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 Education

School — Major — Degree Duration

高雄醫學大學 — 醫學研究所(畢) — 博士

Doctorate,  ,  

2006/09 — 2014/01

高雄醫學大學 — 醫學研究所(畢) — 碩士

Master,  ,  

2000/09 — 2003/01

國立成功大學 — 醫事技術學系(畢) — 學士

Bachelor,  ,  

1990/09 — 1994/06

 Intramural Experience

Office/Department/Institute Position Duration
檢驗醫學部 Department of Laboratory Medicine   Medical Technologist   —  
醫學檢驗生物技術學系碩士班 Master's Program in Medical Laboratory and Biotechnology   Director 2023/08/01 — 2024/07/31
醫學檢驗生物技術學系博士班 PhD Program in Medical Laboratory and Biotechnology   Director 2023/08/01 — 2024/07/31
醫學檢驗生物技術學系 Department of Medical Laboratory Science and Biotechnology   Chair 2021/08/01 — 2024/07/31
醫學檢驗生物技術學系 Department of Medical Laboratory Science and Biotechnology   Professor 2021/02/01 —  
醫學檢驗生物技術學系 Department of Medical Laboratory Science and Biotechnology   Associate Professor 2018/02/01 — 2021/01/31
醫學檢驗生物技術學系 Department of Medical Laboratory Science and Biotechnology   Assistant Professor 2014/08/01 — 2018/01/31
醫學檢驗生物技術學系 Department of Medical Laboratory Science and Biotechnology   Teacher 2011/08/01 — 2013/07/31

 Extramural Experience

 

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 寄生蟲學、醫事技術及實驗診斷 Parasitology, Medical Technology and Laboratory Diagnostics
2 生物醫農類 Biology, Medicine and Agriculture 心胸內科 Division of Cardiothoracic Medicine

 Research & Technology Platform Open to the Outside

Liquid chromatography (FPLC by BioRad; UPLC by WATERS), Mass spectrometry (LC/MSE by WATERS), Proteomic analysis (Progenesis QI for proteomics), Protein post-translational modification (ProteinLynx Global SERVER), Lipidomics (Progenesis QI).

 Interested Area(s)for Interdisciplinary Research

Biotechnology, Glycobiology, Biochemistry, Lipid metabolism, Molecular biology

Biotechnology, Glycobiology, Biochemistry, Lipid metabolism, Molecular biology

 Area(s) of Expertise & Research

脂質體學、脂質代謝、分子生物學、病毒學

Lipidomics, Lipid Metabolism, Molecular Biology, Virology

 Publication

NO Publication
1

Elucidating the Implications of Norovirus - and -Glycosylation, -GlcNAcylation, and Phosphorylation.
程家琪, 柯冠銘, 褚佩瑜*, 柯良胤* - - 1 - Viruses-Basel - VIRUSES-BASEL 2023 15卷(3期):798頁
(IF: 5.818, 領域排名: 14, 領域期刊數: 37, 領域排名: 37.84%)

Elucidating the Implications of Norovirus - and -Glycosylation, -GlcNAcylation, and Phosphorylation.
Chia-Chi Cheng, Guan-Ming Ke, Pei-Yu Chu, Liang-Yin Ke - - 1 - Viruses-Basel - VIRUSES-BASEL 2023;15(3):798
(IF: 5.818, Journal Ranking: 14, Number of Journals of this Field: 37, Ranking: 37.84%)

2

Untargeted Lipidomic Profiling Reveals Lysophosphatidylcholine and Ceramide as Atherosclerotic Risk Factors in Knockout Mice.
劉思慧, 詹華蓁, Guan-Ming Ke, Swetha Kamatam, Gopal Kedihithlu Marathe, 庫碼, 柯良胤* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 24卷(8期):6956頁
(IF: 5.6, 領域排名: 66, 領域期刊數: 285, 領域排名: 23.16%)

Untargeted Lipidomic Profiling Reveals Lysophosphatidylcholine and Ceramide as Atherosclerotic Risk Factors in Knockout Mice.
Shi Hui Law, Hua-Chen Chan, Guan-Ming Ke, Swetha Kamatam, Gopal Kedihithlu Marathe, Vinoth Kumar Ponnusamy, Liang-Yin Ke - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023;24(8):6956
(IF: 5.6, Journal Ranking: 66, Number of Journals of this Field: 285, Ranking: 23.16%)

3

Advanced Detection Method for Dengue NS1 Protein Using Ultrasensitive ELISA with Thio-NAD Cycling
Po-Kai Chen,Jyun-Hao Chang,柯良胤,Jun-Kai Kao,Chang-Hua Chen,Rei-Cheng Yang,Teruki Yoshimura,Etsuro Ito*,蔡季君* - - 1 - VIRUSES-BASEL - VIRUSES-BASEL 2023 15卷(9期):1894頁
(IF: 4.7, 領域排名: 15, 領域期刊數: 36, 領域排名: 41.67%)

Advanced Detection Method for Dengue NS1 Protein Using Ultrasensitive ELISA with Thio-NAD Cycling
Po-Kai Chen,Jyun-Hao Chang ,Liang-Yin Ke ,Jun-Kai Kao,Chang-Hua Chen,Rei-Cheng Yang ,Teruki Yoshimura ,Etsuro Ito*,Jih-Jin Tsai* - - 1 - VIRUSES-BASEL - VIRUSES-BASEL 2023;15(9):1894
(IF: 4.7, Journal Ranking: 15, Number of Journals of this Field: 36, Ranking: 41.67%)

4

Trajectory in biological metal-organic frameworks: Biosensing and sustainable strategies-perspectives and challenges.
Uday Shashikumar, Somi Joshi, Ananya Srivastava, 蔡沛倩, Kandkuri Dhana Sai Shree, Meera Suresh, Balasubramani Ravindran, Chaudhery Mustansar Hussain, Shashi Chawla*, 柯良胤*, 庫碼* - - 1 - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023 253卷(Pt 6期):127120頁
(IF: 8.2, 領域排名: 5, 領域期刊數: 86, 領域排名: 5.81%)

Trajectory in biological metal-organic frameworks: Biosensing and sustainable strategies-perspectives and challenges.
Uday Shashikumar, Somi Joshi, Ananya Srivastava, Pei-Chien Tsai, Kandkuri Dhana Sai Shree, Meera Suresh, Balasubramani Ravindran, Chaudhery Mustansar Hussain, Shashi Chawla*, Liang-Yin Ke*, Vinoth Kumar Ponnusamy** - - 1 - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023;253(Pt 6):127120
(IF: 8.2, Journal Ranking: 5, Number of Journals of this Field: 86, Ranking: 5.81%)

5

The critical role of galectin-12 in modulating lipid metabolism in sebaceous glands
Tsao CH, Hsieh WC, Lin FJ, Yang RY, Chang MT, Apaya MK, Shyur LF, 柯良胤, Zouboulis CC, Liu FT - - 1 - J Invest Dermatol - JOURNAL OF INVESTIGATIVE DERMATOLOGY 2023 143卷(6期):913-924.e4頁
(IF: 6.5, 領域排名: 6, 領域期刊數: 70, 領域排名: 8.57%)

The critical role of galectin-12 in modulating lipid metabolism in sebaceous glands
Tsao CH, Hsieh WC, Lin FJ, Yang RY, Chang MT, Apaya MK, Shyur LF, Ke LY, Zouboulis CC, Liu FT - - 1 - J Invest Dermatol - JOURNAL OF INVESTIGATIVE DERMATOLOGY 2023;143(6):913-924.e4
(IF: 6.5, Journal Ranking: 6, Number of Journals of this Field: 70, Ranking: 8.57%)

6

SPECT/CT imaging for tracking subendothelial retention of electronegative low-density lipoprotein in vivo
劉思慧, 柯建志, 朱志生, Liu SH, Weng MC, 柯良胤*, 詹華蓁* - - 1 - Int J Biol Macromol - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023 2卷(250期):126069頁
(IF: 8.2, 領域排名: 5, 領域期刊數: 86, 領域排名: 5.81%)

SPECT/CT imaging for tracking subendothelial retention of electronegative low-density lipoprotein in vivo
Law SH, Ke CC, Chu CS, Liu SH, Weng MC, Ke LY*, Chan HC* - - 1 - Int J Biol Macromol - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023;2(250):126069
(IF: 8.2, Journal Ranking: 5, Number of Journals of this Field: 86, Ranking: 5.81%)

7

Increased risk of chronic fatigue syndrome following infection: a 17-year population-based cohort study
Chang H, Kuo CF, Yu TS, 柯良胤, Hung CL, Tsai SY - - 1 - J Transl Med - JOURNAL OF TRANSLATIONAL MEDICINE 2023 21卷(1期):804頁
(IF: 7.4, 領域排名: 29, 領域期刊數: 136, 領域排名: 21.32%)

Increased risk of chronic fatigue syndrome following infection: a 17-year population-based cohort study
Chang H, Kuo CF, Yu TS, Ke LY, Hung CL, Tsai SY - - 1 - J Transl Med - JOURNAL OF TRANSLATIONAL MEDICINE 2023;21(1):804
(IF: 7.4, Journal Ranking: 29, Number of Journals of this Field: 136, Ranking: 21.32%)

8

Galectin-12 modulates sebocyte proliferation and cell cycle progression by regulating cyclin A1 and CDK2.
曹經漢, Hsieh WC, Lin FJ, Yang RY, Chang MT, Apaya MK, Shyur LF, 柯良胤, Zouboulis CC, 劉扶東* - - 1 - GLYCOBIOLOGY - GLYCOBIOLOGY 2022 32卷(1期):73-82頁
(IF: 5.954, 領域排名: 76, 領域期刊數: 297, 領域排名: 25.59%)

Galectin-12 modulates sebocyte proliferation and cell cycle progression by regulating cyclin A1 and CDK2.
Ching-Han Tsao, Wei-Chen Hsieh, Ri-Yao Yang, Yuan-Hsin Lo, Ting-Jui Tu, Liang-Yin Ke, Christos C Zouboulis, Fu-Tong Liu* - - 1 - GLYCOBIOLOGY - GLYCOBIOLOGY 2022;32(1):73-82
(IF: 5.954, Journal Ranking: 76, Number of Journals of this Field: 297, Ranking: 25.59%)

9

陰電性極低密度脂蛋白誘發小鼠腦部發炎和認知功能障礙
林盈劭, 劉景寬#, 李香君, 周美鵑, 柯良胤, 陳珠璜, 陳秀蘭* - - 1 - Scientific Reports - SCIENTIFIC REPORTS 2021 11卷(1期):6103頁
(IF: 4.996, 領域排名: 19, 領域期刊數: 73, 領域排名: 26.03%)

Electronegative very-low-density lipoprotein induces brain inflammation and cognitive dysfunction in mice
Ying-Shao Lin, Ching-Kuan Liu#, Hsiang-Chun Lee, Mei-Chuan Chou, Liang-Yin Ke, Chu-Huang Chen, Shiou-Lan Chen*. - - 1 - Scientific Reports - SCIENTIFIC REPORTS 2021;11(1):6103
(IF: 4.996, Journal Ranking: 19, Number of Journals of this Field: 73, Ranking: 26.03%)

10

基於質譜的系統用於識別和分型諾如病毒主要衣殼蛋白 VP1
褚佩瑜, Hui-Wen Huang#, Michittra Boonchan, 田育彰, Kevin Leroy Louis, 李昆畝, Kazushi Motomura*, 柯良胤* - - 1 - Viruses - VIRUSES-BASEL 2021 13卷(11期):2332頁
(IF: 5.818, 領域排名: 14, 領域期刊數: 37, 領域排名: 37.84%)

Mass Spectrometry-Based System for Identifying and Typing Norovirus Major Capsid Protein VP1
Pei-Yu Chu , Hui-Wen Huang#, Michittra Boonchan, Yu-Chang Tyan, Kevin Leroy Louis, Kun-Mu Lee, Kazushi Motomura*, Liang-Yin Ke* - - 1 - Viruses - VIRUSES-BASEL 2021;13(11):2332
(IF: 5.818, Journal Ranking: 14, Number of Journals of this Field: 37, Ranking: 37.84%)

11

Efficiency comparison of PGBR extract and γ-oryzanol in antioxidative stress and anti-inflammatory properties against metabolic syndrome
林慧麗, Lin SH, 沈國屏, 詹華蓁, Tseng YH, 顏學偉, 劉思慧, 柯良胤* - - 1 - Journal of Food Biochemistry - JOURNAL OF FOOD BIOCHEMISTRY 2020 44卷(2期):e13129頁
(IF: 2.72, 領域排名: 73, 領域期刊數: 144, 領域排名: 50.69%)

Efficiency comparison of PGBR extract and γ-oryzanol in antioxidative stress and anti-inflammatory properties against metabolic syndrome
Lin HL, Lin SH, Shen KP, Chan HC, Tseng YH, Yen HW, Law SH, Ke LY* - - 1 - Journal of Food Biochemistry - JOURNAL OF FOOD BIOCHEMISTRY 2020;44(2):e13129
(IF: 2.72, Journal Ranking: 73, Number of Journals of this Field: 144, Ranking: 50.69%)

12

Role of low-density lipoprotein in early vascular aging associated with systemic lupus erythematosus
詹華蓁, 詹秀娟, 梁展榮, 李香君, 蘇鴻, 李安生, 謝建台, 蔡文展, 歐燦騰, 吳正欽, 朱志生, Dixon RA, 柯良胤*, 顏正賢*, 陳珠璜* - - 1 - Arthritis Rheumatol - ARTHRITIS & RHEUMATOLOGY 2020 72卷(6期):972-984頁
(IF: 9.586, 領域排名: 3, 領域期刊數: 32, 領域排名: 9.38%)

Role of low-density lipoprotein in early vascular aging associated with systemic lupus erythematosus
Chan HC, Chan HCB, Liang CJ, Lee HC, Su H, Lee AS, Shiea J, Tsai WC, Ou TT, Wu CC, Chu CS, Dixon RA, Ke LY*, Yen JH*, Chen CH* - - 1 - Arthritis Rheumatol - ARTHRITIS & RHEUMATOLOGY 2020;72(6):972-984
(IF: 9.586, Journal Ranking: 3, Number of Journals of this Field: 32, Ranking: 9.38%)

13

Identifying the Therapeutic Significance of Mesenchymal Stem Cells
Mishra VK, Shih HH#, Parveen F, Lenzen D, Ito E, 詹德富*, 柯良胤* - - 1 - Cells - CELLS 2020 9卷(5期):1145頁
(IF: 6.6, 領域排名: 53, 領域期刊數: 195, 領域排名: 27.18%)

Identifying the Therapeutic Significance of Mesenchymal Stem Cells
Mishra VK, Shih HH#, Parveen F, Lenzen D, Ito E, Chan TF*, Ke LY* - - 1 - Cells - CELLS 2020;9(5):1145
(IF: 6.6, Journal Ranking: 53, Number of Journals of this Field: 195, Ranking: 27.18%)

14

Increased APOE glycosylation plays a key role in the atherogenicity of L5 low-density lipoprotein
柯良胤*, 詹華蓁, 陳志杰, 張權發, 盧柏樑, 朱志生, 賴文德, 辛錫璋, 劉扶東, 陳珠璜* - - 1 - FASEB J - FASEB JOURNAL 2020 34卷(7期):9802-9813頁
(IF: 5.191, 領域排名: 14, 領域期刊數: 93, 領域排名: 15.05%)

Increased APOE glycosylation plays a key role in the atherogenicity of L5 low-density lipoprotein
Ke LY*, Chan HC, Chen CC, Chang CF, Lu PL, Chu CS, Lai WT, Shin SJ, Liu FT, Chen CH* - - 1 - FASEB J - FASEB JOURNAL 2020;34(7):9802-9813
(IF: 5.191, Journal Ranking: 14, Number of Journals of this Field: 93, Ranking: 15.05%)

15

Effect of acyl and alkyl analogs of platelet-activating factor on inflammatory signaling
Marathe GK*, Chaithra VH, 柯良胤, Chen CH - - 1 - Prostaglandins Other Lipid Mediat - PROSTAGLANDINS & OTHER LIPID MEDIATORS 2020 151卷(-期):106478頁
(IF: 3.072, 領域排名: 195, 領域期刊數: 298, 領域排名: 65.44%)

Effect of acyl and alkyl analogs of platelet-activating factor on inflammatory signaling
Marathe GK*, Chaithra VH, Ke LY, Chen CH - - 1 - Prostaglandins Other Lipid Mediat - PROSTAGLANDINS & OTHER LIPID MEDIATORS 2020;151(-):106478
(IF: 3.072, Journal Ranking: 195, Number of Journals of this Field: 298, Ranking: 65.44%)

16

Clinical significance of electronegative low-density lipoprotein cholesterol in atherothrombosis
朱志生, 劉思慧, Lenzen D, 陳泳虹, 翁世峰, Ito E, Wu JC, Chen CH, 詹華蓁*, 柯良胤* - - 1 - Biomedicines - BIOMEDICINES 2020 8卷(8期):254頁
(IF: 4.717, 領域排名: 30, 領域期刊數: 139, 領域排名: 21.58%)

Clinical significance of electronegative low-density lipoprotein cholesterol in atherothrombosis
Chu CS, Law SH, Lenzen D, Tan YH, Weng SF, Ito E, Wu JC, Chen CH, Chan HC*, Ke LY* - - 1 - Biomedicines - BIOMEDICINES 2020;8(8):254
(IF: 4.717, Journal Ranking: 30, Number of Journals of this Field: 139, Ranking: 21.58%)

17

餐後極低密度脂蛋白在代謝症候群之心房重構發展中的作用
李香君*, 辛錫璋, 黃日楷, 林明諺, 林郁珣, 柯良胤, 姜和均, 蔡維中, 趙敏芳, 林逸翔 - - 1 - Lipids in Health and Disease - LIPIDS IN HEALTH AND DISEASE 2020 19卷(1期):210頁
(IF: 2.906, 領域排名: 47, 領域期刊數: 89, 領域排名: 52.81%)

The role of postprandial very-low-density lipoprotein in the development of atrial remodeling in metabolic syndrome
Hsiang-Chun Lee*, Shyi-Jang Shin, Jih-Kai Huang, Ming-Yen Lin, Yu-Hsun Lin, Liang-Yin Ke, He-Jiun Jiang, Wei-Chung Tsai, Min-Fang Chao, Yi-Hsiung Lin - - 1 - Lipids in Health and Disease - LIPIDS IN HEALTH AND DISEASE 2020;19(1):210
(IF: 2.906, Journal Ranking: 47, Number of Journals of this Field: 89, Ranking: 52.81%)

18

Disruption of Retinoid Homeostasis Induces RBP4 Overproduction in Diabetes: O-GlcNAcylation Involved.
辛錫璋, 陳肇閎, 郭汶甄, 詹華蓁, 詹秀娟, 林昆德, 柯良胤* - - 1 - Metabolism: clinical and experimental - METABOLISM-CLINICAL AND EXPERIMENTAL 2020 113卷(-期):154403頁
(IF: 8.694, 領域排名: 13, 領域期刊數: 145, 領域排名: 8.97%)

Disruption of Retinoid Homeostasis Induces RBP4 Overproduction in Diabetes: O-GlcNAcylation Involved.
Shyi-Jang Shin, Chao-Hung Chen, Wen-Chen Kuo, Hua-Chen Chan, Hsiu-Chuan Chan, Kun-Der Lin, Liang-Yin Ke* - - 1 - Metabolism: clinical and experimental - METABOLISM-CLINICAL AND EXPERIMENTAL 2020;113(-):154403
(IF: 8.694, Journal Ranking: 13, Number of Journals of this Field: 145, Ranking: 8.97%)

19

Extract of pre-germinated brown rice protects against cardiovascular dysfunction by reducing levels of inflammation and free radicals in a rat model of type II diabetes
Liang HL, Cheng PW, Lin HL, Hao CL, 柯良胤, Chou HY, Tseng YH, 顏學偉, Shen KP* - - 1 - Journal of Functional Foods - JOURNAL OF FUNCTIONAL FOODS 2020 75卷(-期):104218頁
(IF: 4.451, 領域排名: 35, 領域期刊數: 144, 領域排名: 24.31%)

Extract of pre-germinated brown rice protects against cardiovascular dysfunction by reducing levels of inflammation and free radicals in a rat model of type II diabetes
Liang HL, Cheng PW, Lin HL, Hao CL, Ke LY, Chou HY, Tseng YH, Yen HW, Shen KP* - - 1 - Journal of Functional Foods - JOURNAL OF FUNCTIONAL FOODS 2020;75(-):104218
(IF: 4.451, Journal Ranking: 35, Number of Journals of this Field: 144, Ranking: 24.31%)

20

An increased plasma level of apoCIII-rich electronegative high-density lipoprotein may contribute to cognitive impairment in Alzheimer’s disease
詹華蓁, 柯良胤#, 盧筱婷, 翁世峰, 詹秀娟, 劉思慧, 林怡伶, 張權發, 盧怡旭, Chen CH, 朱志生* - - 1 - Biomedicines - BIOMEDICINES 2020 8卷(12期):542頁
(IF: 4.717, 領域排名: 30, 領域期刊數: 139, 領域排名: 21.58%)

An increased plasma level of apoCIII-rich electronegative high-density lipoprotein may contribute to cognitive impairment in Alzheimer’s disease
Chan HC, Ke LY#, Lu HT, Weng SF, Chan HCB, Law SH, Lin IL, Chang CF, Lu YH, Chen CH, Chu CS* - - 1 - Biomedicines - BIOMEDICINES 2020;8(12):542
(IF: 4.717, Journal Ranking: 30, Number of Journals of this Field: 139, Ranking: 21.58%)

21

Molecular and cellular mechanisms of electronegative lipoproteins in cardiovascular diseases
柯良胤, 劉思慧#, Mishra VK, Parveen F, 詹華蓁, 盧怡旭, 朱志生* - - 1 - Biomedicines - BIOMEDICINES 2020 8卷(12期):550頁
(IF: 4.717, 領域排名: 30, 領域期刊數: 139, 領域排名: 21.58%)

Molecular and cellular mechanisms of electronegative lipoproteins in cardiovascular diseases
Ke LY, Law SH#, Mishra VK, Parveen F, Chan HC, Lu YH, Chu CS* - - 1 - Biomedicines - BIOMEDICINES 2020;8(12):550
(IF: 4.717, Journal Ranking: 30, Number of Journals of this Field: 139, Ranking: 21.58%)

22

Electronegative low-density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta through disruption of the stimulated by retinoic acid 6 cascade.
陳肇閎, 柯良胤, 詹華蓁, 朱志生, 李安生, 林昆德, 李美月, 蕭璧容, 陳珠璜, 辛錫璋* - - 1 - Journal of diabetes investigation - JOURNAL OF DIABETES INVESTIGATION 2020 11卷(3期):535-544頁
(IF: 4.232, 領域排名: 64, 領域期刊數: 145, 領域排名: 44.14%)

Electronegative low-density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta through disruption of the stimulated by retinoic acid 6 cascade.
Chao-Hung Chen, Liang-Yin Ke, Hua-Chen Chan, Chih-Sheng Chu, An-Sheng Lee, Kun-Der Lin, Mei-Yueh Lee, Pi-Jung Hsiao, Chu-Huang Chen, Shyi-Jang Shin* - - 1 - Journal of diabetes investigation - JOURNAL OF DIABETES INVESTIGATION 2020;11(3):535-544
(IF: 4.232, Journal Ranking: 64, Number of Journals of this Field: 145, Ranking: 44.14%)

23

Pre‐germinated brown rice extract ameliorates high‐fat diet‐induced metabolic syndrome
Chi‐Long Hao, 林慧麗, 柯良胤, Hsueh‐Wei Yen, 沈國屏* - - 1 - Journal of Food Biochemistry - JOURNAL OF FOOD BIOCHEMISTRY 2019 43卷(3期):e12769頁
(IF: 1.662, 領域排名: 85, 領域期刊數: 139, 領域排名: 61.15%)

Pre‐germinated brown rice extract ameliorates high‐fat diet‐induced metabolic syndrome
Hao CL, Lin HL, Ke LY Yen HW, Shen KP*. - - 1 - Journal of Food Biochemistry - JOURNAL OF FOOD BIOCHEMISTRY 2019;43(3):e12769
(IF: 1.662, Journal Ranking: 85, Number of Journals of this Field: 139, Ranking: 61.15%)

24

Flavonoids from Camellia sinensis (L.) O. Kuntze seed ameliorates TNF-a induced insulin resistance in HepG2 cells
Fu-Chih Chen, 沈國屏, 柯良胤, 林慧麗, Chia-Chang Wu, Shyh-Yu Shaw* - - 1 - Saudi Pharmaceutical Journal - SAUDI PHARMACEUTICAL JOURNAL 2019 27卷(4期):507-516頁
(IF: 2.879, 領域排名: 120, 領域期刊數: 270, 領域排名: 44.44%)

Flavonoids from Camellia sinensis (L.) O. Kuntze seed ameliorates TNF-a induced insulin resistance in HepG2 cells
Chen FC, Shen KP, Ke LY, Lin HL, Wu CC, Shaw SU* - - 1 - Saudi Pharmaceutical Journal - SAUDI PHARMACEUTICAL JOURNAL 2019;27(4):507-516
(IF: 2.879, Journal Ranking: 120, Number of Journals of this Field: 270, Ranking: 44.44%)

25

An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases
劉思慧, Mei-Lin Chan#, Gopal K. Marathe, Farzana Parveen, 陳珠璜, 柯良胤* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019 20卷(5期):1149頁
(IF: 4.556, 領域排名: 74, 領域期刊數: 297, 領域排名: 24.92%)

An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases
Law SH, Chan ML#, Marathe GK, Parveen F, Chen CH, Ke LY*. - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019;20(5):1149
(IF: 4.556, Journal Ranking: 74, Number of Journals of this Field: 297, Ranking: 24.92%)

26

O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes.
陳肇閎, 林坤德, 柯良胤, Liang CJ, Kuo WC, 李美月, 李宇力, 蕭璧容, 許志成, 辛錫璋* - - 1 - Biochimica Et Biophysica Acta-General Subjects - BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 2019 1863卷(6期):1059-1069頁
(IF: 3.422, 領域排名: 19, 領域期刊數: 71, 領域排名: 26.76%)

O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes.
Chen CH, Lin KD, Ke LY, Liang CJ, Kuo WC, Lee MY, Lee YL, Hsiao PJ, Hsu CC, Shin SJ* - - 1 - Biochimica Et Biophysica Acta-General Subjects - BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 2019;1863(6):1059-1069
(IF: 3.422, Journal Ranking: 19, Number of Journals of this Field: 71, Ranking: 26.76%)

27

Urinary Adiponectin as A New Diagnostic Index for Chronic Kidney Disease Due to Diabetic Nephropathy
Yamakado S, Cho H, Inada M, Morikawa M, Jiang YH, Saito K, Nakaishi K, Watabe S, Takagi H, Kaneda M, Nakatsuma A, Ninomiya M, Imachi H, Arai T, Yoshimoto T, Murao K, Chang JH, Chen SM, Shih YC, Zeng MJ , 柯良胤, Chen CH, Yoshimura T, Miura T, Ito E* - - 1 - BMJ Open Diabetes Research & Care - BMJ OPEN DIABETES RESEARCH & CARE 2019 7卷(1期):e000661頁
(IF: 3.183, 領域排名: 74, 領域期刊數: 143, 領域排名: 51.75%)

Urinary Adiponectin as A New Diagnostic Index for Chronic Kidney Disease Due to Diabetic Nephropathy
Yamakado S, Cho H, Inada M, Morikawa M, Jiang YH, Saito K, Nakaishi K, Watabe S, Takagi H, Kaneda M, Nakatsuma A, Ninomiya M, Imachi H, Arai T, Yoshimoto T, Murao K, Chang JH, Chen SM, Shih YC, Zeng MJ , Ke LY, Chen CH, Yoshimura T, Miura T, Ito E* - - 1 - BMJ Open Diabetes Research & Care - BMJ OPEN DIABETES RESEARCH & CARE 2019;7(1):e000661
(IF: 3.183, Journal Ranking: 74, Number of Journals of this Field: 143, Ranking: 51.75%)

28

極低密度脂蛋白調節鈣離子感測蛋白STIM1抑制SOCE造成心房心肌肌蛋白失序
蕭伊伶, 林忻婷, 柯良胤, 吳炳男, 辛錫璋, 陳珠璜, 蔡維中, 朱志生, 李香君* - - 1 - Journal of Clinical Medicine - JOURNAL OF CLINICAL MEDICINE 2019 8卷(6期):881頁
(IF: 5.688, 領域排名: 15, 領域期刊數: 160, 領域排名: 9.38%)

Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes
Shiou YL, Lin HT, Ke LY, Wu BN, Shin SJ, Chen CH, Tsai WC, Chu CS, Lee HC* - - 1 - Journal of Clinical Medicine - JOURNAL OF CLINICAL MEDICINE 2019;8(6):881
(IF: 5.688, Journal Ranking: 15, Number of Journals of this Field: 160, Ranking: 9.38%)

29

Ultrasensitive ELISA developed for diagnosis
Iha K, Inada M, Kawada N, Nakaishi K, Watabe S, Tan YH, Shen C, 柯良胤, Yoshimura T, Ito E* - - 1 - Diagnostics - DIAGNOSTICS 2019 9卷(3期):78頁
(IF: 3.11, 領域排名: 39, 領域期刊數: 165, 領域排名: 23.64%)

Ultrasensitive ELISA developed for diagnosis
Iha K, Inada M, Kawada N, Nakaishi K, Watabe S, Tan YH, Shen C, Ke LY, Yoshimura T, Ito E* - - 1 - Diagnostics - DIAGNOSTICS 2019;9(3):78
(IF: 3.11, Journal Ranking: 39, Number of Journals of this Field: 165, Ranking: 23.64%)

30

Immunoregulatory effects of very low density lipoprotein from healthy individuals and metabolic syndrome patients on glial cells
李佳玲, 朱俊憲, 李香君, 周美鵑, 劉景寬, 陳珠璜, 柯良胤, 陳秀蘭* - - 1 - Immunobiology - IMMUNOBIOLOGY 2019 224卷(5期):632-637頁
(IF: 2.788, 領域排名: 102, 領域期刊數: 158, 領域排名: 64.56%)

Immunoregulatory effects of very low density lipoprotein from healthy individuals and metabolic syndrome patients on glial cells
Chia-Ling Li, Chun-Hsien Chu, Hsiang-Chun Lee, Mei-Chuan Chou, Ching-Kuan Liu, Chu-Huang Chen, Liang-Yin Ke, Shiou-Lan Chen* - - 1 - Immunobiology - IMMUNOBIOLOGY 2019;224(5):632-637
(IF: 2.788, Journal Ranking: 102, Number of Journals of this Field: 158, Ranking: 64.56%)

31

Role of Ceramidases in Sphingolipid Metabolism and Human Diseases
Parveen F†, Bender D†, 劉思慧, Mishra VK, 陳志杰, 柯良胤* - - 1 - Cells - CELLS 2019 8卷(12期):1573頁
(IF: 4.366, 領域排名: 70, 領域期刊數: 195, 領域排名: 35.90%)

Role of Ceramidases in Sphingolipid Metabolism and Human Diseases
Parveen F†, Bender D†, Law SH, Mishra VK, Chen CC, Ke LY* - - 1 - Cells - CELLS 2019;8(12):1573
(IF: 4.366, Journal Ranking: 70, Number of Journals of this Field: 195, Ranking: 35.90%)

32

比較糙米萃取物PGBR與r-oryzanold抗氧化與抗發炎的特性對預防代謝症候群的助益
Hui‐Li Lin, Shih‐Hsiung Lin, Kuo‐Ping Shen, 詹華蓁, Yu‐Hsiu Tseng, Hsueh‐Wei Yen, 劉思慧, 柯良胤* - - 1 - JOURNAL OF FOOD BIOCHEMISTRY - JOURNAL OF FOOD BIOCHEMISTRY 2019 44卷(2期):e13129頁
(IF: 1.662, 領域排名: 85, 領域期刊數: 139, 領域排名: 61.15%)

Efficiency comparison of PGBR extract and γ-oryzanol in antioxidative stress and anti-inflammatory properties against metabolic syndrome
Hui‐Li Lin, Shih‐Hsiung Lin, Kuo‐Ping Shen, Hua‐Chen Chan, Yu‐Hsiu Tseng, Hsueh‐Wei Yen, Shi‐Hui Law, Liang‐Yin Ke* - - 1 - JOURNAL OF FOOD BIOCHEMISTRY - JOURNAL OF FOOD BIOCHEMISTRY 2019;44(2):e13129
(IF: 1.662, Journal Ranking: 85, Number of Journals of this Field: 139, Ranking: 61.15%)

33

黃嘌呤衍生KMUP-1反轉高糖毒性活化之Kv通道經由cAMP/PKA訊息路徑於大鼠胰島乙型細胞
李建興, 朱志生, Tsai HJ, 柯良胤, 李香君, 葉竹來, 陳珠璜, 吳炳男* - - 1 - Chemico-Biological Interactions - CHEMICO-BIOLOGICAL INTERACTIONS 2018 279卷(1期):171-176頁
(IF: 3.296, 領域排名: 75, 領域期刊數: 261, 領域排名: 28.74%)

Xanthine-derived KMUP-1 reverses glucotoxicity-activated Kv channels through the cAMP/PKA signaling pathway in rat pancreatic β cells
Lee CH, Chu CS, Tsai HJ, Ke LY, Lee HC, Yeh JL, Chen CH, Wu BN* - - 1 - Chemico-Biological Interactions - CHEMICO-BIOLOGICAL INTERACTIONS 2018;279(1):171-176
(IF: 3.296, Journal Ranking: 75, Number of Journals of this Field: 261, Ranking: 28.74%)

34

Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo.
Wang YC, Lee AS(共同第一), Lu LS, 柯良胤, Chen WY, Dong JW, Lu J, Chen Z, 朱志生, 詹華蓁, Kuzan TY, Tsai MH, Hsu WL, Dixon RAF, Sawamura T, Chang KC*, 陳珠璜*. - - 1 - Aging Cell - AGING CELL 2018 17卷(14期):e12792頁
(IF: 7.627, 領域排名: 30, 領域期刊數: 189, 領域排名: 15.87%)

Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo.
Wang YC, Lee AS, Lu LS, Ke LY, Chen WY, Dong JW, Lu J, Chen Z, Chu CS, Chan HC, Kuzan TY, Tsai MH, Hsu WL, Dixon RAF, Sawamura T, Chang KC, Chen CH. - - 1 - Aging Cell - AGING CELL 2018;17(14):e12792
(IF: 7.627, Journal Ranking: 30, Number of Journals of this Field: 189, Ranking: 15.87%)

35

Range of L5 LDL levels in healthy adults and L5’s predictive power in patients with hyperlipidemia or coronary artery disease
朱志生†, 詹華蓁†, 蔡明憲, Stancel N, 李香君, 鄭凱鴻, 董宜青, 詹秀娟, 王重雅, 辛錫璋, 賴文德, 楊朝諭, Dixon RA, 陳珠璜*, 柯良胤*. - - 1 - Scientific Reports - SCIENTIFIC REPORTS 2018 8卷(11866期):Aug 8;8(1):11866頁
(IF: 4.122, 領域排名: 12, 領域期刊數: 64, 領域排名: 18.75%)

Range of L5 LDL levels in healthy adults and L5’s predictive power in patients with hyperlipidemia or coronary artery disease
Chu CS†, Chan HC†, Tsai MH, Stancel N, Lee HC, Cheng KH, Tung YC, Chan HCB, Wang CY, Shin SJ, Lai WT, Yang CY, Dixon RA, Chen CH*, Ke LY*. - - 1 - Scientific Reports - SCIENTIFIC REPORTS 2018;8(11866):Aug 8;8(1):11866
(IF: 4.122, Journal Ranking: 12, Number of Journals of this Field: 64, Ranking: 18.75%)

36

以即時定量聚合酶連鎖反應快速篩檢偵測缺失型乙型地中海型貧血
柯良胤, 張建國, 張肇松, 謝麗鈴, 劉大智* - - 1 - JOURNAL OF CLINICAL LABORATORY ANALYSIS - J CLIN LAB ANAL 2017 Jan;31卷(1期):e22019頁
(IF: 1.521, 領域排名: 22, 領域期刊數: 30, 領域排名: 73.33%)

Rapid screening for deleted form β-thalassemia by real-time quantitative PCR
Ke, Liang-Yin; Chang, Jan Gowth; Chang, Chao-Sung; Shieh, Li-Ling; Liu, Ta-Chih - - 1 - JOURNAL OF CLINICAL LABORATORY ANALYSIS - J CLIN LAB ANAL 2017;Jan;31(1):e22019
(IF: 1.521, Journal Ranking: 22, Number of Journals of this Field: 30, Ranking: 73.33%)

37

The role of electronegative low-density lipoprotein in cardiovascular diseases and its therapeutic implications
Sumeyya Akyol, Jonathan Lu, Omer Akyol, Fatih Akcay, Ferah Armutcu, 柯良胤*, 陳珠璜 - - 1 - Trends in Cardiovascular Medicine - Trends Cardiovasc. Med. 2017 27卷(4期):239-246頁
(IF: 4.964, 領域排名: 25, 領域期刊數: 126, 領域排名: 19.84%)

The role of electronegative low-density lipoprotein in cardiovascular diseases and its therapeutic implications
Sumeyya Akyol, Jonathan Lu, Omer Akyol, Fatih Akcay, Ferah Armutcu, Liang-Yin Ke*, and Chu-Huang Chen - - 1 - Trends in Cardiovascular Medicine - Trends Cardiovasc. Med. 2017;27(4):239-246
(IF: 4.964, Journal Ranking: 25, Number of Journals of this Field: 126, Ranking: 19.84%)

38

陰電性低密度脂蛋白誘發代謝症候群脂肪組織發炎反應
柯良胤,詹華蓁,詹秀娟,Kalu FCU,李香君,林怡伶,卓士傑,賴文德,曹承榮, Sawamura T, Dixon RA,陳珠璜,朱志生*,辛錫璋* - - 1 - Journal of Clinical Endocrinology & Metabolism - J CLIN ENDOCR METAB 2017 102卷(12期):4615-4625頁
(IF: 5.455, 領域排名: 20, 領域期刊數: 138, 領域排名: 14.49%)

Electronegative Low-density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated with Metabolic Syndrome
Ke LY, Chan HC, Chan HC, Kalu FCU, Lee HC, Lin IL, Jhuo SJ, Lai WT, Tsao CR, Sawamura T, Dixon RA, Chen CH, Chu CS*, Shin SJ* - - 1 - Journal of Clinical Endocrinology & Metabolism - J CLIN ENDOCR METAB 2017;102(12):4615-4625
(IF: 5.455, Journal Ranking: 20, Number of Journals of this Field: 138, Ranking: 14.49%)

39

Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein
柯良胤, 詹華蓁(共同第一), 陳志杰, Lu J, Marathe GK, 朱志生, 詹秀娟, 王重雅, 董宜青, McIntyre TM, 顏正賢*, 陳珠璜* - - 1 - JOURNAL OF MEDICINAL CHEMISTRY - J MED CHEM 2016 59卷(3期):1032-1040頁
(IF: 5.589, 領域排名: 3, 領域期刊數: 59, 領域排名: 5.08%)

Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein
Ke LY, Chan HC, Chen CC, Lu J, Marathe GK, Chu CS, Chan HBC, Wang CY, Tung YC, McIntyre TM, Yen JH*, Chen CH*. - - 1 - JOURNAL OF MEDICINAL CHEMISTRY - J MED CHEM 2016;59(3):1032-1040
(IF: 5.589, Journal Ranking: 3, Number of Journals of this Field: 59, Ranking: 5.08%)

40

CRP、Atherogenic LDL及LOX-1交互作用及在動脈粥狀硬化致病機轉所扮演的角色
Nicole Stancel, 陳志杰, 柯良胤, 朱志生, Jonathan Lu, Tatsuya Sawamura*, 陳珠璜* - - 1 - CLINICAL CHEMISTRY - CLIN CHEM 2016 62卷(2期):320-327頁
(IF: 7.457, 領域排名: 1, 領域期刊數: 30, 領域排名: 3.33%)

Interplay between CRP, Atherogenic LDL, and LOX-1 and Its Potential Role in the Pathogenesis of Atherosclerosis
Nicole Stancel, Chih-Chieh Chen, Liang-Yin Ke, Chih-Sheng Chu, Jonathan Lu, Tatsuya Sawamura, and Chu-Huang Chen* - - 1 - CLINICAL CHEMISTRY - CLIN CHEM 2016;62(2):320-327
(IF: 7.457, Journal Ranking: 1, Number of Journals of this Field: 30, Ranking: 3.33%)

41

Electronegative Low-Density Lipoprotein Induces Renal Apoptosis and Fibrosis: STRA6 Signaling Involved
陳肇閎, 柯良胤, 詹華蓁, 李安生, 林昆德, 朱志生, 李美月, 蕭璧容, 許勤, 陳珠璜*, 辛錫璋* - - 1 - JOURNAL OF LIPID RESEARCH - J LIPID RES 2016 57卷(8期):1435-1446頁
(IF: 4.368, 領域排名: 67, 領域期刊數: 289, 領域排名: 23.18%)

Electronegative Low-Density Lipoprotein Induces Renal Apoptosis and Fibrosis: STRA6 Signaling Involved
Chen CH, Ke LY, Chan HC, Lee AS, Lin KD, Chu CS, Lee MY, Hsiao PJ, Hsu C, Chen CH*, Shin S*J - - 1 - JOURNAL OF LIPID RESEARCH - J LIPID RES 2016;57(8):1435-1446
(IF: 4.368, Journal Ranking: 67, Number of Journals of this Field: 289, Ranking: 23.18%)

42

代謝症候群中的非常低密度脂蛋白造成心房脂質沉積與心房顫動 的發生有關
李香君, 林忻婷, 柯良胤, 魏綺, 蕭伊伶, 朱志生, 賴文德,辛錫璋, 陳 珠璜, 許勝雄*, 吳炳男* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INT J MOL SCI 2016 17卷(1期):E134頁
(IF: 3.257, 領域排名: 52, 領域期刊數: 163, 領域排名: 31.90%)

VLDL from metabolic syndrome individuals enhanced lipid accumulation in atria with association of susceptibility to atrial fibrillation
Lee HC, Lin HT, Ke LY, Wei C, Hsiao YL, Chu CS, Lai WT, Shin SJ, Chen CH, Sheu SH*, Wu BN*. - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INT J MOL SCI 2016;17(1):E134
(IF: 3.257, Journal Ranking: 52, Number of Journals of this Field: 163, Ranking: 31.90%)

43

美國2013年新版膽固醇治療指引中的四大他汀類降膽固醇藥物受惠者血漿中有較高濃度的陰電性低密度脂蛋白膽固醇
朱志生, 柯良胤, 詹華蓁, 詹秀娟, 陳志杰, 鄭凱鴻, 李香君, 郭炫孚, 張景棠, 張坤正, 許勝雄, 陳珠璜, 賴文德* - - 1 - Acta Cardiologica Sinica - ACTA CARDIOL SIN 2016 32卷(6期):667-675頁
(IF: 0.201, 領域排名: 123, 領域期刊數: 124, 領域排名: 99.19%)

Four Statin Benefit Groups Defined by The 2013 ACC/AHA New Cholesterol Guideline are Characterized by Increased Plasma Level of Electronegative LDL
Chu CS, Ke LY, Chan HC, Chan HCB, Chen CC, Cheng KH, Lee HC, Kuo HF, Chang CT, Chang KC, Sheu SH, Chen CH, Lai WT*. - - 1 - Acta Cardiologica Sinica - ACTA CARDIOL SIN 2016;32(6):667-675
(IF: 0.201, Journal Ranking: 123, Number of Journals of this Field: 124, Ranking: 99.19%)

44

愛滋病定量COBAS AmpliPrep/COBAS TaqMan第一代與第二代試劑比較
董宜青,柯良胤,盧柏樑,林貴香,Su-Chen Lee, Yi-Ying Lin, Li-Chiu Chou,蔡文展* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG J MED SCI 2015 31卷(4期):188-193頁
(IF: 0.803, 領域排名: 107, 領域期刊數: 123, 領域排名: 86.99%)

Comparison of the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 test v1.0 with v2.0 in HIV-1 viral load quantification
Yi-Ching Tung, Liang-Yin Ke, Po-Liang Luc, Kuei-Hsiang Lin, Su-Chen Lee, Yi-Ying Lin, Li-Chiu Chou, Wen-Chan Tsai* - - 1 - KAOHSIUNG JOURNAL OF MEDICAL SCIENCES - KAOHSIUNG J MED SCI 2015;31(4):188-193
(IF: 0.803, Journal Ranking: 107, Number of Journals of this Field: 123, Ranking: 86.99%)

45

從化學本質探討陰電性低密度脂蛋白之致動脈粥狀硬化特性
柯良胤, Nicole Stance(共同第一),Henry Bair, 陳珠璜* - - 1 - Current Atherosclerosis Reports - CURR ATHEROSCLER REP 2014 16卷(8期):428(1-11)頁
(IF: 3.059, 領域排名: 22, 領域期刊數: 65, 領域排名: 33.85%)

The Underlying Chemistry of Electronegative LDL’s Atherogenicity
Liang-Yin Ke, Nicole Stancel, Henry Bair, Chu-Huang Chen* - - 1 - Current Atherosclerosis Reports - CURR ATHEROSCLER REP 2014;16(8):428(1-11)
(IF: 3.059, Journal Ranking: 22, Number of Journals of this Field: 65, Ranking: 33.85%)

46

The development of a beacon-based real-time PCR for cytomegalovirus and its application in immunocompromised patients.
董宜青,柯良胤,蔡文展,林貴香, Tsai SM, Wang CF, Lee HF, Su HJ,盧柏樑* - - 1 - Clinical Laboratory - CLIN LAB 2014 60卷(11期):1895-901頁
(IF: 1.084, 領域排名: 23, 領域期刊數: 31, 領域排名: 74.19%)

The development of a beacon-based real-time PCR for cytomegalovirus and its application in immunocompromised patients.
Tung, Yi-Ching; Ke, Liang-Yin; Tsai, Wen-Chan; Lin, Kuei-Hsiang; Tsai, Shih-Meng; Wang, Chu-Feng; Lee, Hsiao-Fen; Su, Hut-Ju;Lu PL. - - 1 - Clinical Laboratory - CLIN LAB 2014;60(11):1895-901
(IF: 1.084, Journal Ranking: 23, Number of Journals of this Field: 31, Ranking: 74.19%)

 Project

 

 Patent