Education
| School — Major — Degree | Duration |
|---|---|
|
國立成功大學 — 基礎醫學研究所(畢) — 博士 Doctorate, The Institute of Basic Medical Sciences, National Cheng Kung University |
2002/07 — 2008/02 |
|
國立成功大學 — 微生物及免疫學研究所(畢) — 碩士 Master, Department of Microbiology and Immunology, National Cheng Kung University |
2000/07 — 2002/06 |
|
東吳大學 — 微生物學系(畢) — 學士 Bachelor, Department of Microbiology, Soochow University |
— 1996/06 |
Intramural Experience
| Office/Department/Institute | Position | Duration |
|---|---|---|
| 微生物暨免疫學科 Department of Microbiology & Immunology | Professor | 2025/08/01 — |
| 微生物暨免疫學科 Department of Microbiology & Immunology | Associate Professor | 2021/02/17 — 2025/07/31 |
Extramural Experience
| DEPNO | Position- Office/Department/Institute | Duration |
|---|---|---|
| 嘉義基督教醫院轉譯醫學研究中心 | 副研究員 | 0970501 — 1100216 |
Discipline
| NO | Discipline | Expertise |
|---|---|---|
| 1 | 生物醫農類 Biology, Medicine and Agriculture | 藥理及毒理 Pharmacology and Toxicology |
| 2 | 生物醫農類 Biology, Medicine and Agriculture | 微生物及免疫學 Microbiology and Immunology |
| 3 | 生物醫農類 Biology, Medicine and Agriculture | 血液科、腫瘤科、風濕免疫及感染科 Division of Hematology, Division of Oncology, Division of Rheumatology and Infectious Disease |
| 4 | 生物醫農類 Biology, Medicine and Agriculture | 腎臟科、新陳代謝及內分泌 Division of Nephrology, Division of Metabolism & Endocrinology |
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
Infectious Disease, Cancer Biology
Infectious Disease, Cancer Biology
Area(s) of Expertise & Research
Infectious Disease, Cancer Biology
Infectious Disease, Cancer Biology
Publication
| NO | Publication |
|---|---|
| 1 | Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection |
| 2 | 自噬活性增強可在體內和體外抑制高血糖相關的大腸直腸癌腫瘤發生 Increased autophagy activity suppresses hyperglycemia-related colorectal cancer tumorigenesis both in vitro and in vivo |
| 3 | The role of Atg5 gene in tumorigenesis under autophagy deficiency conditions. The role of Atg5 gene in tumorigenesis under autophagy deficiency conditions. |
| 4 | Revealing potential Rab proteins participate in regulation of secretory autophagy machinery Revealing potential Rab proteins participate in regulation of secretory autophagy machinery |
| 5 | CD47-mediated immune evasion in early-stage lung cancer progression. CD47-mediated immune evasion in early-stage lung cancer progression. |
| 6 | Evodiamine exerts anti-cancer activity including growth inhibition, cell cycle arrest, and apoptosis induction in human follicular thyroid cancers. Evodiamine exerts anti-cancer activity including growth inhibition, cell cycle arrest, and apoptosis induction in human follicular thyroid cancers. |
| 7 | Flavopereirine exerts anti-cancer activities in various human thyroid cancer cells. Flavopereirine exerts anti-cancer activities in various human thyroid cancer cells. |
| 8 | Honokiol Suppresses Cell Proliferation and Tumor Migration through ROS in Human Anaplastic Thyroid Cancer Cells. Honokiol Suppresses Cell Proliferation and Tumor Migration through ROS in Human Anaplastic Thyroid Cancer Cells. |
| 9 | 黃酮哌啶在多種人類甲狀腺癌細胞中發揮抗癌作用 Flavopereirine exerts anti-cancer activities in various human thyroid cancer cells |
| 10 | Piperlongumine Induces Cellular Apoptosis and Autophagy via the ROS/Akt Signaling Pathway in Human Follicular Thyroid Cancer Cells. Piperlongumine Induces Cellular Apoptosis and Autophagy via the ROS/Akt Signaling Pathway in Human Follicular Thyroid Cancer Cells. |
| 11 | RNA Interference Approach Is a Good Strategy against SARS-CoV-2. RNA Interference Approach Is a Good Strategy against SARS-CoV-2. |
| 12 | Regulation of innate immune signaling pathways by autophagy in dengue virus infection. Regulation of innate immune signaling pathways by autophagy in dengue virus infection. |
| 13 | Ivermectin induces cell cycle arrest and caspase-dependent apoptosis in human urothelial carcinoma cells. Ivermectin induces cell cycle arrest and caspase-dependent apoptosis in human urothelial carcinoma cells. |
| 14 | FAK Executes Anti-Senescence via Regulating EZH2 Signaling in Non-Small Cell Lung Cancer Cells. FAK Executes Anti-Senescence via Regulating EZH2 Signaling in Non-Small Cell Lung Cancer Cells. |
| 15 | Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro |
| 16 | Honeysuckle Aqueous Extracts Induced Suppress EV71 Replication and Pathogenesis In Vitro and In Vivo and Is Predicted to Inhibit SARS-CoV-2. Honeysuckle Aqueous Extracts Induced Suppress EV71 Replication and Pathogenesis In Vitro and In Vivo and Is Predicted to Inhibit SARS-CoV-2. |
| 17 | Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. |
| 18 | Piperlongumine, a Potent Anticancer Phytotherapeutic, Induces Cell Cycle Arrest and Apoptosis In Vitro and In Vivo through the ROS/Akt Pathway in Human Thyroid Cancer Cells. Piperlongumine, a Potent Anticancer Phytotherapeutic, Induces Cell Cycle Arrest and Apoptosis In Vitro and In Vivo through the ROS/Akt Pathway in Human Thyroid Cancer Cells. |
| 19 | 9-O-Terpenyl-Substituted Berberrubine Derivatives Suppress Tumor Migration and Increase Anti-Human Non-Small-Cell Lung Cancer Activity. 9-O-Terpenyl-Substituted Berberrubine Derivatives Suppress Tumor Migration and Increase Anti-Human Non-Small-Cell Lung Cancer Activity. |
| 20 | The Autophagosomes Containing Dengue Virus Proteins and Full-Length Genomic RNA Are Infectious. The Autophagosomes Containing Dengue Virus Proteins and Full-Length Genomic RNA Are Infectious. |
| 21 | Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection. Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection. |
Project
| NO |
YEAR — Source — No — Type
Project Name
|
Duration |
|---|---|---|
| 1 |
116 — N 國科會(原科技部) — NSTC114-2314-B-037-077-MY3 — 1 個人型
探討G9a如何透過自噬作用和SLC5A5調節促進人類甲狀腺癌腫瘤發生和放射性碘抗性的研究(3/3)( )
|
2027/08/01 ~ 2028/07/31 |
| 2 |
115 — N 國科會(原科技部) — NSTC114-2314-B-037-077-MY3 — 1 個人型
探討G9a如何透過自噬作用和SLC5A5調節促進人類甲狀腺癌腫瘤發生和放射性碘抗性的研究(2/3)( )
|
2026/08/01 ~ 2028/07/31 |
| 3 |
114 — N 國科會(原科技部) — NSTC114-2314-B-037-077-MY3 — 1 個人型
探討G9a如何透過自噬作用和SLC5A5調節促進人類甲狀腺癌腫瘤發生和放射性碘抗性的研究(1/3)( )
|
2025/08/01 ~ 2028/07/31 |
| 4 |
113 — M 高醫(種子計畫) — KMU-M114021 —
普萘洛爾對人類甲狀腺癌細胞的抗癌活性評估( )
|
2025/01/01 ~ 2025/12/31 |
| 5 |
112 — N 國科會(原科技部) — NSTC112-2314-B-037-092 — 1 個人型
探討Doxazosin抗人類膽管癌的作用及其可能機制( )
|
2023/08/01 ~ 2024/07/31 |
| 6 |
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-008-B — 8 大專學生研究計畫
113年度大專學生研究計畫-洪靜茹(公衛3)( )
|
2024/07/01 ~ 2025/02/28 |
| 7 |
111 — M 高醫(種子計畫) — KMU-M112033 —
評估Flavopereirine對人類甲狀腺癌細胞之抗癌效果( )
|
2023/01/01 ~ 2023/12/31 |
| 8 |
111 — Z 大專學生研究計畫及博士後 — NSTC112-2813-C-037-077-B — 8 大專學生研究計畫
112年度大專學生研究計畫-莫靖宇(公衛3)( )
|
2023/07/01 ~ 2024/02/29 |
| 9 |
110 — Q 新聘教師計畫(校內) — KMU-Q111008 —
Ivermectin 用於治療人類泌尿道移形細胞癌之研究( )
|
2022/01/01 ~ 2022/12/31 |
| 10 |
109 — N 國科會(原科技部) — MOST109-2314-B-037-145 — 1 個人型
探討一種新穎藥物於活體內治療人類多重抗藥性及未分化甲狀腺癌之效果與其機制，並應用於與臨床用藥協同治療( )
|
2021/02/17 ~ 2021/10/31 |
| 11 |
109 — Q 新聘教師計畫(校內) — KMU-Q110011A —
尾胡椒素用於治療未分化甲狀腺癌之應用與機制探討( )
|
2021/04/01 ~ 2021/12/31 |