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 Education

School ¡X Major ¡X Degree Duration

°ª¶¯Âå¾Ç°| ¡X Âå¾Ç¬ã¨s©Ò(²¦) ¡X ³Õ¤h

Doctorate, Graduate Institute of Medicine, Kaohsiung Medical College

1989/09 ¡X 1994/06

°ª¶¯Âå¾Ç°| ¡X Âå¾Ç¬ã¨s©Ò(²¦) ¡X ºÓ¤h

Master, Graduate Institute of Medicine, Kaohsiung Medical College

1987/09 ¡X 1989/06

°ª¶¯Âå¾Ç°| ¡X ÃľǨt(²¦) ¡X ¾Ç¤h

Bachelor, School of Pharmacy, Kaohsiung Medical College

1983/09 ¡X 1987/06

 Intramural Experience

Office/Department/Institute Position Duration
±Ð°È³B Office of Academic Affairs   Associate Vice President for Academic Affairs 2024/08/01 ¡X 2025/07/31
¤ÑµMÃĪ«¬ã¨s©Ò Graduate Institute of Natural Products   Professor 2009/08/01 ¡X 2009/08/01
ÃIJz¾Ç¬ì Department of Pharmacology   Professor 2009/08/01 ¡X  
ÃIJz¾Ç¬ì Department of Pharmacology   Professor 2007/08/01 ¡X 2009/07/31
ÃIJz¾Ç¬ã¨s©Ò Graduate Institute of Pharmacology   Associate Professor 2005/11/24 ¡X 2005/07/31
ÃIJz¾Ç¬ã¨s©Ò Graduate Institute of Pharmacology   Professor 2005/08/01 ¡X 2007/07/31
ÃIJz¾Ç Pharmacology   Associate Professor 1998/08/01 ¡X 2005/11/23
ÃIJz¾Ç Pharmacology   Lecturer 1989/08/01 ¡X 1998/07/31

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 ¥Íª«Âå¹AÃþ Biology, Medicine and Agriculture ÃIJz¤Î¬r²z Pharmacology and Toxicology
2 ¥Íª«Âå¹AÃþ Biology, Medicine and Agriculture ÃľǤΤ¤ÂåÃÄ Pharmacy and Chinese Medicine and Pharmacy

 Research & Technology Platform Open to the Outside

Myocardial ischemia-reperfusion animal and cell models

 Interested Area(s)for Interdisciplinary Research

¤ßŦ¦åºÞ¯e¯f¤Î¨äÃĪ«¬ãµo¡Bµ°ª¬°Ê¯ßµw¤Æ¤§¾÷Âà¤Î¨äÃĪ«¬ãµo¡B§Üµoª¢ÃĪ«¤Î¨ä¾÷Âà±´°Q

Cardiovascular pharmacology; Inflammation and bone pharmacology; Drug development in myocardial ischemia-reperfusion, atherosclerosis and restenosis; Traditional Chinese (Herbal) Medicine

 Area(s) of Expertise & Research

¤ßŦ¦åºÞÃIJz¾Ç¡B¤ßŦ¯Ê¦å¯Ê®ñ¬ã¨s¡B§Ü¦åºÞ¼W¥Í¡B¦åºÞ½F¬ã¨s¡B§Ü°©ÃPÃĪ«¬ã¨s¡B¤¤¯óÃÄÃIJz¬ã¨s¡B¤ß¦Ù±ð¶ë»P¤ß¦ÙªÎ«p¤§ÃĪ«¬ãµo¡BªvÀøµ°ª¬°Ê¯ßµw¤Æ»P¦åºÞ½F¤§ÃĪ«¬ãµo¡B§Ü¦åºÞ²Ó­M¼W¥ÍÃĪ«¤§¬ã¨s ªvÀø¤ßŦ¦åºÞ¯e¯f¤§¤¤¯óÃĪ«¬ã¨s ¼vÅT°©Àf¤§ÃĪ«¬ãµo

Cardiovascular pharmacology Drug development in atherosclerosis and restenosis Drug development in myocardial ischemia-reperfusion Inflammation and bone pharmacology

 Publication

NO Publication
1

¯ùÆP­l¥Íª«KMUP-3³z¹LPI3K/Akt/eNOS¼W±j¦Û¾½§@¥ÎÀu¤Æ¤ß¦Ù²Ó­M«OÅ@
¶À¤W®¦, ®}¥ò»¨, ¿½¬f¤å, ¼B©É¼y, §d¬±¨k, À¹¥ô®¥, ¼B¤¤¥­*, ¸­¦Ë¨Ó* - - 1 - BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY - BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 2024 134¨÷(6´Á):818-832­¶
(IF: 3.1, »â°ì±Æ¦W: 46, »â°ì´Á¥Z¼Æ: 94, »â°ì±Æ¦W: 48.94%)

Optimizing myocardial cell protection with xanthine derivative KMUP-3 potentiates autophagy through the PI3K/Akt/eNOS axis.
Shang-En Huang, Jong-Hau Hsu, Bo-Wen Shiau, Yi-Ching Liu, Bin-Nan Wu, Zen-Kong Dai, Chung-Pin Liu, Jwu-Lai Yeh - - 1 - BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY - BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 2024;134(6):818-832
(IF: 3.1, Journal Ranking: 46, Number of Journals of this Field: 94, Ranking: 48.94%)

2

³J¥Õ酶Åé§í¨î¾¯bortezomibªý¤îªÍ°Ê¯ß¥­·Æ¦Ù²Ó­Mªº¼W¥Í©M¾E²¾
¼B©É¼y, ´¿¦Ð¨¯, Ãö«B¤ß, ¤ýÅï¿P, ¶À¤W®¦, ½²¾åµÓ, ¸­¦Ë¨Ó*, ®}¥ò»¨* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2024 40¨÷(6´Á):542-552­¶
(IF: 3.3, »â°ì±Æ¦W: 81, »â°ì´Á¥Z¼Æ: 136, »â°ì±Æ¦W: 59.56%)

Proteasome inhibitor bortezomib prevents proliferation and migration of pulmonary arterial smooth muscle cells
Yi-Ching Liu, Yu-Hsin Tseng, Yu-Hsin Kuan, Lin-Yen Wang, Shang-En Huang, Siao-Ping Tsai, Jwu-Lai Yeh, Jong-Hau HsuYi-Ching Liu, Yu-Hsin Tseng, Yu-Hsin Kuan, Lin-Yen Wang, Shang-En Huang, Siao-Ping Tsai, Jwu-Lai Yeh, Jong-Hau Hsu - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2024;40(6):542-552
(IF: 3.3, Journal Ranking: 81, Number of Journals of this Field: 136, Ranking: 59.56%)

3

¶ÀáIËï­l¥Íª« KMUP-1 §í¨î§C®ñ»¤¾É TRPC1 ªí²{¤Î¶t¦À½Õ±±¶tÂ÷¤l¬y¦bªÍ°Ê¯ß¦åºÞ¥­·Æ¦Ù²Ó­M
À¹¥ô®¥, Yi-Chen Chen, Á¯À¬Â, ¸­¦Ë¨Ó, ®}¥ò»¨, §d¬±¨k* - - 1 - PHARMACEUTICALS (BASEL, SWITZERLAND) - PHARMACEUTICALS 2024 17¨÷(4´Á):440­¶
(IF: 4.6, »â°ì±Æ¦W: 71, »â°ì´Á¥Z¼Æ: 278, »â°ì±Æ¦W: 25.54%)

The Xanthine Derivative KMUP-1 Inhibits Hypoxia-Induced TRPC1 Expression and Store-Operated Ca Entry in Pulmonary Arterial Smooth Muscle Cells.
Zen-Kong Dai, Yi-Chen Chen, Su-Ling Hsieh, Jwu-Lai Yeh, Jong-Hau Hsu, Bin-Nan Wu - - 1 - PHARMACEUTICALS (BASEL, SWITZERLAND) - PHARMACEUTICALS 2024;17(4):440
(IF: 4.6, Journal Ranking: 71, Number of Journals of this Field: 278, Ranking: 25.54%)

4

¸¯®Ú¯À¦b°±¸g«á¤ßŦ«OÅ@¤¤ªº§Üª¢©M§Ü®ñ¤Æ§@¥Î¡GAkt ©M¦å¬õ¯À¥[®ñ酶-1 ªº¨¤¦â
ÃC¨Ø«º, ¶À¤W®¦#, ®}¥ò»¨, ³¢©Óµ¾, »¯¥É­^, ¤ý¶©ºÓ*, ¸­¦Ë¨Ó* - - 1 - THE AMERICAN JOURNAL OF CHINESE MEDICINE - AMERICAN JOURNAL OF CHINESE MEDICINE 2023 51¨÷(1´Á):149-168­¶
(IF: 5.7, »â°ì±Æ¦W: 3, »â°ì´Á¥Z¼Æ: 28, »â°ì±Æ¦W: 10.71%)

Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-1.
Pei-Tzu Yen, Shang-En Huang#, Jong-Hau Hsu, Cheng-Hsiang Kuo, Yu-Ying Chao, Lung-Shuo Wang*, Jwu-Lai Yeh* - - 1 - THE AMERICAN JOURNAL OF CHINESE MEDICINE - AMERICAN JOURNAL OF CHINESE MEDICINE 2023;51(1):149-168
(IF: 5.7, Journal Ranking: 3, Number of Journals of this Field: 28, Ranking: 10.71%)

5

Autologous Fat Grafting in Female Genital Area Improves Sexual Function by Increasing Collagenesis, Angiogenesis, and Estrogen Receptors.
¿à¶®Á¨,§dª@¾ì,©PªÃèû, Che Lin,¸­¦Ë¨Ó,ªL¤~¥Á,½²§Ó¤¯,Á©sÁ¾,¶À®ÑÂE - - 1 - AESTHETIC SURGERY JOURNAL - AESTHETIC SURGERY JOURNAL 2023 2023 Feb¨÷(28´Á):sjad040­¶
(IF: 4.485, »â°ì±Æ¦W: 35, »â°ì´Á¥Z¼Æ: 213, »â°ì±Æ¦W: 16.43%)

Autologous Fat Grafting in Female Genital Area Improves Sexual Function by Increasing Collagenesis, Angiogenesis, and Estrogen Receptors.
Ya-Wei Lai, Sheng-Hua Wu, Ping-Ruey Chou, Che Lin, Jwu-Lai Yeh, Tsai-Ming Lin, Chee-Yin Chai, Meng-Chien Willie Hsieh, Shu-Hung Huang - - 1 - AESTHETIC SURGERY JOURNAL - AESTHETIC SURGERY JOURNAL 2023;2023 Feb(28):sjad040
(IF: 4.485, Journal Ranking: 35, Number of Journals of this Field: 213, Ranking: 16.43%)

6

¶ÀáIËï­l¥Íª« KMUP-1 ¥i§ïµ½µøºô½¤¯fÅÜ
¸­¦Ë¨Ó, ³¢©Óµ¾, ¬I³Õ¤å, ®}¥ò»¨, ¼ï©ÉºÂ, ¶À«³³Ô* - - 1 - BIOMEDICINE & PHARMACOTHERAPY = BIOMEDECINE & PHARMACOTHERAPIE - BIOMEDICINE & PHARMACOTHERAPY 2023 165¨÷(-´Á):115109­¶
(IF: 7.5, »â°ì±Æ¦W: 23, »â°ì´Á¥Z¼Æ: 277, »â°ì±Æ¦W: 8.30%)

Xanthine derivative KMUP-1 ameliorates retinopathy.
Jwu-Lai Yeh, Cheng-Hsiang Kuo, Po-Wen Shih, Jong-Hau Hsu, Peng I-Chen, Yi-Hsun Huang* - - 1 - BIOMEDICINE & PHARMACOTHERAPY = BIOMEDECINE & PHARMACOTHERAPIE - BIOMEDICINE & PHARMACOTHERAPY 2023;165(-):115109
(IF: 7.5, Journal Ranking: 23, Number of Journals of this Field: 277, Ranking: 8.30%)

7

¥i·»©Ê CD93 ¾®¶°¯À¼Ëµ²ºc°ì¹jÂ÷ HMGB1 ¥H§ïµ½ª¢¯g©Ê¯e¯f
¶À¤W®¦, ³¢©Óµ¾, ¿½ÔT§E, ¨H®a·ç, §õªÚ«º, ±iºÑ­^, ®}¥ò»¨, §dµØªL, ¸­¦Ë¨Ó*, ¿à¬L¿«* - - 1 - THERANOSTICS - THERANOSTICS 2023 13¨÷(12´Á):4059-4078­¶
(IF: 12.4, »â°ì±Æ¦W: 8, »â°ì´Á¥Z¼Æ: 136, »â°ì±Æ¦W: 5.88%)

Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases
Huang SE, Kuo CH, Shiao SY, Shen CR, Lee FT, Chang BI, Hsu JH, Wu HL, Yeh JL*, Lai CH* - - 1 - THERANOSTICS - THERANOSTICS 2023;13(12):4059-4078
(IF: 12.4, Journal Ranking: 8, Number of Journals of this Field: 136, Ranking: 5.88%)

8

¶ÀÍÁ¯À³z¹L§í¨îµoª¢©M®ñ¤ÆÀ£¤O¹ï¦åºÞºò±i¯À II ª`¤Jªº¸¡¥D°Ê¯ß½F¨ã¦³¦åºÞ«OÅ@§@¥Î
Erna Sulistyowati, ¶À¤W®¦, ¾GÚzÀM, »¯¥É­^, §õ¨Î¶§, ±i瀞¤å, ªL©s¸©, ªL©ú©¾*, ¸­¦Ë¨Ó* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 24¨÷(21´Á):16004­¶
(IF: 5.6, »â°ì±Æ¦W: 66, »â°ì´Á¥Z¼Æ: 285, »â°ì±Æ¦W: 23.16%)

Vasculoprotective Potential of Baicalein in Angiotensin II-Infused Abdominal Aortic Aneurysms through Inhibiting Inflammation and Oxidative Stress
Erna Sulistyowati, Shang-En Huang, Tsung-Lin Cheng, Yu-Ying Chao, Chia-Yang Li, Ching-Wen Chang, Meng-Xuan Lin, Ming-Chung Lin*, Jwu-Lai Yeh* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023;24(21):16004
(IF: 5.6, Journal Ranking: 66, Number of Journals of this Field: 285, Ranking: 23.16%)

9

YULINK¦bªÍ°Ê¯ß¥­·Æ¦Ù²Ó­M¾E²¾¡B¼W¥Í©M¿}¸Ñ§@¥Î¤¤ªº·s§@¥Î¡G¹ïªÍ°Ê¯ß°ªÀ£ªº¼vÅT
§d¯q¹Å*, Wang WT, Yang MC, Su YT,¸­¦Ë¨Ó,®}¥ò»¨,§d«T¤¯# - - 1 - Biological Research - BIOLOGICAL RESEARCH 2023 56¨÷(1´Á):66­¶
(IF: 6.7, »â°ì±Æ¦W: 9, »â°ì´Á¥Z¼Æ: 92, »â°ì±Æ¦W: 9.78%)

The novel roles of YULINK in the migration, proliferation and glycolysis of pulmonary arterial smooth muscle cells: implications for pulmonary arterial hypertension
Yi-Chia Wu, Wei-Ting Wang, Ming-Chun Yang, Yu-Tsun Su, Jwu-Lai Yeh, Jong-Hau Hsu, Jiunn-Ren Wu - - 1 - Biological Research - BIOLOGICAL RESEARCH 2023;56(1):66
(IF: 6.7, Journal Ranking: 9, Number of Journals of this Field: 92, Ranking: 9.78%)

10

¶ÀáIËï­l¥Íª«KMUP-1´î½w¹êÅç©Ê¤ú©Pª¢¸g¥Ñ´î¤Ö¾½°©²Ó­M¤À¤Æ»Pµoª¢§@¥Î
³¢©Óµ¾, ±i¥»¾ì, ¶À¤W®¦, ®}¥ò»¨, ¤ý«Û¶¯, ¨¿¤ó³·»È, ¿à¬L¿«, ¸­¦Ë¨Ó* - - 1 - Frontiers in Pharmacology - FRONTIERS IN PHARMACOLOGY 2022 13¨÷(4´Á):821492­¶
(IF: 5.988, »â°ì±Æ¦W: 50, »â°ì´Á¥Z¼Æ: 279, »â°ì±Æ¦W: 17.92%)

Xanthine derivative KMUP-1 attenuates experimental periodontitis by reducing osteoclast differentiation and inflammation
Kuo CH, Zhang BH, Huang SE, Hsu JH, Wang YH, Nguyen TTN, Lai CH, Yeh JL* - - 1 - Frontiers in Pharmacology - FRONTIERS IN PHARMACOLOGY 2022;13(4):821492
(IF: 5.988, Journal Ranking: 50, Number of Journals of this Field: 279, Ranking: 17.92%)

11

¶ÀÍÁ¯À¦bÅé¥~©MÅ餺¹w¨¾¥­·Æ¦Ù²Ó­M¦åºÞ¶t¤Æªº¼ç¦b§@¥Î
Erna Sulistyowati, ®}¥ò»¨, §õ©q»T, ¶À¤W®¦, Widya Yanti Sihotang, §d¬±¨k, À¹¥ô®¥, ªL©ú©¾*, ¸­¦Ë¨Ó* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022 23¨÷(10´Á):5673­¶
(IF: 6.208, »â°ì±Æ¦W: 69, »â°ì´Á¥Z¼Æ: 296, »â°ì±Æ¦W: 23.31%)

Potential actions of baicalein for preventing vascular calcification of smooth muscle cells in vitro and in vivo
Erna Sulistyowati, Jong-Hau Hsu, Szu-Jung Lee, Shang-En Huang, Widya Yanti Sihotang, Bin-Nan Wu, Zen-Kong Dai, Ming-Chung Lin*, Jwu-Lai Yeh* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022;23(10):5673
(IF: 6.208, Journal Ranking: 69, Number of Journals of this Field: 296, Ranking: 23.31%)

12

Clinical Patterns of Traditional Chinese Medicine for Ischemic Heart Disease Treatment: A Population-Based Cohort Study
¤ý¶©ºÓ, ÃC¨Ø«º#, ¯Î¥@®p, ®}¥ò»¨*, ¸­¦Ë¨Ó* - - 1 - Medicina - MEDICINA-LITHUANIA 2022 58¨÷(7´Á):879­¶
(IF: 2.948, »â°ì±Æ¦W: 87, »â°ì´Á¥Z¼Æ: 172, »â°ì±Æ¦W: 50.58%)

Clinical Patterns of Traditional Chinese Medicine for Ischemic Heart Disease Treatment: A Population-Based Cohort Study
Lung-Shuo Wang, Pei-Tzu Yen#, Shih-Feng Weng, Jong-Hau Hsu*, Jwu-Lai Yeh* - - 1 - Medicina - MEDICINA-LITHUANIA 2022;58(7):879
(IF: 2.948, Journal Ranking: 87, Number of Journals of this Field: 172, Ranking: 50.58%)

13

ªÍªù¯ß°ªÀ£Á{§É«e¼Ð¹vªvÀø¤§±´°Q
Á©sÁ¾, ¤ýºû¾^, ¸­¦Ë¨Ó, ªL§§¦t, ³¢Ä£¤¯, §õ®ÑªY, «J©ú¾W, §d¯q¹Å* - - 1 - Biomedicines - BIOMEDICINES 2022 2022¨÷(10´Á):1415­¶
(IF: 4.757, »â°ì±Æ¦W: 87, »â°ì´Á¥Z¼Æ: 279, »â°ì±Æ¦W: 31.18%)

The Potential Application and Promising Role of Targeted Therapy in Pulmonary Arterial Hypertension
Meng-Chien Willie Hsieh #, Wei-Ting Wang #, Jwu-Lai Yeh , Chuang-Yu Lin , Yur-Ren Kuo #, Su-Shin Lee # , Ming-Feng Hou ,Yi-Chia Wu #,* - - 1 - Biomedicines - BIOMEDICINES 2022;2022(10):1415
(IF: 4.757, Journal Ranking: 87, Number of Journals of this Field: 279, Ranking: 31.18%)

14

°Ê¯ß¾ÉºÞ­«¶ìªº¼ç¦b¤À¤l¾÷¨î¡G¶W¶V«e¦C¸¢¯À
®}¦óÞ³,ªL®x·N,¼B©É¼y,¸­¦Ë¨Ó,®}¥ò»¨* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021 22¨÷(6´Á):3238­¶
(IF: 6.208, »â°ì±Æ¦W: 69, »â°ì´Á¥Z¼Æ: 296, »â°ì±Æ¦W: 23.31%)

Molecular Mechanisms Underlying Remodeling of Ductus Arteriosus: Looking Beyond the Prostaglandin Pathway
Ho-Wei Hsu, Ting-Yi Lin, Yi-Ching Liu, Jwu-Lai Yeh and Jong-Hau Hsu* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021;22(6):3238
(IF: 6.208, Journal Ranking: 69, Number of Journals of this Field: 296, Ranking: 23.31%)

15

¦åºÞºò±i¯ÀÂà´«酶2¿E¬¡¾¯¥i´î»´¥ªªÍ¤Á°£»PVEGF§í¨îªº¤j¹«¼Ò«¬¤¤ªºÄY­«ªÍ°Ê¯ß°ªÀ£
³¯©É¯u,ªL°x¦ö,¼B©É¼y,½²§Ó¤¯,®}¥ò»¨,¸­¦Ë¨Ó,§d¬±¨k*,À¹¥ô®¥* - - 1 - FRONTIERS IN MEDICINE - FRONTIERS IN MEDICINE 2021 8¨÷(-´Á):619133­¶
(IF: 5.091, »â°ì±Æ¦W: 28, »â°ì´Á¥Z¼Æ: 169, »â°ì±Æ¦W: 16.57%)

Angiotensin-Converting Enzyme 2 Activator Ameliorates Severe Pulmonary Hypertension in a Rat Model of Left Pneumonectomy Combined With VEGF Inhibition
I-Chen Chen, Jao-Yu Lin, Yi-Ching Liu, Chee-Yin Chai, Jwu-Lai Yeh, Jong-Hau Hsu, Bin-Nan Wu, Zen-Kong Dai - - 1 - FRONTIERS IN MEDICINE - FRONTIERS IN MEDICINE 2021;8(-):619133
(IF: 5.091, Journal Ranking: 28, Number of Journals of this Field: 169, Ranking: 16.57%)

16

KMUP-1«ì´_©PÃ䯫¸g·l¶Ë»¤µo­I®Ú¯«¸g¸`BKCa ³q¹D§í¨î§@¥Î
µ{¼s¸q, ·¨³Í´@, ÅÇ°·ºú, ¾G¥ÉµX, ¸­¦Ë¨Ó, À¹¥ô®¥*, §d¬±¨k* - - 1 - Cells - CELLS 2021 10¨÷(4´Á):949­¶
(IF: 7.666, »â°ì±Æ¦W: 51, »â°ì´Á¥Z¼Æ: 194, »â°ì±Æ¦W: 26.29%)

BKCa channel inhibition by peripheral nerve injury is restored by the xanthine derivative KMUP-1 in dorsal root ganglia
Kuang-I Cheng, Kan-Ting Yang, Chien-Lun Kung, Yu-Chi Cheng, Jwu-Lai Yeh, Zen-Kong Dai*, Bin-Nan Wu* - - 1 - Cells - CELLS 2021;10(4):949
(IF: 7.666, Journal Ranking: 51, Number of Journals of this Field: 194, Ranking: 26.29%)

17

In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
¶À¤W®¦, Erna Sulistyowati, »¯¥É­^, §d¬±¨k, À¹¥ô®¥, ®}¥ò»¨*, ¸­¦Ë¨Ó* - - 1 - Biomedicines - BIOMEDICINES 2021 9¨÷(6´Á):615­¶
(IF: 4.757, »â°ì±Æ¦W: 87, »â°ì´Á¥Z¼Æ: 279, »â°ì±Æ¦W: 31.18%)

In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis
Shang-En Huang, Erna Sulistyowati, Yu-Ying Chao, Bin-Nan Wu, Zen-Kong Dai, Jong-Hau Hsu*, Jwu-Lai Yeh* - - 1 - Biomedicines - BIOMEDICINES 2021;9(6):615
(IF: 4.757, Journal Ranking: 87, Number of Journals of this Field: 279, Ranking: 31.18%)

18

Cinaciguat ³q¹L¦åºÞµÎ±i©M§Ü­«¶ì¹w¨¾·s¥Í¤j¹«¥X¥Í«á°Ê¯ß¾ÉºÞÃö³¬
¬x·¶´Ñ, ¼B©É¼y, §d¬±¨k, ¸­¦Ë¨Ó*, ®}¥ò»¨* - - 1 - Frontiers in Physiology - FRONTIERS IN PHYSIOLOGY 2021 12¨÷(-´Á):661171­¶
(IF: 4.755, »â°ì±Æ¦W: 20, »â°ì´Á¥Z¼Æ: 81, »â°ì±Æ¦W: 24.69%)

Cinaciguat Prevents Postnatal Closure of Ductus Arteriosus by Vasodilation and Anti-remodeling in Neonatal Rats
Yu-Chi Hung, Yi-Ching Liu, Bin-Nan Wu, Jwu-Lai Yeh, Jong-Hau Hsu* - - 1 - Frontiers in Physiology - FRONTIERS IN PHYSIOLOGY 2021;12(-):661171
(IF: 4.755, Journal Ranking: 20, Number of Journals of this Field: 81, Ranking: 24.69%)

19

Loganin ¹w¨¾ CXCL12/CXCR4 ½Õ±±¯«¸g©Ê¯kµh³z¹L NLRP3µoª¢Åé¦b¯«¸g·l¶Ëªº¤j¹«
µ{¼s¸q, ³¯¤ßÄõ, ®}¥ò»¨, ¾G¥ÉµX, ±i·¶¯³, §õ«Ø¿³, ¸­¦Ë¨Ó, À¹¥ô®¥*, §d¬±¨k* - - 1 - PHYTOMEDICINE : INTERNATIONAL JOURNAL OF PHYTOTHERAPY AND PHYTOPHARMACOLOGY - PHYTOMEDICINE 2021 92¨÷(11´Á):153734­¶
(IF: 6.656, »â°ì±Æ¦W: 1, »â°ì´Á¥Z¼Æ: 30, »â°ì±Æ¦W: 3.33%)

Loganin prevents CXCL12/CXCR4-regulated neuropathic pain via the NLRP3 inflammasome axis in nerve-injured rats.
Kuang-I Cheng, Sin-Lan Chen, Jong-Hau Hsu, Yu-Chi Cheng, Yu-Chin Chang, Chien-Hsing Lee, Jwu-Lai Yeh, Zen-Kong Dai*, Bin-Nan Wu* - - 1 - PHYTOMEDICINE : INTERNATIONAL JOURNAL OF PHYTOTHERAPY AND PHYTOPHARMACOLOGY - PHYTOMEDICINE 2021;92(11):153734
(IF: 6.656, Journal Ranking: 1, Number of Journals of this Field: 30, Ranking: 3.33%)

20

Loganin ¹w¨¾ºC©Ê¯«¸gÀ£­¢·l¶Ë¤Þµo¯«¸g©Ê¯kµh³z¹L­°§C TNF-£\/IL-1£] »¤µoNF-£eB ¬¡¤Æ¤Î³\©ô²Ó­M¤§¥hÅèÀT¤Æ
Chu LW, µ{¼s¸q, Chen JY, ¾G¥ÉµX, ±i·¶¯³, ¸­¦Ë¨Ó, ®}¥ò»¨, À¹¥ô®¥*, §d¬±¨k* - - 1 - Phytomedicine - PHYTOMEDICINE 2020 67¨÷(-´Á):153166­¶
(IF: 5.34, »â°ì±Æ¦W: 22, »â°ì´Á¥Z¼Æ: 235, »â°ì±Æ¦W: 9.36%)

Loganin prevents chronic constriction injury-provoked neuropathic pain by reducing TNF-£\/IL-1£]-mediated NF-£eB activation and Schwann cell demyelination
Chu LW, Cheng KI, Chen JY, Cheng YC, Chang YC, Yeh JL, Hsu JH, Dai ZK*, Wu BN* - - 1 - Phytomedicine - PHYTOMEDICINE 2020;67(-):153166
(IF: 5.34, Journal Ranking: 22, Number of Journals of this Field: 235, Ranking: 9.36%)

21

Targeting vascular smooth muscle cell dysfunction with xanthine derivative KMUP-3 inhibits abdominal aortic aneurysm in mice
¿à¬L¿«, ±i瀞¤å, §õªÚ«º, ³¢©Óµ¾, ®}¥ò»¨, ¼B¤¤¥­, §dµØªL, ¸­¦Ë¨Ó* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2020 297¨÷(-´Á):16-24­¶
(IF: 5.162, »â°ì±Æ¦W: 14, »â°ì´Á¥Z¼Æ: 65, »â°ì±Æ¦W: 21.54%)

Targeting vascular smooth muscle cell dysfunction with xanthine derivative KMUP-3 inhibits abdominal aortic aneurysm in mice
Chao-Han Lai, Ching-Wen Chang, Ching-Wen Chang, Cheng-Hsiang Kuo, Jong-Hau Hsu, Jong-Hau Hsu, Hua-Lin Wu, Jwu-Lai Yeh* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2020;297(-):16-24
(IF: 5.162, Journal Ranking: 14, Number of Journals of this Field: 65, Ranking: 21.54%)

22

Data supporting the effects of xanthine derivative KMUP-3 on vascular smooth muscle cell calcification and abdominal aortic aneurysm in mice.
¿à¬L¿«, ±i瀞¤å, §õªÚ«º, ³¢©Óµ¾, ®}¥ò»¨, ¼B¤¤¥­, §dµØªL, ¸­¦Ë¨Ó* - - 9 - Data in Brief - 2020 30¨÷(3´Á):105550­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Data supporting the effects of xanthine derivative KMUP-3 on vascular smooth muscle cell calcification and abdominal aortic aneurysm in mice.
Chao-Han Lai, Ching-Wen Chang, Ching-Wen Chang, Cheng-Hsiang Kuo, Jong-Hau Hsu, Jong-Hau Hsu, Hua-Lin Wu, Jwu-Lai Yeh* - - 9 - Data in Brief - 2020;30(3):105550
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

23

Extracellular heat shock protein HSC70 protects against lipopolysaccharide-induced hypertrophic responses in rat cardiomyocytes
¸â¤¯¶©#,·¨¶¶¦¨#, ¼B©É¼y, ·¨·ç¦¨, ½²¾åµÓ, ¶À¤W®¦, ¸­¦Ë¨Ó*, ®}¥ò»¨* - - 1 - Biomedicine and Pharmacotherapy - BIOMEDICINE & PHARMACOTHERAPY 2020 128¨÷(0´Á):110370­¶
(IF: 4.545, »â°ì±Æ¦W: 42, »â°ì´Á¥Z¼Æ: 271, »â°ì±Æ¦W: 15.50%)

Extracellular heat shock protein HSC70 protects against lipopolysaccharide-induced hypertrophic responses in rat cardiomyocytes
Ren-Long Jan#, Shun-Cheng Yang#, Yi-Ching Liu, Rei-Cheng Yang, Siao-Ping Tsai, Shang-En Huang, Jwu-Lai Yeh*, Jong-Hau Hsu* - - 1 - Biomedicine and Pharmacotherapy - BIOMEDICINE & PHARMACOTHERAPY 2020;128(0):110370
(IF: 4.545, Journal Ranking: 42, Number of Journals of this Field: 271, Ranking: 15.50%)

24

Role of Extracellular Matrix in Pathophysiology of Patent Ductus Arteriosus: Emphasis on Vascular Remodeling
ªL®x·N,¸­¦Ë¨Ó,®}¥ò»¨* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21¨÷(13´Á):4761­¶
(IF: 5.923, »â°ì±Æ¦W: 67, »â°ì´Á¥Z¼Æ: 298, »â°ì±Æ¦W: 22.48%)

Role of Extracellular Matrix in Pathophysiology of Patent Ductus Arteriosus: Emphasis on Vascular Remodeling
Ting-Yi Lin#, Jwu-Lai Yeh, Jong-Hau Hsu* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(13):4761
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

25

Vasculoprotective effects of Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction via the NOXs-ROS-NF-£eB pathway in spontaneously hypertensive rats
Sulistyowati E, ¸â¤¯¶©#, ¼B²Qªâ, ³¯­^´I, §d¬±¨k, ®}¥ò»¨*, ¸­¦Ë¨Ó* - - 1 - Journal of Traditional and Complementary Medicine - JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE 2020 10¨÷(4´Á):378-388­¶
(IF: 4.5, »â°ì±Æ¦W: 8, »â°ì´Á¥Z¼Æ: 28, »â°ì±Æ¦W: 28.57%)

Vasculoprotective effects of Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction via the NOXs-ROS-NF-£eB pathway in spontaneously hypertensive rats
Sulistyowati E, Jan RL, Liou SF, Chen YF, Wu BN, Hsu JH*, Yeh JL* - - 1 - Journal of Traditional and Complementary Medicine - JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE 2020;10(4):378-388
(IF: 4.5, Journal Ranking: 8, Number of Journals of this Field: 28, Ranking: 28.57%)

26

¶À»G¾J¨¾¤îºû¥Í¯ÀD3©M¥§¥j¤B»¤¾É¤§¦åºÞ¶t¤Æ
¼B²Qªâ, ¨¿¤ó³·»È#, ®}¥ò»¨, º¸®R, ¶À¤W®¦, §d¬±¨k, ªL©ú©¾*, ¸­¦Ë¨Ó* - - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2020 9¨÷(10´Á):E956­¶
(IF: 6.312, »â°ì±Æ¦W: 60, »â°ì´Á¥Z¼Æ: 298, »â°ì±Æ¦W: 20.13%)

The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D Plus Nicotine.
Shu-Fen Liou, Thi Tuyet Ngan Nguyen, Jong-Hau Hsu, Erna Sulistyowati, Shang-En Huang, Bin-Nan Wu, Ming-Chung Lin*, Jwu-Lai Yeh* - - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2020;9(10):E956
(IF: 6.312, Journal Ranking: 60, Number of Journals of this Field: 298, Ranking: 20.13%)

27

The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
³¯©É¯u,ªL°x¦ö,¼B©É¼y,½²¦Ü¤¯,¸­¦Ë¨Ó,®}¥ò»¨,§d¬±¨k*,À¹¥ô®¥* - - 1 - International journal of medical sciences - INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 2020 17¨÷(16´Á):2594-2602­¶
(IF: 3.738, »â°ì±Æ¦W: 44, »â°ì´Á¥Z¼Æ: 169, »â°ì±Æ¦W: 26.04%)

The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
I-Chen Chen,Jao-Yu Lin,Yi-Ching Liu,Chee-Yin Chai,Jwu-Lai Yeh,Jong-Hau Hsu,Bin-Nan Wu*,Zen-Kong Dai* - - 1 - International journal of medical sciences - INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 2020;17(16):2594-2602
(IF: 3.738, Journal Ranking: 44, Number of Journals of this Field: 169, Ranking: 26.04%)

28

Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene
ªL¤ÖµY*, ¸­¦Ë¨Ó#, Tsai PC, Chang TH, Huang WC, Lee ST, Wassler M, Geng YJ, Sulistyowati E - - 1 - Translational Stroke Research - TRANSLATIONAL STROKE RESEARCH 2019 10¨÷(4´Á):413-427­¶
(IF: 5.78, »â°ì±Æ¦W: 22, »â°ì´Á¥Z¼Æ: 204, »â°ì±Æ¦W: 10.78%)

Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene
Lin SL*, Yeh JL, Tsai PC, Chang TH, Huang WC, Lee ST, Wassler M, Geng YJ, Sulistyowati E - - 1 - Translational Stroke Research - TRANSLATIONAL STROKE RESEARCH 2019;10(4):413-427
(IF: 5.78, Journal Ranking: 22, Number of Journals of this Field: 204, Ranking: 10.78%)

29

KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO-cGMP-MAPK Signaling Pathways
§õ©s­Û, Erna Sulistyowati, ®}¥ò»¨, ¶À¬f³ó, À¹¥ô®¥, §d¬±¨k, »¯¥É­^, ¸­¦Ë¨Ó* - - 1 - Molecules - MOLECULES 2019 24¨÷(7´Á):1376­¶
(IF: 3.267, »â°ì±Æ¦W: 70, »â°ì´Á¥Z¼Æ: 177, »â°ì±Æ¦W: 39.55%)

KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO-cGMP-MAPK Signaling Pathways
Meng-Luen Lee, Erna Sulistyowati, Jong-Hau Hsu, Bo-Yau Huang, Zen-Kong Dai, Bin-Nan Wu, Yu-Ying Chao, Jwu-Lai Yeh* - - 1 - Molecules - MOLECULES 2019;24(7):1376
(IF: 3.267, Journal Ranking: 70, Number of Journals of this Field: 177, Ranking: 39.55%)

30

Glucagon-Like Peptide-1 Receptor Agonist Attenuates Autophagy to Ameliorate Pulmonary Arterial Hypertension through Drp1/NOX- and Atg-5/Atg-7/Beclin-1/LC3£] Pathways
§d¯q¹Å, Wei-Ting Wang ,§õ®ÑªY, ³¢Ä£¤¯, Ya-Chin Wang , Shih-Jung Yen, §õ¬ü¤ë* ,¸­¦Ë¨Ó* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019 20¨÷(14´Á):3435­¶
(IF: 4.556, »â°ì±Æ¦W: 74, »â°ì´Á¥Z¼Æ: 297, »â°ì±Æ¦W: 24.92%)

Glucagon-Like Peptide-1 Receptor Agonist Attenuates Autophagy to Ameliorate Pulmonary Arterial Hypertension through Drp1/NOX- and Atg-5/Atg-7/Beclin-1/LC3£] Pathways
Wu YC, Wang WT, Lee SS,, Kuo YR, Wang YC, Yen SJ, Lee MY*, Yeh JL* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019;20(14):3435
(IF: 4.556, Journal Ranking: 74, Number of Journals of this Field: 297, Ranking: 24.92%)

31

¶ÀáIËï­l¥ÍKMUP-1¤ÏÂà°ª¿}¬r©Ê¬¡¤Æ¤§Kv³q¹D¸g¥ÑcAMP/PKA°T®§¸ô®|©ó¤j¹«¯Ø®q¤A«¬²Ó­M
§õ«Ø¿³, ¦¶§Ó¥Í, Tsai HJ, ¬_¨}­N, §õ­»§g, ¸­¦Ë¨Ó, ³¯¯]¿X, §d¬±¨k* - - 1 - Chemico-Biological Interactions - CHEMICO-BIOLOGICAL INTERACTIONS 2018 279¨÷(1´Á):171-176­¶
(IF: 3.296, »â°ì±Æ¦W: 75, »â°ì´Á¥Z¼Æ: 261, »â°ì±Æ¦W: 28.74%)

Xanthine-derived KMUP-1 reverses glucotoxicity-activated Kv channels through the cAMP/PKA signaling pathway in rat pancreatic £] cells
Lee CH, Chu CS, Tsai HJ, Ke LY, Lee HC, Yeh JL, Chen CH, Wu BN* - - 1 - Chemico-Biological Interactions - CHEMICO-BIOLOGICAL INTERACTIONS 2018;279(1):171-176
(IF: 3.296, Journal Ranking: 75, Number of Journals of this Field: 261, Ranking: 28.74%)

32

Molecular Mechanisms for Regulating Postnatal Ductus Arteriosus Closure
¬x·¶´Ñ,¸­¦Ë¨Ó,®}¥ò»¨* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018 19¨÷(7´Á):1861­¶
(IF: 3.687, »â°ì±Æ¦W: 52, »â°ì´Á¥Z¼Æ: 170, »â°ì±Æ¦W: 30.59%)

Molecular Mechanisms for Regulating Postnatal Ductus Arteriosus Closure
Hung YC, Yeh JL, Hsu JH* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018;19(7):1861
(IF: 3.687, Journal Ranking: 52, Number of Journals of this Field: 170, Ranking: 30.59%)

33

Exogenous heat shock Cognate protein 70 suppresses LPS-induced inflammation by down-regulating NF-£eB through MAPK and MMP-2/-9 pathways in macrophages
Sulistyowati E, §õ¬ü¤ë(¦@¦P²Ä¤@), §dµY¸R, ®}¥ò»¨, À¹¥ô®¥, §d¬±¨k, ªL©ú©¾*, ¸­¦Ë¨Ó* - - 1 - Molecules - MOLECULES 2018 23¨÷(9´Á):e2124­¶
(IF: 3.098, »â°ì±Æ¦W: 68, »â°ì´Á¥Z¼Æ: 170, »â°ì±Æ¦W: 40.00%)

Exogenous heat shock Cognate protein 70 suppresses LPS-induced inflammation by down-regulating NF-£eB through MAPK and MMP-2/-9 pathways in macrophages
Sulistyowati E, Lee MY, Wu LC, Hsu JH, Dai ZK, Wu BN, Lin MC*, Yeh JL* - - 1 - Molecules - MOLECULES 2018;23(9):e2124
(IF: 3.098, Journal Ranking: 68, Number of Journals of this Field: 170, Ranking: 40.00%)

34

B-type natriuretic peptide prevents postnatal closure of ductus arteriosus by both vasodilation and anti-remodeling in neonatal rats
¸­¦Ë¨Ó, §d«T¤¯(¦@¦P²Ä¤@), §d¬±¨k, ·¨¾åªÚ, À¹¥ô®¥, ¼B²Qªâ,®}¥ò»¨* - - 1 - CLINICAL SCIENCE - CLINICAL SCIENCE 2018 18¨÷(132´Á):2045-2058­¶
(IF: 5.22, »â°ì±Æ¦W: 17, »â°ì´Á¥Z¼Æ: 133, »â°ì±Æ¦W: 12.78%)

B-type natriuretic peptide prevents postnatal closure of ductus arteriosus by both vasodilation and anti-remodeling in neonatal rats
Yeh JL, Wu JR, Wu BN, Yang SF, Dai ZK, Liou SF, Hsu JH* - - 1 - CLINICAL SCIENCE - CLINICAL SCIENCE 2018;18(132):2045-2058
(IF: 5.22, Journal Ranking: 17, Number of Journals of this Field: 133, Ranking: 12.78%)

35

GPCR ½Õ±±ª«½èKMUP-1´î¤Ö¤T»Ä¥Ìªo¯×»W¿n¥]§tMAPKs/Akt/PPAR£^¤ÎPKA/PKG/HSL°T®§¦b3T3-L1«e¯×ªÕ²Ó­M
Liu CP, Chau PC, Chang CT, ¦wÄR±ö, ¸­¦Ë¨Ó, ³¯­^«T, §d¬±¨k* - - 1 - Molecules - MOLECULES 2018 23¨÷(10´Á):2433­¶
(IF: 3.098, »â°ì±Æ¦W: 68, »â°ì´Á¥Z¼Æ: 170, »â°ì±Æ¦W: 40.00%)

KMUP-1, a GPCR Modulator, Attenuates Triglyceride Accumulation Involved MAPKs/Akt/PPAR£^ and PKA/PKG/HSL Signaling in 3T3-L1 Preadipocytes
Liu CP, Chau PC, Chang CT, An LM, Yeh JL, Chen IJ, Wu BN* - - 1 - Molecules - MOLECULES 2018;23(10):2433
(IF: 3.098, Journal Ranking: 68, Number of Journals of this Field: 170, Ranking: 40.00%)

36

Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release
¨¯¥ú, Wei Z, Ji C, Zheng H, Gu J, Ma L, Huang W, Morris-Natschke SL, ¸­¦Ë¨Ó, Zhang R, Qin C, Wen L, Xing Z, Cao Y, Xia Q, Li K, Niu H, §õ°ê¶¯*, Huang W*. - - 1 - Free Radical Biology and Medicine - Free Radic Biol Med. 2017 pii S:0891¨÷(17´Á):30080-1.­¶
(IF: 5.784, »â°ì±Æ¦W: 14, »â°ì´Á¥Z¼Æ: 133, »â°ì±Æ¦W: 10.53%)

Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release
Xin G, Wei Z, Ji C, Zheng H, Gu J, Ma L, Huang W, Morris-Natschke SL, Yeh JL, Zhang R, Qin C, Wen L, Xing Z, Cao Y, Xia Q, Li K, Niu H, Lee KH, Huang W. - - 1 - Free Radical Biology and Medicine - Free Radic Biol Med. 2017;pii S:0891(17):30080-1.
(IF: 5.784, Journal Ranking: 14, Number of Journals of this Field: 133, Ranking: 10.53%)

37

Statins Ameliorate Pulmonary Hypertension Secondary to Left Ventricular Dysfunction Through the Rho-Kinase Pathway and NADPH Oxidase
³¯©É¯u, ÃÓ´Ö¤ß, §d¬±¨k, ½²§Ó¤¯, ¸­¦Ë¨Ó, ©P¥@µØ, ³¯­^«T, À¹¥ô®¥* - - 1 - Pediatric Pulmonology - Pediatr. Pulmonol. 2017 52¨÷(4´Á):443-457­¶
(IF: 2.758, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 121, »â°ì±Æ¦W: 15.70%)

Statins Ameliorate Pulmonary Hypertension Secondary to Left Ventricular Dysfunction Through the Rho-Kinase Pathway and NADPH Oxidase
I-Chen Chen, Mian-Shin Tan, Bin-Nan Wu, Chee-Yin Chai, Jwu-Lai Yeh, Shah-Hwa Chou, Ing-Jun Chen, Zen-Kong Dai* - - 1 - Pediatric Pulmonology - Pediatr. Pulmonol. 2017;52(4):443-457
(IF: 2.758, Journal Ranking: 19, Number of Journals of this Field: 121, Ranking: 15.70%)

38

Indonesian herbal medicine prevents hypertension-induced left ventricular hypertrophy by diminishing NADPH oxidase-dependent oxidative stress
Erna Sulistyowati, ®}¥ò»¨, ¾G·½Ùy, ±iªÚºa, ³¯­^´I*, ¸­¦Ë¨Ó* - - 1 - Oncotarget - Oncotarget 2017 8¨÷(49´Á):86784-86798­¶
(IF: 5.168, »â°ì±Æ¦W: 44, »â°ì´Á¥Z¼Æ: 217, »â°ì±Æ¦W: 20.28%)

Indonesian herbal medicine prevents hypertension-induced left ventricular hypertrophy by diminishing NADPH oxidase-dependent oxidative stress
Erna Sulistyowati, Jong-Hau Hsu, Yuan-Bin Cheng, Fang-Rong Chang, Ying-Fu Chen*, Jwu-Lai Yeh* - - 1 - Oncotarget - Oncotarget 2017;8(49):86784-86798
(IF: 5.168, Journal Ranking: 44, Number of Journals of this Field: 217, Ranking: 20.28%)

39

Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca(2+) sensitization
¼B¤¤¥­, ¸­¦Ë¨Ó, ¼B²Qªâ, §d¬±¨k, ³¯­^«T* - - 1 - Kaohsiung Journal of Medical Sciences - Kaohsiung J Med Sci 2016 32¨÷(2´Á):55-67­¶
(IF: 1, »â°ì±Æ¦W: 104, »â°ì´Á¥Z¼Æ: 124, »â°ì±Æ¦W: 83.87%)

Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca(2+) sensitization
Liu CP, Yeh JL, Liou SF, Wu BN, Chen IJ* - - 1 - Kaohsiung Journal of Medical Sciences - Kaohsiung J Med Sci 2016;32(2):55-67
(IF: 1, Journal Ranking: 104, Number of Journals of this Field: 124, Ranking: 83.87%)

40

Åè¨t¾®¦å酶½Õ¸`¯ÀÃþ¾®¶°¯À¥\¯à°Ï§í¨î­¹°©²Ó­M¥Í¦¨§@¥Î»Pµoª¢©Ê°©½è¬y¥¢
¾GÚzÀM, ¿à¬L¿«, Á¦¡¬w, ©P§u¬f, ¸­¦Ë¨Ó, ·¨¦ã­Û, ¤ý«Û¶¯, ¤ý¬L¤¯, ³¯±R®Ù, ¬I®Û¤ë, ¦ó¬üª~*, §dµØªL* - - 1 - Scientific Reports - SCI REP-UK 2016 ?6¨÷(-´Á):28340­¶
(IF: 5.228, »â°ì±Æ¦W: 7, »â°ì´Á¥Z¼Æ: 63, »â°ì±Æ¦W: 11.11%)

Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss
Tsung-Lin Cheng, Chao-Han Lai, Shyh-Jou Shieh, Yin-Bo Jou, Jwu-Lai Yeh, Ai-Lun Yang, Yan-Hsiung Wang, Chau-Zen Wang, Chung-Hwan Chen, Guey-Yueh Shi, Mei-Ling Ho*, Hua-Lin Wu* - - 1 - Scientific Reports - SCI REP-UK 2016;?6(-):28340
(IF: 5.228, Journal Ranking: 7, Number of Journals of this Field: 63, Ranking: 11.11%)

41

¶ÀáIËï­l¥Íª«¥iÂǥѬ¡¤Æ¤º¥Ö²Ó­M¤@®ñ¤Æ´á¦X酶¥H´î¤Ö¤º¥Ö«eÅX²Ó­M¦b¯Ê®ñ±¡ªp¤U©Ò»¤¾Éªº²Ó­M­ä¤`²{¶H
§d«T¤¯,®}¥ò»¨,À¹¥ô®¥,§d¬±¨k,³¯­^«T,¼B²Qªâ*,¸­¦Ë¨Ó* - - 1 - JOURNAL OF PHARMACY AND PHARMACOLOGY - J PHARM PHARMACOL 2016 68¨÷(6´Á):810-818­¶
(IF: 2.363, »â°ì±Æ¦W: 127, »â°ì´Á¥Z¼Æ: 255, »â°ì±Æ¦W: 49.80%)

Activation of endothelial NO synthase by a xanthine derivative ameliorates hypoxia-induced apoptosis in endothelial progenitor cells.
Wu JR, Hsu JH, Dai ZK, Wu BN, Chen IJ, Liou SF*, Yeh JL*. - - 1 - JOURNAL OF PHARMACY AND PHARMACOLOGY - J PHARM PHARMACOL 2016;68(6):810-818
(IF: 2.363, Journal Ranking: 127, Number of Journals of this Field: 255, Ranking: 49.80%)

42

Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway
§d«T¤¯,¸­¦Ë¨Ó(¦@¦P²Ä¤@),¼B²Qªâ,À¹¥ô®¥,§d¬±¨k,®}¥ò»¨* - - 1 - International Journal of Biological Sciences - INT J BIOL SCI 2016 12¨÷(9´Á):1063-1073­¶
(IF: 3.982, »â°ì±Æ¦W: 78, »â°ì´Á¥Z¼Æ: 289, »â°ì±Æ¦W: 26.99%)

Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway
Jiunn-Ren Wu, Jwu-Lai Yeh, Shu-Fen Liou, Zen-Kong Dai, Bin-Nan Wu, and Jong-Hau Hsu*. - - 1 - International Journal of Biological Sciences - INT J BIOL SCI 2016;12(9):1063-1073
(IF: 3.982, Journal Ranking: 78, Number of Journals of this Field: 289, Ranking: 26.99%)

43

Liraglutide prevents and reverses monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways
§õ¬ü¤ë, ½²©[Ä_, ®}¥ò»¨, ¨¯¿ü¼ý, §d«T¤¯*, ¸­¦Ë¨Ó* - - 1 - Scientific Reports - SCI REP-UK 2016 6¨÷(-´Á):31788­¶
(IF: 5.228, »â°ì±Æ¦W: 7, »â°ì´Á¥Z¼Æ: 63, »â°ì±Æ¦W: 11.11%)

Liraglutide prevents and reverses monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways
Lee MY, Tsai KB, Hsu JH, Shin SJ, Wu JR, Yeh JL - - 1 - Scientific Reports - SCI REP-UK 2016;6(-):31788
(IF: 5.228, Journal Ranking: 7, Number of Journals of this Field: 63, Ranking: 11.11%)

44

Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release
¨¯¥ú, Wei Z, Ji C, Zheng H, Gu J, Ma L, Huang W, Morris-Natschke SL, ¸­¦Ë¨Ó, Zhang R, Qin C, Wen L, Xing Z, Cao Y, Xia Q, Lu Y, Li K, Niu H*, §õ°ê¶¯*, Huang W* - - 1 - Scientific Reports - SCI REP-UK 2016 6¨÷(-´Á):36222­¶
(IF: 5.228, »â°ì±Æ¦W: 7, »â°ì´Á¥Z¼Æ: 63, »â°ì±Æ¦W: 11.11%)

Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release
Xin G, Wei Z, Ji C, Zheng H, Gu J, Ma L, Huang W, Morris-Natschke SL, Yeh JL, Zhang R, Qin C, Wen L, Xing Z, Cao Y, Xia Q, Lu Y, Li K, Niu H*, Lee KH*, Huang W* - - 1 - Scientific Reports - SCI REP-UK 2016;6(-):36222
(IF: 5.228, Journal Ranking: 7, Number of Journals of this Field: 63, Ranking: 11.11%)

45

3«×¿S¶Ë¤Þµo¯áÅ踡¨¤¹B°Ê¯«¸g¤¸²Ó­M­ä¤`, §¤°©¯«¸g¤Î¦Ù¦×µäÁY
§dª@¾ì, ¶À®ÑÂE, µ{¼s¸q, ½²§Ó¤¯, ¸­¦Ë¨Ó, §d©§¿þ, ®}©É±j*, ÃöáøÄR* - - 1 - Biomed Research International - BIOMED RES INT 2015 2015¨÷(-´Á):372819(1-9)­¶
(IF: 1.579, »â°ì±Æ¦W: 107, »â°ì´Á¥Z¼Æ: 163, »â°ì±Æ¦W: 65.64%)

Third-Degree Hindpaw Burn Injury Induced Apoptosis of Lumbar Spinal Cord Ventral Horn Motor Neurons and Sciatic Nerve and Muscle Atrophy in Rats
Sheng-HuaWu, Shu-Hung Huang, Kuang-I Cheng, Chee-Yin Chai, Jwu-Lai Yeh, Tai-ChengWu, Yi-Chiang Hsu*, and Aij-Lie Kwan* - - 1 - Biomed Research International - BIOMED RES INT 2015;2015(-):372819(1-9)
(IF: 1.579, Journal Ranking: 107, Number of Journals of this Field: 163, Ranking: 65.64%)

46

Xanthine ­l¥Íª« KMUP-1 ´î®z Serotonin ¤Þ°_ªÍ°Ê¯ß¦åºÞ¯U¯¶¤Î¹[Â÷¤l³q¹D§í¨î¬¡©Ê³z¹L PKC ¸ô®|
À¹¥ô®¥, Yu-Wei Liu, ®}¥ò»¨, ¸­¦Ë¨Ó, ³¯­^«T, §d«T¤¯*, §d¬±¨k* - - 1 - International Journal of Biological Sciences - INT J BIOL SCI 2015 11¨÷(6´Á):633-642­¶
(IF: 4.509, »â°ì±Æ¦W: 63, »â°ì´Á¥Z¼Æ: 290, »â°ì±Æ¦W: 21.72%)

The Xanthine Derivative KMUP-1 Attenuates Serotonin-Induced Vasoconstriction and K+-Channel Inhibitory Activity via the PKC Pathway in Pulmonary Arteries
Zen-Kong Dai, Yu-Wei Liu, Jong-Hau Hsu, Jwu-Lai Yeh, Ing-Jun Chen, Jiunn-Ren Wu, Bin-Nan Wu - - 1 - International Journal of Biological Sciences - INT J BIOL SCI 2015;11(6):633-642
(IF: 4.509, Journal Ranking: 63, Number of Journals of this Field: 290, Ranking: 21.72%)

47

Autologous adipose-derived stem cells attenuate muscular atrophy and protect spinal cord ventral horn motor neurons in an animal model of burn injury.
§dª@¾ì, ¶À®ÑÂE(¦@¦P²Ä¤@), ù©É­ë*, ½²§Ó¤¯, §õ®ÑªY,±i°ªµû,ªL©¯¹D,¿à¬K¥Í,¸­¦Ë¨Ó, Ãö½JÄR* - - 1 - CYTOTHERAPY - CYTOTHERAPY 2015 17¨÷(8´Á):1066-1075­¶
(IF: 3.293, »â°ì±Æ¦W: 42, »â°ì´Á¥Z¼Æ: 163, »â°ì±Æ¦W: 25.77%)

Autologous adipose-derived stem cells attenuate muscular atrophy and protect spinal cord ventral horn motor neurons in an animal model of burn injury.
Wu SH, Huang SH, Lo YC*, Chai CY, Lee SS, Chang KP, Lin SD, Lai CS, Yeh JL, Kwan AL*. - - 1 - CYTOTHERAPY - CYTOTHERAPY 2015;17(8):1066-1075
(IF: 3.293, Journal Ranking: 42, Number of Journals of this Field: 163, Ranking: 25.77%)

48

Fat Grafting in Burn Scar Alleviates Neuropathic Pain via Anti-Inflammation Effect in Scar and Spinal Cord.
¶À®ÑÂE,§dª@¾ì,§õ®ÑªY,±i°ªµû,½²§Ó¤¯,¸­¦Ë¨Ó,ªL©¯¹D,Ãö½JÄR,¤ý´f¥Á*,¿à¬K¥Í* - - 1 - PLoS One - PLOS ONE 2015 10¨÷(9´Á):e0137563(1-13)­¶
(IF: 3.234, »â°ì±Æ¦W: 9, »â°ì´Á¥Z¼Æ: 57, »â°ì±Æ¦W: 15.79%)

Fat Grafting in Burn Scar Alleviates Neuropathic Pain via Anti-Inflammation Effect in Scar and Spinal Cord.
Huang SH, Wu SH, Lee SS, Chang KP, Chai CY, Yeh JL, Lin SD, Kwan AL, David Wang HM, Lai CS. - - 1 - PLoS One - PLOS ONE 2015;10(9):e0137563(1-13)
(IF: 3.234, Journal Ranking: 9, Number of Journals of this Field: 57, Ranking: 15.79%)

49

KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3£], Calcineurin/NFATc4 and RhoA/ROCK Pathways
¼B²Qªâ, ®}¥ò»¨, ³¯«É®x, ³¯­^«T, ¸­¦Ë¨Ó* - - 1 - MOLECULES - MOLECULES 2015 20¨÷(6´Á):10435-10449­¶
(IF: 2.416, »â°ì±Æ¦W: 22, »â°ì´Á¥Z¼Æ: 58, »â°ì±Æ¦W: 37.93%)

KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3£], Calcineurin/NFATc4 and RhoA/ROCK Pathways
Liou SF, Hsu JH, Chen YT, Chen IJ, Yeh JL* - - 1 - MOLECULES - MOLECULES 2015;20(6):10435-10449
(IF: 2.416, Journal Ranking: 22, Number of Journals of this Field: 58, Ranking: 37.93%)

50

KMUP-1 Promotes Osteoblast Differentiation Through cAMP and cGMP Pathways and Signaling of BMP-2/Smad1/5/8 and Wnt/£]-Catenin
¼B²Qªâ, ®}¥ò»¨, ¦¶Äɼä, ªL«í¥°, ³¯­^«T, ¸­¦Ë¨Ó* - - 1 - JOURNAL OF CELLULAR PHYSIOLOGY - J CELL PHYSIOL 2015 230¨÷(9´Á):2038-2048­¶
(IF: 3.839, »â°ì±Æ¦W: 15, »â°ì´Á¥Z¼Æ: 83, »â°ì±Æ¦W: 18.07%)

KMUP-1 Promotes Osteoblast Differentiation Through cAMP and cGMP Pathways and Signaling of BMP-2/Smad1/5/8 and Wnt/£]-Catenin
Liou SF, Hsu JH, Chu HC, Lin HH, Chen IJ, Yeh JL* - - 1 - JOURNAL OF CELLULAR PHYSIOLOGY - J CELL PHYSIOL 2015;230(9):2038-2048
(IF: 3.839, Journal Ranking: 15, Number of Journals of this Field: 83, Ranking: 18.07%)

51

Cyclic guanosine monophosphate-enhancing reduces androgenic extracellular regulated protein kinases-phosphorylation/Rho kinase II-activation in benign prostate hyperplasia
¼B´Ñ»Ê, ­S¶®µ^, ù©É­ë, §d¬±¨k, ¸­¦Ë¨Ó, ³¯­^«T* - - 1 - International Journal of Urology - Int J Urol 2014 21¨÷(1´Á):87-92­¶
(IF: 1.734, »â°ì±Æ¦W: 35, »â°ì´Á¥Z¼Æ: 48, »â°ì±Æ¦W: 72.92%)

Cyclic guanosine monophosphate-enhancing reduces androgenic extracellular regulated protein kinases-phosphorylation/Rho kinase II-activation in benign prostate hyperplasia
Liu CM, Fan YC, Lo YC, Wu BN, Yeh JL, Chen IJ* - - 1 - International Journal of Urology - Int J Urol 2014;21(1):87-92
(IF: 1.734, Journal Ranking: 35, Number of Journals of this Field: 48, Ranking: 72.92%)

52

Autologous fat grafting alleviates burn-induced neuropathic pain in rats.
¶À®ÑÂE,§dª@¾ì,±i°ªµû,µ{¼s¸q,§õ®ÑªY,Ãö½JÄR,¸­¦Ë¨Ó,½²ÂE°ö,ªL©¯¹D,¿à¬K¥Í* - - 1 - PLASTIC AND RECONSTRUCTIVE SURGERY - Plast Reconstr Surg 2014 133¨÷(6´Á):1396-1405­¶
(IF: 3.328, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 204, »â°ì±Æ¦W: 9.31%)

Autologous fat grafting alleviates burn-induced neuropathic pain in rats.
Huang SH, Wu SH, Chang KP, Cheng KI, Lee SS, Kwan AL, Yeh JL, Tsai HP, Lin SD, Lai CS*. - - 1 - PLASTIC AND RECONSTRUCTIVE SURGERY - Plast Reconstr Surg 2014;133(6):1396-1405
(IF: 3.328, Journal Ranking: 19, Number of Journals of this Field: 204, Ranking: 9.31%)

53

B«¬§Q¶uàÈ肽©óªÍ¦åºÞ¥­·Æ¦Ù²Ó­M¤§§Ü¼W¥Í»P§Ü¾E±p§@¥Î
®}¥ò»¨,¼B²Qªâ,·¨¥Í·£,§d¬±¨k,À¹¥ô®¥,³¯­^«T,¸­¦Ë¨Ó*,§d«T¤¯* - - 1 - Pediatric Pulmonology - PEDIATR PULM 2014 49¨÷(8´Á):734-744­¶
(IF: 2.297, »â°ì±Æ¦W: 28, »â°ì´Á¥Z¼Æ: 118, »â°ì±Æ¦W: 23.73%)

B-type Natriuretic Peptide Inhibits Angiotensin ¢º-induced Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells
Jong-Hau Hsu, Shu-Fen Liou, San-Nan Yang, Bin-Nan Wu, Zen-Kong Dai, Ing-Jun Chen, Jwu-Lai Yeh, Jiunn-Ren Wu* - - 1 - Pediatric Pulmonology - PEDIATR PULM 2014;49(8):734-744
(IF: 2.297, Journal Ranking: 28, Number of Journals of this Field: 118, Ranking: 23.73%)

54

Dual ELE/NEP§í¨î¥i§ïµ½¥D°Ê¯ßÁY¯¶ª¬ªp³y¦¨¤ß«Ç¥¢±`¤§µÎ±i¥\¯à¥¢±`¤Î¤ß«Ç¦A¼Ò¤Æ
ÃÓ´Ö¤ß,§d¬±¨k,³¯©É¯u,½²´¼¤¯,©P¥@µØ,¸­¦Ë¨Ó,³¯­^«T,§d«T¤¯,Arco Y Jeng,À¹¥ô®¥* - - 1 - EXPERIMENTAL & CLINICAL CARDIOLOGY - EXP CLIN CARDIOL 2014 20¨÷(7´Á):358-368­¶
(IF: 0.758, »â°ì±Æ¦W: 111, »â°ì´Á¥Z¼Æ: 125, »â°ì±Æ¦W: 88.80%)

Dual ELE/NEP inhibition improved diastolic function and ameliorated cardiac remodeling in rats with myocardial dysfunction secondary to pressure overload by aortic banding
Mian-Shin Tan, Bin-Nan Wu, I-Chen Chen, Chee-Yin Chai, Shah-Hwa Chou, Jwu-Lai Yeh, Ing-Jun Chen, Jiunn-Ren Wu, Arco Y Jeng, Zen-Kong Dai* - - 1 - EXPERIMENTAL & CLINICAL CARDIOLOGY - EXP CLIN CARDIOL 2014;20(7):358-368
(IF: 0.758, Journal Ranking: 111, Number of Journals of this Field: 125, Ranking: 88.80%)

55

Baicalein Inhibits HMGB1 Release and MMP-2/-9 Expression in Lipopolysaccharide-Induced Cardiac Hypertrophy
³¯Ãh¥Á,¼B²Qªâ,®}¥ò»¨,³¯ÃÙ¦p,¾GÚzÀM,ªô»F°ò*,¸­¦Ë¨Ó* - - 1 - AMERICAN JOURNAL OF CHINESE MEDICINE - AM J CHINESR MED 2014 42¨÷(4´Á):785-797­¶
(IF: 2.625, »â°ì±Æ¦W: 3, »â°ì´Á¥Z¼Æ: 22, »â°ì±Æ¦W: 13.64%)

Baicalein Inhibits HMGB1 Release and MMP-2/-9 Expression in Lipopolysaccharide-Induced Cardiac Hypertrophy
Huai-Min Chen, Shu-Fen Lioud, Jong-Hau Hsu, Tsan-Ju Cheng,Tsung-Lin Cheng, Chaw-Chi Chiu,Jwu-Lai Yeh - - 1 - AMERICAN JOURNAL OF CHINESE MEDICINE - AM J CHINESR MED 2014;42(4):785-797
(IF: 2.625, Journal Ranking: 3, Number of Journals of this Field: 22, Ranking: 13.64%)

56

Baicalein, an active component of Scutellaria baicalensis Georgi, prevents lysophosphatidylcholine-induced cardiac injury by reducing reactive oxygen species production, calcium overload and apoptosis via MAPK pathways.
³¯Ãh¥Á,®}¥ò»¨(¦@¦P²Ä¤@),¼B²Qªâ,³¯ÃÙ¦p,Chen LY, ªô»F°ò*,¸­¦Ë¨Ó* - - 1 - BMC Complementary and Alternative Medicine - BMC COMPLEM ALTERN M 2014 14¨÷(-´Á):233(1-10)­¶
(IF: 1.877, »â°ì±Æ¦W: 8, »â°ì´Á¥Z¼Æ: 22, »â°ì±Æ¦W: 36.36%)

Baicalein, an active component of Scutellaria baicalensis Georgi, prevents lysophosphatidylcholine-induced cardiac injury by reducing reactive oxygen species production, calcium overload and apoptosis via MAPK pathways.
Chen HM, Hsu JH, Liou SF, Chen TJ, Chen LY, Chiu CC*,Yeh JL* - - 1 - BMC Complementary and Alternative Medicine - BMC COMPLEM ALTERN M 2014;14(-):233(1-10)
(IF: 1.877, Journal Ranking: 8, Number of Journals of this Field: 22, Ranking: 36.36%)

57

Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
®}¥ò»¨,·¨·ç¦¨,Lin, Shih-Jen,¼B²Qªâ,À¹¥ô®¥,¸­¦Ë¨Ó,§d«T¤¯* - - 1 - SHOCK - SHOCK 2014 42¨÷(6´Á):540-7­¶
(IF: 2.732, »â°ì±Æ¦W: 39, »â°ì´Á¥Z¼Æ: 204, »â°ì±Æ¦W: 19.12%)

Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Hsu JH1, Yang RC, Lin SJ, Liou SF, Dai ZK, Yeh JL, Wu JR. - - 1 - SHOCK - SHOCK 2014;42(6):540-7
(IF: 2.732, Journal Ranking: 39, Number of Journals of this Field: 204, Ranking: 19.12%)

58

¤º¥Ö¤@®ñ¤Æ´á¦X¦¨酶«P¶iG³J¥Õµ²¦X¨üÅé«ú§Ü¾¯§í¨îªÍ°Ê¯ß°ª¦åÀ£¦b³¥¦Ê²üÆP¼Ò¦¡¬OÂÇ¥ÑET-1¬ÛÃö¤ÎET-1¤£¬ÛÃöªº¸ô¶i
¼B¤¤¥­,À¹¥ô®¥,¶À«Ø¿Å,¸­¦Ë¨Ó,§d¬±¨k,§d«T¤¯,³¯­^«T* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG J MED SCI 2014 30¨÷(6´Á):267-278­¶
(IF: 0.805, »â°ì±Æ¦W: 102, »â°ì´Á¥Z¼Æ: 124, »â°ì±Æ¦W: 82.26%)

Endothelial nitric oxide synthase-enhancing G-protein coupled receptor antagonist inhibits pulmonary artery hypertension by endothelin-1-dependent and endothelin-1-independent pathways in a monocrotaline model.
Chung-Pin Liu, Zen-Kong Dai, Chein-Heng Huang, Jwu-Lai Yeh, Bin-Nan Wu, Jiunn-Ren Wu, Ing-Jun Chen* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG J MED SCI 2014;30(6):267-278
(IF: 0.805, Journal Ranking: 102, Number of Journals of this Field: 124, Ranking: 82.26%)

59

No donor KMUP-1 improves hepatic ischemia-reperfusion and hypoxic cell injury by inhibiting oxidative stress and pro-inflammatory signaling.
³¢¥\·¢,§d¬±¨k,ªô®¦­§,´¿²M«T,¸­¦Ë¨Ó,¼B¤¤¥­,½²§Ó¤¯,³¯­^«T* - - 1 - INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY - INT J IMMUNOPATH PH 2013 26¨÷(1´Á):93-106­¶
(IF: 2.99, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 79, »â°ì±Æ¦W: 24.05%)

No donor KMUP-1 improves hepatic ischemia-reperfusion and hypoxic cell injury by inhibiting oxidative stress and pro-inflammatory signaling.
Kuo KK, Wu BN, Chiu EY, Tseng CJ, Yeh JL, Liu CP, Chai CY, Chen IJ*. - - 1 - INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY - INT J IMMUNOPATH PH 2013;26(1):93-106
(IF: 2.99, Journal Ranking: 19, Number of Journals of this Field: 79, Ranking: 24.05%)

60

Lercanidipine and labedipinedilol-A attenuate lipopolysaccharide/interferon-£^-induced inflammation in rat vascular smooth muscle cells through inhibition of HMGB1 release and MMP-2, 9 activities
¸­¦Ë¨Ó, ®}¥ò»¨, ±ç¦Ü¤¤, ³¯­^«T, ¼B²Qªâ* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2013 226¨÷(2´Á):364-372­¶
(IF: 4.086, »â°ì±Æ¦W: 12, »â°ì´Á¥Z¼Æ: 66, »â°ì±Æ¦W: 18.18%)

Lercanidipine and labedipinedilol-A attenuate lipopolysaccharide/interferon-£^-induced inflammation in rat vascular smooth muscle cells through inhibition of HMGB1 release and MMP-2, 9 activities
Yeh J.L., Hsu J.H., Liang J.C., Chen I.J., Liou S.F.* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2013;226(2):364-372
(IF: 4.086, Journal Ranking: 12, Number of Journals of this Field: 66, Ranking: 18.18%)

61

KMUP-1 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss: Roles of MAPKs, Akt, NF-£eB and Calcium/Calcineurin/NFATc1 Pathways
¼B²Qªâ, ®}¥ò»¨, ªL©É§D, ¦ó¬üª~, ®}¨Ø®S, ³¯«Wª³, ³¯­^«T, ¸­¦Ë¨Ó* - - 1 - PLoS One - PLOS ONE 2013 8¨÷(7´Á):e69468­¶
(IF: 3.73, »â°ì±Æ¦W: 7, »â°ì´Á¥Z¼Æ: 56, »â°ì±Æ¦W: 12.50%)

KMUP-1 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss: Roles of MAPKs, Akt, NF-£eB and Calcium/Calcineurin/NFATc1 Pathways
Liou SF, Hsu JH, Lin IL, Ho ML, Hsu PC, Chen LW, Chen IJ, Yeh JL*. - - 1 - PLoS One - PLOS ONE 2013;8(7):e69468
(IF: 3.73, Journal Ranking: 7, Number of Journals of this Field: 56, Ranking: 12.50%)

62

¤T¶ÀÂm¤ß´ö«OÅ@¤ßŦ§Ü¯Ê®ñ¦Aµ¹®ñ¶Ë®`¬O¸g¥Ñ§í¨î®ñ¤ÆÀ£¤O¤Þ°_²Ó­Mµ{¦¡­ä¤`
¼B²Qªâ, ®}¥ò»¨, ±ç¦Ü¤¤, ¬_¶£¤¯, ³¯­^«T, §d«T¤¯, ¸­¦Ë¨Ó* - - 1 - Journal of Natural Medicines - J NAT MED-TOKYO 2012 66¨÷(2´Á):311-320­¶
(IF: 1.389, »â°ì±Æ¦W: 190, »â°ì´Á¥Z¼Æ: 261, »â°ì±Æ¦W: 72.80%)

San-Huang-Xie-Xin-Tang protects cardiomyocytes against hypoxia/reoxygenation injury via inhibition of oxidative stress-induced apoptosis
Liou SF, Hsu JH, Liang JC, Ke HJ, Chen IJ, Wu JR, Yeh JL*. - - 1 - Journal of Natural Medicines - J NAT MED-TOKYO 2012;66(2):311-320
(IF: 1.389, Journal Ranking: 190, Number of Journals of this Field: 261, Ranking: 72.80%)

63

KMUP-1 inhibits hypertension-induced left ventricular hypertrophy through regulation of nitric oxide synthases, ERK1/2, and calcineurin.
¸­¦Ë¨Ó, ¼B¤¤¥­, ®}¥ò»¨, ´¿²M«T, §dªÃ¾§, ¤ý©É¶®, §d«T¤¯, ³¯­^«T* - - 1 - Kaohsiung J Med Sci. - KAOHSIUNG J MED SCI 2012 28¨÷(11´Á):567-576­¶
(IF: 0.474, »â°ì±Æ¦W: 92, »â°ì´Á¥Z¼Æ: 106, »â°ì±Æ¦W: 86.79%)

KMUP-1 inhibits hypertension-induced left ventricular hypertrophy through regulation of nitric oxide synthases, ERK1/2, and calcineurin
Yeh JL, Liu CP, Hsu JH, Tseng CJ, Wu PJ, Wang YY, Wu JR, Chen IJ*. - - 1 - Kaohsiung J Med Sci. - KAOHSIUNG J MED SCI 2012;28(11):567-576
(IF: 0.474, Journal Ranking: 92, Number of Journals of this Field: 106, Ranking: 86.79%)

64

Attenuation of pulmonary hypertension secondary to left ventricular dysfunction in the rat by Rho-kinase inhibitor fasudil
À¹¥ô®¥,§d¬±¨k,³¯©É¯u,½²§Ó¤¯,§d«T¤¯,©P¥@µØ,¸­¦Ë¨Ó,³¯­^«T,ÃÓ´Ö¤ß* - - 1 - Peidatric Pulmonology - PEDIATR PULM 2011 46¨÷(1´Á):45-59­¶
(IF: 1.816, »â°ì±Æ¦W: 32, »â°ì´Á¥Z¼Æ: 94, »â°ì±Æ¦W: 34.04%)

Attenuation of pulmonary hypertension secondary to left ventricular dysfunction in the rat by Rho-kinase inhibitor fasudil
Zen-Kong Dai, Bin-Nan Wu, I-Chen Chen, Chee-Yin Chai , Jiunn-Ren Wu , Shah-Hwa Chou, Jwu-Lai Yeh, Ing-Jun Chen, Mian-Shin Tan* - - 1 - Peidatric Pulmonology - PEDIATR PULM 2011;46(1):45-59
(IF: 1.816, Journal Ranking: 32, Number of Journals of this Field: 94, Ranking: 34.04%)

65

KMUP-3 attenuates ventricular remodelling after myocardial infarction through eNOS enhancement and restoration of MMP-9/TIMP-1 balance
¼B¤¤¥­,¸­¦Ë¨Ó,§d¬±¨k, ½²§Ó¤¯,³¯­^«T,¿à¤å¼w* - - 1 - British Journal of Pharmacology - BRIT J PHARMACOL 2011 162¨÷(1´Á):126-135­¶
(IF: 5.204, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 236, »â°ì±Æ¦W: 8.05%)

KMUP-3 attenuates ventricular remodelling after myocardial infarction through eNOS enhancement and restoration of MMP-9/TIMP-1 balance
Liu CP, Yeh JL, Wu BN, Chai CY, Chen IJ, Lai WT* - - 1 - British Journal of Pharmacology - BRIT J PHARMACOL 2011;162(1):126-135
(IF: 5.204, Journal Ranking: 19, Number of Journals of this Field: 236, Ranking: 8.05%)

66

Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis
®}¥ò»¨,§d«T¤¯,¼B²Qªâ,³¯Ãh¥Á,À¹¥ô®¥ ³¯­^«T,¸­¦Ë¨Ó* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2011 0¨÷(0´Á):0­¶
(IF: 4.522, »â°ì±Æ¦W: 9, »â°ì´Á¥Z¼Æ: 60, »â°ì±Æ¦W: 15.00%)

Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis
Jong-Hau Hsu, Jiunn-Ren Wu, Shu-Fen Liou, Huai-Min Chen, Zen-Kong Dai, Ing-Jun Chen, Jwu-Lai Yeh* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2011;0(0):0
(IF: 4.522, Journal Ranking: 9, Number of Journals of this Field: 60, Ranking: 15.00%)

67

Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kB and AP-1 through inhibition of MAPKs and Akt/IkBa signaling pathways in macrophages
¸­¦Ë¨Ó, ®}¥ò»¨, ¬x­§µÎ, §d«T¤¯, ±ç¦Ü¤¤, §d¬±¨k, ³¯­^«T, ¼B²Qªâ* - - 1 - International Journal of Immunopathology and Pharmacology - INT J IMMUNOPATH PH 2011 24¨÷(2´Á):345-356­¶
(IF: 3.061, »â°ì±Æ¦W: 51, »â°ì´Á¥Z¼Æ: 128, »â°ì±Æ¦W: 39.84%)

Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kB and AP-1 through inhibition of MAPKs and Akt/IkBa signaling pathways in macrophages
Jwu-Lai Yeh, Jong-Hau Hsu, Yu-Shu Hong, Jiunn-Ren Wu, Jyh-Chong Liang, Bin-Nan Wu, Ing-Jun Chen and Shu-Fen Liou* - - 1 - International Journal of Immunopathology and Pharmacology - INT J IMMUNOPATH PH 2011;24(2):345-356
(IF: 3.061, Journal Ranking: 51, Number of Journals of this Field: 128, Ranking: 39.84%)

68

Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis
®}¥ò»¨ , §d«T¤¯(¦@¦P²Ä¤@) , ¼B²Qªâ , ³¯Ãh¥Á ,À¹¥ô®¥, ³¯­^«T , ¸­¦Ë¨Ó* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2011 217¨÷(22´Á):379-86­¶
(IF: 4.086, »â°ì±Æ¦W: 12, »â°ì´Á¥Z¼Æ: 66, »â°ì±Æ¦W: 18.18%)

Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis
Hsu JH, Wu JR, Liou SF, Chen HM, Dai ZK, Chen IJ, Yeh JL* - - 1 - Atherosclerosis - ATHEROSCLEROSIS 2011;217(22):379-86
(IF: 4.086, Journal Ranking: 12, Number of Journals of this Field: 66, Ranking: 18.18%)

69

¤T¶ÀÂm¤ß´ö¨¾¤î¤j¹«¤ßŦ¸g¯Ê®ñ¦Aµ¹®ñ¤Þ°_¤§²Ó­M­ä¤`¬O¸g¥ÑeNOS©MMAPK¸ô®|
¼B²Qªâ, ¬_¶£¤¯,, ®}¥ò»¨, ±ç¦Ü¤¤, ªL«í¥°, ³¯­^«T, ¸­¦Ë¨Ó* - - 1 - Evid Based Complement Alternat Med - EVID-BASED COMPL ALT 2011 2011¨÷(2011´Á):915051­¶
(IF: 2.964, »â°ì±Æ¦W: 3, »â°ì´Á¥Z¼Æ: 19, »â°ì±Æ¦W: 15.79%)

San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways
Liou SF, Ke HJ, Hsu JH, Liang JC, Lin HH, Chen IJ, Yeh JL*. - - 1 - Evid Based Complement Alternat Med - EVID-BASED COMPL ALT 2011;2011(2011):915051
(IF: 2.964, Journal Ranking: 3, Number of Journals of this Field: 19, Ranking: 15.79%)

70

Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis.
®}¥ò»¨ , §d«T¤¯ , ¼B²Qªâ , ³¯Ãh¥Á , ³¯­^«T , ¸­¦Ë¨Ó* - - 0 - ATHEROSCLEROSIS - ATHEROSCLEROSIS 2011 217¨÷(2´Á):379-86­¶
(IF: 4.086, »â°ì±Æ¦W: 12, »â°ì´Á¥Z¼Æ: 66, »â°ì±Æ¦W: 18.18%)

Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis.
Hsu JH, Wu JR, Liou SF, Chen HM, Dai ZK, Chen IJ, Yeh JL* - - 0 - ATHEROSCLEROSIS - ATHEROSCLEROSIS 2011;217(2):379-86
(IF: 4.086, Journal Ranking: 12, Number of Journals of this Field: 66, Ranking: 18.18%)

71

KMUP-1¸g¥ÑNO/cGMP/PKG©MERK1/2/calcineurin A¸ô®|´î§Cisoprenaline»¤¾É¤j¹«ªº¤ß¦ÙªÎ«p
¸­¦Ë¨Ó, ®}¥ò»¨, §dªÃ¾§, ¼B²Qªâ, ¼B¤¤¥­, ³¯­^«T, §d¬±¨k, À¹¥ô®¥, §d«T¤¯* - - 1 - British Journal of Pharmacology - BRIT J PHARMACOL 2010 159¨÷(5´Á):1151-1160­¶
(IF: 5.204, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 236, »â°ì±Æ¦W: 8.05%)

KMUP-1 attenuates isoproterenol-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways
Yeh J.L., Hsu J.H., Wu P.J., Liou S.F., Liu C.P., Chen I.J., Wu B.N., Dai Z.K., Wu J.R.* - - 1 - British Journal of Pharmacology - BRIT J PHARMACOL 2010;159(5):1151-1160
(IF: 5.204, Journal Ranking: 19, Number of Journals of this Field: 236, Ranking: 8.05%)

72

¯ùÆP­l¥Íª«KMUP-1¸g¥ÑNO/cGMP¨Ì¿à©Ê§í¨îRhoA/Rho kinase ªí²{ªvÀøªÍ°ªÀ£
Áé¼z¸©, À¹¥ô®¥, §d¬±¨k, ¸­¦Ë¨Ó, ½²§Ó¤¯ , ¦¶¥ú¿³, ¼B¤¤¥­, ³¯­^«T* - - 1 - British Journal of Pharmacology - BRIT J PHARMACOL 2010 160¨÷(4´Á):971¡V986­¶
(IF: 4.925, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 249, »â°ì±Æ¦W: 7.63%)

The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase
Hui-Hsuan Chung, Zen-Kong Dai, Bin-Nan Wu, Jwu-Lai Yeh, Chee-Yin Chai, Koung-Shing Chu, Chung-Pin Liu, and Ing-Jun Chen* - - 1 - British Journal of Pharmacology - BRIT J PHARMACOL 2010;160(4):971¡V986
(IF: 4.925, Journal Ranking: 19, Number of Journals of this Field: 249, Ranking: 7.63%)

73

KMUP-1 ¸g¥Ñ serotonin ¨üÅé/transporter »P NO synthase ¤Î §í¨î RhoA »P AKT/ERK ÁC»Ä¤Æ­°§CªÍ°Ê¯ß¼W¥Í
Áé¼z¸©, À¹¥ô®¥, §d¬±¨k, ¸­¦Ë¨Ó, ½²§Ó¤¯ , ¦¶¥ú¿³, ¼B¤¤¥­, ³¯­^«T* - - 1 - Vascular pharmacology - CURR VASC PHARMACOL 2010 53¨÷(5-6´Á):239-249­¶
(IF: 4.62, »â°ì±Æ¦W: 26, »â°ì´Á¥Z¼Æ: 256, »â°ì±Æ¦W: 10.16%)

KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation
Hui-Hsuan Chung, Zen-Kong Dai, Bin-Nan Wu, Jwu-Lai Yeh, Chee-Yin Chai, Koung-Shing Chu, Chung-Pin Liu, and Ing-Jun Chen* - - 1 - Vascular pharmacology - CURR VASC PHARMACOL 2010;53(5-6):239-249
(IF: 4.62, Journal Ranking: 26, Number of Journals of this Field: 256, Ranking: 10.16%)

74

Protective effects if a dual endothelin converting enzyme/neutral endopeptidase inhibitor on the development of pulmonary hypertension secondary to cardiac dysfunction in the rat
À¹¥ô®¥, Á¬³¬L, ½²§Ó¤¯, §d«T¤¯, ©P¥@µØ, §d¬±¨k, ¸­¦Ë¨Ó, ³¯­^«T, ³¯´Ö¤ß* - - 1 - Pediatr Pulmonary - PEDIATR PULM 2010 45¨÷(0´Á):1076-1085­¶
(IF: 1.816, »â°ì±Æ¦W: 32, »â°ì´Á¥Z¼Æ: 94, »â°ì±Æ¦W: 34.04%)

Protective effects if a dual endothelin converting enzyme/neutral endopeptidase inhibitor on the development of pulmonary hypertension secondary to cardiac dysfunction in the rat
Dai Zen-Kong, Chong-Chao Hsieh,Chee-Yin Chai, Jiunn-Ren Wu, Arco Y Jeng, Shah-Hwa Chou, Bin-Nan Wu, Jwu-Lai Yeh, Ing-Jun Chen, Mian-Shin Tan - - 1 - Pediatr Pulmonary - PEDIATR PULM 2010;45(0):1076-1085
(IF: 1.816, Journal Ranking: 32, Number of Journals of this Field: 94, Ranking: 34.04%)

75

Protective effects of a dual endothelin converting enzyme/neutral endothpeptidase inhibitor on the development of pulmonary hypertension secondary to cardiac dysfunction in the rat
À¹¥ô®¥,Á¬³¬L,½²§Ó¤¯, §d«T¤¯,©P¥@µØ,§d¬±¨k,¸­¦Ë¨Ó,³¯­^«T,ÃÓ´Ö¤ß* - - 1 - Pediatric pulmonary - PEDIATR PULM 2010 45¨÷(11´Á):1076-85­¶
(IF: 1.816, »â°ì±Æ¦W: 32, »â°ì´Á¥Z¼Æ: 94, »â°ì±Æ¦W: 34.04%)

Protective effects of a dual endothelin converting enzyme/neutral endothpeptidase inhibitor on the development of pulmonary hypertension secondary to cardiac dysfunction in the rat
Dai ZK, Hsieh CC, Chai CY, Wu JR, Jeng AY, Chou SH, Wu BN, Yeh JL, Chen IJ, Tan MS* - - 1 - Pediatric pulmonary - PEDIATR PULM 2010;45(11):1076-85
(IF: 1.816, Journal Ranking: 32, Number of Journals of this Field: 94, Ranking: 34.04%)

76

Lercanidipine§í¨î¦åºÞ¥­·Æ¦Ù²Ó­M¼W¥Í©M·s¥Í¤º¼hªº§Î¦¨¬O¸g¥Ñ´î§C¦Û¥Ñ°ò¤Î¥h¬¡¤ÆRas-ERK1/2°T®§¸ô®|
§d«T¤¯,¼B²Qªâ,ªLªY¾ì,½²§Ó¤¯,À¹¥ô®¥.±ç¦Ü¤¤,³¯­^«T,¸­¦Ë¨Ó* - - 1 - Pharmacological Research - PHARMACOL RES 2009 59¨÷(1´Á):48-56­¶
(IF: 3.929, »â°ì±Æ¦W: 41, »â°ì´Á¥Z¼Æ: 236, »â°ì±Æ¦W: 17.37%)

Lercanidipine inhibits vascular smooth muscle cell proliferation and neointimal formation via reducing intracellular reactive oxygen species and inactivating Ras-ERK1/2 signaling
Jiunn-Ren Wu, Shu-Fen Liou, Shin-Wha Lin, Chee-Yin Chai, Zen-Kong Dai, Jhy-Chong Liang, Ing-Jun Chen, Jwu-Lai Yeh* - - 1 - Pharmacological Research - PHARMACOL RES 2009;59(1):48-56
(IF: 3.929, Journal Ranking: 41, Number of Journals of this Field: 236, Ranking: 17.37%)

77

¤@­Ó¿ï¾Ü©Ê¥Ò¤@«¬µÇ¤W¸¢¯À©Ê¨üÅéªýÂ_¾¯Labedipinedilol-A§í¨îÄáÅ@¸¢Àù²Ó­M¼W¥Í¬O¬ÛÃö©ó²Ó­M¥Íªø¶g´Á°±¤î©M²Ó­M­ä¤`
¼B²Qªâ,ªL«í¥°,±ç¦Ü¤¤,³¯­^«T,¸­¦Ë¨Ó* - - 1 - Toxicology - TOXICOLOGY 2009 256¨÷(1-2´Á):13-24­¶
(IF: 3.241, »â°ì±Æ¦W: 19, »â°ì´Á¥Z¼Æ: 77, »â°ì±Æ¦W: 24.68%)

Inhibition of human prostate cancer cells proliferation by a selective alpha1-adrenoceptor antagonist labedipinedilol-A involves cell cycle arrest and apoptosis
Shu-Fen Liou, Hung-Hong Lin, Jyh-Chong Liang, Ing-Jun Chen, Jwu-Lai Yeh* - - 1 - Toxicology - TOXICOLOGY 2009;256(1-2):13-24
(IF: 3.241, Journal Ranking: 19, Number of Journals of this Field: 77, Ranking: 24.68%)

78

²Ä¤T¥N¶tÂ÷¤l«ú§Ü¾¯Zanidip¹ï¦åºÞ¥­·Æ¦Ùªº¥Íªø§í¨î§@¥Î
ªLªY¾ì,³¢¸q©¾,¸­¦Ë¨Ó* - - 0 - Formosa Journal of Clinical Pharmacy - 2009 17¨÷(2´Á):1-13­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Growth inhibitory effects of Zanidip, a third-generation calcium antagonist, on vascular smooth muscle cells
Hsin-Hua Lin, Yi-Chung Kuo, Jwu-Lai Yeh* - - 0 - Formosa Journal of Clinical Pharmacy - 2009;17(2):1-13
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

79

labedipinedilol-A§í¨î¤j¹«¸£¦åºÞ¥­·Æ¦Ù²Ó­M¹q¦ì¬ÛÃö©Ê L«¬¶tÂ÷¤l³q¹D²o¯A³J¥Õ¿E–¡C
§d¬±¨k,³¯¤ìÀs,À¹¥ô®¥,ªL©É§D,¸­¦Ë¨Ó,§d«T¤¯,³¯­^«T* - - 1 - Vascular Pharmacology - VASC PHARMACOL 2009 51¨÷(2-3´Á):65-71­¶
(IF: 4.62, »â°ì±Æ¦W: 26, »â°ì´Á¥Z¼Æ: 256, »â°ì±Æ¦W: 10.16%)

Inhibition of voltage-gated L-type calcium channels by labedipinedilol-A involves protein kinase C in rat cerebrovascular smooth muscle cells
Wu BN, Chen ML, Dai ZK, Lin YL, Yeh JL, Wu JR, Chen IJ - - 1 - Vascular Pharmacology - VASC PHARMACOL 2009;51(2-3):65-71
(IF: 4.62, Journal Ranking: 26, Number of Journals of this Field: 256, Ranking: 10.16%)

80

Isoeugenodilol§í¨î¦åºÞ¥­·Æ¦Ù²Ó­M¼W¥Í©M®ð²yÂX±i³N·s¥Í¤º¼h¸g¥ÑERK1/2¥h¬¡¤Æ§@¥Î
¸­¦Ë¨Ó*,¼B²Qªâ,±i¥É¯\,ªLªY¾ì,¼BÀé¾±,§d¬±¨k,³¯­^«T,§d«T¤¯* - - 1 - JOURNAL OF BIOMEDICAL SCIENCE - J BIOMED SCI 2008 15¨÷(3´Á):375-389­¶
(IF: 2.013, »â°ì±Æ¦W: 45, »â°ì´Á¥Z¼Æ: 82, »â°ì±Æ¦W: 54.88%)

Isoeugenodilol inhibits smooth muscle cell proliferation and neointimal thickening after balloon injury via inactivation of ERK1/2 pathway
Yeh JL*, Liou SF, Chang YP, Lin SW, Liu TS, Wu BN, Chen IJ, Wu JR* - - 1 - JOURNAL OF BIOMEDICAL SCIENCE - J BIOMED SCI 2008;15(3):375-389
(IF: 2.013, Journal Ranking: 45, Number of Journals of this Field: 82, Ranking: 54.88%)

81

Tc-99m (V) DMSA»P¤HÃþ¦å¼ß³J¥Õ½è§@¥Î¾÷Âध¬ã¨s
§õºÑªÚ*,¸­¦Ë¨Ó,ªô«n¬z,¼Bª÷©÷,§E©¯¥q,¤ý¬ü´f,¨H¥ßº~ - - 0 - Kaohsiung J Med Sci - 2008 24¨÷(1´Á):1-9­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

EVALUATION OF TC-99M (V) DMSA BINDING TO HUMAN PLASMA PROTEINS
Lee BF*, Yeh JL, Chiu NT, Liu GC, Yu HS, Wang MH, Shen LH. - - 0 - Kaohsiung J Med Sci - 2008;24(1):1-9
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

82

²Ä3¥N¤G²BÏìÔr«¬¶tÂ÷¤lªýÂ_¾¯Labedipinedilol-A¹ïouabain¤Þ°_¤ß«ß¤£¾ã¤§§@¥Î
±ç¦Ü¤¤,¶À¦w²»,§d«T¤¯,¼B²Qªâ,À¹¥ô¥\,³¯­^«T,¸­¦Ë¨Ó* - - 1 - Drug Development Research - DRUG DEVELOP RES 2008 69¨÷(1´Á):26-33­¶
(IF: 1.375, »â°ì±Æ¦W: 25, »â°ì´Á¥Z¼Æ: 40, »â°ì±Æ¦W: 62.50%)

Effects of labedipinedilol-A, third-generation dihydropyridine-type calcium blocker, on ouabain-induced arrhythmia
Liang J.C., Huang A.H., Wu J.R., Liou S.F., Dai Z.K., Chen I.J., Yeh J.L.* - - 1 - Drug Development Research - DRUG DEVELOP RES 2008;69(1):26-33
(IF: 1.375, Journal Ranking: 25, Number of Journals of this Field: 40, Ranking: 62.50%)

83

À³¥Î¦h¯¸°g§A­±¸Õ¡]MMI¡^¿ï¾Ü¾Ç¤h«áÂå¾Ç¨t¾Ç¥Í
¼B§J©ú*,·¨«³ÄÉ,¼B±Ó,¸­¦Ë¨Ó,¿à¬K¥Í,¶À«T¶¯ - - 0 - Âå¾Ç±Ð¨| - 2007 11¨÷(2´Á):116-129­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Using aMultiple Mini-interview Approach to Select Graduate Entry Medical Students
Keh-Min Liu*, Yi-Hsin Yang,Min Liu, Jwu-Lai Yeh, Chung-Sheng Lai, Chun-Hsiung Huang - - 0 - Âå¾Ç±Ð¨| - 2007;11(2):116-129
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

84

Effects of sildenafil on pulmonary hypertension and levels of ET-1, eNOS, and cGMP in aorta-banded rats
À¹¥ô®¥, ÃÓ´Ö¤ß, ½²§Ó¤¯, ©P¥@µØ, ªL¨Ø½@,¸­¦Ë¨Ó, ¾GÀ³¨D, ±i­«¸q, ³¯­^«T, §d«T¤¯* - - 1 - EXPERIMENTAL BIOLOGY AND MEDICINE - EXP BIOL MED 2006 231¨÷(6´Á):942-947­¶
(IF: 2.845, »â°ì±Æ¦W: 23, »â°ì´Á¥Z¼Æ: 76, »â°ì±Æ¦W: 30.26%)

Effects of sildenafil on pulmonary hypertension and levels of ET-1, eNOS, and cGMP in aorta-banded rats
Dai ZK, Tan MS, Chai CY, Chou SH, Lin PC, Yeh JL, Jeng AY, Chang CI, Chen IJ, Wu JR* - - 1 - EXPERIMENTAL BIOLOGY AND MEDICINE - EXP BIOL MED 2006;231(6):942-947
(IF: 2.845, Journal Ranking: 23, Number of Journals of this Field: 76, Ranking: 30.26%)

85

Differential change in expression of pulmonary ET-1 and eNOS in rats after chronic left ventricular pressure overload.
ÃÓ´Ö¤ß, ½²§Ó¤¯, §d«T¤¯, ¸­¦Ë¨Ó, ³¯­^«T, Ãö½JÄR, ¾GÀ³¨D, ·¨¼z§±, §õ©s¾±, À¹¥ô®¥* - - 1 - EXPERIMENTAL BIOLOGY AND MEDICINE - EXP BIOL MED 2006 231¨÷(6´Á):948-953­¶
(IF: 2.845, »â°ì±Æ¦W: 23, »â°ì´Á¥Z¼Æ: 76, »â°ì±Æ¦W: 30.26%)

Differential change in expression of pulmonary ET-1 and eNOS in rats after chronic left ventricular pressure overload.
Tan MS, Chai CY, Wu JR, Yeh JL, Chen IJ, Kwan AL, Jeng AY, Yang HY, Lee MH, Dai ZK* - - 1 - EXPERIMENTAL BIOLOGY AND MEDICINE - EXP BIOL MED 2006;231(6):948-953
(IF: 2.845, Journal Ranking: 23, Number of Journals of this Field: 76, Ranking: 30.26%)

86

¶ÀáIËï­l¥Íª«KMUP-1¤ÎKMUP-3§í¨î¤j¹«®ðºÞ«e,µoª¢ª«½èTNF-a¤Þµo»¤¾É«¬¤@®ñ¤Æ´á酶,Ãö³s©ó·»¸Ñ«¬³¾ÁTáIËïÀô¤Æ酶¤ÎG³J¥Õ¿E酶
§d¬±¨k, ³¯«Ø¤å,¼B²Qªâ, ¸­¦Ë¨Ó, Áé¼z¸© ,³¯­^«T* - - 1 - MOLECULAR PHARMACOLOGY - MOL PHARMACOL 2006 70¨÷(3´Á):977-985­¶
(IF: 4.469, »â°ì±Æ¦W: 26, »â°ì´Á¥Z¼Æ: 199, »â°ì±Æ¦W: 13.07%)

Inhibition of Proinflammatory Tumor Necrosis Factor--Induced Inducible Nitric-Oxide Synthase by Xanthine-Based 7-[2-[4- (2-Chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-Nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in Rat Trachea: The Involvement of Soluble Guanylate Cyclase and Protein Kinase G
Bin-Nan Wu, Chien-Wen Chen, Shu-Fen Liou, Jwu-Lai Yeh, Hui-Hsuan Chung, and Ing-Jun Chen* - - 1 - MOLECULAR PHARMACOLOGY - MOL PHARMACOL 2006;70(3):977-985
(IF: 4.469, Journal Ranking: 26, Number of Journals of this Field: 199, Ranking: 13.07%)

87

Protective effect of labedipinedilol-A, a novel dihydropyridine-type calcium channel blocker, on myoardial apoptosis in ischemia -- reperfusion injury.
±ç¦Ü¤¤, ³¯Îd»T,ªô»F°ò,¼B²Qªâ, ³¯­^«T,¸­¦Ë¨Ó* - - 1 - Life Sciences - LIFE SCI 2006 79¨÷(0´Á):1248-56­¶
(IF: 2.389, »â°ì±Æ¦W: 28, »â°ì´Á¥Z¼Æ: 76, »â°ì±Æ¦W: 36.84%)

Protective effect of labedipinedilol-A, a novel dihydropyridine-type calcium channel blocker, on myoardial apoptosis in ischemia -- reperfusion injury.
Liang JC, Chen HR, Chiu CC, Liou SF, Chen IJ, Yeh JL* - - 1 - Life Sciences - LIFE SCI 2006;79(0):1248-56
(IF: 2.389, Journal Ranking: 28, Number of Journals of this Field: 76, Ranking: 36.84%)

88

Liberadipinedilol-A¤§¦åºÞÃP¦¢§@¥Î¬ÛÃö¶tÂ÷¤l¤º¬y¤Þµo¤º¥Ö²Ó­M­l¥Í¤@®ñ¤Æ´á¤Î¨ä¦X¦¨酶ªí²{
¼B²Qªâ, §d«T¤¯ ,¿à¤å¼w, ³\³Ó¶¯, ³¯­^«T, ¸­¦Ë¨Ó* - - 1 - JOURNAL OF CARDIOVASCULAR PHARMACOLOGY - J CARDIOVASC PHARM 2005 45¨÷(3´Á):232-240­¶
(IF: 1.313, »â°ì±Æ¦W: 43, »â°ì´Á¥Z¼Æ: 72, »â°ì±Æ¦W: 59.72%)

The vasorelaxing action of labedipinedilol-A involves endothelial cell-derived NO and eNOS expression caused by calcium influx.
Liou SF, Wu JR , Lai WT, Sheu SH,Chen IJ, Yeh JL* - - 1 - JOURNAL OF CARDIOVASCULAR PHARMACOLOGY - J CARDIOVASC PHARM 2005;45(3):232-240
(IF: 1.313, Journal Ranking: 43, Number of Journals of this Field: 72, Ranking: 59.72%)

89

Åöíw»¤µo²Ó­M¤ºGABA A«¬¨üÅé°ï¿n
Goodkin HP*, ¸­¦Ë¨Ó, Kapur J - - 1 - JOURNAL OF NEUROSCIENCE - J NEUROSCI 2005 25¨÷(23´Á):5511-5520­¶
(IF: 7.506, »â°ì±Æ¦W: 14, »â°ì´Á¥Z¼Æ: 200, »â°ì±Æ¦W: 7.00%)

Status epilepticus increases the intracellular accumulation of GABA(A) receptors
Goodkin HP*, Yeh JL, Kapur J - - 1 - JOURNAL OF NEUROSCIENCE - J NEUROSCI 2005;25(23):5511-5520
(IF: 7.506, Journal Ranking: 14, Number of Journals of this Field: 200, Ranking: 7.00%)

90

Labedipinedilol C: ²Ä¤T¥Ndihydropyridine«¬¶tÂ÷¤l³q¹D«ú§Ü¾¯¡A§e²{¹[Â÷¤l³q¹D¶}±Ò¡B¤@®ñ¤Æ´á¬ÛÃö»PµÇ¤W¸¢«ú§Ü¬¡©Ê
¸­¦Ë¨Ó, ¼B²Qªâ, ±ç¦Ü¤¤, §õ»x¶¯, ªô»F°ò, ªL¥Ã­õ, ³¯­^«T* - - 1 - JOURNAL OF CARDIOVASCULAR PHARMACOLOGY - J CARDIOVASC PHARM 2005 46¨÷(2´Á):130-140­¶
(IF: 1.313, »â°ì±Æ¦W: 43, »â°ì´Á¥Z¼Æ: 72, »â°ì±Æ¦W: 59.72%)

Labedipinedilol-C: a third-generation dihydropyridine-type calcium channel antagonist displaying K+ channel opening, NO-dependent and adrenergic antagonist activities.
Yeh JL, Liou SF, Liang JC, Lee CH, Chiu CC, Lin YT, Chen IJ* - - 1 - JOURNAL OF CARDIOVASCULAR PHARMACOLOGY - J CARDIOVASC PHARM 2005;46(2):130-140
(IF: 1.313, Journal Ranking: 43, Number of Journals of this Field: 72, Ranking: 59.72%)

91

¦bÄ~µo©Ê¨ì¥ý¤Ñ©Ê¤ßŦ¯fªº¥®¨à»P¤p«Ä·|¼W¥[¦å²G´`Àôªº big endothelin-1¡Bendothelin-1¤Îatrial natriuretic peptide
¸­¦Ë¨Ó, ®}¥ò»¨, À¹¥ô¥\, ¼B²Qªâ, ³¯­^«T, §d«T¤¯* - - 1 - INTERNATIONAL JOURNAL OF CARDIOLOGY - INT J CARDIOL 2005 104¨÷(1´Á):15-20­¶
(IF: 1.765, »â°ì±Æ¦W: 32, »â°ì´Á¥Z¼Æ: 72, »â°ì±Æ¦W: 44.44%)

Increased circulating big endothelin-1, endothelin-1 and atrial natriuretic peptide in infants and children with heart failure secondary to congenital heart disease.
Yeh JL, Hsu JH, Dai ZK, Liou SF, Chen IJ, Wu JR* - - 1 - INTERNATIONAL JOURNAL OF CARDIOLOGY - INT J CARDIOL 2005;104(1):15-20
(IF: 1.765, Journal Ranking: 32, Number of Journals of this Field: 72, Ranking: 44.44%)

92

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®}¥ò»¨, ¸­¦Ë¨Ó, À¹¥ô®¥, ³¯Ãh¥Á, §d«T¤¯* - - 1 - INTERNATIONAL HEART JOURNAL - INT HEART J 2005 46¨÷(5´Á):867-875­¶
(IF: 0, »â°ì±Æ¦W: 72, »â°ì´Á¥Z¼Æ: 72, »â°ì±Æ¦W: 100.00%)

Increased circulating calcitonin gene-related peptide in congestive heart failure caused by congenital heart disease.
Hsu JH, Yeh JL, Dai ZK, Chen HM, Wu JR* - - 1 - INTERNATIONAL HEART JOURNAL - INT HEART J 2005;46(5):867-875
(IF: 0, Journal Ranking: 72, Number of Journals of this Field: 72, Ranking: 100.00%)

93

Vanylidilol: ¤@­f¤AîÇ°òµÇ¤W¸¢¯À¿E©Ê¥Ò/¤A«¬ªýÂ_¾¯¨ã¤º¥Ö²Ó­M¬ÛÃö»P¥ÒÂ÷¤l³q¹D¶}±Ò¬ÛÃöªº¦åºÞÃP¦¢¬¡©Ê¤§§Ü°ª¦åÀ£§@¥Î
ªô»F°ò,§d«T¤¯,§õ»x¶¯,¼B²Qªâ,À¹¥ô®¥,³¯­^«T,¸­¦Ë¨Ó* - - 1 - Pharmacology - PHARMACOLOGY 2004 70¨÷(3´Á):140-151­¶
(IF: 1.132, »â°ì±Æ¦W: 131, »â°ì´Á¥Z¼Æ: 186, »â°ì±Æ¦W: 70.43%)

Anti-Hypertension Effect of Vanylidilol: A Phenylaldehyde /-Adrenoceptor Blocker with Endothelium-Dependent and K+ Channels Opening-Associated Vasorelaxant Activities
Chaw-Chi Chiu, Jiunn-Ren Wu, Chih-Hsiung Lee, Shwu-Fen Liou, Zen-Kong Dai, Ing-Jun Chen, Jwu-Lai Yeh* - - 1 - Pharmacology - PHARMACOLOGY 2004;70(3):140-151
(IF: 1.132, Journal Ranking: 131, Number of Journals of this Field: 186, Ranking: 70.43%)

94

¤º¥Ö©Ê¤@®ñ¤Æ´á¦X¦¨»Ã¯À¤Î¤º¥Ö¯À-1¦b¤ß°IºÜ¤Þ°_ªºªÍ°ªÀ£ª¬ªp¤U¦³¤W¤ÉÁͶÕ
À¹¥ô®¥, ÃÓ´Ö¤ß, ½²§Ó¤¯, ¸­¦Ë¨Ó, ©P¥@µØ, ªô»F°ò, ¾GÀ³¨D,³¯­^«T, §d«T¤¯* - - 1 - Pediatric Pulmonology - PEDIATR PULM 2004 37¨÷(3´Á):249-256­¶
(IF: 1.662, »â°ì±Æ¦W: 15, »â°ì´Á¥Z¼Æ: 70, »â°ì±Æ¦W: 21.43%)

Upregulation of Endothelial Nitric Oxide Synthase and Endothelin-1 in Pulmonary Hypertension Secondary to Heart Failure in Aorta-Banded Rats
Zen-Kong Dai, Mian-Shin-Tan, Chee-Yin Chai, Jwu-Lai Yeh, Shah-Hwa Chou, Chaw-Chi Chiu, Arco Y. Jeng, Ing-Jun Chen and Jiunn-Ren Wu* - - 1 - Pediatric Pulmonology - PEDIATR PULM 2004;37(3):249-256
(IF: 1.662, Journal Ranking: 15, Number of Journals of this Field: 70, Ranking: 21.43%)

95

Labedipinedilol-A ¦b¤j¹«¥­·Æ¦Ù²Ó­M§í¨î¼W¥Í¬O¸g¥ÑPKC ©M ERK 1/2 ³~®|
¼B²Qªâ, ¸­¦Ë¨Ó, ±ç­P¤¤, ªô»F°ò, ªL¥Ã­õ, ³¯­^«T* - - 1 - J Cardiovasc Pharmacol - J CARDIOVASC PHARM 2004 44¨÷(5´Á):539-551­¶
(IF: 1.576, »â°ì±Æ¦W: 34, »â°ì´Á¥Z¼Æ: 71, »â°ì±Æ¦W: 47.89%)

Inhibition of Mitogen-Mediated Proliferation of Rat Vascular Smooth Muscle Cells by Labedipinedilol-A through PKC and ERK 1/2 Pathway
Shu-Fen Liou, Jwu-Lai Yeh, Jyh-Chong Liang, Chaw-Chi Chiu, Young-Tso Lin, Ing-Jun Chen - - 1 - J Cardiovasc Pharmacol - J CARDIOVASC PHARM 2004;44(5):539-551
(IF: 1.576, Journal Ranking: 34, Number of Journals of this Field: 71, Ranking: 47.89%)

96

µf´Ô´¹¯À­l¥Íª«VOA¸g¥ÑCGRP, NO, cGMP¤Î¦åºÞ¤º¥Ö¬ÛÃö§@¥Î¤Þ°_¤j¥Õ¹«¸zô½¤°Ê¯ß¤Î¥D°Ê¯ß¤§ÃP¦¢§@¥Î
ù©É­ë, ¿½´f®S, §dµn±j, ªLºa«Ï, ±ç¦Ü¤¤, ¸­¦Ë¨Ó, ³¯­^«T - - 1 - J Cardiovasc Pharmacol - J CARDIOVASC PHARM 2003 42¨÷(4´Á):511-520­¶
(IF: 1.905, »â°ì±Æ¦W: 27, »â°ì´Á¥Z¼Æ: 70, »â°ì±Æ¦W: 38.57%)

A novel capsaicin derivative VOA induced relaxation in rat mesenteric and aortic arteries: involvement of CGRP, NO, cGMP and endothelium-dependent activities
Yi-Ching Lo, Hui-Chuan Hsiao, Deng-Chyang Wu, Rong-Jyh Lin, Jhy-Chong Liang, Jwu-Lai Yeh, Ing-Jun Chen - - 1 - J Cardiovasc Pharmacol - J CARDIOVASC PHARM 2003;42(4):511-520
(IF: 1.905, Journal Ranking: 27, Number of Journals of this Field: 70, Ranking: 38.57%)

97

Pyrrolo-Benzylisoquinolineªº¦X¦¨¤Î§Ü¦å¤pªO¬¡©Ê±´°Q
³¢Ðz¯Ð, §d§Ó¤¤, ±iªÚºa, ¸­¦Ë¨Ó, ³¯­^«T, §d¥Ã©÷ - - 1 - Bioorganic & Medical Chemistry letters - 2003 13¨÷(5´Á):821-823­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Antiplatelet Activity of Synthetic Pyrrolo-benzylisoquinolines
140. Reen-Yen Kuo, Chin-Chung Wu, Fang-Rong Chang, Jwu-Lai Yeh, Ing-Jun Chen, and Yang-Chang Wu - - 1 - Bioorganic & Medical Chemistry letters - 2003;13(5):821-823
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

98

µf´Ô´¹¯À­l¥Íª«VOA¸g¥ÑCGRP, NO, cGMP¤Î¦åºÞ¤º¥Ö¬ÛÃö§@¥Î¤Þ°_¤j¥Õ¹«¸zô½¤°Ê¯ß¤Î¥D°Ê¯ß¤§ÃP¦¢§@¥Î
ù©É­ë, ¿½´f®S, §dµn±j, ªLºa«Ï, ±ç¦Ü¤¤, ¸­¦Ë¨Ó, ³¯­^«T - - 1 - J Cardiovasc Pharmacol - 2003 42¨÷(4´Á):511-520­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

A novel capsaicin derivative VOA induced relaxation in rat mesenteric and aortic arteries: involvement of CGRP, NO, cGMP and endothelium-dependent activities
Yi-Ching Lo, Hui-Chuan Hsiao, Deng-Chyang Wu, Rong-Jyh Lin, Jhy-Chong Liang, Jwu-Lai Yeh, Ing-Jun Chen - - 1 - J Cardiovasc Pharmacol - 2003;42(4):511-520
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

99

Labedipinedilol-A ¹ï©óDOCA-Salt ¤j¹«¤ß«Ç©ÊPKC- ¤Î¤º¤Àªc©Ê°T®§¤§¼vÅT
¸­¦Ë¨Ó, ±ç¦Ü¤¤, ¼B²Qªâ, ªL¥Ã­õ, ³\³Ó¶¯, ¿à¤å¼w, ¨¯¿ü³¹, ³¯­^«T - - 1 - DRUG DEVELOPMENT RESEARCH - 2003 59¨÷(3´Á):307-315­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Ventricular PKC- and humoral signaling in DOCA-Salt rats treated with labedipinedilol-A
Jwu-Lai Yeh 1, Jyh-Chong Liang 1, Shwu-Fen Liou 1, Young-Tso Lin 2, Sheng-Hsiung Sheu 3, Wen-Ter Lai 3, Shyi-Jang Shin 3, Ing-Jun Chen 1 * - - 1 - DRUG DEVELOPMENT RESEARCH - 2003;59(3):307-315
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

100

Labedipinedilol-A ¹ï©óDOCA-Salt¤j¹«¤ß«Ç©ÊPKC-¤Î¤º¤Àªc©Ê°T®§¤§¼vÅT
¸­¦Ë¨Ó,±ç¦Ü¤¤,¼B²Qªâ,ªL¥Ã­õ,³,³Ó¶¯,¿à¤å¼w,¨¯¿ü³¹,³¯­^«T - - 1 - Drug Development Research - 2003 59¨÷(3´Á):307-315­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Ventricular PKC-e and Humoral Signaling in DOCA-Salt Rats Treated with Labedipinedilol-A
Jwu-Lai Yeh, Jyh-Chong Liang, Shwu-Fen Liou, Young-Tso Lin, Sheng-Hsiung Sheu, Wen-Ter Lai, Shi-Jang Shin, and Ing-Jun Chen - - 1 - Drug Development Research - 2003;59(3):307-315
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

101

·s¤@¥N¨ã¦³4-Phenyl Oxypropanolamineªº¤G²BÎMÔr«¬¶tÂ÷¤l³q¹DªýÂ_¾¯§e²{µÇ¤W¸¢¥Ò/¤A«¬¨üÅé«ú§Ü¤Îªø´Á§Ü°ª¦åÀ£ªº ¬¡©Ê
±ç¦Ü¤¤,¸­¦Ë¨Ó,¤ý¹ÅÁJ,¼B²Qªâ,½²Ík©M,³¯­^«T - - 1 - Bioorganic & Medicinal Chemistry - 2002 10¨÷(3´Á):719-730­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

The New Generation Dihydropyridine Type Calcium Blockers, Bearing 4-Phenyl Oxypropanolamine, Display alpha-/beta-Adrenoceptor Antagonist and Long Acting Antihypertensive Activities
Jhy-Chong Liang, Jwu-Lai Yeh, Chia-Sui Wang, Shwu-Fen Liou, Chieh-Ho Tsai, Ing-Jun Chen* - - 1 - Bioorganic & Medicinal Chemistry - 2002;10(3):719-730
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

102

¥ÑHernandia nymphaeifolia ¯Â¤Æ¤§lignans¹ïµÇ¤pºÞ²Ó­M¤º¶tÂ÷¤l¤§§@¥Î±´°Q
»¯¥É­^, ³¯¯qª@, ¸­¦Ë¨Ó, µ¥¤H - - 1 - European Journal of Pharmacology - 2002 433¨÷(1´Á):31-38­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Novel action of lignans isolated from Hernandia nymphaeifoliaon Ca2+ signaling in renal tubular cells
Yu-Ying Chao, Ih-Sheng Chen, Jwu-Lai Yeh, et al - - 1 - European Journal of Pharmacology - 2002;433(1):31-38
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

103

­»§¨ÄõÓi¬°°©¬[ªº¤þ¾JÓi­l¥Íª«¨ã¦³µÇ¤W¸¢¯À¥Ò/¤A«¬¨üÅéªýÂ_©M¦åºÞÃP¦¢¯S©Ê
¸­¦Ë¨Ó,§d«T¤¯,ªô»F°ò,³¯¶®ª³,ù©É­ë,ªL¥Ã­õ,¾G¹ü¬F,³¯­^«T* - - 1 - Journal of Cardiovascular Pharmacology - 2002 39¨÷(6´Á):´Á 803-813 ­¶­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

A Vanillylamide-Based Propanolamine Derivative Displays alpha/beta-Adrenoceptor Blocking and Vasodilating Properties
Jwu-Lai Yeh, Jiunn-Ren Wu, Chaw-Chi Chiu, Yea-Wen Chen, Yi-Ching Lo, Young-Tso Lin, Chang-Jenq Cheng, Ing-Jun Chen* - - 1 - Journal of Cardiovascular Pharmacology - 2002;39(6):´Á 803-813 ­¶
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

104

KMUP 880708:¤@ºØ¥Hvanillylamide¬[ºcµÇ¤W¸¢¤A¤@«¬¨üÅé«ú§Ü¾¯¨ã¦³¥Ò«¬¨üÅéªýÂ_¤Î¹[Â÷¤l³q¹D¶}±Ò¬¡©Ê
ªô»F°ò,³¯¶®ª³,§d«T¤¯,ªL¥Ã­õ,³¯­^«T,¸­¦Ë¨Ó* - - 1 - Drug Development Research - 2002 55¨÷(2´Á):104-117­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

KMUP 880708: A Vanyllilamide-Based beta1-Adrenoceptor Antagonist With alpha-Adrenoceptor Blocking and Potassium Channel Opening Activities
KMUP 880708: A Vanyllilamide-Based beta1-Adrenoceptor Antagonist with alpha-Arenoceptor Blocking and Potassium Channel Opening Activities - - 1 - Drug Development Research - 2002;55(2):104-117
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

105

­»§¨ÄõÓi¬°°©¬[ªº¤þ¾JÓi­l¥Íª«¨ã¦³µÇ¤W¸¢¯À¥Ò/¤A«¬¨üÅéªýÂ_©M¦åºÞÃP¦¢¯S©Ê
¸­¦Ë¨Ó,§d«T¤¯,ªô»F°ò,³¯¶®ª³,ù©É­ë,ªL¥Ã­õ,¾G¹ü¬F,³¯­^«T* - - 1 - Journal of Cardiovascular Pharmacology - 2002 39¨÷(6´Á):803-813­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

A Vanillylamide-Based Propanolamine Derivative Displays alpha/beta-Adrenoceptor Blocking and Vasodilating Properties
Jwu-Lai Yeh, Jiunn-Ren Wu, Chaw-Chi Chiu, Yea-Wen Chen, Yi-Ching Lo, Young-Tso Lin, Chang-Jenq Cheng, Ing-Jun Chen* - - 1 - Journal of Cardiovascular Pharmacology - 2002;39(6):803-813
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

106

¥H¦å¼ß¤¤§¿µµ½è¿Ã¥úÀË´ú»²§U¶EÂ_¤Î°l(9e53)¿ðµo©Ê¥Ö½§µµ½è¯f
«J·½¸Î, ³,´¸­õ, ¤ý»ÊÀé, ¸­¦Ë¨Ó, §E©¯¥q - - 0 - Dermatol Sin - 2001 19¨÷(0´Á):316-323­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Detection of plasma uroporphyrin fluorescence as an adjuvant diagnostic and follow-up tool of porphyria cutanea tarda.
Yuan-Yue Hou, Roger Chin-Che Hsu, Ming-Tsan Wang, Jwu-Lai Yeh, Hsin-Su Yu - - 0 - Dermatol Sin - 2001;19(0):316-323
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

107

²Ä¤T¥N¤G²BÏìÔr«¬¶tÂ÷¤lªýÂ_¾¯ Labedipinedilol-B ¨ã¦³¥Ò/¤A«¬µÇ¤W¸¢¿E©ÊªýÂ_¬¡©Ê
¸­¦Ë¨Ó,½²Ík©M,±ç¦Ü¤¤,§d«T¤¯,¶À¤¹§Ó,³¯­^«T - - 1 - Drug Development Research - 2001 52¨÷(3´Á):462-474­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

The Third Generation Dihydropyridine Type Calcium Channel Blocker Labedipinedilol-B displaying £\/£]-Adrenoceptor Blocking Activities
Jwu-Lai Yeh, Chieh-Ho Tsai, Jhy-Chong Liang, Jiunn-Ren Wu,Yeun-Chih Huang and Ing-Jun Chen* - - 1 - Drug Development Research - 2001;52(3):462-474
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

108

²Ä¤T¥N¤G²BÏìÔr«¬¶tÂ÷¤lªýÂ_¾¯ Labedipinedilol-B ¨ã¦³¥Ò/¤A«¬µÇ¤W¸¢¿E©ÊªýÂ_¬¡©Ê
¸­¦Ë¨Ó,½²Ík©M,±ç¦Ü¤¤,§d«T¤¯,¶À¤¹§Ó,³¯­^«T - - 1 - Drug Development Research - 2001 52¨÷(3´Á):462-474­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

The Third Generation Dihydropyridine Type Calcium Channel Blocker Labedipinedilol-B displaying £\/£]-Adrenoceptor Blocking Activities
Jwu-Lai Yeh, Chieh-Ho Tsai, Jhy-Chong Liang, Jiunn-Ren Wu,Yeun-Chih Huang and Ing-Jun Chen - - 1 - Drug Development Research - 2001;52(3):462-474
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

109

Vanidipinedilol: ¤@­Ó¥HVanilloid¬°°©¬[¥B¨ã¦³ªýÂ_¶tÂ÷¤l³q¹D¤Î¦åºÞÂX±i¬¡©Ê¤§¤A«¬µÇ¤W¸¢¯À©Ê¨üÅéªýÂ_¾¯
¸­¦Ë¨Ó,¼B²Qªâ,±ç¦Ü¤¤,¶À¤¹§Ó,½±³s°],§d«T¤¯,ªL¥Ã­õ,³¯­^«T - - 1 - J. Cardiovascular Pharmacology - 2000 35¨÷(0´Á):51-63­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Vanidipinedilol: A Vanilloid-Based beta-Adrenoceptor Blocker Displaying Calcium Entry Blocking and Vasorelaxant Activities
Jwu-Lai Yeh, Shwu-Fen Liou, Jyh-Chong Liang, Yeun-Chih Huang,Lien-Chai Chiang, Jiunn-Ren Wu, Young-Tso Lin and Ing-Jun Chen - - 1 - J. Cardiovascular Pharmacology - 2000;35(0):51-63
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

110

¤@­ÓîÇ°ò«¬¥Ò/¤A«¬µÇ¤W¸¢¨üÅéªýÂ_¾¯¨ã¦³¦åºÞÃP¦¢¯S©Ê¤§ÃIJz§@¥Î
ªô»F°ò,ªL¥Ã­õ,½²Ík©M,±ç¦Ü¤¤,½±³s°],§d«T¤¯,³¯­^«T,¸­¦Ë¨Ó* - - 1 - General Pharmacology - 2000 34¨÷(6´Á):391-400­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Pharmacological effects of an aldehyde type /-adrenoceptor blocking agent with vasodilating properties
Chaw-Chi Chiu, Young-Tso Lin, Chieh-Ho Tsai, Jhy-Chong Liang, Lien-Chai Chiang, Jiunn-Ren Wu, Ing-Jun Chen, Jwu-Lai Yeh - - 1 - General Pharmacology - 2000;34(6):391-400
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

111

Labedipinedilol-A:¤@­Ó¥HVanilloid¬°°©¬[¨Ã¨ã¦³¶tÂ÷¤l³q¹DªýÂ_¤Îªø®Ä©Ê§Ü°ª¦åÀ£¯S©Ê¤§µÇ¤W¸¢¯À©Ê¥Ò/¤A«¬¨üÅéªýÂ_¾¯
±ç¦Ü¤¤,¸­¦Ë¨Ó,½±³s°],·¨¥É¼b,³,³Ó¶¯,¿à¤å¼w,³¯­^«T - - 1 - Drug development reseach - 2000 49¨÷(0´Á):94-108­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Labedipinedilol-A: A Vanilloid-Based alpha/beta-Adrenoceptor Blocker With Calcium Entry Blocking and Long Acting Anti-hypertensive Properties
Jhy-Chong Liang, Jwu-Lai Yeh, Lien-Chai Chiang, Yu-Chiao Yang , Sheng-Hsiung Sheu, Wen-Ter Lai and Ing-Jun Chen - - 1 - Drug development reseach - 2000;49(0):94-108
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

112

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ªô»F°ò,ªL¥Ã­õ,½²Ík©M,±ç¦Ü¤¤,½±³s°],§d«T¤¯,³¯­^«T,¸­¦Ë¨Ó - - 1 - General Pharmacology - 2000 34¨÷(6´Á):391-400­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Pharmacological effects of an aldehyde type/-adrenoceptor blocking agent with vasodilating properties
Chaw-Chi Chiu, Young-Tso Lin, Chieh-Ho Tsai, Jhy-Chong Liang, Lien-Chai Ching, Jiunn-Ren Wu, Ing-Jun Chen, Jwu-Lai Yeh - - 1 - General Pharmacology - 2000;34(6):391-400
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

113

¹[Â÷¤l¬ÛÃöÃĪ«¹ïà®201¶i¤J¥®¹«¤ß¦Ù°ö¾i²Ó­Mªº¼vÅT--ªì¨B³ø§i
³¯·¶¶², ¸­¦Ë¨Ó, ¶À¤¹§Ó, ³¯­^«T, ¶À­^®p, ¼Bª÷©÷ - - 0 - °ª¶¯Âå¾Ç¬ì¾ÇÂø»x - 2000 0¨÷(0´Á):134-140­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

The interference of uptake of thallium 201 in cultured rat myocardial cells with existence of potassium related pharmaceuticals - A prelliminary report.
Chen YW, Yeh JL, Huang YC, Chen JJ, Huang YF and Liu GC. - - 0 - °ª¶¯Âå¾Ç¬ì¾ÇÂø»x - 2000;0(0):134-140
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

114

¤@­ÓîÇ°ò«¬¥Ò/¤A«¬µÇ¤W¸¢¨üÅéªýÂ_¾¯¨ã¦³¦åºÞÃP¦¢¯S©Ê¤§ÃIJz§@¥Î
ªô»F°ò,ªL¥Ã­õ, ½²Ík©M, ±ç¦Ü¤¤, ½±³s°], §d«T¤¯, ³¯­^«T, ¸­¦Ë¨Ó - - 1 - General Pharmacology - 2000 34¨÷(6´Á):391-400­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Pharmacological effects of an aldehyde typw/-adrenoceptor blocking agent with vasodilating properties
Chaw-Chi Chiu, Young-Tso Lin, Chieh-Ho Tsai, Jhy-Chong Liang, Lien-Chai Chiang, Jiunn-Ren Wu, Ing-Jun Chen, Jwu-Lai Yeh - - 1 - General Pharmacology - 2000;34(6):391-400
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

115

Ferulidilol:­Ý¨ã¦³¤A¤G«¬µÇ¤W¸¢¿E©Ê­P®Ä¾¯§@¥Î¤§¦åºÞÃP¦¢¤Î§Ü®ñ¤Æ§@¥Î¤§µÇ¤W¸¢¿E©Ê¤Î¶tÂ÷¤l³q¹DªýÂ_¾¯
¶À¤¹§Ó,¸­¦Ë¨Ó,§d¬±¨k,ù©É­ë,±ç¦Ü¤¤,ªL¥Ã­õ,³,³Ó¥ú,³¯­^«T - - 1 - Drug Development Research - 1999 47¨÷(0´Á):77-89­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Ferulidilol: A vasodilatory and antioxidant adrenoceptor and calcium entry blocker, with ancillary b2-agonist activity
Yeun-Chih Huang, Jwu-Lai Yeh, Bin-Nan Wu, Yi-Ching Lo, Jhy-Chong Liang, Young-Tso Lin, Sheng-Hsiung Sheu, and Ing-Jun Chen - - 1 - Drug Development Research - 1999;47(0):77-89
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

116

µv°ò¤Æ¿»´Ô´¹¯À­«·s¦Ò¶q²B½è¤l»Ä©ó¿»´Ô´¹¯À»¤µo¤§·Pı¯«¸g¬¡©Ê¤§¨¤¦â
·¨¥É¼b,°¨¨ä·ç,¸­¦Ë¨Ó,ù©É­ë,§d¬±¨k,ªL¥Ã­õ,³¯­^«T - - 1 - General Pharmacology - 1999 33¨÷(0´Á):257-269­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

Nitrated nonivamide displaying a drawback of proton¡¦s role in capsaicin associated sensory and neuronal activities
Yu-Chiao Yang, Chyi-Ruei Ma, Jwu-Lai Yeh, Yi-Ching Lo, Bin-Nan Wu, Young-Tso Lin, and Ing-Jun Chen - - 1 - General Pharmacology - 1999;33(0):257-269
(IF: , Journal Ranking: , Number of Journals of this Field: , Ranking: %)

117

Ionic effects of capsinolol, a calcitonin gene-related peptide releasing b-adrenoceptor blocker, on isolated cardiac muscle
¸­¦Ë¨Ó,§d«T¤¯,ªL¥¿¤@,³¯­^«T - - 1 - General Pharmacology - 1998 31¨÷(2´Á):253-260­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

118

Capsazocaine : a capsaicin-sensitivity functional antagonist displays an argument on sensory capsaicin receptor
³¯­^«T,ù©É­ë,ù°û­s,¸­¦Ë¨Ó,§d¬±¨k - - 1 - Gen. Pharmacol. - 1997 29¨÷(3´Á):387-395­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

«Ý¸É
«Ý¸É - - 1 - Gen. Pharmacol. - 1997;29(3):387-395
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

119

Capsinolol: the first £]-adrenoceptor blocker with an associated calcitonin gene-related peptide releasing activity in the heart
³¯­^«T,¸­¦Ë¨Ó,ù©É­ë,³,³Ó¶¯,ªL¥Ã­õ - - 1 - British Journal of Pharmacology - 1997 119¨÷(0´Á):7-14­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

120

Comparative study on the pharmacokinetic bioequivalence of two intravascular ceftriazone preparations
¶À°ª±l,·¨¦Ë­Z,§d¬±¨k,¸­¦Ë¨Ó,·¨¥Ã¹F,¹Ø²QªÚ,³¯­^«T - - 0 - Journal of Food and Drug Analysis - 1997 5¨÷(1´Á):51-56­¶
(IF: , »â°ì±Æ¦W: , »â°ì´Á¥Z¼Æ: , »â°ì±Æ¦W: %)

 Project

NO
YEAR ¡X Source ¡X No ¡X Type
Project Name
Duration
1
114 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSTC112-2320-B-037-019-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¸É°©¯×¹ç¥Î©ó¤ú©Pª¢©M°±¸g«á°©½è²¨ÃPÅj¾¦°Êª«¼Ò«¬¹ïµoª¢©Ê°©·lÃa©M»k°©²Ó­M¹L«×¬¡¤Æ¤§ªvÀø¾¯(3/3)( )
2025/08/01 ~ 2026/07/31
2
113 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSTC112-2320-B-037-019-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¸É°©¯×¹ç¥Î©ó¤ú©Pª¢©M°±¸g«á°©½è²¨ÃPÅj¾¦°Êª«¼Ò«¬¹ïµoª¢©Ê°©·lÃa©M»k°©²Ó­M¹L«×¬¡¤Æ¤§ªvÀø¾¯(2/3)( )
2024/08/01 ~ 2026/07/31
3
113 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X NSTC113-2811-B-037-008 ¡X 9 ³Õ¤h«á¬ã¨s­û
³Õ¤h¯Å¬ã¨s¤H­û--¶À¤W®¦( )
2024/08/01 ~ 2025/07/31
4
112 ¡X DK «e¤­«ÂI(­ì®Õ°|) ¡X KMU-DK(A)113001 ¡X  
¥Ì¯ó¯À­l¥Íª«ªº§Üµoª¢©M§Ü»k°©²Ó­M·s¥Í§@¥Î¥i´î½w¹êÅç©Ê¤ú©Pª¢¤§¬ã¨s( )
2024/01/01 ~ 2024/12/31
5
112 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSTC112-2320-B-037-019-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¸É°©¯×¹ç¥Î©ó¤ú©Pª¢©M°±¸g«á°©½è²¨ÃPÅj¾¦°Êª«¼Ò«¬¹ïµoª¢©Ê°©·lÃa©M»k°©²Ó­M¹L«×¬¡¤Æ¤§ªvÀø¾¯(1/3)( )
2023/08/01 ~ 2026/07/31
6
112 ¡X X °ª©_¦X§@­pµe ¡X 113CM-KMU-09 ¡X  
±´°Q¶À»G×ô©M¨~ªG苷¥Î©óµÇ°IºÜ¤Þ°_¤§°Ê¯ßµ°ª¬µw¤Æ¤j¹«ªºªvÀø®ÄªG( )
2024/08/01 ~ 2025/07/31
7
112 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X NSTC112-2811-B-037-006 ¡X 9 ³Õ¤h«á¬ã¨s­û
³Õ¤h¯Å¬ã¨s¤H­û--¶À¤W®¦( )
2023/08/01 ~ 2024/07/31
8
112 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X NSTC113-2813-C-037-078-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
113¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-Áú©û¿o(Âå¾Ç2)( )
2024/07/01 ~ 2025/02/28
9
111 ¡X DK «e¤­«ÂI(­ì®Õ°|) ¡X KMU-DK(A)112010 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«´î½w¹êÅç©ÊÃö¸`ª¢ªº¤À¤l¾÷Âà¬ã¨s( )
2023/01/01 ~ 2023/12/31
10
111 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X MOST109-2320-B-037-024-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«§í¨î¯}°©²Ó­M¥Í¦¨©M¤ú©Pª¢¤Þ°_ªº¤ú¼Ñ°©¯}ÃaªºªvÀø¾÷Âà(3/3)( )
2022/08/01 ~ 2023/07/31
11
111 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X NSTC112-2813-C-037-059-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
112¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-¹ùͺ´ü(Å@²z3)( )
2023/07/01 ~ 2024/02/29
12
110 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X MOST109-2320-B-037-024-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«§í¨î¯}°©²Ó­M¥Í¦¨©M¤ú©Pª¢¤Þ°_ªº¤ú¼Ñ°©¯}ÃaªºªvÀø¾÷Âà(2/3)( )
2021/08/01 ~ 2023/07/31
13
110 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X MOST111-2813-C-037-062-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
111¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-ªLªÛ¼Ö(Âå¾Ç2)( )
2022/07/01 ~ 2023/02/28
14
109 ¡X DK «e¤­«ÂI(­ì®Õ°|) ¡X KMU-DK(A)110002 ¡X  
±´°Qºd¤¯²y³J¥Õ´î½w¦åºÞ¶t¤Æ¯fÅܪº«OÅ@¾÷Âà( )
2021/01/01 ~ 2021/12/31
15
109 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X MOST109-2320-B-037-024-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«§í¨î¯}°©²Ó­M¥Í¦¨©M¤ú©Pª¢¤Þ°_ªº¤ú¼Ñ°©¯}ÃaªºªvÀø¾÷Âà(1/3)( )
2020/08/01 ~ 2023/07/31
16
108 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X MOST106-2320-B-037-010-MY3 ¡X 1 ­Ó¤H«¬
¶ÀÍÁ¯À¤ÎÃþ¦üª«¹ï¸¡¥D°Ê¯ß½F©Mµ°ª¬°Ê¯ßµw¤Æ½Õ¸`²É¸¢Åé°ÊºA©M¦Û¾½§@¥Îªº¾÷Âà±´°Q(3/3)( )
2019/08/01 ~ 2020/07/31
17
108 ¡X X °ª©_¦X§@­pµe ¡X 109CM-KMU-11 ¡X  
±´°Q¶ÀÍÁ¯À¹ï©óºû¥Í¯ÀD3¥[¥§¥j¤B¤Þ°_¤ß¦åºÞ¶t¤Æªº«OÅ@¾÷Âà( )
2020/05/01 ~ 2021/04/30
18
108 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X MOST109-2813-C-037-019-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
109¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-³¯¤ªªé(Âå¾Ç2)( )
2020/07/01 ~ 2021/02/28
19
107 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X MOST106-2320-B-037-010-MY3 ¡X 1 ­Ó¤H«¬
¶ÀÍÁ¯À¤ÎÃþ¦üª«¹ï¸¡¥D°Ê¯ß½F©Mµ°ª¬°Ê¯ßµw¤Æ½Õ¸`²É¸¢Åé°ÊºA©M¦Û¾½§@¥Îªº¾÷Âà±´°Q(2/3)( )
2018/08/01 ~ 2020/07/31
20
107 ¡X Y °ªÂå-¹ü°ò¦X§@­pµe ¡X 108-CCH-KMU-009 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«½w¸Ñ¤ßŦ¯Ê¦å©Ò²£¥Íªº¤ßŦ²Ó­M­ä¤`¤§¬ã¨s( )
2019/01/01 ~ 2019/12/31
21
106 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X MOST106-2320-B-037-010-MY3 ¡X 1 ­Ó¤H«¬
¶ÀÍÁ¯À¤ÎÃþ¦üª«¹ï¸¡¥D°Ê¯ß½F©Mµ°ª¬°Ê¯ßµw¤Æ½Õ¸`²É¸¢Åé°ÊºA©M¦Û¾½§@¥Îªº¾÷Âà±´°Q(1/3)( )
2017/08/01 ~ 2020/07/31
22
105 ¡X Z ¤j±M¾Ç¥Í¬ã¨s­pµe¤Î³Õ¤h«á ¡X MOST106-2813-C-037-023-B ¡X 8 ¤j±M¾Ç¥Í¬ã¨s­pµe
106¦~«×¤j±M¾Ç¥Í¬ã¨s­pµe-±i¤¨ºö(¥Í§Þ3)( )
2017/07/01 ~ 2018/02/28
23
104 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC102-2320-B-037-028-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«»¤¾É¤ß¦Ù²Ó­M¦ÛÅé§]¾½¦æ¬°¤§¤ßŦ«OÅ@¾÷Âà(3/3)( )
2015/08/01 ~ 2016/07/31
24
104 ¡X TP ³»¦y­pµe(°ªÂå) ¡X KMU-TP104PR03 ¡X  
±´°Q³F´ß¯ó¡B¨®®á¤l©M¥Õ­TµÑ¨úª«½Æ¤è¤§§Ü°ª¦åÀ£¤Î¤ßŦ«OÅ@§@¥Î¾÷Âà( )
2015/11/01 ~ 2016/09/30
25
104 ¡X X °ª©_¦X§@­pµe ¡X 105CM-KMU-07 ¡X  
±´°Q¶ÀÍÁ¯À§í¨î¦åºÞ¦¬ÁY¯ÀII»¤¾É¸¡¥D°Ê¯ß½Fªº¤À¤l¾÷Âà( )
2016/05/01 ~ 2017/04/30
26
103 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC102-2320-B-037-028-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«»¤¾É¤ß¦Ù²Ó­M¦ÛÅé§]¾½¦æ¬°¤§¤ßŦ«OÅ@¾÷Âà(2/3)( )
2014/08/01 ~ 2016/07/31
27
103 ¡X X °ª©_¦X§@­pµe ¡X 104CMKMU010 ¡X  
±´°Q²Ó­M¥~¼öªL§J³J¥Õ§í¨î¥Ñ¯×¦hÁÞÅé¨ë¿E¤§¥¨¾½²Ó­Mµoª¢¤ÏÀ³ªº§@¥Î¾÷Âà( )
2015/05/01 ~ 2016/04/30
28
102 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC102-2320-B-037-028-MY3 ¡X 1 ­Ó¤H«¬
±´°Q¯ùÆP­l¥Íª«»¤¾É¤ß¦Ù²Ó­M¦ÛÅé§]¾½¦æ¬°¤§¤ßŦ«OÅ@¾÷Âà(1/3)( )
2013/08/01 ~ 2016/07/31
29
101 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC99-2320-B-037-015-MY3 ¡X 1 ­Ó¤H«¬
±´°QÁC»Ä¤Gà­酶§í¨î¾¯¹ï»k°©²Ó­M·s¥Í§@¥Î¤§¤À¤l½Õ±±¾÷¨î(3/3)( )
2012/08/01 ~ 2013/07/31
30
100 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC99-2320-B-037-015-MY3 ¡X 1 ­Ó¤H«¬
±´°QÁC»Ä¤Gà­酶§í¨î¾¯¹ï»k°©²Ó­M·s¥Í§@¥Î¤§¤À¤l½Õ±±¾÷¨î(2/3)( )
2011/08/01 ~ 2013/07/31
31
099 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC99-2320-B-037-015-MY3 ¡X 1 ­Ó¤H«¬
±´°QÁC»Ä¤Gà­酶§í¨î¾¯¹ï»k°©²Ó­M·s¥Í§@¥Î¤§¤À¤l½Õ±±¾÷¨î(1/3)( )
2010/08/01 ~ 2013/07/31
32
098 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC96-2628-B-037-008-MY3 ¡X 1 ­Ó¤H«¬
±´°QRho-kinase§í¨î¾¯¦b¤ß¦Ù±ð¶ë©M¦åºÞµjÅ˩ʤߵ±µh¼Ò¦¡ªº²Ó­M«OÅ@¾÷Âà(3/3)( )
2009/08/01 ~ 2010/07/31
33
097 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC96-2628-B-037-008-MY3 ¡X 1 ­Ó¤H«¬
±´°QRho-kinase§í¨î¾¯¦b¤ß¦Ù±ð¶ë©M¦åºÞµjÅ˩ʤߵ±µh¼Ò¦¡ªº²Ó­M«OÅ@¾÷Âà(2/3)( )
2008/08/01 ~ 2010/07/31
34
096 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC96-2628-B-037-008-MY3 ¡X 1 ­Ó¤H«¬
±´°QRho-kinase§í¨î¾¯¦b¤ß¦Ù±ð¶ë©M¦åºÞµjÅ˩ʤߵ±µh¼Ò¦¡ªº²Ó­M«OÅ@¾÷Âà(1/3)( )
2007/08/01 ~ 2010/07/31
35
095 ¡X C ¤¤ÂåÃÄ ¡X CCMP 96-RD-014 ¡X 1 ­Ó¤H«¬
¤T¶ÀÂm¤ß´ö¹ï¤ßŦ¯Ê¦å¦AÄé¬y¶Ë®`°Êª«¼Ò¦¡¤§Àø®Äµû¦ô( )
2007/05/01 ~ 2008/04/30
36
095 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC95-2320-B-037-041- ¡X 1 ­Ó¤H«¬
±´°Q²Ä¤T¥NÎMÔr«¬¶tÂ÷¤lªýÂ_¾¯§Ü®ñ¤Æ§C±K«×¯×³J¥Õ¤Þ°_¶Ë®`¤§¨¾¤î°Ê¯ßµ°ª¬µw¤Æ§@¥Î( )
2006/08/01 ~ 2007/07/31
37
094 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC94-2320-B-037-042- ¡X 1 ­Ó¤H«¬
±´°QÎMÔr«¬¶tÂ÷¤l³q¹DªýÂ_¾¯§í¨î¦åºÞ·l¶Ë«á¤º¼h¼W¥Í²{¶H¤§¦åºÞ«OÅ@¾÷Âà( )
2005/08/01 ~ 2006/07/31
38
093 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC93-2320-B-037-036- ¡X 1 ­Ó¤H«¬
±´°QÎMÔr«¬¶tÂ÷¤lªýÂ_¾¯§Ü¤º¥Ö²Ó­M®ñ¤Æ¶Ë®`¤§¦åºÞ«OÅ@§@¥Î( )
2004/08/01 ~ 2005/07/31
39
092 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC92-2320-B-037-024- ¡X 1 ­Ó¤H«¬
²Ä¤T¥NÎMÔr«¬¶tÂ÷¤l³q¹DªýÂ_¾¯¦b¦åºÞ¥­·Æ¦Ù¤Î¤º¥Ö²Ó­M¤§¦åºÞ«OÅ@§@¥Î¾÷Âà±´°Q( )
2003/08/01 ~ 2004/07/31
40
091 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC91-2320-B-037-062 ¡X 1 ­Ó¤H«¬
²Ä¤T¥NÎMÔr«¬¶tÂ÷¤l³q¹DªýÂ_¾¯§Ü¯Ê¦å¦AÄé¬y¶Ë®`¤§¤À¤l¾÷Âà±´°Q( )
2002/08/01 ~ 2003/07/31
41
090 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC90-2315-B-037-001 ¡X 1 ­Ó¤H«¬
±´°Q²Ä¤T¥NÎMÔr«¬¶tÂ÷¤l³q¹DªýÂ_¾¯¹ï¤ßŦ¯Ê¦å¦AÄé¬y¶Ë®`¤§«OÅ@§@¥Î(Cardiopective effect of the third generation dihydropy-ridine type calcium chennel blockers on myocardial ischemia/reperfusion in jury)
2001/08/01 ~ 2002/07/31
42
089 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC 89-2320-B-037-082- ¡X 1 ­Ó¤H«¬
¨ã¹[³q¹D§í¨î©Ê½èªºµÇ¤W¸¢¯À©Ê¨üÅé¥Ò/¤A«¬ªýÂ_¾¯¤§ÃIJz±´°Q(Pharmacological approach of novel type alpha/beta-adrenocep-tor blocker with potassium channel blocking properties)
2000/08/01 ~ 2001/07/31
43
088 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC 89-2320-B-037-003- ¡X 1 ­Ó¤H«¬
¨ã¹[³q¹D§í¨î©Ê½èªºµÇ¤W¸¢¯À©Ê¨üÅé¥Ò/¤A«¬ªýÂ_¾¯¤§ÃIJz±´°Q(1/3)(Pharmacological approach of novel type alpha/beta-adrenocep-tor blocker with potassium channel blocking properties)
1999/08/01 ~ 2000/07/31
44
087 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC88-2314-B-037-010- ¡X 1 ­Ó¤H«¬
±´°Q·s«¬¨ã¦³CGRPÄÀ¥X§@¥Î¤§¥Ò/¤A«¬µÇ¤W¸¢¯À©Ê¨üÅéªýÂ_¾¯(Studies on novel alpha- and beta-adrenoceptor blockeer with an associated calcitonin gene-related peptide releasing activity)
1998/08/01 ~ 1999/07/31
45
086 ¡X N °ê¬ì·|(­ì¬ì§Þ³¡) ¡X NSC87-2314-B037-098 ¡X  
CAPSINOLOL¦b°Æ¥æ·P¯«¸g¶Ç¤J¤Î¶Ç¥X³~®|¤§ÃIJz¯S©Ê(Pharmacological characteristics of capsinolol in the parasympathetic afferent and efferent pathways)
1997/08/01 ~ 1998/07/31

 Patent

NO Patent Name Country Certified Date Patent No
1 ¯ùÆP¤Æ¦Xª«¤§§í¨î°©½è²¨ÃP¯g¬¡©Ê ¤¤µØ¥Á°ê 2013/06/21 I399205
2 ¯ùÆP¤Æ¦Xª«¤§§í¨î°©½è²¨ÃP¯g¬¡©Ê ¬ü°ê 2013/08/13 8,507,506
3 ¤@ºØTMD1³J¥Õ½è¥Î©ó»s³Æµoª¢©Ê°©¬y¥¢ÃĪ«ªº¥Î³~ ¬ü°ê 2017/10/03 9,775,885
4 TMD1 ³J¥Õ¥Î©óªv?°©½è?¥¢¯e¯f ¤¤µØ¥Á°ê 2019/02/11 I650135