MENU

 Education

School — Major — Degree Duration

國立成功大學 — 基礎醫學研究所(畢) — 博士

Doctorate, Institute of Basic Medical Sciences, National Cheng Kung University

2001/09 — 2007/06

國立成功大學 — 生理學研究所(畢) — 碩士

Master, Department of Physiology, National Cheng Kung University

1998/09 — 2001/06

高雄醫學院 — 生物學系(畢) — 學士

Bachelor, Department of Biomedical Science and Environment Biology, Kaohsiung Medical University

1994/09 — 1998/06

 Intramural Experience

Office/Department/Institute Position Duration
生理學科 Department of Physiology   Director 2024/08/01 — 2027/07/31
生理學科 Department of Physiology   Professor 2021/08/01 —  
生理學科 Department of Physiology   Associate Professor 2017/08/01 — 2021/07/31
生理學科 Department of Physiology   Assistant Professor 2013/08/01 — 2017/07/31

 Extramural Experience

DEPNO Position- Office/Department/Institute Duration
國立成功大學生物化學科暨生物化學暨分子生物學研究所 助理教授 0990201 — 1020731

 Discipline

NO Discipline Expertise
1 生物醫農類 Biology, Medicine and Agriculture 生物學之生化及分子生物 Biochemistry and Molecular Biology
2 生物醫農類 Biology, Medicine and Agriculture 生理 Physiology

 Research & Technology Platform Open to the Outside

Mouse model of skin wound healing and bone repair

 Interested Area(s)for Interdisciplinary Research

皮膚學; 組織再生與修復

Dermatology; Tissue regeneration and repair

 Area(s) of Expertise & Research

傷口癒合, 膜蛋白酶功能生理學, 細胞生物學, 分子生物學, 發育生物學

Physiology, Cell Biology, Molecular Biology, Developmental Biology

 Publication

NO Publication
1

TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts.
Yi-Kai Hong, Yu-Chen Lin, 鄭琮霖, Chao-Han Lai, Yi-Han Chang, Yu-Lun Huang, Chia-Yi Hung, Chen-Han Wu, Kuo-Shu Hung, Ya-Chu Ku, Yen-Ting Ho, Ming-Jer Tang, Shu-Wha Lin, Guey-Yueh Shi, John A McGrath, Hua-Lin Wu, Chao-Kai Hsu - - 1 - JOURNAL OF BIOMEDICAL SCIENCE - JOURNAL OF BIOMEDICAL SCIENCE 2024 31卷(1期):12頁
(IF: 11, 領域排名: 13, 領域期刊數: 136, 領域排名: 9.56%)

TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts.
Yi-Kai Hong, Yu-Chen Lin, Tsung-Lin Cheng, Chao-Han Lai, Yi-Han Chang, Yu-Lun Huang, Chia-Yi Hung, Chen-Han Wu, Kuo-Shu Hung, Ya-Chu Ku, Yen-Ting Ho, Ming-Jer Tang, Shu-Wha Lin, Guey-Yueh Shi, John A McGrath, Hua-Lin Wu, Chao-Kai Hsu - - 1 - JOURNAL OF BIOMEDICAL SCIENCE - JOURNAL OF BIOMEDICAL SCIENCE 2024;31(1):12
(IF: 11, Journal Ranking: 13, Number of Journals of this Field: 136, Ranking: 9.56%)

2

腫瘤內皮標記 1 調節基質重載可預防腹主動脈瘤
Yi-Kai Hong, 鄭琮霖, Chao-Kai Hsu, Fang-Tzu Lee, Bi-Ing Chang, Kuan-Chieh Wang, Lan-Yun Chang, Hua-Lin Wu*, Chao-Han Lai* - - 1 - International Journal of Biological Sciences - INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 2024 20卷(10期):3691-3709頁
(IF: 8.2, 領域排名: 31, 領域期刊數: 313, 領域排名: 9.90%)

Regulation of matrix reloading by tumor endothelial marker 1 protects against abdominal aortic aneurysm
Yi-Kai Hong, Tsung-Lin Cheng, Chao-Kai Hsu, Fang-Tzu Lee, Bi-Ing Chang, Kuan-Chieh Wang, Lan-Yun Chang, Hua-Lin Wu*, Chao-Han Lai* - - 1 - International Journal of Biological Sciences - INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 2024;20(10):3691-3709
(IF: 8.2, Journal Ranking: 31, Number of Journals of this Field: 313, Ranking: 9.90%)

3

軟骨細胞之凝血酶調節素可對抗骨關節炎
Lin Kang, Ai-Lun Yang#, Chao-Han Lai, 陳贊如, 林松彥, 王彥雄, 王昭仁, Edward M Conway, Hua-Lin Wu, 何美泠, 張瑞根, 陳崇桓*, 鄭琮霖* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 24卷(11期):9522頁
(IF: 5.6, 領域排名: 66, 領域期刊數: 285, 領域排名: 23.16%)

Chondrocyte Thrombomodulin Protects against Osteoarthritis.
Lin Kang, Ai-Lun Yang#, Chao-Han Lai, Tsan-Ju Chen, Sung-Yen Lin, Yan-Hsiung Wang, Chau-Zen Wang, Edward M Conway, Hua-Lin Wu, Mei-Ling Ho, Je-Ken Chang, Chung-Hwan Chen*, Tsung-Lin Cheng* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023;24(11):9522
(IF: 5.6, Journal Ranking: 66, Number of Journals of this Field: 285, Ranking: 23.16%)

4

組蛋白去乙醯化酶抑制劑可減弱 27-羥基膽固醇對大鼠大腦的影響
陳贊如, 洪惠珊, 鄭琮霖, 王錠釧* - - 1 - NEUROSCIENCE LETTERS - NEUROSCIENCE LETTERS 2023 818卷(1期):137533頁
(IF: 2.5, 領域排名: 198, 領域期刊數: 272, 領域排名: 72.79%)

Histone deacetylase inhibitor attenuates the effects of 27-hydroxycholesterol on the rat brain.
Tsan-Ju Chen, Hui-Shan Hung, Tsung-Lin Cheng, Dean-Chuan Wang - - 1 - NEUROSCIENCE LETTERS - NEUROSCIENCE LETTERS 2023;818(1):137533
(IF: 2.5, Journal Ranking: 198, Number of Journals of this Field: 272, Ranking: 72.79%)

5

Tumor endothelial marker 1 is upregulated in heart after cardiac injury and participates in cardiac remodeling.
Po-Sheng Chen, 馮文翰#, Tzu-Hsien Tsai#, Yi-Kai Hong, An-Sheng Lee, Kuan-Cheng Chang, Hsing-Chun Chung, Yen-Wen Liu, Chih-Cheng Hsieh, Yi-Hsian Fang, Pei-Jung Yang, Chawn-Yau Luo, Ping-Yen Liu*, Tsung-Lin Cheng*, Yi-Heng Li* - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2022 12卷(1期):10532頁
(IF: 4.996, 領域排名: 19, 領域期刊數: 73, 領域排名: 26.03%)

Tumor endothelial marker 1 is upregulated in heart after cardiac injury and participates in cardiac remodeling.
Po-Sheng Chen, Wen-Han Feng, Tzu-Hsien Tsai, Yi-Kai Hong, An-Sheng Lee, Kuan-Cheng Chang, Hsing-Chun Chung, Yen-Wen Liu, Chih-Cheng Hsieh, Yi-Hsian Fang, Pei-Jung Yang, Chawn-Yau Luo, Ping-Yen Liu, Tsung-Lin Cheng, Yi-Heng Li - - 1 - SCIENTIFIC REPORTS - SCIENTIFIC REPORTS 2022;12(1):10532
(IF: 4.996, Journal Ranking: 19, Number of Journals of this Field: 73, Ranking: 26.03%)

6

線粒體代謝、AMPK-SIRT 介導的通路、LncRNA 和 MicroRNA 在骨關節炎中的作用
劉皓宇, 張綺芬, 盧政昌, 吳順成, 黃斌, 鄭琮霖, 林松彥, 何承融, 李孟娟, 楊忠達, 王應鈞, 李忠佑, 劉秉政, 魏春旺*, 康琳*, 陳崇桓* - - 1 - Biomedicines - BIOMEDICINES 2022 10卷(7期):1477頁
(IF: 4.757, 領域排名: 86, 領域期刊數: 279, 領域排名: 30.82%)

The Role of Mitochondrial Metabolism, AMPK-SIRT Mediated Pathway, LncRNA and MicroRNA in Osteoarthritis
Liu, Hao-Yu, Chi-Fen Chang, Cheng-Chang Lu, Shun-Cheng Wu, Bin Huang, Tsung-Lin Cheng, Sung-Yen Lin, Cheng-Jung Ho, Mon-Juan Lee, Chung-Da Yang, Ying-Chun Wang, Jhong-You Li, Ping-Cheng Liu, Chun-Wang Wei*, Lin Kang*, & Chung-Hwan Chen* - - 1 - Biomedicines - BIOMEDICINES 2022;10(7):1477
(IF: 4.757, Journal Ranking: 86, Number of Journals of this Field: 279, Ranking: 30.82%)

7

Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis
周心喬 ,林松彥#, 周亮吟, 何美泠, 莊淑君, 鄭琮霖, 康琳, 林怡珊, 王彥雄, 魏春旺, 陳崇桓*, 王昭仁* - - 1 - BIOMEDICINES - BIOMEDICINES 2022 10卷(9期):2173頁
(IF: 4.757, 領域排名: 121, 領域期刊數: 297, 領域排名: 40.74%)

Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis
Hsin-Chiao Chou, Sung-Yen Lin†, Liang-Yin Chou, Mei-Ling Ho, Shu-Chun Chuang, Tsung-Lin Cheng, Lin Kang, Yi-Shan Lin, Yan-Hsiung Wang, Chun-Wang Wei, Chung-Hwan Chen* and Chau-Zen Wang* - - 1 - BIOMEDICINES - BIOMEDICINES 2022;10(9):2173
(IF: 4.757, Journal Ranking: 121, Number of Journals of this Field: 297, Ranking: 40.74%)

8

Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis
黃炫迪,鄭琮霖,Chung-Da Yang,Chi-Fen Chang,何承融,莊淑君,李忠佑,黃士豪,林怡珊,沈欣毅,余宗翰,康琳*,林松彥*,陳崇桓* - - 1 - Antioxidants - ANTIOXIDANTS 2021 26卷(10(2)期):178頁
(IF: 6.313, 領域排名: 6, 領域期刊數: 62, 領域排名: 9.68%)

Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis
Hsuan-Ti Huang, Tsung-Lin Cheng, Chung-Da Yang, Chi-Fen Chang, Cheng-Jung Ho, Shu-Chun Chuang, Jhong-You Li, Shih-Hao Huang, Yi-Shan Lin, Hsin-Yi Shen, Tsung-Han Yu, Lin Kang, Sung-Yen Lin, Chung-Hwan Chen - - 1 - Antioxidants - ANTIOXIDANTS 2021;26(10(2)):178
(IF: 6.313, Journal Ranking: 6, Number of Journals of this Field: 62, Ranking: 9.68%)

9

An Intermediate Concentration of Calcium with Antioxidant Supplement in Culture Medium Enhances Proliferation and Decreases the Aging of Bone Marrow Mesenchymal Stem Cells
楊忠達,莊淑君#,鄭琮霖,李孟娟,陳惠亭,林松彥,黃炫迪,何承融,林怡珊,康琳,何美泠*,張瑞根*,陳崇桓* - - 1 - Int J Mol Sci - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021 20卷(22(4)期):2095頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

An Intermediate Concentration of Calcium with Antioxidant Supplement in Culture Medium Enhances Proliferation and Decreases the Aging of Bone Marrow Mesenchymal Stem Cells
Chung-Da Yang, Shu-Chun Chuang, Tsung-Lin Cheng, Mon-Juan Lee, Hui-Ting Chen, Sung-Yen Lin, Hsuan-Ti Huang, Cheng-Jung Ho, Yi-Shan Lin, Lin Kang , Mei-Ling Ho, Je-Ken Chang , Chung-Hwan Chen - - 1 - Int J Mol Sci - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021;20(22(4)):2095
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

10

Recombinant thrombomodulin lectin-like domain attenuates porphyromonas gingivalis lipopolysaccharide-induced osteoclastogenesis and periodontal bone resorption.
張藍云, 賴昭翰, 郭承翔, 張碧英, 吳華林, 鄭琮霖* - - 1 - Journal of periodontology - JOURNAL OF PERIODONTOLOGY 2021 92卷(11期):1622-1634頁
(IF: 4.494, 領域排名: 12, 領域期刊數: 92, 領域排名: 13.04%)

Recombinant thrombomodulin lectin-like domain attenuates porphyromonas gingivalis lipopolysaccharide-induced osteoclastogenesis and periodontal bone resorption.
Lan-Yun Chang, Chao-Han Lai, Cheng-Hsiang Kuo, Bi-Ing Chang, Hua-Lin Wu, Tsung-Lin Cheng* - - 1 - Journal of periodontology - JOURNAL OF PERIODONTOLOGY 2021;92(11):1622-1634
(IF: 4.494, Journal Ranking: 12, Number of Journals of this Field: 92, Ranking: 13.04%)

11

Role of tumor endothelial marker 1 (Endosialin/CD248) lectin-like domain in lipopolysaccharide-induced macrophage activation and sepsis in mice
鄭琮霖, 林雨璇, 洪羿凱, 馬志遠, 蔡弘文, 施桂月, 吳華林*, 賴昭翰* - - 1 - Translational Research - TRANSLATIONAL RESEARCH 2021 232卷(-期):150-162頁
(IF: 10.171, 領域排名: 2, 領域期刊數: 29, 領域排名: 6.90%)

Role of tumor endothelial marker 1 (Endosialin/CD248) lectin-like domain in lipopolysaccharide-induced macrophage activation and sepsis in mice
Tsung-Lin Cheng, Yu-Syuan Lin, Yi-Kai Hong, Chih-Yuan Ma, Hung-Wen Tsai, Guey-Yueh Shi, Hua-Lin Wu*, Chao-Han Lai* - - 1 - Translational Research - TRANSLATIONAL RESEARCH 2021;232(-):150-162
(IF: 10.171, Journal Ranking: 2, Number of Journals of this Field: 29, Ranking: 6.90%)

12

Molecular weight of hyaluronic acid has major influence on its efficacy and safety for viscosupplementation in hip osteoarthritis: a systematic review and meta-analysis.
吳彥榮,黃炫迪#,何承融,石佳隴,陳崇桓,鄭琮霖,王應鈞,林松彥* - - 1 - Cartilage - CARTILAGE 2021 2021卷(10期):19476035211021903頁
(IF: 4.634, 領域排名: 11, 領域期刊數: 82, 領域排名: 13.41%)

Molecular weight of hyaluronic acid has major influence on its efficacy and safety for viscosupplementation in hip osteoarthritis: a systematic review and meta-analysis.
Yen-Zung Wu , Hsuan-Ti Huang#, Cheng-Jung Ho, Chia-Lung Shih, Chung-Hwan Chen, Tsung-Lin Cheng, Ying-Chun Wang, and Sung-Yen Lin - - 1 - Cartilage - CARTILAGE 2021;2021(10):19476035211021903
(IF: 4.634, Journal Ranking: 11, Number of Journals of this Field: 82, Ranking: 13.41%)

13

Raloxifene Ameliorates Glucosamine-Induced Insulin Resistance in Ovariectomized Rats
陳崇桓#, 鄭琮霖#,張綺芬, 黃炫迪, 林松彥,吳孟興,康琳* - - 1 - Biomedicines - BIOMEDICINES 2021 9卷(9期):1114頁
(IF: 6.081, 領域排名: 65, 領域期刊數: 298, 領域排名: 21.81%)

Raloxifene Ameliorates Glucosamine-Induced Insulin Resistance in Ovariectomized Rats
Chung-Hwan Chen,Tsung-Lin Cheng, Chi-Fen Chang, Hsuan-Ti Huang, Sung-Yen Lin, Meng-Hsing Wu, Lin Kang - - 1 - Biomedicines - BIOMEDICINES 2021;9(9):1114
(IF: 6.081, Journal Ranking: 65, Number of Journals of this Field: 298, Ranking: 21.81%)

14

Application of microRNA in Human Osteoporosis and Fragility Fracture: A Systemic Review of Literatures.
吳彥榮,黃炫迪#,鄭琮霖,呂衍謀,林松彥,何承融,李天慶,許家豪,黃鵬如, Han Hsiang Huang,李忠祐,蘇育德,陳建志,康琳*,陳崇桓* - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021 22卷(10期):5232頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Application of microRNA in Human Osteoporosis and Fragility Fracture: A Systemic Review of Literatures.
Yen-Zung Wu, Hsuan-Ti Huang, Tsung-Lin Cheng, Yen-Mou Lu, Sung-Yen Lin, Cheng-Jung Ho, Tien-Ching Lee, Chia-Hao Hsu, Peng-Ju Huang, Han Hsiang Huang, Jhong-You Li, Yu-De Su, Shih-Chieh Chen, Lin Kang, Chung-Hwan Chen - - 1 - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021;22(10):5232
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

15

Upregulation of Fibrinogen-Like 1 Expression Contributes to Reducing the Progression of Preeclampsia.
鄭琮霖, 陳崇桓, 吳孟興, 賴昭翰, 李可弘, 林聖翔, 蕭璦莉, 吳昭良, 康琳* - - 1 - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2021 9卷(-期):757643頁
(IF: 6.081, 領域排名: 6, 領域期刊數: 39, 領域排名: 15.38%)

Upregulation of Fibrinogen-Like 1 Expression Contributes to Reducing the Progression of Preeclampsia.
Tsung-Lin Cheng, Chung-Hwan Chen, Meng-Hsing Wu, Chao-Han Lai, Ko-Hung Lee, Sheng-Hsiang Lin, Ai-Li Shiau, Chao-Liang Wu, Lin Kang* - - 1 - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2021;9(-):757643
(IF: 6.081, Journal Ranking: 6, Number of Journals of this Field: 39, Ranking: 15.38%)

16

Green Tea Catechin (-)-Epigallocatechin-3-Gallate (EGCG) Facilitates Fracture Healing
林松彥,甘蓉瑜,盧政昌,Han Hsiang Huang,鄭琮霖,黃炫迪,何承融,李天慶,莊淑君,林怡珊,Lin Kang*,陳崇桓* - - 1 - Biomolecules - BIOMOLECULES 2020 10卷(4期):620頁
(IF: 4.879, 領域排名: 96, 領域期刊數: 298, 領域排名: 32.21%)

Green Tea Catechin (-)-Epigallocatechin-3-Gallate (EGCG) Facilitates Fracture Healing
Sung-Yen Lin,Jung Yu Kan,Cheng-Chang Lu,Han Hsiang Huang,Tsung-Lin Cheng,Hsuan-Ti Huang,Cheng-Jung Ho,Tien-Ching Lee,Shu-Chun Chuang,Yi-Shan Lin,Lin Kang*,Chung-Hwan Chen* - - 1 - Biomolecules - BIOMOLECULES 2020;10(4):620
(IF: 4.879, Journal Ranking: 96, Number of Journals of this Field: 298, Ranking: 32.21%)

17

脂質和脂蛋白對用於心臟組織再生的間質幹細胞的影響
林逸翔,康琳,馮文翰,鄭崇霖,蔡維中,黃炫迪,李香君*,陳崇桓* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 13卷(21期):4770頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Effects of Lipids and Lipoproteins on Mesenchymal Stem Cells Used in Cardiac Tissue Regeneration
Yi-Hsiung Lin, Lin Kang, Wen-Han Feng, Tsung-Lin Cheng, Wei-Chung Tsai, Hsuan-Ti Huang, Hsiang-Chun Lee, Chung-Hwan Chen* - - 1 - International Journal of Molecular Sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;13(21):4770
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

18

Thrombomodulin Functional Domains Support Osteoblast Differentiation and Bone Healing in Diabetes in Mice
陳崇桓, Chao‐Han Lai, Yi‐Kai Hong, Jui‐Ming Lu, 林松彥, 李天慶, Lan‐Yun Chang, 何美泠, Edward M Conway, Hua‐Lin Wu, 鄭琮霖* - - 1 - Journal of Bone and Mineral Research - JOURNAL OF BONE AND MINERAL RESEARCH 2020 35卷(9期):1812-1823頁
(IF: 6.741, 領域排名: 19, 領域期刊數: 145, 領域排名: 13.10%)

Thrombomodulin Functional Domains Support Osteoblast Differentiation and Bone Healing in Diabetes in Mice
Chung‐Hwan Chen, Chao‐Han Lai, Yi‐Kai Hong, Jui‐Ming Lu, Sung‐Yen Lin, Tien‐Ching Lee, Lan‐Yun Chang, Mei‐Ling Ho, Edward M Conway, Hua‐Lin Wu, Tsung‐Lin Cheng* - - 1 - Journal of Bone and Mineral Research - JOURNAL OF BONE AND MINERAL RESEARCH 2020;35(9):1812-1823
(IF: 6.741, Journal Ranking: 19, Number of Journals of this Field: 145, Ranking: 13.10%)

19

Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
周心喬, 陳崇桓, 周亮吟, 鄭琮霖, 康琳, 莊淑君, 林怡珊, 何美泠, 王彥雄, 林松彥*, 王昭仁* - - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21卷(19期):6991頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
Hsin-Chaio Chou, Chung-Hwan Chen, Liang-Yin Chou, Tsung-Lin Cheng, Lin Kang, Shu-Chun Chuang, Yi-Shan Lin, Mei-Ling Ho, Yan-Hsiung Wang, Sung-Yen Lin*, Chau-Zen Wang* - - 1 - International journal of molecular sciences - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(19):6991
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

20

Discoidin domain receptor 1 regulates Runx2 during osteogenesis of osteoblasts and promotes bone ossification via phosphorylation of p-38.
周亮吟, 陳崇桓, 莊淑君, 鄭琮霖, 林逸翔, 周心喬, 傅尹志, 王彥雄, 王昭仁* - - 1 - International Journal of Molecular Sciences. - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 21卷(19期):7210頁
(IF: 5.923, 領域排名: 67, 領域期刊數: 298, 領域排名: 22.48%)

Discoidin domain receptor 1 regulates Runx2 during osteogenesis of osteoblasts and promotes bone ossification via phosphorylation of p-38.
Liang-Yin Chou, Chung-Hwan Chen, Shu-Chun Chuang, Tsung-Lin Cheng, Yi-Hsiung Lin, Hsin-Chiao Chou, Yin-Chih Fu, Yan-Hsiung Wang, Chau-Zen Wang*. - - 1 - International Journal of Molecular Sciences. - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020;21(19):7210
(IF: 5.923, Journal Ranking: 67, Number of Journals of this Field: 298, Ranking: 22.48%)

21

Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model
黃炫迪,鄭琮霖,何承融,HanHsiangHuang,盧政昌,莊淑君,李忠佑,李天慶,Shih-TseChe,林怡珊,李智堯,康琳*,林松彥*,陳崇桓* - - 1 - Antioxidants - ANTIOXIDANTS 2020 23卷(10(1)期):8頁
(IF: 6.313, 領域排名: 6, 領域期刊數: 62, 領域排名: 9.68%)

Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model
Hsuan-Ti Huang, Tsung-Lin Cheng, Cheng-Jung Ho, Han Hsiang Huang, Cheng-Chang Lu , Shu-Chun Chuang, Jhong-You Li, Tien-Ching Lee, Shih-Tse Chen, Yi-Shan Lin, Chih-Yao Lee, Lin Kang*, Sung-Yen Lin*, Chung-Hwan Chen* - - 1 - Antioxidants - ANTIOXIDANTS 2020;23(10(1)):8
(IF: 6.313, Journal Ranking: 6, Number of Journals of this Field: 62, Ranking: 9.68%)

22

Osteoprotective Roles of Green Tea Catechins
黃炫迪,鄭琮霖,林松彥,何承融,JoannaYChyu,Rong-Senng,陳崇桓*,Chwan-LiShen* - - 2 - Antioxidants (Basel) - ANTIOXIDANTS 2020 6卷((9)11期):1136頁
(IF: 6.312, 領域排名: 11, 領域期刊數: 144, 領域排名: 7.64%)

Osteoprotective Roles of Green Tea Catechins
Hsuan-Ti Huang 1 2 3 4 5, Tsung-Lin Cheng 1 5 6, Sung-Yen Lin 1 2 3 4, Cheng-Jung Ho 1 2 3, Joanna Y Chyu 7, Rong-Sen Yang, Chung-Hwan Chen*, Chwan-Li Shen* - - 2 - Antioxidants (Basel) - ANTIOXIDANTS 2020;6((9)11):1136
(IF: 6.312, Journal Ranking: 11, Number of Journals of this Field: 144, Ranking: 7.64%)

23

Pharmacological Inhibition of Cathepsin S Suppresses Abdominal Aortic Aneurysm in Mice.
賴昭翰, 張俊彥, 王冠傑, 李芳姿, 吳華林, 鄭琮霖* - - 1 - EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY - EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY 2020 59卷(6期):990-999頁
(IF: 7.069, 領域排名: 9, 領域期刊數: 212, 領域排名: 4.25%)

Pharmacological Inhibition of Cathepsin S Suppresses Abdominal Aortic Aneurysm in Mice.
Chao-Han Lai, Jang-Yang Chang, Kuan-Chieh Wang, Fang-Tzu Lee, Hua-Lin Wu, Tsung-Lin Cheng* - - 1 - EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY - EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY 2020;59(6):990-999
(IF: 7.069, Journal Ranking: 9, Number of Journals of this Field: 212, Ranking: 4.25%)

24

(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
林松彥, 康琳, 陳建志, 王昭仁, 黃炫迪, 李孟娟, 鄭琮霖, 張綺芬, 林怡珊, 陳崇桓* - - 1 - Phytomedicine - PHYTOMEDICINE 2019 55卷(-期):165-171頁
(IF: 4.18, 領域排名: 1, 領域期刊數: 27, 領域排名: 3.70%)

(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
Lin SY, Kang L, Chen JC, Wang CZ, Huang HH, Lee MJ, Cheng TL, Chang CF, Lin YS, Chen CH* - - 1 - Phytomedicine - PHYTOMEDICINE 2019;55(-):165-171
(IF: 4.18, Journal Ranking: 1, Number of Journals of this Field: 27, Ranking: 3.70%)

25

Tumor Endothelial Marker 1 (TEM1/endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors.
Hong YK, Lee YC, 鄭琮霖, Lai CH, Hsu CK, Kuo CH, Hsu YY, Li JT, Chang BI, Ma CY, Lin SW, Wang KC, Shi GY, Wu HL - - 1 - Journal of Investigative Dermatology - JOURNAL OF INVESTIGATIVE DERMATOLOGY 2019 ?卷(?期):10.1016/j.jid.2019.03.114頁
(IF: 6.29, 領域排名: 4, 領域期刊數: 66, 領域排名: 6.06%)

Tumor Endothelial Marker 1 (TEM1/endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors.
Hong YK, Lee YC, Cheng TL, Lai CH, Hsu CK, Kuo CH, Hsu YY, Li JT, Chang BI, Ma CY, Lin SW, Wang KC, Shi GY, Wu HL - - 1 - Journal of Investigative Dermatology - JOURNAL OF INVESTIGATIVE DERMATOLOGY 2019;?(?):10.1016/j.jid.2019.03.114
(IF: 6.29, Journal Ranking: 4, Number of Journals of this Field: 66, Ranking: 6.06%)

26

(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
Sung-Yen Lin, Lin Kang, Jian Chih Chen, Chau-Zen Wang, Han Hsiang Huang, Lee Mon-Juan, 鄭琮霖, Chi-Fen Chang, Yi-Shan Lin, 陳崇桓* - - 1 - Phytomedicine - PHYTOMEDICINE 2018 55卷(?期):165-171頁
(IF: 3.61, 領域排名: 28, 領域期刊數: 226, 領域排名: 12.39%)

(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
Sung-Yen Lin, Lin Kang, Jian Chih Chen, Chau-Zen Wang, Han Hsiang Huang, Lee Mon-Juan, Tsung-Lin Cheng, Chi-Fen Chang, Yi-Shan Lin, Chung-Hwan Chen* - - 1 - Phytomedicine - PHYTOMEDICINE 2018;55(?):165-171
(IF: 3.61, Journal Ranking: 28, Number of Journals of this Field: 226, Ranking: 12.39%)

27

Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing
鄭琮霖, Po-Ku Chen, Wei-Kai Huang, Cheng-Hsiang Kuo, Chia-Fong Cho, Kuan-Chieh Wang, Guey-Yueh Shi, Hua-Lin Wu*, Chao-Han Lai* - - 1 - Journal of Molecular Medicine - JOURNAL OF MOLECULAR MEDICINE-JMM 2018 96卷(12期):1333–1344頁
(IF: 4.938, 領域排名: 20, 領域期刊數: 133, 領域排名: 15.04%)

Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing
Tsung-Lin Cheng, Po-Ku Chen, Wei-Kai Huang, Cheng-Hsiang Kuo, Chia-Fong Cho, Kuan-Chieh Wang, Guey-Yueh Shi, Hua-Lin Wu*, Chao-Han Lai* - - 1 - Journal of Molecular Medicine - JOURNAL OF MOLECULAR MEDICINE-JMM 2018;96(12):1333–1344
(IF: 4.938, Journal Ranking: 20, Number of Journals of this Field: 133, Ranking: 15.04%)

28

(−)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
Sung-Yen Lin, Lin Kang, Chau-Zen Wang, Han Hsiang Huang, 鄭琮霖, Hsuan-Ti Huang, Mon-Juan Lee, Yi-Shan Lin, Mei-Ling Ho, Gwo-Jaw Wang and 陳崇桓* - - 1 - Molecules - MOLECULES 2018 ?卷(23期):3221頁
(IF: 3.098, 領域排名: 68, 領域期刊數: 170, 領域排名: 40.00%)

(−)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
Sung-Yen Lin, Lin Kang, Chau-Zen Wang, Han Hsiang Huang, Tsung-Lin Cheng, Hsuan-Ti Huang, Mon-Juan Lee, Yi-Shan Lin, Mei-Ling Ho, Gwo-Jaw Wang and Chung-Hwan Chen* - - 1 - Molecules - MOLECULES 2018;?(23):3221
(IF: 3.098, Journal Ranking: 68, Number of Journals of this Field: 170, Ranking: 40.00%)

29

Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon.
陳嘉炘,林怡伶,陳崇桓,王彥雄,葉明龍,鄭琮霖,王昭仁* - - 1 - PLoS One - PLOS ONE 2018 13卷(10期):e0205258.頁
(IF: 2.766, 領域排名: 15, 領域期刊數: 64, 領域排名: 23.44%)

Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon.
Chen CH, Lin YH, Chen CH, Wang YH, Yeh ML, Cheng TL, Wang CZ*. - - 1 - PLoS One - PLOS ONE 2018;13(10):e0205258.
(IF: 2.766, Journal Ranking: 15, Number of Journals of this Field: 64, Ranking: 23.44%)

30

(-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
林松彥,康琳,王昭仁,黃漢翔,鄭琮霖, 黃炫迪,李孟娟,林怡珊,何美泠,王國照, 陳崇桓 * - - 1 - Molecules - MOLECULES 2018 23,卷(1期):3221頁
(IF: 3.098, 領域排名: 68, 領域期刊數: 170, 領域排名: 40.00%)

(-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Lin SY, Kang L, Wang CZ, Huang HH, Cheng TL, Huang HT, Lee MJ, Lin YS, Ho ML, Wang GJ, Chen CH * - - 1 - Molecules - MOLECULES 2018;23,(1):3221
(IF: 3.098, Journal Ranking: 68, Number of Journals of this Field: 170, Ranking: 40.00%)

31

Exercise training ameliorates glucosamine-induced insulin resistance in ovariectomized rats.
陳崇桓, Huang TH, 鄭琮霖, Chang CF, 王昭仁, Wu MH, 康琳* - - 1 - MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY - MENOPAUSE 2017 24卷(6期):617-623頁
(IF: 2.733, 領域排名: 21, 領域期刊數: 80, 領域排名: 26.25%)

Exercise training ameliorates glucosamine-induced insulin resistance in ovariectomized rats.
Chen CH, Huang TH, Cheng TL, Chang CF, Wang CZ, Wu MH, Kang L* - - 1 - MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY - MENOPAUSE 2017;24(6):617-623
(IF: 2.733, Journal Ranking: 21, Number of Journals of this Field: 80, Ranking: 26.25%)

32

攜帶凝血酶調節素類凝集素功能區的腺相關病毒載體用於治療腹主動脈瘤
Chao-Han Lai, Kuan-Chieh Wang, Cheng-Hsiang Kuo, Fang-Tzu Lee, 鄭琮霖, Bi-Ing Chang, Yu-Jen Yanga, Guey-Yueh Shi*, Hua-Lin Wu* - - 1 - Atherosclerosis - Atherosclerosis 2017 ?卷(?期):?頁
(IF: 3.942, 領域排名: 12, 領域期刊數: 63, 領域排名: 19.05%)

Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm
Chao-Han Lai, Kuan-Chieh Wang, Cheng-Hsiang Kuo, Fang-Tzu Lee, Tsung-Lin Cheng, Bi-Ing Chang, Yu-Jen Yanga, Guey-Yueh Shi*, Hua-Lin Wu* - - 1 - Atherosclerosis - Atherosclerosis 2017;?(?):?
(IF: 3.942, Journal Ranking: 12, Number of Journals of this Field: 63, Ranking: 19.05%)

33

Toll樣受體4對於腹主動脈瘤的發展是必要的
Chao-Han Lai, Kuan-Chieh Wang, Fang-Tzu Lee, Hung-Wen Tsai, Chih-Yuan Ma, 鄭琮霖, Bi-Ing Chang, Yu-Jen Yang, Guey-Yueh Shi , Hua-Lin Wu - - 1 - PLOS ONE - PLOS ONE 2016 11卷(1期):e0146565頁
(IF: 3.234, 領域排名: 9, 領域期刊數: 57, 領域排名: 15.79%)

Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm
Chao-Han Lai, Kuan-Chieh Wang, Fang-Tzu Lee, Hung-Wen Tsai, Chih-Yuan Ma, Tsung-Lin Cheng, Bi-Ing Chang, Yu-Jen Yang, Guey-Yueh Shi , Hua-Lin Wu - - 1 - PLOS ONE - PLOS ONE 2016;11(1):e0146565
(IF: 3.234, Journal Ranking: 9, Number of Journals of this Field: 57, Ranking: 15.79%)

34

髓系凝血酶調節素類凝集素功能區抑制食骨細胞生成作用與發炎性骨質流失
鄭琮霖, 賴昭翰, 謝式洲, 周吟柏, 葉竹來, 楊艾倫, 王彥雄, 王昭仁, 陳崇桓, 施桂月, 何美泠*, 吳華林* - - 1 - Scientific Reports - SCI REP-UK 2016 ?6卷(-期):28340頁
(IF: 5.228, 領域排名: 7, 領域期刊數: 63, 領域排名: 11.11%)

Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss
Tsung-Lin Cheng, Chao-Han Lai, Shyh-Jou Shieh, Yin-Bo Jou, Jwu-Lai Yeh, Ai-Lun Yang, Yan-Hsiung Wang, Chau-Zen Wang, Chung-Hwan Chen, Guey-Yueh Shi, Mei-Ling Ho*, Hua-Lin Wu* - - 1 - Scientific Reports - SCI REP-UK 2016;?6(-):28340
(IF: 5.228, Journal Ranking: 7, Number of Journals of this Field: 63, Ranking: 11.11%)

35

急性運動改善去勢高血壓大鼠之乙酰膽鹼誘發血管舒張改善
鄭琮霖, Yi-Yuan Lin, Chia-Ting Su, Chun-Che Hu, 楊艾倫 - - 1 - CHINESE JOURNAL OF PHYSIOLOGY - CHINESE J PHYSIOL 2016 59卷(3期):165-72頁
(IF: 0.962, 領域排名: 74, 領域期刊數: 83, 領域排名: 89.16%)

Improvement of Acetylcholine-Induced Vasodilation by Acute Exercise in Ovariectomized Hypertensive Rats
Tsung-Lin Cheng, Yi-Yuan Lin, Chia-Ting Su, Chun-Che Hu and Ai-Lun Yang - - 1 - CHINESE JOURNAL OF PHYSIOLOGY - CHINESE J PHYSIOL 2016;59(3):165-72
(IF: 0.962, Journal Ranking: 74, Number of Journals of this Field: 83, Ranking: 89.16%)

36

凝血酶調節素透過與纖連蛋白結合而促進局部黏附磷酸激酶的活化並進而提升血管新生
Yun-Yan Hsu, Guey-Yueh Shi, Kuan-Chieh Wang, Chih-Yuan Ma, 鄭琮霖, Hua-Lin Wu - - 1 - Oncotarget - ONCOTARGET 2016 7卷(42期):68122-68139頁
(IF: 5.008, 領域排名: 36, 領域期刊數: 213, 領域排名: 16.90%)

Thrombomodulin promotes focal adhesion kinase activation and contributes to angiogenesis by binding to fibronectin
Yun-Yan Hsu, Guey-Yueh Shi, Kuan-Chieh Wang, Chih-Yuan Ma, Tsung-Lin Cheng, Hua-Lin Wu - - 1 - Oncotarget - ONCOTARGET 2016;7(42):68122-68139
(IF: 5.008, Journal Ranking: 36, Number of Journals of this Field: 213, Ranking: 16.90%)

37

凝血酶調節素藉由調控TLR4表現促進糖尿病傷口癒合
鄭琮霖, 賴昭翰, 陳柏谷, 卓家楓, 許云燕, 王冠傑, 林韋伶, 張碧英, 劉詩凱, 吳雨庭, 許釗凱, 施桂月*, 吳華林* - - 1 - JOURNAL OF INVESTIGATIVE DERMATOLOGY - J INVEST DERMATOL 2015 135卷(6期):1668-75頁
(IF: 6.915, 領域排名: 1, 領域期刊數: 61, 領域排名: 1.64%)

Thrombomodulin promotes diabetic wound healing by regulating toll-like receptor 4 expression
Tsung-Lin Cheng, Chao-Han Lai, Po-Ku Chen, Chia-Fong Cho, Yun-Yan Hsu, Kuan-Chieh Wang, Wei-Ling Lin, Bi-Ing Chang, Shi-Kai Liu, Yu-Ting Wu, Chao-Kai Hsu, Guey-Yueh Shi*, Hua-Lin Wu* - - 1 - JOURNAL OF INVESTIGATIVE DERMATOLOGY - J INVEST DERMATOL 2015;135(6):1668-75
(IF: 6.915, Journal Ranking: 1, Number of Journals of this Field: 61, Ranking: 1.64%)

38

長期跑步訓練可改善由胰島素和胰島素樣生長因子1調節的內皮依賴性血管舒張與高血壓
Lin YY, Lee SD, Su CT, 鄭琮霖, Yang AL* - - 0 - Journal of Applied Physiology - J Appl Physiol 2015 119卷(6期):663-9頁
(IF: 3.004, 領域排名: 12, 領域期刊數: 82, 領域排名: 14.63%)

Long-term treadmill training ameliorates endothelium-dependent vasorelaxation mediated by insulin and insulin-like growth factor-1 in hypertension
Lin YY, Lee SD, Su CT, Cheng TL, Yang AL* - - 0 - Journal of Applied Physiology - J Appl Physiol 2015;119(6):663-9
(IF: 3.004, Journal Ranking: 12, Number of Journals of this Field: 82, Ranking: 14.63%)

39

凝血酶調節素調控腹主動脈瘤內巨噬細胞的發炎反應
Kuan-Chieh Wang, Yi-Heng Li, Guey-Yueh Shi, Hung-Wen Tsai, Chawn-Yau Luo, Min-Hua Cheng, Chih-Yuan Ma, Yun-Yan Hsu, 鄭琮霖, Bi-Ing Chang, Chao-Han Lai, Hua-Lin Wu - - 1 - ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY - ARTERIOSCL THROM VAS 2015 35卷(11期):2412-2422頁
(IF: 6.088, 領域排名: 4, 領域期刊數: 60, 領域排名: 6.67%)

Membrane-Bound Thrombomodulin Regulates Macrophage Inflammation in Abdominal Aortic Aneurysm
Kuan-Chieh Wang, Yi-Heng Li, Guey-Yueh Shi, Hung-Wen Tsai, Chawn-Yau Luo, Min-Hua Cheng, Chih-Yuan Ma, Yun-Yan Hsu, Tsung-Lin Cheng, Bi-Ing Chang, Chao-Han Lai, Hua-Lin Wu - - 1 - ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY - ARTERIOSCL THROM VAS 2015;35(11):2412-2422
(IF: 6.088, Journal Ranking: 4, Number of Journals of this Field: 60, Ranking: 6.67%)

40

β-萘黃酮通過減少TNF-α誘導的內皮細胞活化而改善腹膜炎症狀
Sheng-Yao Hsu, Je-Wen Liou, 鄭琮霖, Shih-Yi Peng, Chi-Chen Lin, Yuan-Yuan Chu, Wei-Cheng Luo, Zheng-Kai Huang, Shinn-Jong Jiang* - - 1 - PHARMACOLOGICAL RESEARCH - PHARMACOL RES 2015 X卷(X期):doi:10.1016/j.phrs.2015.10.001頁
(IF: 4.816, 領域排名: 27, 領域期刊數: 253, 領域排名: 10.67%)

beta-Naphthoflavone protects from peritonitis by reducing TNF-alpha-induced endothelial cell activation.
Sheng-Yao Hsu, Je-Wen Liou, Tsung-Lin Cheng, Shih-Yi Peng, Chi-Chen Lin, Yuan-Yuan Chu, Wei-Cheng Luo, Zheng-Kai Huang, Shinn-Jong Jiang - - 1 - PHARMACOLOGICAL RESEARCH - PHARMACOL RES 2015;X(X):doi:10.1016/j.phrs.2015.10.001
(IF: 4.816, Journal Ranking: 27, Number of Journals of this Field: 253, Ranking: 10.67%)

41

乙酰膽鹼所致的血管舒張改善急性運動去勢高血壓大鼠
鄭琮霖, Yi-Yuan Lin, Chia-Ting Su, Chun-Che Hu, Ai-Lun Yang* - - 1 - Chinese Journal of Physiology - CHINESE J PHYSIOL 2015 ?卷(?期):?頁
(IF: 1.163, 領域排名: 73, 領域期刊數: 83, 領域排名: 87.95%)

Improvement of Acetylcholine-Induced Vasodilation by Acute Exercise in Ovariectomized Hypertensive Rats
Tsung-Lin Cheng, Yi-Yuan Lin, Chia-Ting Su, Chun-Che Hu, Ai-Lun Yang* - - 1 - Chinese Journal of Physiology - CHINESE J PHYSIOL 2015;?(?):?
(IF: 1.163, Journal Ranking: 73, Number of Journals of this Field: 83, Ranking: 87.95%)

42

苯甲酸4‐(3,4,5‐Trimethoxyphenoxy)與其甲基衍生物對兩種乳癌細胞株的行為選擇性凋亡能力
KUAN‐HAN LEE, 何文譽, SHU‐JING WU, 鄭琮霖, PO‐JUI HUANG, CLAY C. C. WANG, JUI‐HSIANG HUNG* - - 1 - ANTICANCER RESEARCH - ANTICANCER RES 2014 34卷(4期):1801-1809頁
(IF: 1.872, 領域排名: 145, 領域期刊數: 203, 領域排名: 71.43%)

Behavior-selective apoptotic capacity of 4-(3,4,5-Trimethoxyphenoxy) benzoic acid and its methyl derivatives on two breast cancer cell lines.
KUAN‐HAN LEE, WEN‐YUEH HO, SHU‐JING WU, TSUNG‐LIN CHENG, PO‐JUI HUANG, CLAY C. C. WANG, JUI‐HSIANG HUNG* - - 1 - ANTICANCER RESEARCH - ANTICANCER RES 2014;34(4):1801-1809
(IF: 1.872, Journal Ranking: 145, Number of Journals of this Field: 203, Ranking: 71.43%)

43

RHBDL2是人類惡性上皮細胞具有抗失巢凋亡能力的關鍵細胞膜蛋白酶
鄭琮霖*, 賴昭翰, 江信仲, 洪瑞祥, 劉詩凱, 張碧英, 施桂月, 吳華林 - - 9 - Scientific World Journal - SCI WORLD J 2014 X卷(X期):Article ID 902987頁
(IF: 1.219, 領域排名: 16, 領域期刊數: 55, 領域排名: 29.09%)

RHBDL2 is a critical membrane protease for anoikis resistance in human malignant epithelial cells
Tsung-Lin Cheng*, Chao-Han Lai, Shinn-Jong Jiang, Jui‐Hsiang Hung, Shi-Kai Liu, Bi-Ing Chang, Guey-Yueh Shi, and Hua-Lin Wu - - 9 - Scientific World Journal - SCI WORLD J 2014;X(X):Article ID 902987
(IF: 1.219, Journal Ranking: 16, Number of Journals of this Field: 55, Ranking: 29.09%)

44

內質網壓力誘導肝癌細胞脫嘌呤核酸內切酶1過表達
鄭琮霖, Chen PS(共同第一), Li RH, 袁行修, Su IJ, Hung JH* - - 1 - International Journal of Molecular Sciences - INT J MOL SCI 2014 15卷(7期):12442-12457頁
(IF: 2.339, 領域排名: 52, 領域期刊數: 148, 領域排名: 35.14%)

Induction of apurinic endonuclease 1 overexpression by endoplasmic reticulum stress in hepatoma cells
Cheng TL, Chen PS, Li RH, Yuan SS, Su IJ, Hung JH - - 1 - International Journal of Molecular Sciences - INT J MOL SCI 2014;15(7):12442-12457
(IF: 2.339, Journal Ranking: 52, Number of Journals of this Field: 148, Ranking: 35.14%)

45

Baicalein Inhibits HMGB1 Release and MMP-2/-9 Expression in Lipopolysaccharide-Induced Cardiac Hypertrophy
陳懷民,劉淑芬,徐仲豪,陳贊如,鄭琮霖,邱肇基*,葉竹來* - - 1 - AMERICAN JOURNAL OF CHINESE MEDICINE - AM J CHINESR MED 2014 42卷(4期):785-797頁
(IF: 2.625, 領域排名: 3, 領域期刊數: 22, 領域排名: 13.64%)

Baicalein Inhibits HMGB1 Release and MMP-2/-9 Expression in Lipopolysaccharide-Induced Cardiac Hypertrophy
Huai-Min Chen, Shu-Fen Lioud, Jong-Hau Hsu, Tsan-Ju Cheng,Tsung-Lin Cheng, Chaw-Chi Chiu,Jwu-Lai Yeh - - 1 - AMERICAN JOURNAL OF CHINESE MEDICINE - AM J CHINESR MED 2014;42(4):785-797
(IF: 2.625, Journal Ranking: 3, Number of Journals of this Field: 22, Ranking: 13.64%)

46

凝血酶調節素調控角質細胞分化與促進傷口癒合
鄭琮霖 - - 1 - Journal of Investigative Dermatology - 2013 133卷(1期):1638–1645頁
(IF: 6.314, 領域排名: 1, 領域期刊數: 58, 領域排名: 1.72%)

Thrombomodulin Regulates Keratinocyte Differentiation and Promotes Wound Healing
Cheng TL, Wu YT, Lai CH, Kao YC, Kuo CH, Liu SL, Hsu YY, Chen PK, Cho CF, Wang KC, Lin WL, Chang BI, Chen CM, Weiler H, Shi GY, Wu HL* - - 1 - Journal of Investigative Dermatology - 2013;133(1):1638–1645
(IF: 6.314, Journal Ranking: 1, Number of Journals of this Field: 58, Ranking: 1.72%)

47

檸檬酸合成酶喪失直接聯繫腫瘤惡性化之瓦氏效應
鄭琮霖 - - 1 - Scientific Reports - 2012 2卷(1期):785頁
(IF: 2.927, 領域排名: 8, 領域期刊數: 56, 領域排名: 14.29%)

Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy
Lin CC#, Cheng TL#, Tsai WH, Tsai HJ, Hu KH, Chang HC, Yeh CW, Chen YC, Liao CC, Chang WT* (#equal contrubution) - - 1 - Scientific Reports - 2012;2(1):785
(IF: 2.927, Journal Ranking: 8, Number of Journals of this Field: 56, Ranking: 14.29%)

48

扁菱蛋白酶RHBDL2與凝血酶調節素於皮膚傷口癒合的功能
鄭琮霖 - - 1 - Journal of Investigative Dermatology - 2011 131卷(1期):2486-2494頁
(IF: 6.314, 領域排名: 1, 領域期刊數: 58, 領域排名: 1.72%)

Functions of Rhomboid Family Protease RHBDL2 and Thrombomodulin in Wound Healing
Cheng TL, Wu YT, Lin HY, Hsu FC, Liu SK, Chang BI, Chen WS, Lai CH, Shi GY*, Wu HL* - - 1 - Journal of Investigative Dermatology - 2011;131(1):2486-2494
(IF: 6.314, Journal Ranking: 1, Number of Journals of this Field: 58, Ranking: 1.72%)

49

利用頭尾串接之多重shRNA表現系統治療惡性癌細胞
鄭琮霖 - - 1 - Cancer Gene Therapy - 2009 16卷(1期):516-531頁
(IF: 2.945, 領域排名: 49, 領域期刊數: 159, 領域排名: 30.82%)

Multitarget therapy of malignant cancers by the head-to-tail tandem array multiple shRNAs expression system
Cheng TL, Teng CF, Tsai WH, Yeh CW, Wu MP, Hsu HC, Hung CF, Chang WT* - - 1 - Cancer Gene Therapy - 2009;16(1):516-531
(IF: 2.945, Journal Ranking: 49, Number of Journals of this Field: 159, Ranking: 30.82%)

50

粒線體標的序列的鑑別分析與人類檸檬酸合成酶機制探討
鄭琮霖 - - 1 - Journal of Cellular Biochemistry - 2009 107卷(1期):1002-1015頁
(IF: 3.062, 領域排名: 125, 領域期刊數: 290, 領域排名: 43.10%)

Identification and characterization of the mitochondrial targeting sequence and mechanism in human citrate synthase
Cheng TL, Liao CC, Tsai WH, Lin CC, Yeh CW, Teng CF, Chang WT* - - 1 - Journal of Cellular Biochemistry - 2009;107(1):1002-1015
(IF: 3.062, Journal Ranking: 125, Number of Journals of this Field: 290, Ranking: 43.10%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
113 — N 國科會(原科技部) — NSTC112-2314-B-037-101-MY2 — 1 個人型
研發提升凝血酶調節素表現以對抗骨關節炎的miRNA治療策略(2/2)( )
2024/08/01 ~ 2025/07/31
2
112 — N 國科會(原科技部) — NSTC112-2314-B-037-101-MY2 — 1 個人型
研發提升凝血酶調節素表現以對抗骨關節炎的miRNA治療策略(1/2)( )
2023/08/01 ~ 2025/07/31
3
112 — Z 大專學生研究計畫及博士後 — NSTC112-2811-B-037-021 — 9 博士後研究員
博士級研究人員--鄒亞璇( )
2023/08/01 ~ 2024/07/31
4
111 — N 國科會(原科技部) — MOST111-2314-B-037-055 — 1 個人型
軟骨細胞表現之凝血?調節素對骨關節炎和軟骨修復的研究_2( )
2022/08/01 ~ 2023/07/31
5
110 — N 國科會(原科技部) — MOST110-2314-B-037-022 — 1 個人型
軟骨細胞表現之凝血酶調節素對骨關節炎和軟骨修復的研究( )
2021/08/01 ~ 2022/10/31
6
109 — DK 前瞻重點(原校院) — KMU-DK(A)110003 —  
探討軟骨細胞表現之凝血酶調節素於骨關節炎與軟骨修復的角色( )
2021/01/01 ~ 2021/12/31
7
108 — N 國科會(原科技部) — MOST106-2314-B-037-009-MY3 — 1 個人型
研究成骨細胞表現之凝血酶調節素在糖尿病骨癒合所扮演的角色(3/3)( )
2019/08/01 ~ 2020/07/31
8
107 — N 國科會(原科技部) — MOST106-2314-B-037-009-MY3 — 1 個人型
研究成骨細胞表現之凝血酶調節素在糖尿病骨癒合所扮演的角色(2/3)( )
2018/08/01 ~ 2020/07/31
9
106 — N 國科會(原科技部) — MOST106-2314-B-037-009-MY3 — 1 個人型
研究成骨細胞表現之凝血酶調節素在糖尿病骨癒合所扮演的角色(1/3)( )
2017/08/01 ~ 2020/07/31
10
105 — M 高醫(種子計畫) — KMU-M106013 —  
探討凝血酶調節素在血纖維蛋白溶酶原調控皮膚傷口癒合中所扮演的角色( )
2017/01/01 ~ 2017/12/31
11
105 — TP 頂尖計畫(高醫) — KMU-TP105B14 —  
子計畫十四、研究凝血酶調節素於成骨細胞生理功能的角色( )
2016/11/01 ~ 2017/10/31
12
104 — N 國科會(原科技部) — MOST104-2320-B-037-026 — 1 個人型
研究凝血酶調節素於調控蝕骨細胞生成作用之功能( )
2015/08/01 ~ 2016/07/31
13
104 — TP 頂尖計畫(高醫) — KMU-TP104B13 —  
子計畫十三、研究凝血酶調節素與内皮唾酸蛋白之凝集素功能區在骨重塑過程中所扮演的角色( )
2015/10/01 ~ 2016/09/30
14
103 — N 國科會(原科技部) — MOST103-2320-B-037-022 — 1 個人型
探討扁菱蛋白酶RHBDL2在腫瘤細胞抗失巢凋亡作用中所扮演的角色( )
2014/08/01 ~ 2015/07/31
15
103 — TP 頂尖計畫(高醫) — KMU-TP103B10 —  
研究含有C 型類凝集素功能區之蛋白家族在骨重塑過程中所扮演的角色(Study the role of C-type lectin-like domain-containing (CLEC) family in bone remodeling)
2014/08/01 ~ 2015/07/31
16
102 — N 國科會(原科技部) — NSC102-2320-B-037-034 — 1 個人型
探討扁菱蛋白酶與其相關受質在糖尿病傷口癒合的角色-2( )
2013/08/01 ~ 2014/07/31
17
102 — Q 新聘教師計畫(校內) — KMU-Q103013 —  
探討凝血酶調節素於噬骨細胞生成作用中所扮演之角色( )
2014/01/01 ~ 2014/12/31

 Patent

NO Patent Name Country Certified Date Patent No
1 一種TMD1蛋白質用於製備發炎性骨流失藥物的用途 美國 2017/10/03 9,775,885
2 TMD1 蛋白用於治?骨質?失疾病 中華民國 2019/02/11 I650135