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 Education

School — Major — Degree Duration

高雄醫學大學 — 牙醫學系(畢) — 博士

Doctorate, School of Dentistry, Kaohsiung Medical University

2008/09 — 2013/06

高雄醫學大學 — 口腔衛生學系(畢) — 碩士

Master, department of Oral Hygiene, Kaohsiung Medical University

2006/09 — 2008/06

高雄醫學大學 — 口腔衛生學系(畢) — 學士

Bachelor, department of Oral Hygiene, Kaohsiung Medical University

2002/09 — 2005/06

 Intramural Experience

Office/Department/Institute Position Duration
臨床醫學研究部 Department of Medical Research       —  
牙醫學系 School of Dentistry   Professor 2024/02/01 —  
研究發展處行政規劃組 Division of Administrative Planning   Head 2023/08/01 — 2024/07/31
牙醫學系 School of Dentistry   Associate Professor 2020/08/01 — 2024/01/31
牙醫學系 School of Dentistry   Assistant Professor 2017/08/01 — 2020/07/31

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 生物學之生化及分子生物 Biochemistry and Molecular Biology
2 生物醫農類 Biology, Medicine and Agriculture 牙科 Division of Dentistry

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

癌症轉譯醫學、口腔公共衛生、臨床試驗

 

 Area(s) of Expertise & Research

癌症轉譯醫學、臨床試驗口腔分子生物、癌症轉譯醫學、臨床試驗

Oral molecular biology, cancer translation medicine, clinical trial

 Publication

NO Publication
1

細胞質與核 RAD51 表現對乳癌進展和患者預後的不同影響。
汪硯雲, 鄭光宏, 洪純道, Steven Lo, 陳邦宇, 吳益嘉, 侯明鋒, 袁行修* - - 1 - INTERNATIONAL JOURNAL OF ONCOLOGY - INTERNATIONAL JOURNAL OF ONCOLOGY 2024 64卷(2期):12頁
(IF: 5.2, 領域排名: 72, 領域期刊數: 241, 領域排名: 29.88%)

Differential impact of cytoplasmic vs. nuclear RAD51 expression on breast cancer progression and patient prognosis.
Yen-Yun Wang, Kuang-Hung Cheng, Amos C Hung, Steven Lo, Pang-Yu Chen, Yi-Chia Wu, Ming-Feng Hou, Shyng-Shiou F Yuan - - 1 - INTERNATIONAL JOURNAL OF ONCOLOGY - INTERNATIONAL JOURNAL OF ONCOLOGY 2024;64(2):12
(IF: 5.2, Journal Ranking: 72, Number of Journals of this Field: 241, Ranking: 29.88%)

2

IL17RB expression is associated with malignant cancer behaviors and poor prognosis in oral cancer.
袁行修#, 蘇昶瑋#, 曾良鵬, 阮得幸孝, 陳玉昆, 杜哲光, 鄭光宏, 汪硯雲* - - 1 - ORAL DISEASES - ORAL DISEASES 2024 30卷(4期):2027-2038頁
(IF: 3.8, 領域排名: 19, 領域期刊數: 91, 領域排名: 20.88%)

IL17RB expression is associated with malignant cancer behaviors and poor prognosis in oral cancer.
Shyng-Shiou F Yuan, Chang-Wei Su, Leong-Perng Chan, Hieu D H Nguyen, Yuk-Kwan Chen, Je-Kang Du, Kuang-Hung Cheng, Yen-Yun Wang - - 1 - ORAL DISEASES - ORAL DISEASES 2024;30(4):2027-2038
(IF: 3.8, Journal Ranking: 19, Number of Journals of this Field: 91, Ranking: 20.88%)

3

富馬酸水合酶通過失活 AMPK 和上調 DAB2 抑制非小細胞肺癌轉移
Anupama Vadhan, 楊宜芳, 王雲銘, 陳邦宇, 鄒協成, 鄭光宏, 胡楚松, 鄭添祿, 汪硯雲*, 袁行修* - - 1 - ONCOLOGY LETTERS - ONCOLOGY LETTERS 2023 25卷(1期):42頁
(IF: 3.111, 領域排名: 176, 領域期刊數: 245, 領域排名: 71.84%)

Fumarate hydratase inhibits non‑small cell lung cancer metastasis via inactivation of AMPK and upregulation of DAB2
Anupama Vadhan#, Yi-Fang Yang, Yun-Ming Wang, Pang-Yu Chen, Shey-Cherng Tzou, Kuang-Hung Cheng, Stephen Chu sung Hu, Tian-Lu Cheng, Yen-Yun Wang*, Shyng-Shiou F. Yuan* - - 1 - ONCOLOGY LETTERS - ONCOLOGY LETTERS 2023;25(1):42
(IF: 3.111, Journal Ranking: 176, Number of Journals of this Field: 245, Ranking: 71.84%)

4

Overexpression of transient receptor potential melastatin 6 during human oral squamous cell carcinogenesis.
汪硯雲#,王文岑#,蘇昶瑋,許經偉,袁行修*, 陳玉昆* - - 1 - JOURNAL OF DENTAL SCIENCES - JOURNAL OF DENTAL SCIENCES 2023 18卷(1期):382-391頁
(IF: 3.5, 領域排名: 26, 領域期刊數: 91, 領域排名: 28.57%)

Overexpression of transient receptor potential melastatin 6 during human oral squamous cell carcinogenesis.
Yen-Yun Wang#, Wen-Chen Wang#, Chiang-Wei Sue, Ching-Wei Hsu, Shyng-Shiou Yuan*, Yuk-Kwan Chen* - - 1 - JOURNAL OF DENTAL SCIENCES - JOURNAL OF DENTAL SCIENCES 2023;18(1):382-391
(IF: 3.5, Journal Ranking: 26, Number of Journals of this Field: 91, Ranking: 28.57%)

5

Sprouty 4 在人口腔鱗狀細胞癌變中的表現
廖倍顯#, 莊富雄#, 汪硯雲#, 王文岑, 蘇昶瑋, 許經偉, 袁行修*, 陳玉昆* - - 1 - Journal of Dental Sciences - JOURNAL OF DENTAL SCIENCES 2023 18卷(2期):781-790頁
(IF: 3.5, 領域排名: 26, 領域期刊數: 91, 領域排名: 28.57%)

Sprouty 4 expression in human oral squamous cell carcinogenesis
Pei-Hsien Liao #, Fu-Hsiung Chuang #, Yen-Yun Wang #, Wen-Chen Wang, Chiang-Wei Su, Ching-Wei Hsu, Shyng-Shiou Yuan*, Yuk-Kwan Chen* - - 1 - Journal of Dental Sciences - JOURNAL OF DENTAL SCIENCES 2023;18(2):781-790
(IF: 3.5, Journal Ranking: 26, Number of Journals of this Field: 91, Ranking: 28.57%)

6

FeCo 金屬有機骨架的分層組合強化泡沫鎳作為阻抗傳感器檢測人體樣品中的 IL-1RA
Priya Vijayaraghavan#, 汪硯雲#, Sathyadevi Palanisamy, 李莉芸, 陳玉昆, 鄒協成, 袁行修*, 王雲銘* - - 1 - CHEMICAL ENGINEERING JOURNAL - CHEMICAL ENGINEERING JOURNAL 2023 458卷(15 Februar期):141444頁
(IF: 15.1, 領域排名: 5, 領域期刊數: 142, 領域排名: 3.52%)

Hierarchical ensembles of FeCo metal-organic frameworks reinforced nickel foam as an impedimetric sensor for detection of IL-1RA in human samples
Priya Vijayaraghavan # , Yen-Yun Wang # , Sathyadevi Palanisamy, Li-Yun Lee , Yuk-Kwan Chen , Shey-Cherng Tzou, Shyng-Shiou F. Yuan*, Yun-Ming Wang* - - 1 - CHEMICAL ENGINEERING JOURNAL - CHEMICAL ENGINEERING JOURNAL 2023;458(15 Februar):141444
(IF: 15.1, Journal Ranking: 5, Number of Journals of this Field: 142, Ranking: 3.52%)

7

Effect of esophageal cancer screening on mortality among patients with oral cancer and second primary esophageal cancer in Taiwan.
陳以勳, 何綺玫, 許文鴻, 汪硯雲, 袁行修, 謝慧敏*, 吳宜珍* - - 1 - AMERICAN JOURNAL OF OTOLARYNGOLOGY - AMERICAN JOURNAL OF OTOLARYNGOLOGY 2023 44卷(4期):103856頁
(IF: 2.5, 領域排名: 16, 領域期刊數: 43, 領域排名: 37.21%)

Effect of esophageal cancer screening on mortality among patients with oral cancer and second primary esophageal cancer in Taiwan.
Yi-Hsun Chen, Chi-Mei Ho, Meng-Shieh Wu, Wen-Hung Hsu, Winnie Yen-Yun Wang, Shyng-Shiou F Yuan, Hui-Min Hsieh, I-Chen Wu - - 1 - AMERICAN JOURNAL OF OTOLARYNGOLOGY - AMERICAN JOURNAL OF OTOLARYNGOLOGY 2023;44(4):103856
(IF: 2.5, Journal Ranking: 16, Number of Journals of this Field: 43, Ranking: 37.21%)

8

IL-1RA通過線粒體代謝介導的EGFR/JNK/SOX2通路促進口腔鱗狀細胞癌惡變。
袁行修, 王雲銘, 曾良鵬, 洪純道, 阮得幸孝, 陳玉昆, 胡楚松, Steven Lo, 汪硯雲* - - 1 - JOURNAL OF TRANSLATIONAL MEDICINE - JOURNAL OF TRANSLATIONAL MEDICINE 2023 21卷(1期):473頁
(IF: 7.4, 領域排名: 29, 領域期刊數: 136, 領域排名: 21.32%)

IL-1RA promotes oral squamous cell carcinoma malignancy through mitochondrial metabolism-mediated EGFR/JNK/SOX2 pathway.
Shyng-Shiou F Yuan, Yun-Ming Wang, Leong-Perng Chan, Amos C Hung, Hieu D H Nguyen, Yuk-Kwan Chen, Stephen Chu-Sung Hu, Steven Lo, Yen-Yun Wang - - 1 - JOURNAL OF TRANSLATIONAL MEDICINE - JOURNAL OF TRANSLATIONAL MEDICINE 2023;21(1):473
(IF: 7.4, Journal Ranking: 29, Number of Journals of this Field: 136, Ranking: 21.32%)

9

Fumarate hydratase functions as a tumor suppressor in endometrial cancer by inactivating EGFR signaling.
汪硯雲, Anupama Vadhan, 吳鏡瑚, Cheng-Yang Hsu, 陳渝潔, 陳玉昆, 陳邦宇, 阮得幸校, 張玉泉, 袁行修* - - 1 - ONCOLOGY REPORTS - ONCOLOGY REPORTS 2023 50卷(4期):183頁
(IF: 4.2, 領域排名: 94, 領域期刊數: 241, 領域排名: 39.00%)

Fumarate hydratase functions as a tumor suppressor in endometrial cancer by inactivating EGFR signaling.
Yen-Yun Wang, Anupama Vadhan, Ching-Hu Wu, Cheng-Yang Hsu, Yu-Chieh Chen, Yuk-Kwan Chen, Pang-Yu Chen, Hieu D H Nguyen, Yu-Chiuan Chang, Shyng-Shiou F Yuan* - - 1 - ONCOLOGY REPORTS - ONCOLOGY REPORTS 2023;50(4):183
(IF: 4.2, Journal Ranking: 94, Number of Journals of this Field: 241, Ranking: 39.00%)

10

RAD51是口腔鱗狀細胞癌的不良預後標記和潛在的治療標靶
蔡郁棻, 曾良鵬, 陳玉昆, 蘇昶瑋, 許經偉, 汪硯雲*, 袁行修* - - 1 - CANCER CELL INTERNATIONAL - CANCER CELL INTERNATIONAL 2023 23卷(1期):231頁
(IF: 5.8, 領域排名: 59, 領域期刊數: 241, 領域排名: 24.48%)

RAD51 is a poor prognostic marker and a potential therapeutic target for oral squamous cell carcinoma.
Yu-Fen Tsai, Leong-Perng Chan, Yuk-Kwan Chen, Chang-Wei Su, Ching-Wei Hsu, Yen-Yun Wang*, Shyng-Shiou F Yuan* - - 1 - CANCER CELL INTERNATIONAL - CANCER CELL INTERNATIONAL 2023;23(1):231
(IF: 5.8, Journal Ranking: 59, Number of Journals of this Field: 241, Ranking: 24.48%)

11

Expression of Orai1 and STIM1 in human oral squamous cell carcinogenesis
汪硯雲#,王文岑#,蘇昶瑋,許經偉,袁行修*, 陳玉昆* - - 1 - Journal of Dental Sciences - JOURNAL OF DENTAL SCIENCES 2022 17卷(1期):78-88頁
(IF: 3.719, 領域排名: 23, 領域期刊數: 92, 領域排名: 25.00%)

Expression of Orai1 and STIM1 in human oral squamous cell carcinogenesis
Yen-Yun Wang#, Wen-Chen Wang#, Chiang-Wei Sue, Ching-Wei Hsu, Shyng-Shiou Yuan*, Yuk-Kwan Chen* - - 1 - Journal of Dental Sciences - JOURNAL OF DENTAL SCIENCES 2022;17(1):78-88
(IF: 3.719, Journal Ranking: 23, Number of Journals of this Field: 92, Ranking: 25.00%)

12

CD44 Mediates Oral Squamous Cell Carcinoma-Promoting Activity of MRE11 via AKT Signaling.
袁行修,洪純道,許經偉,藍鼎勛,蘇昶瑋,紀宗辰,張玉泉,陳玉昆,汪硯雲* - - 1 - JOURNAL OF PERSONALIZED MEDICINE - JOURNAL OF PERSONALIZED MEDICINE 2022 12卷(5期):841頁
(IF: 3.508, 領域排名: 41, 領域期刊數: 109, 領域排名: 37.61%)

CD44 Mediates Oral Squamous Cell Carcinoma-Promoting Activity of MRE11 via AKT Signaling.
Shyng-Shiou F Yuan, Amos C Hung, Ching-Wei Hsu, Ting-Hsun Lan, Chang-Wei Su, Tsung-Chen Chi, Yu-Chiuan Chang, Yuk-Kwan Chen, Yen-Yun Wang - - 1 - JOURNAL OF PERSONALIZED MEDICINE - JOURNAL OF PERSONALIZED MEDICINE 2022;12(5):841
(IF: 3.508, Journal Ranking: 41, Number of Journals of this Field: 109, Ranking: 37.61%)

13

Effects of DSM-5 Betel-Quid-Related Symptoms, Pathological Behaviors, and Use Disorder on Oral Squamous Cell Carcinoma Risk
王文岑, 邱約慈, 汪硯雲, 呂帥倫, 曾良鵬, 李純瑩, Frances M Yang, 袁行修*, 李建宏* - - 1 - CANCERS - CANCERS 2022 14卷(16期):3974頁
(IF: 6.575, 領域排名: 60, 領域期刊數: 245, 領域排名: 24.49%)

Effects of DSM-5 Betel-Quid-Related Symptoms, Pathological Behaviors, and Use Disorder on Oral Squamous Cell Carcinoma Risk
Wen-Chen Wang, Yueh-Tzu Chiu, Yen-Yun Wang, Shuai-Lun Lu, Leong-Perng Chan, Chun-Ying Lee, Frances M Yang, Shyng-Shiou F Yuan*, Chien-Hung Lee* - - 1 - CANCERS - CANCERS 2022;14(16):3974
(IF: 6.575, Journal Ranking: 60, Number of Journals of this Field: 245, Ranking: 24.49%)

14

Comparative effectiveness and stage-shift effect of endoscopic exam among newly diagnosed oral cancer patients with different stages in Taiwan.
何綺玫, 陳以勳, 許文鴻, 汪硯雲, 袁行修, 吳宜珍*, 謝慧敏* - - 1 - HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK - HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 2022 44卷(10期):2118-2128頁
(IF: 3.821, 領域排名: 6, 領域期刊數: 43, 領域排名: 13.95%)

Comparative effectiveness and stage-shift effect of endoscopic exam among newly diagnosed oral cancer patients with different stages in Taiwan.
Chi-Mei Ho, Yi-Hsun Chen, Wen-Hung Hsu, Winnie Yen-Yun Wang, Shyng-Shiou F Yuan, I-Chen Wu, Hui-Min Hsieh - - 1 - HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK - HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 2022;44(10):2118-2128
(IF: 3.821, Journal Ranking: 6, Number of Journals of this Field: 43, Ranking: 13.95%)

15

在乳腺癌共培養模型中,抵抗素刺激的 ADSCs 通過 CXCL5 促進乳腺癌細胞惡化
汪硯雲#,洪純道#, 吳益嘉, Steven Lo, 陳奐達, 陳玉昆, 謝雅晶, 胡楚松, 侯明鋒, 袁行修* - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2022 12卷(1期):15437頁
(IF: 4.996, 領域排名: 19, 領域期刊數: 73, 領域排名: 26.03%)

ADSCs stimulated by resistin promote breast cancer cell malignancy via CXCL5 in a breast cancer coculture model.
Yen-Yun Wang#, Amos C Hung#, Yi-Chia Wu, Steven Lo, Huan-Da Chen, Yuk-Kwan Chen, Ya-Ching Hsieh, Stephen Chu-Sung Hu, Ming-Feng Hou, Shyng-Shiou F Yuan - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2022;12(1):15437
(IF: 4.996, Journal Ranking: 19, Number of Journals of this Field: 73, Ranking: 26.03%)

16

CD44 通過 AKT下調FOXA2 促進乳腺癌轉移
Anupama Vadhan#, 侯明鋒, Priya Vijayaraghavan,吳益嘉, 胡楚松, 王雲銘, 鄭添祿, 汪硯雲*, 袁行修* - - 1 - BIOMEDICINES - BIOMEDICINES 2022 10卷(10期):2488頁
(IF: 4.757, 領域排名: 86, 領域期刊數: 279, 領域排名: 30.82%)

CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2.
Anupama Vadhan, Ming-Feng Hou, Priya Vijayaraghavan, Yi-Chia Wu, Stephen Chu-Sung Hu, Yun-Ming Wang, Tian-Lu Cheng, Yen-Yun Wang, Shyng-Shiou F Yuan - - 1 - BIOMEDICINES - BIOMEDICINES 2022;10(10):2488
(IF: 4.757, Journal Ranking: 86, Number of Journals of this Field: 279, Ranking: 30.82%)

17

Overexpression of sprouty 1 protein in human oral squamous cell carcinogenesis.
汪硯雲#,王文岑#,蘇昶瑋,許經偉,袁行修*,陳玉昆* - - 1 - Journal of dental sciences - JOURNAL OF DENTAL SCIENCES 2021 16卷(1期):21-28頁
(IF: 2.08, 領域排名: 59, 領域期刊數: 91, 領域排名: 64.84%)

Overexpression of sprouty 1 protein in human oral squamous cell carcinogenesis.
Yen-Yun Wang#,Wen-Chen Wang#,Chiang-Wei Su,Ching-Wei Hsu,Shyng-Shiou Yuan*,Yuk-Kwan Chen* - - 1 - Journal of dental sciences - JOURNAL OF DENTAL SCIENCES 2021;16(1):21-28
(IF: 2.08, Journal Ranking: 59, Number of Journals of this Field: 91, Ranking: 64.84%)

18

Adipocytokines visfatin and resistin in breast cancer: Clinical relevance, biological mechanisms, and therapeutic potential
汪硯雲#,洪純道,StevenLo*,袁行修* - - 1 - Cancer Letters - CANCER LETTERS 2021 498卷(-期):229-239頁
(IF: 8.679, 領域排名: 34, 領域期刊數: 242, 領域排名: 14.05%)

Adipocytokines visfatin and resistin in breast cancer: Clinical relevance, biological mechanisms, and therapeutic potential
Yen-Yun Wang, Amos C. Hung, Steven Lo*, Shyng-Shiou F. Yuan* - - 1 - Cancer Letters - CANCER LETTERS 2021;498(-):229-239
(IF: 8.679, Journal Ranking: 34, Number of Journals of this Field: 242, Ranking: 14.05%)

19

Excision repair cross-complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence
汪硯雲,方本詞#,蘇昶瑋,陳玉昆,黃志中,黃旼儀*,袁行修* - - 1 - Oncology Letters - ONCOLOGY LETTERS 2021 21卷(6期):450頁
(IF: 2.967, 領域排名: 184, 領域期刊數: 242, 領域排名: 76.03%)

Excision repair cross-complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence
Yen-Yun Wang, Pen-Tzu Fang#, Chang-Wei Su, Yuk-Kwan Chen, Joh-Jong Huang, Ming-Yii Huang*, Shyng-Shiou F. Yuan* - - 1 - Oncology Letters - ONCOLOGY LETTERS 2021;21(6):450
(IF: 2.967, Journal Ranking: 184, Number of Journals of this Field: 242, Ranking: 76.03%)

20

MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner.
汪硯雲,陳玉昆,StevenLo,紀宗辰,陳怡華,胡楚松,陳雅雯,江士昇,蔡芳瑜,劉旺達,李瑞年,謝雅晶,黃志仁,袁行修* - - 1 - Oncogene - ONCOGENE 2021 40卷(20期):3510-3532頁
(IF: 9.867, 領域排名: 29, 領域期刊數: 298, 領域排名: 9.73%)

MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner.
Yen-Yun Wang, Yuk-Kwan Chen, Steven Lo, Tsung-Chen Chi, Yi-Hua Chen, Stephen Chu-Sung Hu, Ya-Wen Chen, Shih Sheng Jiang, Fang-Yu Tsai, Wangta Liu, Ruei-Nian Li, Ya-Ching Hsieh, Chih-Jen Huang, Shyng-Shiou F Yuan* - - 1 - Oncogene - ONCOGENE 2021;40(20):3510-3532
(IF: 9.867, Journal Ranking: 29, Number of Journals of this Field: 298, Ranking: 9.73%)

21

MRE11 as a molecular signature and therapeutic target for cancer treatment with radiotherapy.
汪硯雲,洪純道,StevenLo,謝雅晶,袁行修* - - 1 - Cancer letters - CANCER LETTERS 2021 514卷(21期):1-11頁
(IF: 8.679, 領域排名: 34, 領域期刊數: 242, 領域排名: 14.05%)

MRE11 as a molecular signature and therapeutic target for cancer treatment with radiotherapy.
Yen-Yun Wang,Amos C Hung,Steven Lo,Ya-Ching Hsieh,Shyng-Shiou F Yuan - - 1 - Cancer letters - CANCER LETTERS 2021;514(21):1-11
(IF: 8.679, Journal Ranking: 34, Number of Journals of this Field: 242, Ranking: 14.05%)

22

Evaluation of the Feasibility of NaCaPO4-Blended Zirconia as a New CAD/CAM Material for Dental Restoration
藍鼎勛*,陳裕豐,汪硯雲,周明奇 - - 1 - Materials - MATERIALS 2021 14卷(14期):3819頁
(IF: 3.623, 領域排名: 17, 領域期刊數: 80, 領域排名: 21.25%)

Evaluation of the Feasibility of NaCaPO4-Blended Zirconia as a New CAD/CAM Material for Dental Restoration
Ting-Hsun Lan, Yu-Feng Chen, Yen-Yun Wang, Mitch M. C. Chou - - 1 - Materials - MATERIALS 2021;14(14):3819
(IF: 3.623, Journal Ranking: 17, Number of Journals of this Field: 80, Ranking: 21.25%)

23

CD44 Promotes Lung Cancer Cell Metastasis through ERK-ZEB1 Signaling
汪硯雲,Anupama Vadhan,陳丙何,李彥龍,趙志燁,鄭光宏,張玉泉,胡楚松,袁行修* - - 1 - Cancers (Basel) - CANCERS 2021 13卷(16期):4057頁
(IF: 6.639, 領域排名: 51, 領域期刊數: 242, 領域排名: 21.07%)

CD44 Promotes Lung Cancer Cell Metastasis through ERK-ZEB1 Signaling
Yen-Yun Wang, Anupama Vadhan , Ping-Ho Chen , Yen-Lung Lee , Chih-Yeh Chao, Kuang-Hung Cheng , Yu-Chiuan Chang , Stephen Chu-Sung Hu , Shyng-Shiou F Yuan * - - 1 - Cancers (Basel) - CANCERS 2021;13(16):4057
(IF: 6.639, Journal Ranking: 51, Number of Journals of this Field: 242, Ranking: 21.07%)

24

Reduced tissue and serum resistin expression as a clinical marker for esophageal squamous cell carcinoma
洪純道, 汪硯雲, 李坤宗, 姜宏興,陳玉昆, 杜哲光, 陳俊明, 陳遠謙,陳癸菁, 胡楚松, 袁行修* - - 1 - Oncology Letters - ONCOLOGY LETTERS 2021 22卷(5期):774頁
(IF: 2.967, 領域排名: 184, 領域期刊數: 242, 領域排名: 76.03%)

Reduced tissue and serum resistin expression as a clinical marker for esophageal squamous cell carcinoma
AMOS C. HUNG, YEN‑YUN WANG, KUN‑TSUNG LEE, HUNG‑HSING CHIANG,YUK-KWAN CHEN, JE‑KANG DU, CHUN-MING CHEN, MICHAEL YUANCHIEN CHEN,KWEI‑JING CHEN, STEPHEN CHU-SUNG HU and SHYNG‑SHIOU F. YUAN* - - 1 - Oncology Letters - ONCOLOGY LETTERS 2021;22(5):774
(IF: 2.967, Journal Ranking: 184, Number of Journals of this Field: 242, Ranking: 76.03%)

25

Decreased Circulating Melatonin with Loss of Age-Related Biphasic Change in Patients with Oral Squamous Cell Carcinoma
蔡郁棻, 汪硯雲, 蔡婉琪, 蘇昶瑋, 許經偉, 袁行修* - - 1 - Journal of Personalized Medicine - JOURNAL OF PERSONALIZED MEDICINE 2021 11卷(12期):1357頁
(IF: 4.945, 領域排名: 15, 領域期刊數: 108, 領域排名: 13.89%)

Decreased Circulating Melatonin with Loss of Age-Related Biphasic Change in Patients with Oral Squamous Cell Carcinoma
Yu-Fen Tsai, Yen-Yun Wang, Wan-Chi Tsai, Chang-Wei Su, Ching-Wei Hsu and Shyng-Shiou F. Yuan* - - 1 - Journal of Personalized Medicine - JOURNAL OF PERSONALIZED MEDICINE 2021;11(12):1357
(IF: 4.945, Journal Ranking: 15, Number of Journals of this Field: 108, Ranking: 13.89%)

26

Genetic and Proteinic Linkage of MAO and COMT with Oral Potentially Malignant Disorders and Cancers of the Oral Cavity and Pharynx.
陳丙何, 汪硯雲, 藍鼎勛, 曾良鵬, 袁行修* - - 1 - CANCERS - CANCERS 2021 13卷(13期):3268頁
(IF: 6.575, 領域排名: 60, 領域期刊數: 245, 領域排名: 24.49%)

Genetic and Proteinic Linkage of MAO and COMT with Oral Potentially Malignant Disorders and Cancers of the Oral Cavity and Pharynx.
Ping-Ho Chen, Yen-Yun Wang, Ting-Hsun Lan, Leong-Perng Chan, Shyng-Shiou Yuan* - - 1 - CANCERS - CANCERS 2021;13(13):3268
(IF: 6.575, Journal Ranking: 60, Number of Journals of this Field: 245, Ranking: 24.49%)

27

A Comparison of Two Molecular Methods for Detecting CALR Mutations in Myeloproliferative Neoplasms.
Tzu-Hsien Chan, 汪硯雲, Chih-Chieh Chen, Wen-Li Huang, I-Yen Lin, 余志強 - - 1 - CLINICAL LABORATORY - CLINICAL LABORATORY 2021 67卷(9期):--頁
(IF: 1.053, 領域排名: 26, 領域期刊數: 29, 領域排名: 89.66%)

A Comparison of Two Molecular Methods for Detecting CALR Mutations in Myeloproliferative Neoplasms.
Tzu-Hsien Chan, Yen-Yun Wang, Chih-Chieh Chen, Wen-Li Huang, I-Yen Lin, Tze-Kiong Er - - 1 - CLINICAL LABORATORY - CLINICAL LABORATORY 2021;67(9):--
(IF: 1.053, Journal Ranking: 26, Number of Journals of this Field: 29, Ranking: 89.66%)

28

Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo
汪硯雲, 蕭綾儀, 吳寶珠, 陳玉昆, Steven Lo, 胡楚松, 陳怡華, 邱建智, 袁行修* - - 1 - Biochemical Pharmacology - BIOCHEMICAL PHARMACOLOGY 2020 171卷(-期):113713頁
(IF: 4.96, 領域排名: 27, 領域期刊數: 271, 領域排名: 9.96%)

Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo
Yen Yun Wang, Ling Yi Xiao, Pao Chu Wu, Yuk Kwan Chen, Steven Lo, Stephen Chu Sung Hu, Yi Hua Chen, Charles Chien Chih Chiu, Shyng Shiou F. Yuan* - - 1 - Biochemical Pharmacology - BIOCHEMICAL PHARMACOLOGY 2020;171(-):113713
(IF: 4.96, Journal Ranking: 27, Number of Journals of this Field: 271, Ranking: 9.96%)

29

Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer
鮑永定#, 汪硯雲#, 陳玉昆, 蘇昶瑋, 許經偉, 蕭綾儀, 袁行修*, 李瑞年* - - 1 - oral diseases - ORAL DISEASES 2020 26卷(4期):756-765頁
(IF: 2.613, 領域排名: 19, 領域期刊數: 91, 領域排名: 20.88%)

Silencing of FOXA2 decreases E‐cadherin expression and is associated with lymph node metastasis in oral cancer
Yung‐Ding Bow#, Yen‐Yun Wang#, Yuk‐Kwan Chen, Chang‐Wei Su, Ching‐Wei Hsu, Ling‐yi Xiao, Shyng‐Shiou Yuan*, Ruei‐Nian Li* - - 1 - oral diseases - ORAL DISEASES 2020;26(4):756-765
(IF: 2.613, Journal Ranking: 19, Number of Journals of this Field: 91, Ranking: 20.88%)

30

Comet tail, an indicator for DNA damage or repair?: Refers to Liu et al. Oral Oncology 2020 Jan;100:104469
蔡郁棻, 汪硯雲, 袁行修* - - 1 - Oral Oncology - ORAL ONCOLOGY 2020 104卷(-期):104624頁
(IF: 3.979, 領域排名: 5, 領域期刊數: 91, 領域排名: 5.49%)

Comet tail, an indicator for DNA damage or repair?: Refers to Liu et al. Oral Oncology 2020 Jan;100:104469
Yu-Fen Tsai, Yen-Yun Wang, Shyng-Shiou F. Yuan* - - 1 - Oral Oncology - ORAL ONCOLOGY 2020;104(-):104624
(IF: 3.979, Journal Ranking: 5, Number of Journals of this Field: 91, Ranking: 5.49%)

31

EMI2 expression as a poor prognostic factor in patients with breast cancer
Anupama Vadhan, 汪硯雲, 袁行修, 李怡琛, 胡楚松, Jyuan-Yuan Huang, Takashi Ishikawa, 侯明鋒* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2020 36卷(8期):640-648頁
(IF: 1.291, 領域排名: 114, 領域期刊數: 136, 領域排名: 83.82%)

EMI2 expression as a poor prognostic factor in patients with breast cancer
Anupama Vadhan, Yen-Yun Wang, Shyng-Shiou F. Yuan, Yi-Chen Lee, Stephen Chu-Sung Hu, Jyuan-Yuan Huang, Takashi Ishikawa, Ming-Feng Hou* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2020;36(8):640-648
(IF: 1.291, Journal Ranking: 114, Number of Journals of this Field: 136, Ranking: 83.82%)

32

Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo
汪硯雲, 蕭綾儀, 陳玉昆, 吳寶珠, 陳怡樺, 胡楚松, 袁行修* - - 1 - ACS Omega - ACS OMEGA 2020 5卷(12期):7018–7024頁
(IF: 2.584, 領域排名: 76, 領域期刊數: 172, 領域排名: 44.19%)

Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo
Yen-Yun Wang, Ling-Yi Xiao, Yuk-Kwan Chen, Pao-Chu Wu, Yi-Hua Chen, Stephen Chu-Sung Hu, and Shyng-Shiou F. Yuan* - - 1 - ACS Omega - ACS OMEGA 2020;5(12):7018–7024
(IF: 2.584, Journal Ranking: 76, Number of Journals of this Field: 172, Ranking: 44.19%)

33

DNA repair protein Rad51 induces tumor growth and metastasis in esophageal squamous cell carcinoma via a p38/Akt dependent pathway
邱文進#, 方本詞#, 李怡琛, 汪硯雲, 蘇郁涵, 胡楚松, 陳玉昆, 徐雨棠, 高英軒, 黃旼儀*, 袁行修* - - 1 - Annals of Surgical Oncology - ANNALS OF SURGICAL ONCOLOGY 2020 20卷(20期):20頁
(IF: 4.339, 領域排名: 37, 領域期刊數: 213, 領域排名: 17.37%)

DNA repair protein Rad51 induces tumor growth and metastasis in esophageal squamous cell carcinoma via a p38/Akt dependent pathway
Wen-Chin Chiu#, Pen-Tzu Fang#, Yi-Chen Lee, Yen-Yun Wang, Yu-Han Su, Stephen Chu-Sung Hu, Yuk-Kwan Chen, Yu-Tong Tsui, Ying-Hsien Kao, Ming-Yii Huang*, Shyng-Shiou F. Yuan* - - 1 - Annals of Surgical Oncology - ANNALS OF SURGICAL ONCOLOGY 2020;20(20):20
(IF: 4.339, Journal Ranking: 37, Number of Journals of this Field: 213, Ranking: 17.37%)

34

IMPAD1 Functions as Mitochondrial Electron Transport Inhibitor That Prevents ROS Production and Promotes Lung Cancer Metastasis Through the AMPK-Notch1-HEY1 Pathway
楊宜芳, 汪硯雲, 蕭宏昇, Steven Lo, Yu-Chan Chang, Yi-Hua Jan, Tsung-Ching Lai, 李怡琛, Ya-Ching Hsieh, 袁行修* - - 1 - CANCER LETTERS - CANCER LETTERS 2020 15卷(485期):27-37頁
(IF: 6.508, 領域排名: 29, 領域期刊數: 230, 領域排名: 12.61%)

IMPAD1 Functions as Mitochondrial Electron Transport Inhibitor That Prevents ROS Production and Promotes Lung Cancer Metastasis Through the AMPK-Notch1-HEY1 Pathway
Yi-Fang Yang, Yen-Yun Wang, Michael Hsiao, Steven Lo, Yu-Chan Chang, Yi-Hua Jan, Tsung-Ching Lai, Yi-Chen Lee, Ya-Ching Hsieh, Shyng-Shiou F Yuan* - - 1 - CANCER LETTERS - CANCER LETTERS 2020;15(485):27-37
(IF: 6.508, Journal Ranking: 29, Number of Journals of this Field: 230, Ranking: 12.61%)

35

Low Concentration of Withaferin a Inhibits Oxidative Stress-Mediated Migration and Invasion in Oral Cancer Cells
余姿蓉, 湯人仰, 歐陽賦, 汪硯雲, 袁行修, Kevin Tseng, Li-Ching Lin*, 張學偉* - - 1 - Biomolecules - BIOMOLECULES 2020 10卷(5期):777頁
(IF: 4.879, 領域排名: 96, 領域期刊數: 298, 領域排名: 32.21%)

Low Concentration of Withaferin a Inhibits Oxidative Stress-Mediated Migration and Invasion in Oral Cancer Cells
Tzu-Jung Yu, Jen-Yang Tang, Fu Ou-Yang, Yen-Yun Wang, Shyng-Shiou F Yuan, Kevin Tseng, Li-Ching Lin*, Hsueh-Wei Chang* - - 1 - Biomolecules - BIOMOLECULES 2020;10(5):777
(IF: 4.879, Journal Ranking: 96, Number of Journals of this Field: 298, Ranking: 32.21%)

36

Methanol Extract ofUsnea barbataInduces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress
湯人仰, 吳光涵, 汪硯雲, Ammad Ahmad Farooqi, Hurng-Wern Huang, 袁行修, Ru-In Jian, Li-Yi Tsao, Po-An Chen, 張芳榮, 鄭源斌, 胡皓竣*, 張學偉* - - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2020 9卷(8期):694頁
(IF: 6.312, 領域排名: 11, 領域期刊數: 144, 領域排名: 7.64%)

Methanol Extract ofUsnea barbataInduces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress
Jen-Yang Tang, Kuang-Han Wu, Yen-Yun Wang, Ammad Ahmad Farooqi, Hurng-Wern Huang, Shyng-Shiou F Yuan, Ru-In Jian, Li-Yi Tsao, Po-An Chen, Fang-Rong Chang, Yuan-Bin Cheng, Hao-Chun Hu*, Hsueh-Wei Chang* - - 1 - Antioxidants (Basel, Switzerland) - ANTIOXIDANTS 2020;9(8):694
(IF: 6.312, Journal Ranking: 11, Number of Journals of this Field: 144, Ranking: 7.64%)

37

Combined Treatment of Sulfonyl Chromen-4-Ones (CHW09) and Ultraviolet-C (UVC) Enhances Proliferation Inhibition, Apoptosis, Oxidative Stress, and DNA Damage against Oral Cancer Cells.
王聖傑, 汪硯雲, Li-Ching Lin, 張夢揚, 袁行修, 湯人仰*, 張學偉* - - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21卷(17期):6443頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Combined Treatment of Sulfonyl Chromen-4-Ones (CHW09) and Ultraviolet-C (UVC) Enhances Proliferation Inhibition, Apoptosis, Oxidative Stress, and DNA Damage against Oral Cancer Cells.
Sheng-Chieh Wang, Yen-Yun Wang, Li-Ching Lin, Meng-Yang Chang, Shyng-Shiou F Yuan, Jen-Yang Tang*, Hsueh-Wei Chang* - - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(17):6443
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

38

Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model
Ling-YuHuang#,Yi-PingHsieh#,汪硯雲#,黃道揚#,ShihShengJiang#,Wen-TsungHuang#,Wei-FanChiang,劉柯俊,黃則達* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21卷(21期):8171頁
(IF: 4.556, 領域排名: 74, 領域期刊數: 297, 領域排名: 24.92%)

Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model
Ling-Yu Huang #,Yi-Ping Hsieh # ,Yen-Yun Wang # ,Daw-Yang Hwang # ,Shih Sheng Jiang # ,Wen-Tsung Huang # ,Wei-Fan Chiang ,Ko-Jiunn Liu , Tze-Ta Huang* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(21):8171
(IF: 4.556, Journal Ranking: 74, Number of Journals of this Field: 297, Ranking: 24.92%)

39

Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages
汪硯雲,陳奐達,StevenLo,陳玉昆,黃鈺淇,胡楚松,謝雅晶,洪純道,侯明鋒,袁行修* - - 1 - Cancers - CANCERS 2020 12卷(12期):3526頁
(IF: 6.126, 領域排名: 37, 領域期刊數: 244, 領域排名: 15.16%)

Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages
Yen-Yun Wang #, Huan-Da Chen , Steven Lo , Yuk-Kwan Chen , Yu-Ci Huang , Stephen Chu-Sung Hu , Ya-Ching Hsieh , Amos C Hung , Ming-Feng Hou , Shyng-Shiou F Yuan* - - 1 - Cancers - CANCERS 2020;12(12):3526
(IF: 6.126, Journal Ranking: 37, Number of Journals of this Field: 244, Ranking: 15.16%)

40

Low Dose Combined Treatment with Ultraviolet-C and Withaferin a Enhances Selective Killing of Oral Cancer Cells
彭聖堯, 汪硯雲, 藍鼎勳, 林立青, 袁行修, 湯人仰*, 張學偉* - - 1 - Antioxidants (Basel) - ANTIOXIDANTS 2020 9卷(11期):1120頁
(IF: 6.312, 領域排名: 11, 領域期刊數: 144, 領域排名: 7.64%)

Low Dose Combined Treatment with Ultraviolet-C and Withaferin a Enhances Selective Killing of Oral Cancer Cells
Sheng-Yao Peng, Yen-Yun Wang, Ting-Hsun Lan, Li-Ching Lin, Shyng-Shiou F Yuan, Jen-Yang Tang*, Hsueh-Wei Chang* - - 1 - Antioxidants (Basel) - ANTIOXIDANTS 2020;9(11):1120
(IF: 6.312, Journal Ranking: 11, Number of Journals of this Field: 144, Ranking: 7.64%)

41

CYP26A1新穎標記與檳榔相關口腔及咽癌
陳丙何, 鍾加明, 汪硯雲, 黃弘文, 黃斌, 李家和, 袁行修, 吳哲維, 林莉萱, 曾良鵬* - - 1 - Diagnostics (Basel, Switzerland) - DIAGNOSTICS 2020 10卷(11期):982頁
(IF: 3.706, 領域排名: 45, 領域期刊數: 169, 領域排名: 26.63%)

CYP26A1 Is a Novel Biomarker for Betel Quid-Related Oral and Pharyngeal Cancers.
Ping-Ho Chen, Chia-Min Chung, Yen-Yun Wang, Hurng-Wern Huang, Bin Huang, Ka-Wo Lee, Shyng-Shiou Yuan, Che-Wei Wu, Lee-Shuan Lin, Leong-Perng Chan* - - 1 - Diagnostics (Basel, Switzerland) - DIAGNOSTICS 2020;10(11):982
(IF: 3.706, Journal Ranking: 45, Number of Journals of this Field: 169, Ranking: 26.63%)

42

Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients
黃志仁,黃旼儀,方本詞,陳韋廷, 王昱蒼,陳中和,袁行修, 黃鈞民, 羅逵皓, 莊弘毅, 汪硯雲, 李欣樺* - - 1 - American Journal of Clinical Nutrition - AMERICAN JOURNAL OF CLINICAL NUTRITION 2019 109卷(3期):606-614頁
(IF: 6.766, 領域排名: 6, 領域期刊數: 89, 領域排名: 6.74%)

Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients
Chih-Jen Huang, Ming-Yii Huang, Pen-Tzu Fang, Frank Chen, Yu-Tsang Wang, Chung-Ho Chen, Shyng-Shiou Yuan, Chun-Ming Huang, Kuei-Hau Luo, Hung-Yi Chuang, Yen-Yun Wang, and Hsin-Hua Lee* - - 1 - American Journal of Clinical Nutrition - AMERICAN JOURNAL OF CLINICAL NUTRITION 2019;109(3):606-614
(IF: 6.766, Journal Ranking: 6, Number of Journals of this Field: 89, Ranking: 6.74%)

43

MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death
汪硯雲, 陳玉昆, 胡楚松, 蕭綾儀, 黃婉綾, 紀宗辰, 鄭光宏, 王雲銘*, 袁行修* - - 1 - Oral Diseases - ORAL DISEASES 2019 25卷(3期):758-771頁
(IF: 2.613, 領域排名: 19, 領域期刊數: 91, 領域排名: 20.88%)

MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death
Wang YY, Chen YK, Hu CS, Xiao LY, Huang WL, Chi TC, Cheng KH, Wang YM*, Yuan SF* - - 1 - Oral Diseases - ORAL DISEASES 2019;25(3):758-771
(IF: 2.613, Journal Ranking: 19, Number of Journals of this Field: 91, Ranking: 20.88%)

44

Influence of Tea Consumption on the Development of Second Esophageal Neoplasm in Patients with Head and Neck Cancer
王耀廣,陳威昌(共同第一),賴瑩荷, 陳以勳,吳明蒼,郭啟東,汪硯雲, 袁行修, 劉于鵬*,吳宜珍* - - 1 - Cancers (Basel) - CANCERS 2019 11卷(3期):E387頁
(IF: 6.162, 領域排名: 31, 領域期刊數: 230, 領域排名: 13.48%)

Influence of Tea Consumption on the Development of Second Esophageal Neoplasm in Patients with Head and Neck Cancer
Wang YK, Chen WC, Lai YH, Chen YH, Wu MT, Kuo CT, Wang YY, Yuan SF, Liu YP, Wu IC* - - 1 - Cancers (Basel) - CANCERS 2019;11(3):E387
(IF: 6.162, Journal Ranking: 31, Number of Journals of this Field: 230, Ranking: 13.48%)

45

Essential Role of Visfatin in Lipopolysaccharide and Colon Ascendens Stent Peritonitis-Induced Acute Lung Injury
李怡琛,林俊祐,陳彥旭,邱文進,汪硯雲,許勤,胡楚松,袁行修* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019 20卷(-期):1687頁
(IF: 4.556, 領域排名: 74, 領域期刊數: 297, 領域排名: 24.92%)

Essential Role of Visfatin in Lipopolysaccharide and Colon Ascendens Stent Peritonitis-Induced Acute Lung Injury
YC Lee, CY Lin,YH Chen,WC Chiu,YY Wang, C Hsu ,CS Hu, YH Su,SS Yuan* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019;20(-):1687
(IF: 4.556, Journal Ranking: 74, Number of Journals of this Field: 297, Ranking: 24.92%)

46

YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells.
楊宜芳,李怡琛,汪硯雲,王啟鴻,侯明鋒,袁行修* - - 1 - Kaohsiung J Med Sci. - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2019 2019卷(2019期):1-9頁
(IF: 1.291, 領域排名: 114, 領域期刊數: 136, 領域排名: 83.82%)

YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells.
Yang YF, Lee YC, Wang YY, Wang CH, Hou MF, Yuan SF*. - - 1 - Kaohsiung J Med Sci. - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES 2019;2019(2019):1-9
(IF: 1.291, Journal Ranking: 114, Number of Journals of this Field: 136, Ranking: 83.82%)

47

Manoalide preferentially provides antiproliferation of oral cancer cells by oxidative stress-mediated apoptosis and DNA damage
Hui-Ru Wang,湯人仰, 汪硯雲, Ammad Ahmad Farooqi, Ching-Yu Yen, 袁行修, 黃弘文*, 張學偉* - - 1 - Cancers - CANCERS 2019 11卷(9期):1303頁
(IF: 6.126, 領域排名: 37, 領域期刊數: 244, 領域排名: 15.16%)

Manoalide preferentially provides antiproliferation of oral cancer cells by oxidative stress-mediated apoptosis and DNA damage
Hui-Ru Wang, Jen-Yang Tang, Yen-Yun Wang, Ammad Ahmad Farooqi, Ching-Yu Yen, Shyng-Shiou F. Yuan, Hurng-Wern Huang*, Hsueh-Wei Chang* - - 1 - Cancers - CANCERS 2019;11(9):1303
(IF: 6.126, Journal Ranking: 37, Number of Journals of this Field: 244, Ranking: 15.16%)

48

Visfatin mediates malignant behaviors through adipose-derived stem cells intermediary in breast cancer
黃俊淵, 汪硯雲, Steven Lo, Ling-Ming Tseng, Dar-Ren Chen, 吳益嘉, 侯明鋒, 袁行修* - - 1 - Cancers (Basel) - CANCERS 2019 12卷(1期):29頁
(IF: 6.162, 領域排名: 31, 領域期刊數: 230, 領域排名: 13.48%)

Visfatin mediates malignant behaviors through adipose-derived stem cells intermediary in breast cancer
Jyun-Yuan Huang, Yen-Yun Wang, Steven Lo, Ling-Ming Tseng, Dar-Ren Chen, Yi-Chia Wu, Ming-Feng Hou, Shyng-Shiou F. Yuan * - - 1 - Cancers (Basel) - CANCERS 2019;12(1):29
(IF: 6.162, Journal Ranking: 31, Number of Journals of this Field: 230, Ranking: 13.48%)

49

Overexpression of sprouty2 in human oral squamous cell carcinog enesis.
廖倍顯,#汪硯雲#,王文岑#,陳中和,高郁勳,許經偉,陳靜怡,陳丙何,袁行修*,陳玉昆* - - 1 - Archives of Oral Biology - ARCHIVES OF ORAL BIOLOGY 2018 87卷(2018期):131-142頁
(IF: 2.05, 領域排名: 28, 領域期刊數: 91, 領域排名: 30.77%)

Overexpression of sprouty2 in human oral squamous cell carcinog enesis.
Liao PH#, Wang YY#, Wang WC#, Chen CH, Kao YH, Hsu JW, Chen CY, Chen PH, Yuan SS, Chen YK. - - 1 - Archives of Oral Biology - ARCHIVES OF ORAL BIOLOGY 2018;87(2018):131-142
(IF: 2.05, Journal Ranking: 28, Number of Journals of this Field: 91, Ranking: 30.77%)

50

Evaluation of the mRNA expression levels of integrins α3, α5, β1 and β6 as tumor biomarkers of oral squamous cell carcinoma
張學偉, 顏欽堉, 陳中和, 蔡閏旭, 湯人仰, YUNG-TING CHANG, 高郁勛, 汪硯雲, 袁行修,SHENG-YANG LEE* - - 1 - Oncology Letters - ONCOLOGY LETTERS 2018 16卷(16期):4773-4781頁
(IF: 1.664, 領域排名: 194, 領域期刊數: 224, 領域排名: 86.61%)

Evaluation of the mRNA expression levels of integrins α3, α5, β1 and β6 as tumor biomarkers of oral squamous cell carcinoma
HSUEH-WEI CHANG, CHING-YU YEN, CHUNG-HO CHEN ,JUN-HSU TSAI , JEN-YANG TANG, YUNG-TING CHANG, YU-HSUN KAO, YEN-YUN WANG, SHYNG-SHIOU F. YUAN,SHENG-YANG LEE* - - 1 - Oncology Letters - ONCOLOGY LETTERS 2018;16(16):4773-4781
(IF: 1.664, Journal Ranking: 194, Number of Journals of this Field: 224, Ranking: 86.61%)

51

3'-Hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells
蔡駿豪, 謝沛文,李怡琛,王啟鴻,邱文進,呂淳雯,汪硯雲,胡楚松, 鄭添祿, 袁行修* - - 1 - LIFE SCIENCES - MEDICINE, RESEARCH & EXPERIMENTAL  2017 172卷(2017期):19-26頁
(IF: 2.936, 領域排名: 45, 領域期刊數: 128, 領域排名: 35.16%)

3'-Hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells
Tsai CH, Hsieh PW, Lee YC, Wang CH, Chiu WC, Lu CW, Wang YY, Hu SC, Cheng TL, Yuan SF* - - 1 - LIFE SCIENCES - MEDICINE, RESEARCH & EXPERIMENTAL  2017;172(2017):19-26
(IF: 2.936, Journal Ranking: 45, Number of Journals of this Field: 128, Ranking: 35.16%)

52

Novel quantitative analysis of autofluorescence images for oral cancer screening.
黃則達,黃振勳,汪硯雲,陳坤仲,王東堯,陳怡君,吳哲維,曾良鵬,林奕筑,高郁勛,二岡祥子,袁行修*,詹寶珠* - - 1 - Oral Oncol - ORAL ONCOL 2017 68卷(-期):20-26頁
(IF: 4.794, 領域排名: 1, 領域期刊數: 90, 領域排名: 1.11%)

Novel quantitative analysis of autofluorescence images for oral cancer screening.
Huang TT, Huang JS, Wang YY, Chen KC, Wong TY, Chen YC, Wu CW, Chan LP, Lin YC, Kao YH, Nioka S, Yuan SF*, Chung PC*. - - 1 - Oral Oncol - ORAL ONCOL 2017;68(-):20-26
(IF: 4.794, Journal Ranking: 1, Number of Journals of this Field: 90, Ranking: 1.11%)

53

Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.
汪硯雲,陳玉昆,許雅玲,邱文進,蔡峻豪,胡楚松,謝佩文,袁行修* - - 1 - Head Neck - Head Neck 2017 39卷(6期):1055-1064頁
(IF: 3.376, 領域排名: 1, 領域期刊數: 42, 領域排名: 2.38%)

Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.
Wang YY, Chen YK, Hsu YL, Chiu WC, Tsai CH, Hu SC, Hsieh PW, Yuan SF. - - 1 - Head Neck - Head Neck 2017;39(6):1055-1064
(IF: 3.376, Journal Ranking: 1, Number of Journals of this Field: 42, Ranking: 2.38%)

54

CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis.
汪硯雲,陳玉昆,胡楚松,許雅玲,蔡峻豪,紀宗辰,謝佩文,袁行修* - - 1 - CANCER CHEMOTHERAPY AND PHARMACOLOGY - CANCER CHEMOTH PHARM 2017 79卷(6期):1129-1140頁
(IF: 2.737, 領域排名: 112, 領域期刊數: 256, 領域排名: 43.75%)

CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis.
Wang YY, Chen YK, Hu SC, Hsu YL, Tsai CH, Chi TC, Huang WL, Hsieh PW, Yuan SF* - - 1 - CANCER CHEMOTHERAPY AND PHARMACOLOGY - CANCER CHEMOTH PHARM 2017;79(6):1129-1140
(IF: 2.737, Journal Ranking: 112, Number of Journals of this Field: 256, Ranking: 43.75%)

55

CYT-Rx20 Inhibits Cervical Cancer Cell Growth and Migration Through Oxidative Stress-Induced DNA Damage, Cell Apoptosis, and Epithelial-to-Mesenchymal Transition Inhibition
汪硯雲,謝佩文,陳玉昆,胡楚松,許雅玲,蔡峻豪,袁行修* - - 1 - INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER - INT J GYNECOL CANCER 2017 27卷(7期):1306-1317頁
(IF: 2.369, 領域排名: 30, 領域期刊數: 80, 領域排名: 37.50%)

CYT-Rx20 Inhibits Cervical Cancer Cell Growth and Migration Through Oxidative Stress-Induced DNA Damage, Cell Apoptosis, and Epithelial-to-Mesenchymal Transition Inhibition
Wang, YY, Hsieh, PW, Chen, YK,Hu, SCS,Hsu, YL ,Tsai, CH,Yuan, SSF* - - 1 - INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER - INT J GYNECOL CANCER 2017;27(7):1306-1317
(IF: 2.369, Journal Ranking: 30, Number of Journals of this Field: 80, Ranking: 37.50%)

56

The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
邱文進,李怡琛,蘇郁涵, 汪硯雲,蔡駿豪,侯怡安,王啟鴻 , 黃英峰,黃志仁,周世華,謝珮文, 袁行修* - - 1 - PLoS One  - PLOS ONE 2016 11卷(11期):e0166453頁
(IF: 3.057, 領域排名: 11, 領域期刊數: 63, 領域排名: 17.46%)

The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
Chiu WC, Lee YC, Su YH, Wang YY, Tsai CH, Hou YA, Wang CH , Huang YF, Huang CJ, Chou SH, Hsieh PW, Yuan SF* - - 1 - PLoS One  - PLOS ONE 2016;11(11):e0166453
(IF: 3.057, Journal Ranking: 11, Number of Journals of this Field: 63, Ranking: 17.46%)

57

Molecular characterization of oral squamous cell carcinoma using targeted next-generation sequencing.
余志強#,汪硯雲#,陳志傑,Herreros-Villanueva,劉大智,袁行修* - - 1 - Oral Diseases - Oral Dis 2015 21卷(7期):872-878頁
(IF: 2.427, 領域排名: 17, 領域期刊數: 88, 領域排名: 19.32%)

Molecular characterization of oral squamous cell carcinoma using targeted next-generation sequencing.
Er TK, Wang YY, Chen CC, Herreros-Villanueva M, Liu TC, Yuan SS. - - 1 - Oral Diseases - Oral Dis 2015;21(7):872-878
(IF: 2.427, Journal Ranking: 17, Number of Journals of this Field: 88, Ranking: 19.32%)

58

The association between the RAGE G82S polymorphism, sRAGE and chronic periodontitis in Taiwanese individuals with and without diabetes.
王俐琄,蔡吉政,汪硯雲,何坤炎,吳逸民,洪信嘉,林英助* - - 1 - JOURNAL OF PERIODONTAL RESEARCH - J Periodontal Res. 2015 50卷(6期):881-9頁
(IF: 2.466, 領域排名: 16, 領域期刊數: 88, 領域排名: 18.18%)

The association between the RAGE G82S polymorphism, sRAGE and chronic periodontitis in Taiwanese individuals with and without diabetes.
Wu TL, Tsai CC, Wang YY, Ho KY, Wu YM, Hung HC, Lin YC. - - 1 - JOURNAL OF PERIODONTAL RESEARCH - J Periodontal Res. 2015;50(6):881-9
(IF: 2.466, Journal Ranking: 16, Number of Journals of this Field: 88, Ranking: 18.18%)

59

Association study between novel CYP26 polymorphisms and the risk of betel quid-related malignant oral disorders.
吳世忠,Yun-Ju Chen,謝天渝,陳俊明,汪硯雲,李坤宗,Yueh-Ming Lin,Pei-Hsuan Chien,陳丙何* - - 1 - TheScientificWorldJournal - ScientificWorldJournal 2014 2015卷(2015期):160-185頁
(IF: 1.055, 領域排名: 13, 領域期刊數: 59, 領域排名: 22.03%)

Association study between novel CYP26 polymorphisms and the risk of betel quid-related malignant oral disorders.
Wu SJ, Chen YJ, Shieh TY, Chen CM, Wang YY, Lee KT, Lin YM, Chien PH, Chen PH. - - 1 - TheScientificWorldJournal - ScientificWorldJournal 2014;2015(2015):160-185
(IF: 1.055, Journal Ranking: 13, Number of Journals of this Field: 59, Ranking: 22.03%)

60

Plasma polyunsaturated fatty acids and periodontal recovery in Taiwanese with periodontitis: a significant relationship.
王勝宏,洪信嘉,蔡吉政,黃孟娟,何坤炎,吳逸民,汪硯雲,林英助* - - 1 - Archivers of Oral Biology - Arch Oral Biol. 2014 59卷(8期):800-807頁
(IF: 1.689, 領域排名: 23, 領域期刊數: 83, 領域排名: 27.71%)

Plasma polyunsaturated fatty acids and periodontal recovery in Taiwanese with periodontitis: a significant relationship.
Wang SH, Hung HC, Tsai CC, Huang MC, Ho KY, Wu YM, Wang YY, Lin YC. - - 1 - Archivers of Oral Biology - Arch Oral Biol. 2014;59(8):800-807
(IF: 1.689, Journal Ranking: 23, Number of Journals of this Field: 83, Ranking: 27.71%)

61

Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders.
汪硯雲,戴延宣,王文岑,陳靜怡,高郁勳,陳玉昆*,陳中和* - - 1 - BMC Oral Health - BMC Oral Health 2014 14卷(14期):99頁
(IF: 1.147, 領域排名: 48, 領域期刊數: 83, 領域排名: 57.83%)

Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders.
Wang YY, Tail YH, Wang WC, Chen CY, Kao YH, Chen YK, Chen CH. - - 1 - BMC Oral Health - BMC Oral Health 2014;14(14):99
(IF: 1.147, Journal Ranking: 48, Number of Journals of this Field: 83, Ranking: 57.83%)

62

Polymorphisms in Kallikrein7 and 10 genes and oral cancer risks in Taiwan betel quid chewers and smokers.
汪硯雲,林英助,洪信嘉,田婉諭,謝天渝* - - 1 - Oral Diseases - Oral Dis 2013 19卷(8期):824-832頁
(IF: 2.377, 領域排名: 17, 領域期刊數: 83, 領域排名: 20.48%)

Polymorphisms in Kallikrein7 and 10 genes and oral cancer risks in Taiwan betel quid chewers and smokers.
Wang YY, Lin YC, Hung HC, Tien WY, Shieh TY. - - 1 - Oral Diseases - Oral Dis 2013;19(8):824-832
(IF: 2.377, Journal Ranking: 17, Number of Journals of this Field: 83, Ranking: 20.48%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
114 — N 國科會(原科技部) — NSTC112-2314-B-037-112-MY3 — 1 個人型
探究檳榔誘導的纖維母細胞轉化及衰老如何促進口腔惡變(3/3)( )
2025/08/01 ~ 2026/07/31
2
113 — N 國科會(原科技部) — NSTC112-2314-B-037-112-MY3 — 1 個人型
探究檳榔誘導的纖維母細胞轉化及衰老如何促進口腔惡變(2/3)( )
2024/08/01 ~ 2026/07/31
3
113 — NK 高醫-中山合作計畫 — NK113P23 — 1 個人型
老藥新用策略於口腔癌前病變的應用(Application of old drug re-purposing strategy in oral precancerous lesions)
2024/01/01 ~ 2024/12/31
4
112 — DK 前瞻重點(原校院) — KMU-DK(A)113002 —  
探討上皮生長因子於免疫調節的分子機制及在口腔癌前病變進展的角色( )
2024/01/01 ~ 2024/12/31
5
112 — N 國科會(原科技部) — NSTC112-2314-B-037-112-MY3 — 1 個人型
探究檳榔誘導的纖維母細胞轉化及衰老如何促進口腔惡變(1/3)( )
2023/08/01 ~ 2026/07/31
6
112 — NK 高醫-中山合作計畫 —   — 1 個人型
探討IL-17RB在口腔癌進展所扮演的角色(Role of IL-17RB in oral cancer progression)
2023/01/01 ~ 2023/12/31
7
111 — DK 前瞻重點(原校院) — KMU-DK(A)112006 — 1 個人型
細胞衰老與DNA修復受損的交互作用在口腔癌化的角色及新穎治療的開發( )
2023/01/01 ~ 2023/12/31
8
111 — N 國科會(原科技部) — MOST111-2314-B-037-046 — 1 個人型
巨噬細胞的M2極化和代謝重編程影響檳榔子萃取物所誘發之口腔潛在惡性疾病的癌化( )
2022/08/01 ~ 2023/07/31
9
111 — NK 高醫-中山合作計畫 —   — 1 個人型
探討RAD51在口腔癌治療抗性中扮演的角色(Role of RAD51 for treatment resistance in oral cancer)
2022/01/01 ~ 2022/12/31
10
111 — Z 大專學生研究計畫及博士後 — NSTC112-2813-C-037-046-B — 8 大專學生研究計畫
112年度大專學生研究計畫-蘇文禎(牙醫4)( )
2023/07/01 ~ 2024/02/29
11
110 — DK 前瞻重點(原校院) — KMU-DK(A)111005 —  
Elucidation of pathologic mechanisms underlying areca nut extracts-promoted oral cancer progression via M2 macrophage-secreted VCAM-1( )
2022/01/01 ~ 2022/12/31
12
110 — N 國科會(原科技部) — MOST110-2314-B-037-058 — 1 個人型
IL-1RA如何藉由調控癌細胞幹性與腫瘤微環境來影響口腔癌的治療抗性( )
2021/08/01 ~ 2022/07/31
13
109 — KP 高醫屏科大 — NPUST-KMU-109-P008 — 1 個人型
探討陽極處理的Ti-7.5Mo合金對小鼠骨髓間質細胞骨分化影響( )
2020/01/01 ~ 2020/12/31
14
109 — M 高醫(種子計畫) — KMU-M110003 —  
IL-1RA如何藉由調控癌細胞幹性與腫瘤微環境來影響口腔癌的治療抗性( )
2021/01/01 ~ 2021/12/31
15
109 — NK 高醫-中山合作計畫 — NSYSUKMU109-I004-3 — 2 整合型
Explore how ANE influence oral tissue fibroblasts to promote the initiation and progression of oral cancer( )
2020/01/01 ~ 2020/12/31
16
108 — N 國科會(原科技部) — MOST108-2314-B-037-014 — 1 個人型
DSB修復核酸分解酵素MRE11在口腔癌中的探討( )
2019/08/01 ~ 2020/07/31
17
108 — NK 高醫-中山合作計畫 — NSYSUKMU108-P033 —  
探討MRE11透過下游CD44在口腔癌轉移過程中扮演的角色( )
2019/01/01 ~ 2019/12/31
18
107 — NK 高醫-中山合作計畫 — NSYSUKMU107-P019 — 1 個人型
探討Interleukin-1 receptor antagonist (IL1RN)在口腔癌轉移過程中扮演的角色( )
2018/01/01 ~ 2018/12/31
19
107 — Q 新聘教師計畫(校內) — KMU-Q108019 —  
MAL 光動力治療誘導口腔癌細胞走向凋亡( )
2019/01/01 ~ 2019/12/31
20
106 — N 國科會(原科技部) — MOST107-2314-B-037-007 — 1 個人型
探討DNA修復蛋白MRE11在口腔癌轉移過程中扮演的角色( )
2018/01/01 ~ 2018/10/31
21
106 — Q 新聘教師計畫(校內) — KMU-Q107010 —  
細胞自噬在光動力療法治療口腔癌前病變上所扮演的角色( )
2018/01/01 ~ 2018/12/31
22
106 — Z 大專學生研究計畫及博士後 — MOST107-2813-C-037-049-B — 8 大專學生研究計畫
107年度大專學生研究計畫-劉磬(口衛2)( )
2018/07/01 ~ 2019/02/28

 Patent

NO Patent Name Country Certified Date Patent No
1 光敏劑或其前驅藥物的醫藥載體 中華民國 2019/04/21 I656883