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 Education

School — Major — Degree Duration

國立陽明大學 (中央研究院TIGP生物資訊學程) — 生物醫學資訊研究所(畢) — 博士

Doctorate, Institute of Biomedical Informatics, National Yang-Ming University (TIGP Bioinformatics Program, Academia Sinica)

2014/09 — 2018/12

國立清華大學 — 資訊系統與應用研究所(畢) — 碩士

Master, Institute of Information Systems and Applications, National Tsing Hua University

2006/09 — 2008/07

淡江大學 — 資訊管理學系(畢) — 學士

Bachelor, Department of Information Management, Tamkang University

2002/09 — 2006/06

 Intramural Experience

Office/Department/Institute Position Duration
人工智慧健康產業應用碩士學位學程   Assistant Professor 2021/09/01 —  

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 工程技術類 Engineering and Technology (11)人工智慧 Artificial Intelligence
2 工程技術類 Engineering and Technology (15)生物資訊 Bioinformatics

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

 

 

 Area(s) of Expertise & Research

生物資訊、人工智慧、機器學習、演算法設計、計算化學、醣分子科學、計算體學、結構生物學、大數據分析

Bioinformatics, Artificial Intelligence, Machine Learning, Algorithm Design, Computational Chemistry, Glycoscience, Computational Omics, Structural Biology, Big Data Analysis

 Publication

NO Publication
1

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA).
鄭成偉, Chung-Yi Wu#, Szu-Wen Wang, Jia-Yan Chen, Chih-Chuan Kung, Kuo-Shiang Liao, Chi-Huey Wong* - - 1 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2023 120卷(49期):e2314392120頁
(IF: 9.4, 領域排名: 13, 領域期刊數: 134, 領域排名: 9.70%)

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA).
Cheng-Wei Cheng, Chung-Yi Wu, Szu-Wen Wang, Jia-Yan Chen, Chih-Chuan Kung, Kuo-Shiang Liao, Chi-Huey Wong* - - 1 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2023;120(49):e2314392120
(IF: 9.4, Journal Ranking: 13, Number of Journals of this Field: 134, Ranking: 9.70%)

2

Glycosite-deleted mRNA of SARS-CoV-2 Spike Protein as a Broad-spectrum Vaccine
Chung-Yi Wu, 鄭成偉, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong* - - 1 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2022 119卷(9期):e2119995119頁
(IF: 11.1, 領域排名: 8, 領域期刊數: 73, 領域排名: 10.96%)

Glycosite-deleted mRNA of SARS-CoV-2 Spike Protein as a Broad-spectrum Vaccine
Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong* - - 1 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2022;119(9):e2119995119
(IF: 11.1, Journal Ranking: 8, Number of Journals of this Field: 73, Ranking: 10.96%)

3

Vaccination with SARS-CoV-2 Spike Protein Lacking Glycan Shields Elicits Enhanced Protective Responses in Animal Models
Han-Yi Huang#, Hsin-Yu Liao#, Xiaorui Chen#, Szu-Wen Wang#, 鄭成偉, Md Shahed-Al-Mahmud, Yo-Min Liu, Arpita Mohapatra, Ting-Hua Chen, Jennifer M Lo, Yi-Min Wu, Hsiu-Hua Ma, Yi-Hsuan Chang, Ho-Yang Tsai, Yu-Chi Chou, Yi-Ping Hsueh, Ching-Yen Tsai, Pau-Yi Huang, Sui-Yuan Chang, Tai-Ling Chao, Han-Chieh Kao, Ya-Min Tsai, Yen-Hui Chen, Chung-Yi Wu, Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Kuo-I Lin*, Che Ma*, Chi-Huey Wong* - - 1 - SCIENCE TRANSLATIONAL MEDICINE - SCIENCE TRANSLATIONAL MEDICINE 2022 eabm0899卷(eabm0899期):eabm0899頁
(IF: 17.956, 領域排名: 2, 領域期刊數: 140, 領域排名: 1.43%)

Vaccination with SARS-CoV-2 Spike Protein Lacking Glycan Shields Elicits Enhanced Protective Responses in Animal Models
Han-Yi Huang, Hsin-Yu Liao, Xiaorui Chen, Szu-Wen Wang, Cheng-Wei Cheng, Md Shahed-Al-Mahmud, Yo-Min Liu, Arpita Mohapatra, Ting-Hua Chen, Jennifer M Lo, Yi-Min Wu, Hsiu-Hua Ma, Yi-Hsuan Chang, Ho-Yang Tsai, Yu-Chi Chou, Yi-Ping Hsueh, Ching-Yen Tsai, Pau-Yi Huang, Sui-Yuan Chang, Tai-Ling Chao, Han-Chieh Kao, Ya-Min Tsai, Yen-Hui Chen, Chung-Yi Wu, Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Kuo-I Lin, Che Ma, Chi-Huey Wong - - 1 - SCIENCE TRANSLATIONAL MEDICINE - SCIENCE TRANSLATIONAL MEDICINE 2022;eabm0899(eabm0899):eabm0899
(IF: 17.956, Journal Ranking: 2, Number of Journals of this Field: 140, Ranking: 1.43%)

4

Identification of Existing Pharmaceuticals and Herbal Medicines as Inhibitors of SARS-CoV-2 Infection
Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Yu-Pu Juang, Hsiu-Hua Ma, Ying-Ta Wu, Wen-Bin Yang, 鄭成偉, Xiaorui Chen, Ting-Hung Chou, Jiun-Jie Shie, Wei-Chieh Cheng, Rong-Jie Chein, Shi-Shan Mao, Pi-Hui Liang*, Che Ma*, Shang-Cheng Hung*, Chi-Huey Wong* - - 1 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2021 118卷(5期):1-8頁
(IF: 11.205, 領域排名: 8, 領域期刊數: 73, 領域排名: 10.96%)

Identification of Existing Pharmaceuticals and Herbal Medicines as Inhibitors of SARS-CoV-2 Infection
Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Yu-Pu Juang, Hsiu-Hua Ma, Ying-Ta Wu, Wen-Bin Yang, Cheng-Wei Cheng, Xiaorui Chen, Ting-Hung Chou, Jiun-Jie Shie, Wei-Chieh Cheng, Rong-Jie Chein, Shi-Shan Mao, Pi-Hui Liang, Che Ma, Shang-Cheng Hung, Chi-Huey Wong - - 1 - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2021;118(5):1-8
(IF: 11.205, Journal Ranking: 8, Number of Journals of this Field: 73, Ranking: 10.96%)

5

Multi-Q 2 Software Facilitates Isobaric Labeling Quantitation Analysis with Improved Accuracy and Coverage
Ching-Tai Chen*, Jen-Hung Wang, 鄭成偉, Wei-Che Hsu, Chu-Ling Ko, Wai-Kok Choong, Ting-Yi Sung* - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2021 11卷(1期):2233頁
(IF: 4.379, 領域排名: 17, 領域期刊數: 73, 領域排名: 23.29%)

Multi-Q 2 Software Facilitates Isobaric Labeling Quantitation Analysis with Improved Accuracy and Coverage
Ching-Tai Chen, Jen-Hung Wang, Cheng-Wei Cheng, Wei-Che Hsu, Chu-Ling Ko, Wai-Kok Choong, Ting-Yi Sung - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2021;11(1):2233
(IF: 4.379, Journal Ranking: 17, Number of Journals of this Field: 73, Ranking: 23.29%)

6

Programmable One-Pot Synthesis of Oligosaccharides
鄭成偉, Chung-Yi Wu, Wen-Lian Hsu, Chi-Huey Wong* - - 1 - BIOCHEMISTRY - BIOCHEMISTRY 2020 59卷(34期):3078-3088頁
(IF: 3.162, 領域排名: 193, 領域期刊數: 298, 領域排名: 64.77%)

Programmable One-Pot Synthesis of Oligosaccharides
Cheng-Wei Cheng, Chung-Yi Wu, Wen-Lian Hsu, Chi-Huey Wong - - 1 - BIOCHEMISTRY - BIOCHEMISTRY 2020;59(34):3078-3088
(IF: 3.162, Journal Ranking: 193, Number of Journals of this Field: 298, Ranking: 64.77%)

7

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis
鄭成偉, Yixuan Zhou, Wen-Harn Pan, Supriya Dey, Chung-Yi Wu, Wen-Lian Hsu*, Chi-Huey Wong* - - 1 - JOVE-JOURNAL OF VISUALIZED EXPERIMENTS - JOVE-JOURNAL OF VISUALIZED EXPERIMENTS 2019 -卷(151期):e59987頁
(IF: 1.355, 領域排名: 49, 領域期刊數: 73, 領域排名: 67.12%)

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis
Cheng-Wei Cheng, Yixuan Zhou, Wen-Harn Pan, Supriya Dey, Chung-Yi Wu, Wen-Lian Hsu, Chi-Huey Wong - - 1 - JOVE-JOURNAL OF VISUALIZED EXPERIMENTS - JOVE-JOURNAL OF VISUALIZED EXPERIMENTS 2019;-(151):e59987
(IF: 1.355, Journal Ranking: 49, Number of Journals of this Field: 73, Ranking: 67.12%)

8

Hierarchical and Programmable One-pot Synthesis of Oligosaccharides
鄭成偉, Yixuan Zhou, Wen-Harn Pan, Supriya Dey, Chung-Yi Wu, Wen-Lian Hsu*, Chi-Huey Wong* - - 1 - NATURE COMMUNICATIONS - NATURE COMMUNICATIONS 2018 9卷(1期):1-9頁
(IF: 12.353, 領域排名: 3, 領域期刊數: 64, 領域排名: 4.69%)

Hierarchical and Programmable One-pot Synthesis of Oligosaccharides
Cheng-Wei Cheng, Yixuan Zhou, Wen-Harn Pan, Supriya Dey, Chung-Yi Wu, Wen-Lian Hsu, Chi-Huey Wong - - 1 - NATURE COMMUNICATIONS - NATURE COMMUNICATIONS 2018;9(1):1-9
(IF: 12.353, Journal Ranking: 3, Number of Journals of this Field: 64, Ranking: 4.69%)

9

MAGIC-web: A Platform for Untargeted and Targeted N-linked Glycoprotein Identification
T Mamie Lih, Wai-Kok Choong, Chen-Chun Chen, 鄭成偉, Hsin-Nan Lin, Ching-Tai Chen, Hui-Yin Chang, Wen-Lian Hsu, Ting-Yi Sung* - - 1 - NUCLEIC ACIDS RESEARCH - NUCLEIC ACIDS RESEARCH 2016 44卷(W1期):W575-W580頁
(IF: 16.971, 領域排名: 8, 領域期刊數: 298, 領域排名: 2.68%)

MAGIC-web: A Platform for Untargeted and Targeted N-linked Glycoprotein Identification
T Mamie Lih, Wai-Kok Choong, Chen-Chun Chen, Cheng-Wei Cheng, Hsin-Nan Lin, Ching-Tai Chen, Hui-Yin Chang, Wen-Lian Hsu, Ting-Yi Sung - - 1 - NUCLEIC ACIDS RESEARCH - NUCLEIC ACIDS RESEARCH 2016;44(W1):W575-W580
(IF: 16.971, Journal Ranking: 8, Number of Journals of this Field: 298, Ranking: 2.68%)

10

MAGIC: An Automated N-linked Glycoprotein Identification Tool Using a Y1-ion Pattern Matching Algorithm and in silico MS² Approach
Ke-Shiuan Lynn#, Chen-Chun Chen#, T Mamie Lih#, 鄭成偉, Wan-Chih Su, Chun-Hao Chang, Chia-Ying Cheng, Wen-Lian Hsu, Yu-Ju Chen*, Ting-Yi Sung* - - 1 - ANALYTICAL CHEMISTRY - ANALYTICAL CHEMISTRY 2015 87卷(4期):2466-2473頁
(IF: 6.986, 領域排名: 8, 領域期刊數: 83, 領域排名: 9.64%)

MAGIC: An Automated N-linked Glycoprotein Identification Tool Using a Y1-ion Pattern Matching Algorithm and in silico MS² Approach
Ke-Shiuan Lynn, Chen-Chun Chen, T Mamie Lih, Cheng-Wei Cheng, Wan-Chih Su, Chun-Hao Chang, Chia-Ying Cheng, Wen-Lian Hsu, Yu-Ju Chen, Ting-Yi Sung - - 1 - ANALYTICAL CHEMISTRY - ANALYTICAL CHEMISTRY 2015;87(4):2466-2473
(IF: 6.986, Journal Ranking: 8, Number of Journals of this Field: 83, Ranking: 9.64%)

11

Lipid Exposure Prediction Enhances the Inference of Rotational Angles of Transmembrane Helices
Jhih-Siang Lai#, 鄭成偉#, Allan Lo*, Ting-Yi Sung*, Wen-Lian Hsu - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2013 14卷(1期):1-16頁
(IF: 3.169, 領域排名: 16, 領域期刊數: 58, 領域排名: 27.59%)

Lipid Exposure Prediction Enhances the Inference of Rotational Angles of Transmembrane Helices
Jhih-Siang Lai, Cheng-Wei Cheng, Allan Lo, Ting-Yi Sung, Wen-Lian Hsu - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2013;14(1):1-16
(IF: 3.169, Journal Ranking: 16, Number of Journals of this Field: 58, Ranking: 27.59%)

12

Prediction of B-cell Epitopes Using Evolutionary Information and Propensity Scales
Scott Yi-Heng Lin, 鄭成偉, Emily Chia-Yu Su* - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2013 14卷(2期):1-9頁
(IF: 3.169, 領域排名: 16, 領域期刊數: 58, 領域排名: 27.59%)

Prediction of B-cell Epitopes Using Evolutionary Information and Propensity Scales
Scott Yi-Heng Lin, Cheng-Wei Cheng, Emily Chia-Yu Su - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2013;14(2):1-9
(IF: 3.169, Journal Ranking: 16, Number of Journals of this Field: 58, Ranking: 27.59%)

13

Prediction of Nuclear Proteins Using Nuclear Translocation Signals Proposed by Probabilistic Latent Semantic Indexing
Emily Chia-Yu Su*, Jia-Ming Chang, 鄭成偉, Ting-Yi Sung, Wen-Lian Hsu - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2012 13卷(17期):1-10頁
(IF: 3.169, 領域排名: 16, 領域期刊數: 58, 領域排名: 27.59%)

Prediction of Nuclear Proteins Using Nuclear Translocation Signals Proposed by Probabilistic Latent Semantic Indexing
Emily Chia-Yu Su, Jia-Ming Chang, Cheng-Wei Cheng, Ting-Yi Sung, Wen-Lian Hsu - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2012;13(17):1-10
(IF: 3.169, Journal Ranking: 16, Number of Journals of this Field: 58, Ranking: 27.59%)

14

Computational Comparative Study of Tuberculosis Proteomes Using a Model Learned from Signal Peptide Structures
Jhih-Siang Lai, 鄭成偉, Ting-Yi Sung*, Wen-Lian Hsu* - - 1 - PLOS ONE - PLOS ONE 2012 7卷(4期):e35018頁
(IF: 3.24, 領域排名: 26, 領域期刊數: 73, 領域排名: 35.62%)

Computational Comparative Study of Tuberculosis Proteomes Using a Model Learned from Signal Peptide Structures
Jhih-Siang Lai, Cheng-Wei Cheng, Ting-Yi Sung, Wen-Lian Hsu - - 1 - PLOS ONE - PLOS ONE 2012;7(4):e35018
(IF: 3.24, Journal Ranking: 26, Number of Journals of this Field: 73, Ranking: 35.62%)

15

TMPad: An Integrated Structural Database for Helix-packing Folds in Transmembrane Proteins
Allan Lo#, 鄭成偉#, Yi-Yuan Chiu#, Ting-Yi Sung*, Wen-Lian Hsu* - - 1 - NUCLEIC ACIDS RESEARCH - NUCLEIC ACIDS RESEARCH 2011 39卷(suppl_1期):D347-D355頁
(IF: 16.971, 領域排名: 8, 領域期刊數: 298, 領域排名: 2.68%)

TMPad: An Integrated Structural Database for Helix-packing Folds in Transmembrane Proteins
Allan Lo, Cheng-Wei Cheng, Yi-Yuan Chiu, Ting-Yi Sung, Wen-Lian Hsu - - 1 - NUCLEIC ACIDS RESEARCH - NUCLEIC ACIDS RESEARCH 2011;39(suppl_1):D347-D355
(IF: 16.971, Journal Ranking: 8, Number of Journals of this Field: 298, Ranking: 2.68%)

16

Predicting RNA-binding Sites of Proteins Using Support Vector Machines and Evolutionary Information
鄭成偉#, Emily Chia-Yu Su#, Jenn-Kang Hwang, Ting-Yi Sung*, Wen-Lian Hsu* - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2008 9卷(12期):1-19頁
(IF: 3.169, 領域排名: 16, 領域期刊數: 58, 領域排名: 27.59%)

Predicting RNA-binding Sites of Proteins Using Support Vector Machines and Evolutionary Information
Cheng-Wei Cheng, Emily Chia-Yu Su, Jenn-Kang Hwang, Ting-Yi Sung, Wen-Lian Hsu - - 1 - BMC BIOINFORMATICS - BMC BIOINFORMATICS 2008;9(12):1-19
(IF: 3.169, Journal Ranking: 16, Number of Journals of this Field: 58, Ranking: 27.59%)

 Project

 

 Patent