法研究hnRNP A1和SPRK2對SMN缺陷之影響(3/3)( )
 2009/08/01 ~ 2010/07/31
8
097 — N 國科會(原科技部) — NSC96-2314-B-037-035-MY3 — 2 整合型
脊髓肌肉萎縮症:從生物標記到治療對策-以基因剔除及RNA干擾方法研究hnRNP A1和SPRK2對SMN缺陷之影響(2/3)( )
 2008/08/01 ~ 2010/07/31
9
096 — N 國科會(原科技部) — NSC96-2314-B-037-035-MY3 — 2 整合型
脊髓肌肉萎縮症:從生物標記到治療對策-以基因剔除及RNA干擾方法研究hnRNP A1和SPRK2對SMN缺陷之影響(1/3)( )
 2007/08/01 ~ 2010/07/31
10
088 — M 高醫(種子計畫) — KMC89-A-03 —  
人類乳癌細胞株MCF7中與果蠅細胞凋亡蛋白質REAPER結的蛋白質之基因選殖( )
 1999/08/01 ~ 1999/07/31
11
087 — M 高醫(種子計畫) — KMC88-A-07 —  
選殖與果蠅細胞凋亡蛋白質REAPER結合之人類基因( )
 1998/11/15 ~ 1999/07/31

 Patent

NO Patent Name Country Certified Date Patent No
1 hnRNP A1 基因剔除之動物模式及其用途 美國 2015/02/03 8,946,503