Education
School — Major — Degree | Duration |
---|---|
國立陽明大學 — 傳統醫藥研究所(畢) — 博士 Doctorate, Institute of Traditional Medicine, National Yang-Ming University |
2004/09 — 2008/02 |
高雄醫學大學 — 藥學研究所(畢) — 碩士 Master, , |
2002/09 — 2004/06 |
高雄醫學大學 — 藥學系(畢) — 學士 Bachelor, , |
1998/09 — 2002/06 |
Intramural Experience
Office/Department/Institute | Position | Duration |
---|---|---|
藥學系碩士班 Master's Program in Pharmacy | Director | 2024/08/01 — 2025/07/31 |
藥學系博士班 PhD Program in Pharmacy | Director | 2024/08/01 — 2025/07/31 |
藥學系 School of Pharmacy | Professor | 2023/02/01 — |
藥學系 School of Pharmacy | Associate Professor | 2017/02/01 — 2023/01/31 |
藥學系 School of Pharmacy | Assistant Professor | 2013/08/01 — 2017/01/31 |
Extramural Experience
Discipline
NO | Discipline | Expertise |
---|---|---|
1 | 生物醫農類 Biology, Medicine and Agriculture | 藥學及中醫藥 Pharmacy and Chinese Medicine and Pharmacy |
2 | 人文及社會科學類 Humanities and Social Sciences | 體育學 Physical Education |
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
Area(s) of Expertise & Research
臨床前動物試驗、產品劑型設計、口服吸收與藥動學評估、抗疲勞功效評估、主成分含量分析
Preclinical animal tests, delivery system design, oral absorption and pharmacokinetic evaluation, anti-fatigue assessment, quantification of active components
Publication
NO | Publication |
---|---|
1 | Determination of Synephrine and Caffeine in Citrus Species Herbal Medicines and Weight-Loss Supplements from Taiwan by High-Performance Liquid Chromatography (HPLC) Determination of Synephrine and Caffeine in Citrus Species Herbal Medicines and Weight-Loss Supplements from Taiwan by High-Performance Liquid Chromatography (HPLC) |
2 | Determination of chlorphenesin in cosmetics, a preservative that can affect anti-doping test result interpretations. Determination of chlorphenesin in cosmetics, a preservative that can affect anti-doping test result interpretations. |
3 | Formulation Approaches to Crystalline Status Modification for Carotenoids: Impacts on Dissolution, Stability, Bioavailability, and Bioactivities Formulation Approaches to Crystalline Status Modification for Carotenoids: Impacts on Dissolution, Stability, Bioavailability, and Bioactivities |
4 | 臺灣「運動禁藥查詢系統」行動應用程式之開發與進展 Development and Progress of Mobile App "Inquiry System for Prohibited Medicine in Sports" in Taiwan |
5 | Poly (Lactic-Co-Glycolic) Acid–Poly (Vinyl Pyrrolidone) Hybrid Nanoparticles to Improve the Efficiency of Oral Delivery of β-Carotene Poly (Lactic-Co-Glycolic) Acid–Poly (Vinyl Pyrrolidone) Hybrid Nanoparticles to Improve the Efficiency of Oral Delivery of β-Carotene |
6 | 迎接運動禁藥檢測的新篇章:指尖乾血點 Embracing a New Chapter of Anti-Doping Testing in Sports: Finger-Prick Dried Blood Spot |
7 | Self-Emulsifying Phospholipid Preconcentrates for the Enhanced Photoprotection of Luteolin Self-Emulsifying Phospholipid Preconcentrates for the Enhanced Photoprotection of Luteolin |
8 | Preparatory Conditions Optimization and Characterization of Hierarchical Porous Carbon from Seaweed as Carbon-Precursor Using a Box—Behnken Design for Application of Supercapacitor Preparatory Conditions Optimization and Characterization of Hierarchical Porous Carbon from Seaweed as Carbon-Precursor Using a Box—Behnken Design for Application of Supercapacitor |
9 | Nanoformulation Development to Improve the Biopharmaceutical Properties of Fisetin Using Design of Experiment Approach. Nanoformulation Development to Improve the Biopharmaceutical Properties of Fisetin Using Design of Experiment Approach. |
10 | Real-world experience of serial serum levels of GS-331007 in chronic hepatitis C hemodialysis patients during and after sofosbuvir/velpatasvir therapy. Real-world experience of serial serum levels of GS-331007 in chronic hepatitis C hemodialysis patients during and after sofosbuvir/velpatasvir therapy. |
11 | Chinese herbal medicine significantly impacts the haematological variables of the Athlete Biological Passport Chinese herbal medicine significantly impacts the haematological variables of the Athlete Biological Passport |
12 | Blood-to-muscle distribution and urinary excretion of higenamine in rats Blood-to-muscle distribution and urinary excretion of higenamine in rats |
13 | Effect of Quercetin on Injury to Indomethacin-Treated Human Embryonic Kidney 293 Cells Effect of Quercetin on Injury to Indomethacin-Treated Human Embryonic Kidney 293 Cells |
14 | Comparative biotransformation of luteolin and apigenin from the flower extract and the stem-and-leaf extract of Dendranthema morifolium Ramat. Tzvel. in rats. Comparative biotransformation of luteolin and apigenin from the flower extract and the stem-and-leaf extract of Dendranthema morifolium Ramat. Tzvel. in rats. |
15 | Potential Risk of Higenamine Misuse in Sports: Evaluation of Lotus Plumule Extract Products and a Human Study Potential Risk of Higenamine Misuse in Sports: Evaluation of Lotus Plumule Extract Products and a Human Study |
16 | Oral Bioavailability Enhancement and Anti-Fatigue Assessment of the Andrographolide Loaded Solid Dispersion Oral Bioavailability Enhancement and Anti-Fatigue Assessment of the Andrographolide Loaded Solid Dispersion |
17 | Self-Nanoemulsifying Drug Delivery Systems for Enhancing Solubility, Permeability, and Bioavailability of Sesamin. Self-Nanoemulsifying Drug Delivery Systems for Enhancing Solubility, Permeability, and Bioavailability of Sesamin. |
18 | Effect of Quercetin on Dexamethasone-Induced C2C12 Skeletal Muscle Cell Injury Effect of Quercetin on Dexamethasone-Induced C2C12 Skeletal Muscle Cell Injury |
19 | Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats. Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats. |
20 | 2019 未來科技展 「運動禁藥一手掌握 & 抗炎保胃讚」 2019 未來科技展 「運動禁藥一手掌握 & 抗炎保胃讚」 |
21 | Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide |
22 | Repressed exercise-induced hepcidin levels after Danggui Buxue Tang supplementation in male recreational runners Repressed exercise-induced hepcidin levels after Danggui Buxue Tang supplementation in male recreational runners |
23 | Determination of cannabinoids in hemp nut products in Taiwan by HPLC-MS/MS coupled with chemometric analysis: quality evaluation and a pilot human study Determination of cannabinoids in hemp nut products in Taiwan by HPLC-MS/MS coupled with chemometric analysis: quality evaluation and a pilot human study |
24 | Rapid determination of oxindole alkaloids in Cat's claw by HPLC using ionic liquid-based microwave-assisted extraction and silica monolithic column Rapid determination of oxindole alkaloids in Cat's claw by HPLC using ionic liquid-based microwave-assisted extraction and silica monolithic column |
25 | Self-Nanoemulsifying Drug Delivery System for Resveratrol: Enhanced Oral Bioavailability and Reduced Physical Fatigue in Rats Self-Nanoemulsifying Drug Delivery System for Resveratrol: Enhanced Oral Bioavailability and Reduced Physical Fatigue in Rats |
26 | Microwave-Assisted Extraction of Cannabinoids in Hemp Nut Using Response Surface Methodology: Optimization and Comparative Study Microwave-Assisted Extraction of Cannabinoids in Hemp Nut Using Response Surface Methodology: Optimization and Comparative Study |
27 | Development of a solid dispersion system for improving the oral bioavailability of resveratrol in rats Development of a solid dispersion system for improving the oral bioavailability of resveratrol in rats |
28 | Enhanced solubility, dissolution, and absorption of lycopene by a solid dispersion technique: The dripping pill delivery system Enhanced solubility, dissolution, and absorption of lycopene by a solid dispersion technique: The dripping pill delivery system |
29 | Acute Garcinia mangostana (mangosteen) supplementation does not alleviate physical fatigue during exercise: a randomized, double-blind, placebo-controlled, crossover trial. Acute Garcinia mangostana (mangosteen) supplementation does not alleviate physical fatigue during exercise: a randomized, double-blind, placebo-controlled, crossover trial. |
30 | Protective effects of the roots of Angelica sinensis on strenuous exercise-induced sports anemia in rats Protective effects of the roots of Angelica sinensis on strenuous exercise-induced sports anemia in rats |
31 | A Hydrogel-Based Epirubicin Delivery System for Intravesical Chemotherapy A Hydrogel-Based Epirubicin Delivery System for Intravesical Chemotherapy |
32 | Bioanalytical Method Development Using Liquid Chromatography with Amperometric Detection for the Pharmacokinetic Evaluation of Forsythiaside in Rats Bioanalytical Method Development Using Liquid Chromatography with Amperometric Detection for the Pharmacokinetic Evaluation of Forsythiaside in Rats |
33 | HPLC Determination of Lansoprazole and Method Application for the Formulation Development of Enteric-coated Lansoprazole Pellets HPLC Determination of Lansoprazole and Method Application for the Formulation Development of Enteric-coated Lansoprazole Pellets |
34 | Determination of rhynchophylline and hirsutine in rat plasma by UPLC-MS/MS after oral administration of Uncaria rhynchophylla extract Determination of rhynchophylline and hirsutine in rat plasma by UPLC-MS/MS after oral administration of Uncaria rhynchophylla extract |
35 | Pharmacokinetics and oral bioavailability of epimedin C after oral administration of epimedin C and Herba Epimedii extract in rats Pharmacokinetics and oral bioavailability of epimedin C after oral administration of epimedin C and Herba Epimedii extract in rats |
36 | Development of HPLC with Photo-diode Array Method for the Determination of Ramipril in Tablets Using Factorial Design Development of HPLC with Photo-diode Array Method for the Determination of Ramipril in Tablets Using Factorial Design |
37 | 淫羊藿之草藥-藥品相互作用對於Sildenafil的藥動學影響 Herb-Drug Interaction of Epimedium sagittatum (Sieb. et Zucc.) Maxim Extract on the Pharmacokinetics of Sildenafil in Rats. |
38 | Interaction of Acupuncture and Electroacupuncture on the Pharmacokinetics of Aspirin and the Effect of Brain Blood Flow in Rats Interaction of Acupuncture and Electroacupuncture on the Pharmacokinetics of Aspirin and the Effect of Brain Blood Flow in Rats |
39 | Oseltamivir和oseltamivir carboxylic acid於懷孕大鼠之化學分析與胎盤通透 Chemical analysis and transplacental transfer of oseltamivir and oseltamivir carboxylic acid in pregnant rats. |
40 | Cranial neurotransmitter alteration in newborn piglets exposed to oxygen Cranial neurotransmitter alteration in newborn piglets exposed to oxygen |
41 | Correlation between radioactivity and chemotherapeutics of the (111)In-VNB-liposome in pharmacokinetics and biodistribution in rats. Correlation between radioactivity and chemotherapeutics of the (111)In-VNB-liposome in pharmacokinetics and biodistribution in rats. |
42 | Pharmacokinetics and urine metabolite identification of dehydroevodiamine in the rat. Pharmacokinetics and urine metabolite identification of dehydroevodiamine in the rat. |
43 | Efficacy of intratracheal instillation of a meropenem/perfluorochemical suspension in acute lung injury. Efficacy of intratracheal instillation of a meropenem/perfluorochemical suspension in acute lung injury. |
44 | Biological analysis of herbal medicines used for the treatment of liver diseases. Biological analysis of herbal medicines used for the treatment of liver diseases. |
45 | In vitro and in vivo methods to measure the ceftriaxone distribution into the rat tail intervertebral disc. In vitro and in vivo methods to measure the ceftriaxone distribution into the rat tail intervertebral disc. |
46 | Comparison in purity and antitumor effect of brand and generic paclitaxel against human ovarian cancer cells by an in vitro experimental model. Comparison in purity and antitumor effect of brand and generic paclitaxel against human ovarian cancer cells by an in vitro experimental model. |
47 | Analysis of biliary excretion of icariin in rats. Analysis of biliary excretion of icariin in rats. |
48 | Effects of a P-glycoprotein modulator on the pharmacokinetics and distribution of free levobupivacaine and bupivacaine in rats. Effects of a P-glycoprotein modulator on the pharmacokinetics and distribution of free levobupivacaine and bupivacaine in rats. |
49 | Herb-drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats. Herb-drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats. |
50 | Oral bioavailability, urinary excretion and organ distribution of melamine in Sprague-Dawley rats by high-performance liquid chromatography with tandem mass spectrometry. Oral bioavailability, urinary excretion and organ distribution of melamine in Sprague-Dawley rats by high-performance liquid chromatography with tandem mass spectrometry. |
51 | Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats. Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats. |
52 | Determination of melamine in rat plasma, liver, kidney, spleen, bladder and brain by liquid chromatography-tandem mass spectrometry. Determination of melamine in rat plasma, liver, kidney, spleen, bladder and brain by liquid chromatography-tandem mass spectrometry. |
53 | Distribution of blood-muscle for clenbuterol in rat using microdialysis. Distribution of blood-muscle for clenbuterol in rat using microdialysis. |
54 | Measurement of free hydroxytyrosol in microdialysates from blood and brain of anesthetized rats by liquid chromatography with fluorescence detection. Measurement of free hydroxytyrosol in microdialysates from blood and brain of anesthetized rats by liquid chromatography with fluorescence detection. |
Project
NO |
YEAR — Source — No — Type
Project Name
|
Duration |
---|---|---|
1 |
113 — N 國科會(原科技部) — NSTC112-2410-H-037-016-MY2 — 1 個人型
探討補充芝麻與乳清蛋白緩解劇烈運動引起貧血之功效:提升口服鐵吸收的策略與對於鐵調素調控的影響(2/2)( )
|
2024/08/01 ~ 2025/07/31 |
2 |
112 — N 國科會(原科技部) — NSTC112-2410-H-037-016-MY2 — 1 個人型
探討補充芝麻與乳清蛋白緩解劇烈運動引起貧血之功效:提升口服鐵吸收的策略與對於鐵調素調控的影響(1/2)( )
|
2023/08/01 ~ 2025/07/31 |
3 |
111 — N 國科會(原科技部) — MOST110-2410-H-037-008-MY2 — 1 個人型
補充奈米化貝他胡蘿蔔素對運動過程週邊和中樞疲勞的作用與機制探討(2/2)( )
|
2022/08/01 ~ 2023/07/31 |
4 |
111 — Z 大專學生研究計畫及博士後 — NSTC112-2813-C-037-071-B — 8 大專學生研究計畫
112年度大專學生研究計畫-顏宇秀(藥學4)( )
|
2023/07/01 ~ 2024/02/29 |
5 |
110 — KK 高科大高醫產學合作補助 — —
基於藥物/天然產物功能化碳雜化納米複合材料之新型抗菌劑開發( )
|
2021/11/05 ~ 2022/11/04 |
6 |
110 — N 國科會(原科技部) — MOST110-2410-H-037-008-MY2 — 1 個人型
補充奈米化貝他胡蘿蔔素對運動過程週邊和中樞疲勞的作用與機制探討(1/2)( )
|
2021/08/01 ~ 2023/07/31 |
7 |
109 — N 國科會(原科技部) — MOST109-2410-H-037-018 — 1 個人型
蓮子心與去甲烏藥鹼對運動表現的影響-食用風險評估、作用機制與藥物動力學探討(2/2)( )
|
2020/08/01 ~ 2021/07/31 |
8 |
108 — H 衛福部 — MOHW109-CMAP-M-114-000406 —
建立中藥濃縮製劑藥典品質規範( )
|
2020/02/13 ~ 2020/12/31 |
9 |
108 — N 國科會(原科技部) — MOST108-2410-H-037-021 — 1 個人型
蓮子心與去甲烏藥鹼對運動表現的影響-食用風險評估、作用機制與藥物動力學探討(1/2)( )
|
2019/08/01 ~ 2020/07/31 |
10 |
106 — N 國科會(原科技部) — MOST106-2113-M-037-012 — 1 個人型
開發有機金屬化合物結合碳奈米材料之修飾電極並應用於測定草藥製品與人類尿液中之大麻素( )
|
2017/08/01 ~ 2018/07/31 |
11 |
104 — N 國科會(原科技部) — MOST103-2113-M-037-004-MY2 — 1 個人型
開發液相層析電化學分析方法應用於連翹和金銀花之藥動學與奈米配方設計(2/2)( )
|
2015/08/01 ~ 2016/07/31 |
12 |
104 — TP 頂尖計畫(高醫) — KMU-TP104A47 —
平台十四、新藥臨床前藥物動力學分析平台( )
|
2016/05/01 ~ 2016/09/30 |
13 |
103 — N 國科會(原科技部) — MOST103-2113-M-037-004-MY2 — 1 個人型
開發液相層析電化學分析方法應用於連翹和金銀花之藥動學與奈米配方設計(1/2)( )
|
2014/08/01 ~ 2016/07/31 |
14 |
103 — Q 新聘教師計畫(校內) — KMU-Q104010 —
貓爪藤新劑型之藥動學評估( )
|
2015/01/01 ~ 2015/12/31 |
15 |
102 — Q 新聘教師計畫(校內) — KMU-Q103020 —
開發鉤藤生物鹼的分析方法以應用於微透析取樣的可行性評估和製劑分析( )
|
2014/01/01 ~ 2014/12/31 |