Education
| School — Major — Degree | Duration |
|---|---|
|
高雄醫學大學 — 藥學系(畢) — 博士 Doctorate, School of Pharmacy, Kaohsiung Medical University |
2002/09 — 2008/06 |
|
高雄醫學大學 — 天然藥物研究所(畢) — 碩士 Master, Graduate Institute of Natural Products, Kaohsiung Medical University |
2000/09 — 2002/06 |
|
嘉南藥學專科學校 — 藥學科(畢) — 五專 Five-year college, Department of Pharmacy, Chia Nan University of Pharmacy ＆ Science |
1989/09 — 1995/06 |
Intramural Experience
| Office/Department/Institute | Position | Duration |
|---|---|---|
| 藥學科 | Pharmacist | — |
| 藥學系 School of Pharmacy | Professor | 2023/08/01 — |
| 香粧品學系 Department of Fragrance and Cosmetic Science | Professor | 2021/08/01 — 2023/07/31 |
| 藥學系 School of Pharmacy | Professor | 2020/02/01 — 2021/07/31 |
| 藥學系 School of Pharmacy | Associate Professor | 2016/03/01 — 2020/01/31 |
| 藥學系 School of Pharmacy | Assistant Professor | 2013/02/01 — 2016/02/29 |
Extramural Experience
Discipline
| NO | Discipline | Expertise |
|---|---|---|
| 1 | 生物醫農類 Biology, Medicine and Agriculture | 藥學及中醫藥 Pharmacy and Chinese Medicine and Pharmacy |
| 2 | 自然科學類 Natural Sciences | 化學 Chemistry |
Research & Technology Platform Open to the Outside
Interested Area(s)for Interdisciplinary Research
小分子化合物活性篩選與探討分子藥理活性機轉
compounds with specific activity on a screening assay and molecular mechanism of action
Area(s) of Expertise & Research
有機合成,藥物化學,藥物設計,化合物抗癌活性評估
organic synthesis, medicinal chemistry, drug design, anticancer assay
Publication
| NO | Publication |
|---|---|
| 1 | Novel 3-phenylquinoxalinylchalcone derivatives induce apoptosis, suppress cellular motility, and negatively regulate GPx4 for breast cancer therapy Novel 3-phenylquinoxalinylchalcone derivatives induce apoptosis, suppress cellular motility, and negatively regulate GPx4 for breast cancer therapy |
| 2 | Electrospun PVP/HPBCD nanofiber topical drug delivery platform for enhanced skin permeability and anti-pollution bioactivity of extract. Electrospun PVP/HPBCD nanofiber topical drug delivery platform for enhanced skin permeability and anti-pollution bioactivity of extract. |
| 3 | 4-Anilinoquinolinylchalcone 之衍生物經ERK/MRTF - A對於抗纖維化之影響 4-Anilinoquinolinylchalcone derivatives mediate 1 antifibrotic effects through 2 ERK/MRTF - A signaling pathway crosstalk. 3 |
| 4 | A chalcone/quinolone hybrid drug (COQM) triggers oxidative stress, DNA damage, and apoptosis to induce selective antiproliferative effects in breast cancer cells A chalcone/quinolone hybrid drug (COQM) triggers oxidative stress, DNA damage, and apoptosis to induce selective antiproliferative effects in breast cancer cells |
| 5 | Skin delivery of synthetic benzoyl pterostilbenes suppresses atopic dermatitis-like inflammation through the inhibition of keratinocyte and macrophage activation. Skin delivery of synthetic benzoyl pterostilbenes suppresses atopic dermatitis-like inflammation through the inhibition of keratinocyte and macrophage activation. |
| 6 | 合成與抗癌評估4-Anilinoquinolinylchalcone Synthesis and Anticancer Evaluation of 4-Anilinoquinolinylchalcone Derivatives |
| 7 | Myricetin Nanofibers Enhanced Water Solubility and Skin Penetration for Increasing Antioxidant and Photoprotective Activities. Myricetin Nanofibers Enhanced Water Solubility and Skin Penetration for Increasing Antioxidant and Photoprotective Activities. |
| 8 | Determination of the Bacterial Community of Mustard Pickle Products and Their Microbial and Chemical Qualities. Determination of the Bacterial Community of Mustard Pickle Products and Their Microbial and Chemical Qualities. |
| 9 | A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage. A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage. |
| 10 | Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis. Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis. |
| 11 | Effect of High-Pressure Treatment on Blue Marlin (Makaira nigricans) Quality During Storage Effect of High-Pressure Treatment on Blue Marlin (Makaira nigricans) Quality During Storage |
| 12 | Effects of high-hydrostatic-pressure processing on the chemical and microbiological quality of raw ready-to-eat hard clam marinated in soy sauce during cold storage Effects of high-hydrostatic-pressure processing on the chemical and microbiological quality of raw ready-to-eat hard clam marinated in soy sauce during cold storage |
| 13 | The effectiveness of synthetic methoxylated isoflavones in delivering to the skin and alleviating psoriasiform lesions via topical absorption The effectiveness of synthetic methoxylated isoflavones in delivering to the skin and alleviating psoriasiform lesions via topical absorption |
| 14 | Inhibitory Effects of High-Hydrostatic-Pressure Processing on Growth and Histamine Formation of Histamine-Forming Bacteria in Yellowfin Tuna Meat during Storage Inhibitory Effects of High-Hydrostatic-Pressure Processing on Growth and Histamine Formation of Histamine-Forming Bacteria in Yellowfin Tuna Meat during Storage |
| 15 | Quality Improvement in Mackerel Fillets Caused by Brine Salting Combined with High-Pressure Processing Quality Improvement in Mackerel Fillets Caused by Brine Salting Combined with High-Pressure Processing |
| 16 | Antioxidant, Anti-Inflammation and Antiaging Activities of Artocarpus altilis Methanolic Extract on Urban Particulate Matter-Induced HaCaT Keratinocytes Damage Antioxidant, Anti-Inflammation and Antiaging Activities of Artocarpus altilis Methanolic Extract on Urban Particulate Matter-Induced HaCaT Keratinocytes Damage |
| 17 | 發現三唑沙利度胺衍生物作為抗纖維化藥劑 Discovery of triazolyl thalidomide derivatives as anti-fibrosis agents |
| 18 | Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure-Activity Relationship Analysis. Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure-Activity Relationship Analysis. |
| 19 | Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization |
| 20 | Topical Artocarpus communis Nanoparticles Improved the Water Solubility and Skin Permeation of Raw A. communis Extract, Improving Its Photoprotective Effect Topical Artocarpus communis Nanoparticles Improved the Water Solubility and Skin Permeation of Raw A. communis Extract, Improving Its Photoprotective Effect |
| 21 | Pterostilbene Attenuates Particulate Matter-Induced Oxidative Stress, Inflammation and Aging in Keratinocytes Pterostilbene Attenuates Particulate Matter-Induced Oxidative Stress, Inflammation and Aging in Keratinocytes |
| 22 | Synthetic Naphthofuranquinone Derivatives Are Effective in Eliminating Drug-Resistant Candida albicans in Hyphal, Biofilm, and Intracellular Forms: An Application for Skin-Infection Treatment Synthetic Naphthofuranquinone Derivatives Are Effective in Eliminating Drug-Resistant Candida albicans in Hyphal, Biofilm, and Intracellular Forms: An Application for Skin-Infection Treatment |
| 23 | Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes |
| 24 | Discovery of 4-Anilinoquinolinylchalcone Derivatives as Potential NRF2 Activators. Discovery of 4-Anilinoquinolinylchalcone Derivatives as Potential NRF2 Activators. |
| 25 | Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo |
| 26 | Phytochemical Naphtho[1,2-b] furan-4,5-dione Induced Topoisomerase II-mediated DNA Damage Response in Human Non-small-Cell Lung Cancer Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer. |
| 27 | Liposomal Avicequinone-B formulations: Aqueous solubility, physicochemical properties and apoptotic effects on cutaneous squamous cell carcinoma cells Liposomal Avicequinone-B formulations: Aqueous solubility, physicochemical properties and apoptotic effects on cutaneous squamous cell carcinoma cells |
| 28 | Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection |
| 29 | Improvement of skin penetration, antipollutant activity and skin hydration of 7,3′,4′- trihydroxyisoflavone cyclodextrin inclusion complex Improvement of skin penetration, antipollutant activity and skin hydration of 7,3′,4′- trihydroxyisoflavone cyclodextrin inclusion complex |
| 30 | Design, synthesis, and anti-bacterial evaluation of triazolyl-pterostilbene derivatives Design, synthesis, and anti-bacterial evaluation of triazolyl-pterostilbene derivatives |
| 31 | Discovery of 3-Arylquinoxaline Derivatives as Potential Anti-Dengue Virus Agents Discovery of 3-Arylquinoxaline Derivatives as Potential Anti-Dengue Virus Agents |
| 32 | Discovery of 2-Substituted 3-Arylquinoline Derivatives as Potential Anti-Inflammatory Agents Through Inhibition of LPS-Induced Inflammatory Responses in Macrophages. Discovery of 2-Substituted 3-Arylquinoline Derivatives as Potential Anti-Inflammatory Agents Through Inhibition of LPS-Induced Inflammatory Responses in Macrophages. |
| 33 | Discovery of naphtho[1,2-d]oxazole derivatives as potential anti-HCV agents through inducing heme oxygenase-1 expression Discovery of naphtho[1,2-d]oxazole derivatives as potential anti-HCV agents through inducing heme oxygenase-1 expression |
| 34 | Discovery of pyrazolo[4,3-c]quinolines derivatives as potential anti-inflammatory agents through inhibiting of NO production Discovery of pyrazolo[4,3-c]quinolines derivatives as potential anti-inflammatory agents through inhibiting of NO production |
| 35 | Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents Synthesis and Biological Evaluation of Thalidomide Derivatives as Potential Anti-Psoriasis Agents |
| 36 | Discovery of 3-amino-2-hydroxypropoxyisoflavone derivatives as potential anti-HCV agents Discovery of 3-amino-2-hydroxypropoxyisoflavone derivatives as potential anti-HCV agents |
| 37 | Preparation, characterizations and anti-pollutant activity of 7,3′,4′-trihydroxyisoflavone nanoparticles in particulate matter- induced HaCaT keratinocytes Preparation, characterizations and anti-pollutant activity of 7,3′,4′-trihydroxyisoflavone nanoparticles in particulate matter- induced HaCaT keratinocytes |
| 38 | 9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1,2-c]quinolin-11-one (BPIQ), a quinoline derivative inhibits human hepatocellular carcinoma cells by inducing ER stress and apoptosis. 9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1,2-c]quinolin-11-one (BPIQ), a quinoline derivative inhibits human hepatocellular carcinoma cells by inducing ER stress and apoptosis. |
| 39 | Dual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cells. Dual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cells. |
| 40 | Discovery of Indeno[1,2-c]quinoline Derivatives as Potent Dual Antituberculosis and Anti-Inflammatory Agents Discovery of Indeno[1,2-c]quinoline Derivatives as Potent Dual Antituberculosis and Anti-Inflammatory Agents |
| 41 | Naphtho[1,2-b]furan-4,5-dione is a potent anti-MRSA agent against planktonic, biofilm, and intracellular bacteria Naphtho[1,2-b]furan-4,5-dione is a potent anti-MRSA agent against planktonic, biofilm, and intracellular bacteria |
| 42 | Pterostilbene, a methoxylated resveratrol derivative, efficiently eradicates planktonic, biofilm, and intracellular MRSA by topical application Pterostilbene, a methoxylated resveratrol derivative, efficiently eradicates planktonic, biofilm, and intracellular MRSA by topical application |
| 43 | Discovery of novel diarylpyrazolylquinoline derivatives as potent anti-dengue virus agents Discovery of novel diarylpyrazolylquinoline derivatives as potent anti-dengue virus agents |
| 44 | Specific inhibition of bacterial -glucuronidase by pyrazolo[4,3-c]quinoline derivatives via a pH-dependent manner to suppress chemotherapy-induced intestinal toxicity Specific inhibition of bacterial -glucuronidase by pyrazolo[4,3-c]quinoline derivatives via a pH-dependent manner to suppress chemotherapy-induced intestinal toxicity |
| 45 | 探索indeno[1,2-b]quinoxaline 衍生物成為具有潛力之抗癌藥劑 Discovery of indeno[1,2-b]quinoxaline derivatives as potential anticancer agents |
| 46 | 以酸性依賴性聚合物包覆7,3′,4′-trihydroxyisoflavone之奈米顆粒製劑作為外用給藥系統 Design of acid-responsive polymeric nanoparticles for 7,3′,4′-trihydroxyisoflavone topical administration |
| 47 | TCH1036, a indeno[1,2-c]quinoline derivative, potentially inhibited the growth of human brain malignant glioma (GBM) 8401 cells via suppression of the expression of Suv39h1 and PARP TCH1036, a indeno[1,2-c]quinoline derivative, potentially inhibited the growth of human brain malignant glioma (GBM) 8401 cells via suppression of the expression of Suv39h1 and PARP |
| 48 | Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species |
| 49 | 探索2-[2-(5-nitrofuran-2-yl)vinyl]quinoline 為新型抗腫瘤轉移藥劑 Discovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents |
| 50 | 探索Benzo[f]indole-4,9-dione衍生物為新型抗發炎藥劑 Discovery of Benzo[f]indole-4,9-dione Derivatives as New Types of Anti-Inflammatory Agents |
| 51 | 探索新型N-alkyl 4-anilinofuro[2,3-b]quinoline (CIL-102)衍生物對前列腺癌細胞之作用 Discovery of Novel N-alkyl 4-anilinofuro[2,3-b]quinoline Derivatives (CIL-102 Derivatives) Against Castration-Resistant Human Prostate Cancers |
| 52 | 探索3-phenylquinolinylchalcone衍生物具有選擇性抗乳癌之潛力藥物 Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers |
| 53 | Naphtho[1,2-b]furan-4,5-dione藉由抑制 Src-mediated 信號途徑抑制 MDA-MB-231 細胞遷移和侵襲 Naphtho[1,2-b]furan-4,5-dione inhibits MDA-MB-231 cell migration and invasion by suppressing Src-mediated signaling pathways |
| 54 | 合成2-aroyl-3-arylquinoline衍生物並評估其抗增生與抗登革病毒活性 Synthesis, antiproliferative and anti-dengue virus evaluations of 2-aroyl-3-arylquinoline derivatives. |
| 55 | Furano-1,2-Naphthoquinone 抑制 Ca9-22 人類口腔鱗癌細胞之Src 和 PI3K/Akt 信號途徑。 Furano-1,2-Naphthoquinone Inhibits Src and PI3K/Akt Signaling Pathways in Ca9-22 Human Oral Squamous Carcinoma Cells. |
| 56 | 合成9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c] quinoline-11-one衍生物並評估其抗增生活性-第四部分 Synthesis and antiproliferative evaluation of 9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c] quinoline-11-one derivatives. Part 4. |
| 57 | NFD 對於肝細胞生長因子誘導 MDA-MB-231 細胞的遷移與侵襲之抑制作用：作用機制 Inhibitory action of naphtho[1,2-b]furan-4,5-dione on hepatocyte growth factor-induced migration and invasion of MDA-MB-231 cells: Mechanisms of action |
| 58 | 合成3-phenylquinolinylchalcone 衍生物並評估其抗肺癌與抗乳癌活性 Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers |
| 59 | 合成β-lapachone 衍生物並評估其抗發炎活性 Synthesis and anti-inflammatory evaluations of β-lapachone derivatives |
| 60 | NFD經由抑制EGF/EGFR活化而阻斷乳癌細胞轉移的作用和機制 Inhibition of EGF/EGFR activation with naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of MDA-MB-231 cells |
| 61 | TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells |
| 62 | 合成Aminoalkoxy 4,5-Diphenylisoxazole 作為抗骨質疏鬆試劑 Synthesis of Aminoalkoxy Substituted 4,5-Diphenylisoxazole Derivatives as Potential Anti-osteoporotic Agents |
| 63 | 探索Indeno[1,2-c]quinoline衍生物作為拓樸異構酶I&II抑制劑,第三部份 Discovery of indeno[1, 2 - c] quinoline derivatives as dual topoisomerases I/II inhibitors: part 3 |
| 64 | 確認furo[3', 2':3,4]naphtho[1,2-d]imidazole 衍生物為口服mPGES-1抑制劑 Identification of furo[3', 2':3,4]naphtho[1,2-d]imidazole derivatives as orally active and selective inhibitors of microsomal prostaglandin E(2) synthase-1 (mPGES-1) |
| 65 | 合成6-substituted 9-methoxy-11H-indeno[1,2-c]quinoline-11-one為具有潛力之抗癌試劑 Synthesis of 6-substituted 9-methoxy-11H-indeno[1,2-c]quinoline-11-one derivatives as potential anticancer agents |
| 66 | Combretastatin A-4衍生物:合成2,4,5-triaryl-1H-imidazoles為抗肺癌H1299試劑 Combretastatin A-4 derivatives: synthesis and evaluation of 2,4,5-triaryl-1H-imidazoles as potential agents against H1299 (non-small cell lung cancer cell) |
| 67 | 發現Indeno[1,2-c]quinoline衍生物經由RANKL抑制蝕骨細胞增生 Discovery of indeno[1,2-c]quinoline derivatives as inhibitors of osteoclastogenesis induced by receptor activator of NF-κB ligand (RANKL) |
| 68 | 2,3-diarylquinoline 衍生物之合成以及抗增生之研究 Synthesis and antiproliferative evaluation of 2,3-diarylquinoline derivatives |
| 69 | 6-aryl-11-iminoindeno[1,2-c]quinoline 衍生物合成與抗增生活性評估 Synthesis and antiproliferative evaluation of 6-aryl-11-iminoindeno[1,2-c]quinoline derivatives |
| 70 | 發現4-anilinofuro[2,3-b]quinoline 衍生物為口服抗肺癌試劑 Discovery of 4-anilinofuro[2,3-b]quinoline derivatives as selective and orally active compounds against non-small-cell lung cancers |
| 71 | Indeno[1,2-c]quinoline類衍生物的合成與抗增生活性評估-第二報 Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2 |
| 72 | 確認benzofuro[2,3-b]quinoline 衍生物為抗肺結核試劑 Identification of benzofuro[2,3-b]quinoline derivatives as a new class of antituberculosis agents |
| 73 | Furo[3',2':3,4]naphtho[1,2-d]imidazole衍生物為敗血症抗發炎抑制劑 Furo[3',2':3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis. |
| 74 | 3-amino-2-hydroxypropoxyisoflavone衍生物的合成與抗骨質疏鬆活性評估 Synthesis and anti-osteoporotic evaluation of certain 3-amino-2-hydroxypropoxyisoflavone derivatives |
| 75 | 6-arylindeno[1,2-c]quinoline衍生物的合成與抗增生活性評估 Synthesis and antiproliferative evaluation of 6-arylindeno[1,2-c]quinoline derivatives |
| 76 | indeno[1,2-c]quinoline 衍生物的合成與抗增生活性評估 Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives |
| 77 | 4-anilino-8-methoxy-2-phenylquinoline 與 4-anilino-8-hydroxy-2-phenylquinoline衍生物合成及抗增生活性評估 Synthesis and antiproliferative evaluation of certain 4-anilino-8-methoxy-2-phenylquinoline and 4-anilino-8-hydroxy-2-phenylquinoline derivatives |
Project
| NO |
YEAR — Source — No — Type
Project Name
|
Duration |
|---|---|---|
| 1 |
115 — N 國科會(原科技部) — NSTC115-2320-B-037-011 — 1 個人型
開發二苯乙烯衍生物作為芳烴受體調節劑用於治療發炎性皮膚病( )
|
2026/08/01 ~ 2027/07/31 |
| 2 |
115 — NK 高醫-中山合作計畫 — — 1 個人型
探討萘並[1,2-d]噁唑衍生物 CCL-7268r 之抗氧化機制及其作為潛力抗衰老藥物的可能性(Exploration of the antioxidant mechanism of naphtho[1,2-d]oxazole derivative CCL-7268r and its potential as a promising anti-aging agent)
|
2026/01/01 ~ 2026/12/31 |
| 3 |
114 — KK 高科大高醫產學合作補助 — — 3 產學合作
應用高靜水壓技術提高蒜泥產品的藥理活性與保存性( )
|
2026/01/01 ~ 2026/12/31 |
| 4 |
114 — N 國科會(原科技部) — NSTC114-2320-B-037-024 — 1 個人型
設計合成紫檀芪衍生物用於治療皮膚發炎疾病( )
|
2025/08/01 ~ 2026/07/31 |
| 5 |
114 — Z 大專學生研究計畫及博士後 — NSTC115-2813-C-037-038-B — 8 大專學生研究計畫
115年度大專學生研究計畫-萬浚瑋(藥學3)( )
|
2026/07/01 ~ 2027/02/28 |
| 6 |
113 — N 國科會(原科技部) — MOST111-2320-B-037-021-MY3 — 1 個人型
設計合成萘醌衍生物用於治療抗藥性白色念珠菌感染(3/3)( )
|
2024/08/01 ~ 2025/07/31 |
| 7 |
112 — N 國科會(原科技部) — MOST111-2320-B-037-021-MY3 — 1 個人型
設計合成萘醌衍生物用於治療抗藥性白色念珠菌感染(2/3)( )
|
2023/08/01 ~ 2025/07/31 |
| 8 |
112 — NK 高醫-中山合作計畫 — — 1 個人型
利用分子動態模擬解析與早發性帕金森氏症相關的PINK1蛋白的四個單點突變造成PINK1激酶失去活性的原因(A Molecular Modeling Study on Four PINK1 Point Mutations Related to The Early Onset Parkinson’s Disease)
|
2023/01/01 ~ 2023/12/31 |
| 9 |
112 — Z 大專學生研究計畫及博士後 — NSTC112-2811-B-037-023 — 9 博士後研究員
博士級研究人員--楊淳茵( )
|
2023/10/01 ~ 2024/07/31 |
| 10 |
111 — KK 高科大高醫產學合作補助 — —
高靜水壓結合鹽水漬改良鯖魚片之品質及降低鯖魚肉過敏原之應用( )
|
2022/11/01 ~ 2023/10/31 |
| 11 |
111 — N 國科會(原科技部) — MOST111-2320-B-037-021-MY3 — 1 個人型
設計合成萘醌衍生物用於治療抗藥性白色念珠菌感染(1/3)( )
|
2022/08/01 ~ 2025/07/31 |
| 12 |
110 — KK 高科大高醫產學合作補助 — —
以高靜水壓技術提升台灣貝類之食用安全性與生物活性( )
|
2021/11/05 ~ 2022/11/04 |
| 13 |
110 — M 高醫(種子計畫) — KMU-M111005 —
設計與合成新型抗藥性白色念珠菌和生物膜形成的抑制劑( )
|
2022/01/01 ~ 2022/12/31 |
| 14 |
109 — KI 高醫國衛院 — KMU-KI110003 —
罕見疾病家族性腸息肉症(FAP)標靶藥物TCH-3511之Non-GLP藥理與毒理分析( )
|
2020/08/01 ~ 2021/07/31 |
| 15 |
109 — N 國科會(原科技部) — MOST108-2320-B-037-026-MY2 — 1 個人型
設計合成雜環化合物作為登革病毒複製的抑制劑(2/2)( )
|
2020/08/01 ~ 2021/07/31 |
| 16 |
108 — N 國科會(原科技部) — MOST108-2320-B-037-026-MY2 — 1 個人型
設計合成雜環化合物作為登革病毒複製的抑制劑(1/2)( )
|
2019/08/01 ~ 2021/07/31 |
| 17 |
107 — N 國科會(原科技部) — MOST107-2320-B-037-015 — 1 個人型
設計合成含有1,2,3-三唑結構的雜環化合物作為抗登革病毒藥( )
|
2018/08/01 ~ 2019/07/31 |
| 18 |
107 — Z 大專學生研究計畫及博士後 — MOST108-2813-C-037-040-B — 8 大專學生研究計畫
108年度大專學生研究計畫-陳承儒(香粧3)( )
|
2019/07/01 ~ 2020/02/29 |
| 19 |
107 — Z 大專學生研究計畫及博士後 — MOST108-2813-C-037-042-B — 8 大專學生研究計畫
108年度大專學生研究計畫-黃育堂(藥學3)( )
|
2019/07/01 ~ 2020/02/29 |
| 20 |
106 — N 國科會(原科技部) — MOST106-2320-B-037-015 — 1 個人型
設計合成三唑喹啉化合物與芳酰基喹喔啉化合物並評估其抗登革病毒活性( )
|
2017/08/01 ~ 2018/07/31 |
| 21 |
105 — N 國科會(原科技部) — MOST103-2320-B-037-011-MY3 — 1 個人型
合成吡唑基喹啉與苯胺基喹啉類衍生物作為抗登革病毒試劑(3/3)( )
|
2016/08/01 ~ 2017/07/31 |
| 22 |
105 — TP 頂尖計畫(高醫) — KMU-TP105E16 —
子計畫十六、合成3‐吡啶喹啉基偶氮衍生物作為甘胺酸氮甲基轉移酶(GNMT)表現之調控劑( )
|
2016/11/01 ~ 2017/10/31 |
| 23 |
105 — TP 頂尖計畫(高醫) — KMU-TP105H08 —
子計畫八、合成芳香環偶氮類衍生物並其抗登革病毒活性( )
|
2016/11/01 ~ 2017/10/31 |
| 24 |
104 — N 國科會(原科技部) — MOST103-2320-B-037-011-MY3 — 1 個人型
合成吡唑基喹啉與苯胺基喹啉類衍生物作為抗登革病毒試劑(2/3)( )
|
2015/08/01 ~ 2017/07/31 |
| 25 |
104 — TP 頂尖計畫(高醫) — KMU-TP104E16 —
子計畫十六、探索新型苯基偶氮衍生物作為調控苷胺酸氮甲基轉移酶(GNMT)表現以治療肝癌( )
|
2015/10/01 ~ 2016/09/30 |
| 26 |
104 — TP 頂尖計畫(高醫) — KMU-TP104H08 —
子計畫八、合成芳香環偶氮類衍生物並評估其抗登革病毒活性( )
|
2015/10/01 ~ 2016/09/30 |
| 27 |
103 — N 國科會(原科技部) — MOST103-2320-B-037-011-MY3 — 1 個人型
合成吡唑基喹啉與苯胺基喹啉類衍生物作為抗登革病毒試劑(1/3)( )
|
2014/08/01 ~ 2017/07/31 |
| 28 |
103 — Q 新聘教師計畫(校內) — KMU-Q104016 —
合成茚[1,2-b]喹喔休類衍生物作為抗腫瘤藥物( )
|
2015/01/01 ~ 2015/12/31 |
| 29 |
103 — TP 頂尖計畫(高醫) — KMU-TP103H08 —
研發具有抗登革熱潛能之喹啉類衍生物( )
|
2014/08/01 ~ 2015/07/31 |
| 30 |
102 — Q 新聘教師計畫(校內) — KMU-Q103028 —
硝基呋喃乙烯茚[1,2-c]喹啉與硝基呋喃乙烯喹啉類化合物之合成及生物活性評估( )
|
2014/01/01 ~ 2014/12/31 |
| 31 |
101 — N 國科會(原科技部) — NSC102-2320-B-037-001 — 1 個人型
2-芳酰基-3-芳香環喹啉類化合物與2-芳酰基-4-苯胺基類化合物之合成及抗登革病毒活性評估( )
|
2013/05/01 ~ 2014/07/31 |
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