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 Education

School ¡X Major ¡X Degree Duration

°ê¥ß¦¨¥\¤j¾Ç ¡X Àô¹ÒÂå¾Ç¬ã¨s©Ò(²¦) ¡X ³Õ¤h

Doctorate, Department of Environmental and Occupational Health, National Cheng Kung University

2016/09 ¡X 2022/06

°ê¥ß¦¨¥\¤j¾Ç ¡X ¥Í²z¾Ç¬ã¨s©Ò(²¦) ¡X ºÓ¤h

Master, Department of Physiology, National Cheng Kung University

2013/09 ¡X 2016/06

°ê¥ß¹Å¸q¤j¾Ç ¡X °Êª«¬ì¾Ç¨t(²¦) ¡X ¾Ç¤h

Bachelor, Department of Animal Science, National Chiayi University

2008/09 ¡X 2013/06

 Intramural Experience

Office/Department/Institute Position Duration
¥Í²z¾Ç¬ì Department of Physiology   Assistant Professor 2025/08/01 ¡X  

 Extramural Experience

 

 Discipline

 

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

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 Area(s) of Expertise & Research

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Nanotoxicology, toxicology, physiology, alternative testing

 Publication

NO Publication
1

A novel integrated testing strategy (ITS) for evaluating acute fish toxicity with new approach methodologies (NAMs).
Yen-Ling Lee#, ³¯«º¦Ð#, Tzu-Ning Li, Jian-Feng Hsueh, Ying-Jan Wang - - 1 - ENVIRONMENT INTERNATIONAL - ENVIRONMENT INTERNATIONAL 2024 193¨÷(193´Á):109112­¶
(IF: 9.7, »â°ì±Æ¦W: 25, »â°ì´Á¥Z¼Æ: 376, »â°ì±Æ¦W: 6.65%)

A novel integrated testing strategy (ITS) for evaluating acute fish toxicity with new approach methodologies (NAMs).
Yen-Ling Lee, Zi-Yu Chen, Tzu-Ning Li, Jian-Feng Hsueh, Ying-Jan Wang - - 1 - ENVIRONMENT INTERNATIONAL - ENVIRONMENT INTERNATIONAL 2024;193(193):109112
(IF: 9.7, Journal Ranking: 25, Number of Journals of this Field: 376, Ranking: 6.65%)

2

Toxic Effects and Mechanisms of Silver and Zinc Oxide Nanoparticles on Zebrafish Embryos in Aquatic Ecosystems.
Yen-Ling Lee#, Yung-Sheng Shih, ³¯«º¦Ð#, Fong-Yu Cheng, Jing-Yu Lu, Yuan-Hua Wu*, Ying-Jan Wang* - - 1 - NANOMATERIALS (BASEL, SWITZERLAND) - NANOMATERIALS (BASEL, SWITZERLAND) 2022 12¨÷(4´Á):717­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Toxic Effects and Mechanisms of Silver and Zinc Oxide Nanoparticles on Zebrafish Embryos in Aquatic Ecosystems.
Yen-Ling Lee, Yung-Sheng Shih, Zi-Yu Chen, Fong-Yu Cheng, Jing-Yu Lu, Yuan-Hua Wu, Ying-Jan Wang - - 1 - NANOMATERIALS (BASEL, SWITZERLAND) - NANOMATERIALS (BASEL, SWITZERLAND) 2022;12(4):717
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

3

Comparing different surface modifications of zinc oxide nanoparticles in the developmental toxicity of zebrafish embryos and larvae.
³¯«º¦Ð#, Yi-Chun Yang, Bour-Jr Wang#, Fong-Yu Cheng, Yen-Ling Lee, Yu-Hsuan Lee*, Ying-Jan Wang* - - 1 - ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY - ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2022 243¨÷(15´Á):113967­¶
(IF: 6.1, »â°ì±Æ¦W: 10, »â°ì´Á¥Z¼Æ: 106, »â°ì±Æ¦W: 9.43%)

Comparing different surface modifications of zinc oxide nanoparticles in the developmental toxicity of zebrafish embryos and larvae.
Zi-Yu Chen, Yi-Chun Yang, Bour-Jr Wang, Fong-Yu Cheng, Yen-Ling Lee, Yu-Hsuan Lee, Ying-Jan Wang - - 1 - ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY - ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2022;243(15):113967
(IF: 6.1, Journal Ranking: 10, Number of Journals of this Field: 106, Ranking: 9.43%)

4

Lifetime bioaccumulation of silver nanoparticles accelerates functional aging by inactivating antioxidant pathways, an effect reversed by pterostilbene
³¯«º¦Ð#, Yu-Chen Su, Fong-Yu Cheng, Shian-Jang Yan* and Ying-Jan Wang* - - 1 - Environmental Science: Nano - 2021 8¨÷(12´Á):3774-3791­¶
(IF: 0, »â°ì±Æ¦W: 0, »â°ì´Á¥Z¼Æ: 0, »â°ì±Æ¦W: -%)

Lifetime bioaccumulation of silver nanoparticles accelerates functional aging by inactivating antioxidant pathways, an effect reversed by pterostilbene
Zi-Yu Chen#, Yu-Chen Su, Fong-Yu Cheng, Shian-Jang Yan* and Ying-Jan Wang* - - 1 - Environmental Science: Nano - 2021;8(12):3774-3791
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

5

The Effect of the Chorion on Size-Dependent Acute Toxicity and Underlying Mechanisms of Amine-Modified Silver Nanoparticles in Zebrafish Embryos.
³¯«º¦Ð, Nian-Jhen Li, Fong-Yu Cheng, Jian-Feng Hsueh, Chiao-Ching Huang, Fu-I Lu, Tzu-Fun Fu, Shian-Jang Yan, Yu-Hsuan Lee, Ying-Jan Wang* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21¨÷(8´Á):2864­¶
(IF: 4.9, »â°ì±Æ¦W: 72, »â°ì´Á¥Z¼Æ: 320, »â°ì±Æ¦W: 22.50%)

The Effect of the Chorion on Size-Dependent Acute Toxicity and Underlying Mechanisms of Amine-Modified Silver Nanoparticles in Zebrafish Embryos.
Zi-Yu Chen, Nian-Jhen Li, Fong-Yu Cheng, Jian-Feng Hsueh, Chiao-Ching Huang, Fu-I Lu, Tzu-Fun Fu, Shian-Jang Yan, Yu-Hsuan Lee, Ying-Jan Wang - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(8):2864
(IF: 4.9, Journal Ranking: 72, Number of Journals of this Field: 320, Ranking: 22.50%)

6

The Current Understanding of Autophagy in Nanomaterial Toxicity and Its Implementation in Safety Assessment-Related Alternative Testing Strategies.
Rong-Jane Chen, Yu-Ying Chen, Mei-Yi Liao, Yu-Hsuan Lee, ³¯«º¦Ð, Shian-Jang Yan, Ya-Ling Yeh, Li-Xing Yang, Yen-Ling Lee, Yuan-Hua Wu, Ying-Jan Wang - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21¨÷(7´Á):2387­¶
(IF: 4.9, »â°ì±Æ¦W: 72, »â°ì´Á¥Z¼Æ: 320, »â°ì±Æ¦W: 22.50%)

The Current Understanding of Autophagy in Nanomaterial Toxicity and Its Implementation in Safety Assessment-Related Alternative Testing Strategies.
Rong-Jane Chen, Yu-Ying Chen, Mei-Yi Liao, Yu-Hsuan Lee, Zi-Yu Chen, Shian-Jang Yan, Ya-Ling Yeh, Li-Xing Yang, Yen-Ling Lee, Yuan-Hua Wu, Ying-Jan Wang - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(7):2387
(IF: 4.9, Journal Ranking: 72, Number of Journals of this Field: 320, Ranking: 22.50%)

7

Silver nanoparticles have lethal and sublethal adverse effects on development and longevity by inducing ROS-mediated stress responses.
Bin-Hsu Mao #, ³¯«º¦Ð#, Ying-Jang Wang*, Shian-Jang Yan* - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2018 8¨÷(1´Á):2445­¶
(IF: 3.9, »â°ì±Æ¦W: 25, »â°ì´Á¥Z¼Æ: 136, »â°ì±Æ¦W: 18.38%)

Silver nanoparticles have lethal and sublethal adverse effects on development and longevity by inducing ROS-mediated stress responses.
Bin-Hsu Mao, Zi-Yu Chen, Ying-Jang Wang, Shian-Jang Yan - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2018;8(1):2445
(IF: 3.9, Journal Ranking: 25, Number of Journals of this Field: 136, Ranking: 18.38%)

 Project

NO
YEAR ¡X Source ¡X No ¡X Type
Project Name
Duration
1
114 ¡X Q ·s¸u±Ð®v­pµe(®Õ¤º) ¡X KMU-Q115005 ¡X  
³z¹LªGÃǼҦ¡µo®iºC©Ê¬r©Ê²Ó­Møµe¤§·s¿³´À¥N´ú¸Õ¤èªk( )
2026/01/01 ~ 2026/12/31

 Patent