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 Education

School — Major — Degree Duration

國立成功大學 — 基礎醫學研究所(畢) — 博士

Doctorate, Institute of Basic Medical Sciences, National Cheng Kung University

2007/09 — 2014/06

中山醫學大學 — 免疫學研究所(畢) — 碩士

Master, Institute of Immunology, Chung Shan Medical University

2005/09 — 2007/06

私立中華醫事學院 — 醫事技術系(畢) — 學士

Bachelor, Department of Medical technology, Chung Hwa University of Medical Technology

2000/09 — 2002/06

 Intramural Experience

Office/Department/Institute Position Duration
生物科技學系 Department of Biotechnology   Assistant Professor 2022/08/01 —  

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 醫學之生化及分子生物 Medical Biochemistry and Molecular Biology

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

 

 

 Area(s) of Expertise & Research

表觀遺傳學 腫瘤生物學 腫瘤免疫學

Epigenetics Cancer biology Tumor Immunology

 Publication

NO Publication
1

Rab37可介導PD-1的運輸和膜表達以維持肺癌中T細胞的衰竭
Wan-Ting Kuo, 郭懿瑩, Hung-Chia Hsieh, Ssu-Ting Wu, Wu-Chou Su, Yi-Ching Wang - - 1 - JOURNAL OF BIOMEDICAL SCIENCE - JOURNAL OF BIOMEDICAL SCIENCE 2024 31卷(1期):20頁
(IF: 11, 領域排名: 13, 領域期刊數: 136, 領域排名: 9.56%)

Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer.
Wan-Ting Kuo, I-Ying Kuo, Hung-Chia Hsieh, Ssu-Ting Wu, Wu-Chou Su, Yi-Ching Wang - - 1 - JOURNAL OF BIOMEDICAL SCIENCE - JOURNAL OF BIOMEDICAL SCIENCE 2024;31(1):20
(IF: 11, Journal Ranking: 13, Number of Journals of this Field: 136, Ranking: 9.56%)

2

Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion
徐聖凱, Chon-Kit Chou, 林怡伶, 張文燦, 郭懿瑩*, 邱建智* - - 1 - CELL COMMUNICATION AND SIGNALING - CELL COMMUNICATION AND SIGNALING 2024 22卷(1期):259頁
(IF: 8.2, 領域排名: 32, 領域期刊數: 205, 領域排名: 15.61%)

Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion
Sheng-Kai Hsu, Chon-Kit Chou, I-Ling Lin, Wen-Tsan Chang, I-Ying Kuo, Chien-Chih Chiu - - 1 - CELL COMMUNICATION AND SIGNALING - CELL COMMUNICATION AND SIGNALING 2024;22(1):259
(IF: 8.2, Journal Ranking: 32, Number of Journals of this Field: 205, Ranking: 15.61%)

3

Fully human chitinase-3 like-1 monoclonal antibody inhibits tumor growth, fibrosis, angiogenesis, and immune cell remodeling in lung, pancreatic, and colorectal cancers.
Pei-Chia Su, Ching-Yu Chen, Min-Hua Yu, 郭懿瑩, Pei-Shan Yang, Ching-Hsuan Hsu, Ya-Chin Hou, Hsin-Ta Hsieh, Chih-Peng Chang, Yan-Shen Shan, Yi-Ching Wang - - 1 - BIOMEDICINE & PHARMACOTHERAPY - BIOMEDICINE & PHARMACOTHERAPY 2024 176卷(-期):116825頁
(IF: 6.9, 領域排名: 21, 領域期刊數: 189, 領域排名: 11.11%)

Fully human chitinase-3 like-1 monoclonal antibody inhibits tumor growth, fibrosis, angiogenesis, and immune cell remodeling in lung, pancreatic, and colorectal cancers.
Pei-Chia Su, Ching-Yu Chen, Min-Hua Yu, I-Ying Kuo, Pei-Shan Yang, Ching-Hsuan Hsu, Ya-Chin Hou, Hsin-Ta Hsieh, Chih-Peng Chang, Yan-Shen Shan, Yi-Ching Wang - - 1 - BIOMEDICINE & PHARMACOTHERAPY - BIOMEDICINE & PHARMACOTHERAPY 2024;176(-):116825
(IF: 6.9, Journal Ranking: 21, Number of Journals of this Field: 189, Ranking: 11.11%)

4

Revealing potential Rab proteins participate in regulation of secretory autophagy machinery
Pei-Wen Lin, Man-Ling Chu, Yu-Wen Liu, Yu-Cing Chen, Yao-Hsiang Shih, Sheng-Hui Lan, Shang-Ying Wu, 郭懿瑩, 張鴻議, 劉校生, 李英瑞 - - 1 - Kaohsiung Journal of Medical Sciences - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2024 40卷(7期):642-649頁
(IF: 2.7, 領域排名: 95, 領域期刊數: 189, 領域排名: 50.26%)

Revealing potential Rab proteins participate in regulation of secretory autophagy machinery
Pei-Wen Lin, Man-Ling Chu, Yu-Wen Liu, Yu-Cing Chen, Yao-Hsiang Shih, Sheng-Hui Lan , Shang-Ying Wu, I-Ying Kuo, Hong-Yi Chang, Hsiao-Sheng Liu, Ying-Ray Lee - - 1 - Kaohsiung Journal of Medical Sciences - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2024;40(7):642-649
(IF: 2.7, Journal Ranking: 95, Number of Journals of this Field: 189, Ranking: 50.26%)

5

腫瘤微環境中傳統及非傳統囊泡分泌途徑的最新進展
郭懿瑩, Chih‑Hsiung Hsieh, Wan‑Ting Kuo, Chih‑Peng Chang, Yi‑Ching Wang* - - 1 - Journal of Biomedical Science - JOURNAL OF BIOMEDICAL SCIENCE 2022 29卷(1期):56頁
(IF: 11, 領域排名: 13, 領域期刊數: 136, 領域排名: 9.56%)

Recent advances in conventional and unconventional vesicular secretion pathways in the tumor microenvironment
I-Ying Kuo, Chih‑Hsiung Hsieh, Wan‑Ting Kuo, Chih‑Peng Chang, Yi‑Ching Wang* - - 1 - Journal of Biomedical Science - JOURNAL OF BIOMEDICAL SCIENCE 2022;29(1):56
(IF: 11, Journal Ranking: 13, Number of Journals of this Field: 136, Ranking: 9.56%)

6

Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma.
Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, 郭懿瑩, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan, Yi-Ching Wang* - - 1 - Journal of Biomedical Science - JOURNAL OF BIOMEDICAL SCIENCE 2022 29卷(1期):90頁
(IF: 11, 領域排名: 13, 領域期刊數: 136, 領域排名: 9.56%)

Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma.
Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan, Yi-Ching Wang* - - 1 - Journal of Biomedical Science - JOURNAL OF BIOMEDICAL SCIENCE 2022;29(1):90
(IF: 11, Journal Ranking: 13, Number of Journals of this Field: 136, Ranking: 9.56%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
112 — N 國科會(原科技部) — NSTC113-2320-B-037-004 — 1 個人型
探討niclosamide舊藥新用對肺腫瘤微環境中免疫細胞CCL2/CCR2路徑之分子調控機轉( )
2024/01/01 ~ 2024/10/31
2
112 — Q 新聘教師計畫(校內) — KMU-Q113006 —  
探討FOXM1在肺癌微環境的癌細胞增生及轉移過程中所扮演的角色( )
2024/01/01 ~ 2024/12/31
3
111 — Z 大專學生研究計畫及博士後 — NSTC112-2813-C-037-063-B — 8 大專學生研究計畫
112年度大專學生研究計畫-李怡禎(生技3)( )
2023/07/01 ~ 2024/02/29

 Patent