Education
| School — Major — Degree | Duration |
|---|---|
|
國立陽明大學 — 醫學院臨床醫學研究所(畢) — 博士 Doctorate, , |
2007/09 — 2013/08 |
|
國立陽明大學 — 醫學技術暨工程學院放射醫學科學研究所(畢) — 碩士 Master, , |
2000/09 — 2002/06 |
|
國立陽明大學 — 醫學技術暨工程學院醫學放射技術學系(畢) — 學士 Bachelor, , |
1996/09 — 2000/06 |
Intramural Experience
| Office/Department/Institute | Position | Duration |
|---|---|---|
| 健康科學院綜合組 General Affairs Division | Head | 2024/08/01 — 2025/07/31 |
| 醫學影像暨放射科學系 Department of Medical Imaging and Radiological Sciences | Assistant Professor | 2018/08/01 — |
Extramural Experience
Discipline
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
Area(s) of Expertise & Research
輻射生物，放射腫瘤學，幹細胞生物，癌症幹細胞輻射生物，放射腫瘤學，幹細胞生物，癌症幹細胞，小動物活體分子影像
Radiation Biology, Radiation Oncology, Stem Cell Biology, Cancer stem cell, In vivo Molecular Imaging of Small Animal
Publication
| NO | Publication |
|---|---|
| 1 | Exosomes Derived from Irradiated-Prostate Cancer Cells Promote Cancer Progression Exosomes Derived from Irradiated-Prostate Cancer Cells Promote Cancer Progression |
| 2 | Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway. Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway. |
| 3 | XPF–ERCC1 Blocker Improves the Therapeutic Efficacy of 5-FU- and Oxaliplatin-Based Chemoradiotherapy in Colorectal Cancer XPF–ERCC1 Blocker Improves the Therapeutic Efficacy of 5-FU- and Oxaliplatin-Based Chemoradiotherapy in Colorectal Cancer |
| 4 | 單條和叢集染色體自動辦識之方法 Automated identification of single and clustered chromosomes for metaphase image analysis |
| 5 | SPECT/CT imaging for tracking subendothelial retention of electronegative low-density lipoprotein in vivo SPECT/CT imaging for tracking subendothelial retention of electronegative low-density lipoprotein in vivo |
| 6 | 3-溴丙酮酸對去勢抗性攝護腺癌抗癌作用的新見解 Novel insights into the anti-cancer effects of 3-bromopyruvic acid against castration-resistant prostate cancer. |
| 7 | 觀察以立體定位消融放射治療技術治療肺部腫瘤時錐狀射束電腦斷層掃描下腫瘤體積的變化 To Investigate the Relationships between Gross Tumor Volume Change Rate and Fraction Number of Stereotactic Ablative Radiotherapy for Lung Tumor by Cone Beam Computed Tomography |
| 8 | HIF-1α Expression Increases Preoperative Concurrent Chemoradiotherapy Resistance in Hyperglycemic Rectal Cancer. HIF-1α Expression Increases Preoperative Concurrent Chemoradiotherapy Resistance in Hyperglycemic Rectal Cancer. |
| 9 | ERCC1 Overexpression Increases Radioresistance in Colorectal Cancer Cells ERCC1 Overexpression Increases Radioresistance in Colorectal Cancer Cells |
| 10 | Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma |
| 11 | Protodioscin inhibits bladder cancer cell migration and growth, and promotes apoptosis through activating JNK and p38 signaling pathways. Protodioscin inhibits bladder cancer cell migration and growth, and promotes apoptosis through activating JNK and p38 signaling pathways. |
| 12 | Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe |
| 13 | Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer’s Disease Pathology and Improve Cognitive Deficits Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer’s Disease Pathology and Improve Cognitive Deficits |
| 14 | Enhancement of IUdR Radiosensitization in Cancer Therapy by Low-Energy Transmission X Ray Irradiation Enhancement of IUdR Radiosensitization in Cancer Therapy by Low-Energy Transmission X Ray Irradiation |
| 15 | Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization |
| 16 | Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer’s Disease Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer’s Disease |
| 17 | Effect of Cerenkov Radiation-Induced Photodynamic Therapy with F-18-FDG in an Intraperitoneal Xenograft Mouse Model of Ovarian Cancer. Effect of Cerenkov Radiation-Induced Photodynamic Therapy with F-18-FDG in an Intraperitoneal Xenograft Mouse Model of Ovarian Cancer. |
| 18 | Preclinical Characterization and In Vivo Imaging of In-111-Labeled Mesenchymal Stem Cell-Derived Extracellular Vesicles. Preclinical Characterization and In Vivo Imaging of In-111-Labeled Mesenchymal Stem Cell-Derived Extracellular Vesicles. |
| 19 | Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapy for Alzheimer’s Disease: Progress and Opportunity Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapy for Alzheimer’s Disease: Progress and Opportunity |
| 20 | Mesenchymal Stem Cell-Derived Extracellular Vesicle: A Promising Alternative Therapy for Osteoporosis Mesenchymal Stem Cell-Derived Extracellular Vesicle: A Promising Alternative Therapy for Osteoporosis |
| 21 | Multiplexed Molecular Imaging Strategy Integrated with RNA Sequencing in the Assessment of the Therapeutic Effect of Wharton’s Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles for Osteoporosis Multiplexed Molecular Imaging Strategy Integrated with RNA Sequencing in the Assessment of the Therapeutic Effect of Wharton’s Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles for Osteoporosis |
| 22 | Genetic Analysis Reveals a Significant Contribution of to Prostate Cancer Progression in Taiwanese Men. Genetic Analysis Reveals a Significant Contribution of to Prostate Cancer Progression in Taiwanese Men. |
| 23 | Correlation of 18F-FDG uptake and thyroid cancer stem cells Correlation of 18F-FDG uptake and thyroid cancer stem cells |
| 24 | Combined treatment of sodium ferulate, n‐butylidenephthalide, and ADSCs rehabilitates neurovascular unit in rats after photothrombotic stroke Combined treatment of sodium ferulate, n‐butylidenephthalide, and ADSCs rehabilitates neurovascular unit in rats after photothrombotic stroke |
| 25 | Performance Evaluation of a Novel Preclinical Micro-CT System In Vitro and In Vivo Performance Evaluation of a Novel Preclinical Micro-CT System In Vitro and In Vivo |
| 26 | Ginseng-Angelica-Sansheng-Pulvis Boosts Neurogenesis Against Focal Cerebral Ischemia-Induced Neurological Deficiency Ginseng-Angelica-Sansheng-Pulvis Boosts Neurogenesis Against Focal Cerebral Ischemia-Induced Neurological Deficiency |
| 27 | Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke |
| 28 | 急慢性酒精中毒對大鼠腦部代謝乙酸能力的影響 Effects of the acute and chronic ethanol intoxication on acetate metabolism and kinetics in the rat brain |
| 29 | Quantitative Measurement of the Thyroid Uptake Function of Mouse by Cerenkov Luminescence Imaging Quantitative Measurement of the Thyroid Uptake Function of Mouse by Cerenkov Luminescence Imaging |
Project
| NO |
YEAR — Source — No — Type
Project Name
|
Duration |
|---|---|---|
| 1 |
116 — N 國科會(原科技部) — NSTC114-2314-B-037-090-MY3 — 1 個人型
高血糖結直腸癌輻射抗性的機轉探討及外泌載體攜帶干擾核酸與奈米粒子的放射增敏治療策略開發(3/3)( )
|
2027/08/01 ~ 2028/07/31 |
| 2 |
115 — N 國科會(原科技部) — NSTC114-2314-B-037-090-MY3 — 1 個人型
高血糖結直腸癌輻射抗性的機轉探討及外泌載體攜帶干擾核酸與奈米粒子的放射增敏治療策略開發(2/3)( )
|
2026/08/01 ~ 2028/07/31 |
| 3 |
114 — N 國科會(原科技部) — NSTC114-2314-B-037-090-MY3 — 1 個人型
高血糖結直腸癌輻射抗性的機轉探討及外泌載體攜帶干擾核酸與奈米粒子的放射增敏治療策略開發(1/3)( )
|
2025/08/01 ~ 2028/07/31 |
| 4 |
114 — NK 高醫-中山合作計畫 — — 1 個人型
細胞外泌體包覆奈米金粒子靶向多形性膠質母細胞瘤的放射治療增敏效果之評估(Evaluation of radiosensitizing effectiveness of gold nanoparticles encapsulated in exosomes targeted for glioblastoma (GBM) radiotherapy)
|
2025/01/01 ~ 2025/12/31 |
| 5 |
113 — N 國科會(原科技部) — NSTC113-2314-B-037-065 — 1 個人型
探討血漿外泌體作為高血糖結直腸癌患者放射化學治療預後的臨床診斷預測指標及其中高糖環境下癌症的輻射抗性調控機轉( )
|
2024/08/01 ~ 2025/07/31 |
| 6 |
112 — Z 大專學生研究計畫及博士後 — NSTC113-2813-C-037-072-B — 8 大專學生研究計畫
113年度大專學生研究計畫-朱澐虹(醫放2)( )
|
2024/07/01 ~ 2025/02/28 |
| 7 |
111 — M 高醫(種子計畫) — KMU-M112016 —
探討高血糖結直腸癌者患血漿外泌體生物標誌作為評估同步化學放射治療療效指標及探討高糖刺激之癌細胞外泌體對大腸癌進展之調控( )
|
2023/01/01 ~ 2023/12/31 |
| 8 |
110 — M 高醫(種子計畫) — KMU-M111011 —
探討輻射照射後攝護腺癌細 胞之外泌體及 POTEE 蛋白對微 環境癌細胞的生理調控機制( )
|
2022/01/01 ~ 2022/12/31 |
| 9 |
109 — DK 前瞻重點(原校院) — KMU-DK(B)110005-3 —
透過液態檢測高血糖結直腸癌病患之外泌體內抗性因子作為放射線合併化學藥物療效評估方式( )
|
2021/01/01 ~ 2021/12/31 |
| 10 |
109 — M 高醫(種子計畫) — KMU-M110010A —
間葉幹細胞之外泌體治療骨質疏鬆症之療效，可能機轉及活體分子影像追蹤(III)( )
|
2021/01/01 ~ 2021/12/31 |
| 11 |
109 — Z 大專學生研究計畫及博士後 — MOST110-2813-C-037-028-B — 8 大專學生研究計畫
110年度大專學生研究計畫-黃可欣(醫放2)( )
|
2021/07/01 ~ 2022/02/28 |
| 12 |
108 — N 國科會(原科技部) — MOST108-2314-B-037-015 — 1 個人型
間葉幹細胞之外泌體治療骨質疏鬆症之療效，可能機轉 及活體分子影像追蹤 (II)( )
|
2019/08/01 ~ 2020/10/31 |
| 13 |
108 — Q 新聘教師計畫(校內) — KMU-Q109004 —
利用間葉幹細胞外泌體治療阿茲海默病之研究( )
|
2020/01/01 ~ 2020/12/31 |
| 14 |
107 — N 國科會(原科技部) — MOST107-2314-B-037-119 — 1 個人型
無細胞之幹細胞療法:間葉幹細胞外泌體治療骨質疏鬆症之療效，可能機轉及活體分子影像追蹤( )
|
2018/08/01 ~ 2019/07/31 |
| 15 |
107 — N 國科會(原科技部) — MOST107-2623-E-037-001-NU — 1 個人型
研發結合含碘藥物IUdR與特定能量之X光照射在癌症治療之新技術( )
|
2018/08/01 ~ 2018/12/31 |
| 16 |
107 — N 國科會(原科技部) — MOST106-2314-B-037-099 — 1 個人型
發展去乙醯基酶抑制劑對甲狀腺癌症幹細胞特異療法之研究( )
|
2018/08/01 ~ 2018/10/31 |
| 17 |
107 — Q 新聘教師計畫(校內) — KMU-Q108018 —
探討去乙醯基酶抑制劑對甲狀腺癌症幹細胞去分化影響及治療應用( )
|
2019/01/01 ~ 2019/12/31 |