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 Education

School — Major — Degree Duration

國立中央大學 — 統計研究所(畢) — 博士

PhD,  ,  

1999/09 — 2005/06

國立成功大學 — 統計學系(畢) — 碩士

Master,  ,  

1997/09 — 1999/06

淡江大學 — 統計學系(畢) — 學士

Bachelor,  ,  

1995/09 — 1997/06

 Intramural Experience

Office/Department/Institute Position Duration
基礎科學教育中心 Center for Fundamental Science   Associate Professor 2021/08/01 —  
基礎科學教育中心 Center for Fundamental Science   Assistant Professor 2017/02/01 — 2021/07/31
基礎科學教育中心 Center for Fundamental Science   Assistant Professor 2016/08/01 — 2017/01/31

 Extramural Experience

 

 Discipline

 

 Research & Technology Platform Open to the Outside

 

 Interested Area(s)for Interdisciplinary Research

 

 

 Area(s) of Expertise & Research

強韌迴歸、貝氏統計、遺傳流病

 

 Publication

NO Publication
1

Associating Multivariate Traits with Genetic Variants Using Collapsing and Kernel Methods with Pedigree- or Population-Based Studies.
簡莉珠* - - 1 - COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE - COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE 2021 2021卷(-期):8812282頁
(IF: 2.809, 領域排名: 26, 領域期刊數: 57, 領域排名: 45.61%)

Associating Multivariate Traits with Genetic Variants Using Collapsing and Kernel Methods with Pedigree- or Population-Based Studies.
Li-Chu Chien* - - 1 - COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE - COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE 2021;2021(-):8812282
(IF: 2.809, Journal Ranking: 26, Number of Journals of this Field: 57, Ranking: 45.61%)

2

A rank-based normalization method with the fully adjusted full-stage procedure in genetic association studies
簡莉珠 - - 1 - PLoS ONE - PLOS ONE 2020 15卷(6期):e0233847頁
(IF: 3.24, 領域排名: 26, 領域期刊數: 73, 領域排名: 35.62%)

A rank-based normalization method with the fully adjusted full-stage procedure in genetic association studies
Li-Chu Chien - - 1 - PLoS ONE - PLOS ONE 2020;15(6):e0233847
(IF: 3.24, Journal Ranking: 26, Number of Journals of this Field: 73, Ranking: 35.62%)

3

Combining dependent p-values by gamma distributions
簡莉珠 - - 1 - Statistical Applications in Genetics and Molecular Biology - STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY 2020 19卷(4-6期):20190057頁
(IF: 0.419, 領域排名: 123, 領域期刊數: 125, 領域排名: 98.40%)

Combining dependent p-values by gamma distributions
Li-Chu Chien - - 1 - Statistical Applications in Genetics and Molecular Biology - STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY 2020;19(4-6):20190057
(IF: 0.419, Journal Ranking: 123, Number of Journals of this Field: 125, Ranking: 98.40%)

4

A method for combining p-values in meta-analysis by gamma distributions
簡莉珠* - - 1 - Journal of Applied Statistics - JOURNAL OF APPLIED STATISTICS 2019 46卷(2期):247-261頁
(IF: 1.031, 領域排名: 68, 領域期刊數: 124, 領域排名: 54.84%)

A method for combining p-values in meta-analysis by gamma distributions
Li-Chu Chien* - - 1 - Journal of Applied Statistics - JOURNAL OF APPLIED STATISTICS 2019;46(2):247-261
(IF: 1.031, Journal Ranking: 68, Number of Journals of this Field: 124, Ranking: 54.84%)

5

A flexible Bayesian non-parametric approach for fitting the odds to case II interval-censored data
Yuh-Jenn Wu, Wei-Quan Fang, Li-Hsueh Chenga, Kai-Chi Chu, Yin-Tzer Shih, Li-Chu Chien* - - 1 - JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION - JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION 2018 88卷(16期):3132–3150頁
(IF: 0.767, 領域排名: 84, 領域期刊數: 123, 領域排名: 68.29%)

A flexible Bayesian non-parametric approach for fitting the odds to case II interval-censored data
Yuh-Jenn Wu, Wei-Quan Fang, Li-Hsueh Chenga, Kai-Chi Chu, Yin-Tzer Shih, Li-Chu Chien* - - 1 - JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION - JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION 2018;88(16):3132–3150
(IF: 0.767, Journal Ranking: 84, Number of Journals of this Field: 123, Ranking: 68.29%)

6

General retrospective mega‐analysis framework for rare variant association tests
Li‐Chu Chien, Yen‐Feng Chiu - - 1 - Genetic Epidemiology - GENETIC EPIDEMIOLOGY 2018 42卷(7期):621–635頁
(IF: 2.5, 領域排名: 10, 領域期刊數: 59, 領域排名: 16.95%)

General retrospective mega‐analysis framework for rare variant association tests
Li‐Chu Chien, Yen‐Feng Chiu - - 1 - Genetic Epidemiology - GENETIC EPIDEMIOLOGY 2018;42(7):621–635
(IF: 2.5, Journal Ranking: 10, Number of Journals of this Field: 59, Ranking: 16.95%)

7

Region-based association tests for sequencing data on survival traits
Li-Chu Chien, Donald W. Bowden, Yen‐Feng Chiu - - 1 - Genetic Epidemiology - GENETIC EPIDEMIOLOGY 2017 41卷(6期):511-522頁
(IF: 2.544, 領域排名: 9, 領域期刊數: 59, 領域排名: 15.25%)

Region-based association tests for sequencing data on survival traits
Li-Chu Chien, Donald W. Bowden, Yen‐Feng Chiu - - 1 - Genetic Epidemiology - GENETIC EPIDEMIOLOGY 2017;41(6):511-522
(IF: 2.544, Journal Ranking: 9, Number of Journals of this Field: 59, Ranking: 15.25%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
112 — N 國科會(原科技部) — NSTC112-2118-M-037-001 — 1 個人型
存在水平多效性兩個性狀因果關係檢測方法( )
2023/08/01 ~ 2024/07/31
2
111 — N 國科會(原科技部) — MOST110-2118-M-037-001-MY2 — 1 個人型
有序特徵與遺傳變異關聯性檢測方法(2/2)( )
2022/08/01 ~ 2023/10/31
3
110 — N 國科會(原科技部) — MOST110-2118-M-037-001-MY2 — 1 個人型
有序特徵與遺傳變異關聯性檢測方法(1/2)( )
2021/08/01 ~ 2023/10/31
4
109 — N 國科會(原科技部) — MOST108-2118-M-037-001-MY2 — 1 個人型
分析譜系或群體結構化資料多變量特徵與多種遺傳變異關聯性檢測方法(2/2)( )
2020/08/01 ~ 2021/10/31
5
108 — N 國科會(原科技部) — MOST108-2118-M-037-001-MY2 — 1 個人型
分析譜系或群體結構化資料多變量特徵與多種遺傳變異關聯性檢測方法(1/2)( )
2019/08/01 ~ 2021/10/31
6
107 — N 國科會(原科技部) — MOST107-2118-M-037-001 — 1 個人型
一個檢測罕見遺傳變異與疾病關聯性的穩健有效檢測方法( )
2018/08/01 ~ 2019/10/31
7
105 — N 國科會(原科技部) — MOST106-2118-M-037-001 — 1 個人型
廣義罕見遺傳變異巨量整合分析檢測方法( )
2017/05/01 ~ 2018/10/31

 Patent