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 Education

School — Major — Degree Duration

高雄醫學大學 — 天然藥物研究所(畢) — 博士

Doctorate, Graduate Institute of Natural Products, Kaohsiung Medical University

2008/09 — 2017/06

Charles University in Prague — Faculty of Pharmacy(畢) — 碩士

Master,  ,  

2003/09 — 2008/06

 Intramural Experience

Office/Department/Institute Position Duration
天然藥物研究所 Graduate Institute of Natural Products   Assistant Professor 2023/08/01 —  
天然藥物研究所 Graduate Institute of Natural Products   Assistant Professor 2021/08/01 — 2023/07/31

 Extramural Experience

 

 Discipline

 

 Research & Technology Platform Open to the Outside

https://www.scopus.com/authid/detail.uri?authorId=54393201400, https://scholar.google.com/citations?hl=en&user=VEOwK0cAAAAJ

 Interested Area(s)for Interdisciplinary Research

發展來自歐洲亞洲和非洲國​​家的生物活性天然產品

Discovery of bioactive natural products from European, Asian and African countries

 Area(s) of Expertise & Research

天然物化學 傳統和民間藥物 抗過敏炎症 生物信息學工具 新藥開發

Natural product chemistry. Traditional and folk medicines. Anti-allergic inflammation. Bioinformatics tools. New drug development.

 Publication

NO Publication
1

Development on potential skin anti-aging agents of Cosmos caudatus Kunth via inhibition of collagenase, MMP-1 and MMP-3 activities.
盧燕奇, 胡皓竣, 余思穎, 蔡逸宏, 柯麥可, 吳永昌*, 張芳榮*, 陳瑩容* - - 1 - PHYTOMEDICINE : INTERNATIONAL JOURNAL OF PHYTOTHERAPY AND PHYTOPHARMACOLOGY - PHYTOMEDICINE 2023 110卷(2023期):154643頁
(IF: 6.656, 領域排名: 1, 領域期刊數: 30, 領域排名: 3.33%)

Development on potential skin anti-aging agents of Cosmos caudatus Kunth via inhibition of collagenase, MMP-1 and MMP-3 activities.
Yen Chi Loo, Hao-Chun Hu, Szu-Yin Yu, Yi-Hong Tsai, Michal Korinek, Yang-Chang Wu*, Fang-Rong Chang*, Ying-Jung Chen* - - 1 - PHYTOMEDICINE : INTERNATIONAL JOURNAL OF PHYTOTHERAPY AND PHYTOPHARMACOLOGY - PHYTOMEDICINE 2023;110(2023):154643
(IF: 6.656, Journal Ranking: 1, Number of Journals of this Field: 30, Ranking: 3.33%)

2

Anti-viral and Anti-inflammatory Isoflavonoids from Ukrainian Iris aphylla Rhizomes: Structure-Activity Relationship Coupled with ChemGPS-NP Analysis.
Mykhailenko O#, 謝宗帆#, El-Shazly M, Nikishin A, Kovalyov V, Shynkarenko P, Ivanauskas L, 陳炳宏, 洪錦堂, 黃聰龍, Georgiyants V, 柯麥可* - - 1 - PLANTA MEDICA - PLANTA MEDICA 2023 89卷(11期):1063-1073頁
(IF: 2.7, 領域排名: 92, 領域期刊數: 239, 領域排名: 38.49%)

Anti-viral and Anti-inflammatory Isoflavonoids from Ukrainian Iris aphylla Rhizomes: Structure-Activity Relationship Coupled with ChemGPS-NP Analysis.
Olha Mykhailenko, Chung-Fan Hsieh, Mohamed El-Shazly, Alexander Nikishin, Vladimir Kovalyov, Pavlo Shynkarenko, Liudas Ivanauskas, Bing-Hung Chen, Jim-Tong Horng, Tsong-Long Hwang, Victoriya Georgiyants, Michal Korinek - - 1 - PLANTA MEDICA - PLANTA MEDICA 2023;89(11):1063-1073
(IF: 2.7, Journal Ranking: 92, Number of Journals of this Field: 239, Ranking: 38.49%)

3

Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release.
Fayez S#, Gamal El-Din MI#, Moghannem SA, Azam F, El-Shazly M*, 柯麥可, 陳俞利, 黃聰龍*, Fahmy NM - - 1 - FRONTIERS IN PHARMACOLOGY - FRONTIERS IN PHARMACOLOGY 2023 14卷(-期):1218315頁
(IF: 5.6, 領域排名: 44, 領域期刊數: 278, 領域排名: 15.83%)

Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release.
Shaimaa Fayez, Mariam I Gamal El-Din, Saad A Moghannem, Faizul Azam, Mohamed El-Shazly, Michal Korinek, Yu-Li Chen, Tsong-Long Hwang, Nouran M Fahmy - - 1 - FRONTIERS IN PHARMACOLOGY - FRONTIERS IN PHARMACOLOGY 2023;14(-):1218315
(IF: 5.6, Journal Ranking: 44, Number of Journals of this Field: 278, Ranking: 15.83%)

4

Comparative LC-LTQ-MS-MS Analysis of the Leaf Extracts of Lantana camara and Lantana montevidensis Growing in Egypt with Insights into Their Antioxidant, Anti-Inflammatory, and Cytotoxic Activities.
Mariam I Gamal El-Din, Nouran M Fahmy, Fulin Wu, Maha M Salem, Omar M Khattab, Hesham R El-Seedi, 柯麥可, 黃聰龍*, Ahmed K Osman, Mohamed El-Shazly*, Shaimaa Fayez - - 1 - PLANTS (BASEL, SWITZERLAND) - PLANTS-BASEL 2022 11卷(13期):1699頁
(IF: 4.658, 領域排名: 39, 領域期刊數: 238, 領域排名: 16.39%)

Comparative LC-LTQ-MS-MS Analysis of the Leaf Extracts of Lantana camara and Lantana montevidensis Growing in Egypt with Insights into Their Antioxidant, Anti-Inflammatory, and Cytotoxic Activities.
Mariam I Gamal El-Din, Nouran M Fahmy, Fulin Wu, Maha M Salem, Omar M Khattab, Hesham R El-Seedi, Michal Korinek, Tsong-Long Hwang*, Ahmed K Osman, Mohamed El-Shazly*, Shaimaa Fayez - - 1 - PLANTS (BASEL, SWITZERLAND) - PLANTS-BASEL 2022;11(13):1699
(IF: 4.658, Journal Ranking: 39, Number of Journals of this Field: 238, Ranking: 16.39%)

5

Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M-pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis
Ibrahim S Uras, 柯麥可, Amgad Albohy, Basma S Abdulrazik, Wenhan Lin, Sherif S Ebada*, Belma Konuklugil* - - 1 - CHEMISTRYSELECT - CHEMISTRYSELECT 2022 7卷(12期):e202200130頁
(IF: 2.307, 領域排名: 119, 領域期刊數: 179, 領域排名: 66.48%)

Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M-pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis
Ibrahim S Uras, Michal Korinek, Amgad Albohy, Basma S Abdulrazik, Wenhan Lin, Sherif S Ebada*, Belma Konuklugil* - - 1 - CHEMISTRYSELECT - CHEMISTRYSELECT 2022;7(12):e202200130
(IF: 2.307, Journal Ranking: 119, Number of Journals of this Field: 179, Ranking: 66.48%)

6

Pharmacological Potential and Chemical Composition of Crocus sativus Leaf Extracts
Olha Mykhailenko, Vilma Petrikaite, 柯麥可, 張芳榮, Mohamed El-Shazly*, 顏嘉宏, Ivan Bezruk, 陳炳宏, Chung-Fan Hsieh, Dmytro Lytkin, Liudas Ivanauskas, Victoriya Georgiyants, 黃聰龍* - - 1 - MOLECULES (BASEL, SWITZERLAND) - MOLECULES 2022 27卷(1期):10頁
(IF: 4.6, 領域排名: 97, 領域期刊數: 285, 領域排名: 34.04%)

Pharmacological Potential and Chemical Composition of Crocus sativus Leaf Extracts
Olha Mykhailenko, Vilma Petrikaite, Michal Korinek, Fang-Rong Chang, Mohamed El-Shazly*, Chia-Hung Yen, Ivan Bezruk, Bing-Hung Chen, Chung-Fan Hsieh, Dmytro Lytkin, Liudas Ivanauskas, Victoriya Georgiyants, Tsong-Long Hwang* - - 1 - MOLECULES (BASEL, SWITZERLAND) - MOLECULES 2022;27(1):10
(IF: 4.6, Journal Ranking: 97, Number of Journals of this Field: 285, Ranking: 34.04%)

7

Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo.
柯麥可, Pei-Shan Hsieh, Yu-Li Chen, 謝珮文, Shih-Hsin Chang, Yi-Hsiu Wu, 黃聰龍* - - 1 - BIOCHEMICAL PHARMACOLOGY - BIOCHEMICAL PHARMACOLOGY 2021 190卷(-期):114596頁
(IF: 6.1, 領域排名: 46, 領域期刊數: 279, 領域排名: 16.49%)

Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo.
Michal Korinek, Pei-Shan Hsieh, Yu-Li Chen, Pei-Wen Hsieh, Shih-Hsin Chang, Yi-Hsiu Wu, Tsong-Long Hwang* - - 1 - BIOCHEMICAL PHARMACOLOGY - BIOCHEMICAL PHARMACOLOGY 2021;190(-):114596
(IF: 6.1, Journal Ranking: 46, Number of Journals of this Field: 279, Ranking: 16.49%)

8

Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs.
柯麥可, Heba Handoussa*, 蔡逸宏, You-Ying Chen, Meng-Hua Chen, Zan-Wei Chiou, Yu Fang, 張芳榮, 顏嘉宏, Chung-Fan Hsieh, 陳炳宏, Mohamed El-Shazly*, 黃聰龍* - - 1 - FRONTIERS IN PHARMACOLOGY - FRONTIERS IN PHARMACOLOGY 2021 12卷(-期):674095頁
(IF: 5.988, 領域排名: 50, 領域期刊數: 279, 領域排名: 17.92%)

Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs.
Michal Korinek, Heba Handoussa*, Yi-Hong Tsai, You-Ying Chen, Meng-Hua Chen, Zan-Wei Chiou, Yu Fang, Fang-Rong Chang, Chia-Hung Yen, Chung-Fan Hsieh, Bing-Hung Chen, Mohamed El-Shazly*, Tsong-Long Hwang* - - 1 - FRONTIERS IN PHARMACOLOGY - FRONTIERS IN PHARMACOLOGY 2021;12(-):674095
(IF: 5.988, Journal Ranking: 50, Number of Journals of this Field: 279, Ranking: 17.92%)

9

Anti-Allergic, Anti-Inflammatory, and Anti-Hyperglycemic Activity of Chasmanthe aethiopica Leaf Extract and Its Profiling Using LC/MS and GLC/MS
Iriny M Ayoub, 柯麥可, Mohamed El-Shazly, Bernhard Wetterauer, Hesham A El-Beshbishy, Tsong-Long Hwang, 陳炳宏, 張芳榮*, Michael Wink*, Abdel Nasser B Singab*, Fadia S Youssef - - 1 - PLANTS (BASEL, SWITZERLAND) - PLANTS-BASEL 2021 10卷(6期):1118頁
(IF: 4.658, 領域排名: 39, 領域期刊數: 238, 領域排名: 16.39%)

Anti-Allergic, Anti-Inflammatory, and Anti-Hyperglycemic Activity of Chasmanthe aethiopica Leaf Extract and Its Profiling Using LC/MS and GLC/MS
Iriny M Ayoub, Michal Korinek, Mohamed El-Shazly, Bernhard Wetterauer, Hesham A El-Beshbishy, Tsong-Long Hwang, Bing-Hung Chen, Fang-Rong Chang*, Michael Wink*, Abdel Nasser B Singab*, Fadia S Youssef - - 1 - PLANTS (BASEL, SWITZERLAND) - PLANTS-BASEL 2021;10(6):1118
(IF: 4.658, Journal Ranking: 39, Number of Journals of this Field: 238, Ranking: 16.39%)

10

Decoding Multiple Biofunctions of Maca on Its Anti-allergic, Anti-inflammatory, Anti-thrombotic, and Pro-angiogenic Activities.
Kartiko Arif Purnomo, 柯麥可, 蔡逸宏, 胡皓竣, Yi-Hsuan Wang, Anders Backlund, Tsong-Long Hwang, 陳炳宏, Shih-Wei Wang, 吳志中, 張芳榮* - - 1 - JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY - JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021 69卷(40期):11856-11866頁
(IF: 5.895, 領域排名: 6, 領域期刊數: 59, 領域排名: 10.17%)

Decoding Multiple Biofunctions of Maca on Its Anti-allergic, Anti-inflammatory, Anti-thrombotic, and Pro-angiogenic Activities.
Kartiko Arif Purnomo, Michal Korinek, Yi-Hong Tsai, Hao-Chun Hu, Yi-Hsuan Wang, Anders Backlund, Tsong-Long Hwang, Bing-Hung Chen, Shih-Wei Wang, Chin-Chung Wu, Fang-Rong Chang* - - 1 - JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY - JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021;69(40):11856-11866
(IF: 5.895, Journal Ranking: 6, Number of Journals of this Field: 59, Ranking: 10.17%)

11

Anti-Inflammatory, Antiallergic, and COVID-19 Main Protease (M-pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus terreus
Ibrahim S. Uras, Sherif S. Ebada*, 柯麥可, Amgad Albohy, Basma S. Abdulrazik, 汪依璿, 陳炳宏, 錦堂洪, Wenhan Lin*, 黃聰龍*, Belma Konuklugil*. - - 1 - Molecules - MOLECULES 2021 26卷(11期):3354頁
(IF: 4.927, 領域排名: 114, 領域期刊數: 296, 領域排名: 38.51%)

Anti-Inflammatory, Antiallergic, and COVID-19 Main Protease (M-pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus terreus
Ibrahim S. Uras, Sherif S. Ebada*, Michal Korinek, Amgad Albohy, Basma S. Abdulrazik, Yi-Hsuan Wang, Bing-Hung Chen, Jim-Tong Horng, Wenhan Lin*, Tsong-Long Hwang*, Belma Konuklugil*. - - 1 - Molecules - MOLECULES 2021;26(11):3354
(IF: 4.927, Journal Ranking: 114, Number of Journals of this Field: 296, Ranking: 38.51%)

12

Bio-guided bioactive profiling and HPLC-DAD fingerprinting of Ukrainian saffron (Crocus sativus stigmas): moving from correlation toward causation.
Olha Mykhailenko, Vilma Petrikaite, 柯麥可*, Mohamed El-Shazly, 陳炳宏, 顏嘉宏, 謝宗帆, Ivan Bezruk, Asta Dabrišiūtė, Liudas Ivanauskas, Victoriya Georgiyants, 黃聰龍* - - 1 - BMC COMPLEMENTARY MEDICINE AND THERAPIES - BMC COMPLEMENTARY MEDICINE AND THERAPIES 2021 21卷(1期):203頁
(IF: 2.838, 領域排名: 15, 領域期刊數: 30, 領域排名: 50.00%)

Bio-guided bioactive profiling and HPLC-DAD fingerprinting of Ukrainian saffron (Crocus sativus stigmas): moving from correlation toward causation.
Olha Mykhailenko, Vilma Petrikaite, Michal Korinek*, Mohamed El-Shazly, Bing-Hung Chen, Chia-Hung Yen, Chung-Fan Hsieh, Ivan Bezruk, Asta Asta Dabrišiūtė, Liudas Ivanauskas, Victoriya Georgiyants, Tsong-Long Hwang* - - 1 - BMC COMPLEMENTARY MEDICINE AND THERAPIES - BMC COMPLEMENTARY MEDICINE AND THERAPIES 2021;21(1):203
(IF: 2.838, Journal Ranking: 15, Number of Journals of this Field: 30, Ranking: 50.00%)

13

α-Glucosidase inhibitors from the bark extract of ethno-antidiabetic Ceriops tagal (Perr.) CB Rob
Bernard S. Canusa, Ivan L. Lawag, Oliver B. Villaflores, Vitthal D. Wagh, 柯麥可, 蔡逸宏, 張芳榮, Ma. Alicia M. Aguinaldo - - 9 - Philippine Journal of Science - 2021 151卷(S1期):25-60頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

α-Glucosidase inhibitors from the bark extract of ethno-antidiabetic Ceriops tagal (Perr.) CB Rob
Bernard S. Canusa, Ivan L. Lawag, Oliver B. Villaflores, Vitthal D. Wagh, Michal Korinek, Yi-Hong Tsai, Fang-Rong Chang, Ma. Alicia M. Aguinaldo - - 9 - Philippine Journal of Science - 2021;151(S1):25-60
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

14

Phytochemical research and anti-inflammatory activity of the dry extracts from Northern highbush blueberry leaves
Oleksandr Stremoukhov, Oleh Koshovyi, Mykola Komisarenko, Igor Kireyev, Andriy Gudzenko, 柯麥可, 黃聰龍, Meng-Hua Chen, Olha Mykhailenko. - - 9 - ScienceRise: Pharmaceutical Science - 2021 2卷(30期):40–48頁
(IF: 0, 領域排名: 0, 領域期刊數: 0, 領域排名: -%)

Phytochemical research and anti-inflammatory activity of the dry extracts from Northern highbush blueberry leaves
Oleksandr Stremoukhov, Oleh Koshovyi, Mykola Komisarenko, Igor Kireyev, Andriy Gudzenko, Michal Korinek, Tsong-Long Hwang, Meng-Hua Chen, Olha Mykhailenko. - - 9 - ScienceRise: Pharmaceutical Science - 2021;2(30):40–48
(IF: 0, Journal Ranking: 0, Number of Journals of this Field: 0, Ranking: -%)

15

Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease.
Chih-Chao Chiang, 柯麥可#, Wei-Jen Cheng#, 黃聰龍* - - 1 - FRONTIERS IN PHARMACOLOGY - FRONTIERS IN PHARMACOLOGY 2020 11卷(-期):572009頁
(IF: 5.988, 領域排名: 50, 領域期刊數: 279, 領域排名: 17.92%)

Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease.
Chih-Chao Chiang, Michal Korinek#, Wei-Jen Cheng#, Tsong-Long Hwang* - - 1 - FRONTIERS IN PHARMACOLOGY - FRONTIERS IN PHARMACOLOGY 2020;11(-):572009
(IF: 5.988, Journal Ranking: 50, Number of Journals of this Field: 279, Ranking: 17.92%)

16

Neutrophils in Psoriasis.
Chih-Chao Chiang, Wei-Jen Cheng, 柯麥可, Cheng-Yu Lin, 黃聰龍* - - 1 - FRONTIERS IN IMMUNOLOGY - FRONTIERS IN IMMUNOLOGY 2019 10卷(-期):2376頁
(IF: 5.085, 領域排名: 39, 領域期刊數: 159, 領域排名: 24.53%)

Neutrophils in Psoriasis.
Chih-Chao Chiang, Wei-Jen Cheng, Michal Korinek, Cheng-Yu Lin, Tsong-Long Hwang* - - 1 - FRONTIERS IN IMMUNOLOGY - FRONTIERS IN IMMUNOLOGY 2019;10(-):2376
(IF: 5.085, Journal Ranking: 39, Number of Journals of this Field: 159, Ranking: 24.53%)

 Project

NO
YEAR — Source — No — Type
Project Name
Duration
1
112 — N 國科會(原科技部) — NSTC112-2320-B-037-012 — 1 個人型
利用大數據分子網絡技術從茄苳開發出調節免疫類疾病的天然產物( )
2023/08/01 ~ 2024/07/31
2
111 — Q 新聘教師計畫(校內) — KMU-Q112006 —  
防己和其攙假偽藥的植化素研究( )
2023/01/01 ~ 2023/12/31
3
110 — N 國科會(原科技部) — MOST111-2320-B-037-007 — 1 個人型
基於國際合作發展富含抗新冠病毒生物鹼的天然萃取物( )
2022/06/01 ~ 2023/05/31

 Patent